All Stories

  1. Pathogenic Keratinocyte States and Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa

    Article • November 2025, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe, Professor Fiona M Watt

  2. Cell volume regulates terminal differentiation of cultured human epidermal keratinocytes

    Article • Journal of Cell Science, July 2025, The Company of Biologists

    Professor Fiona M Watt

  3. Controlled anarchy

    Article • EMBO Reports, May 2025, Springer Science + Business Media

    Professor Fiona M Watt

  4. Cell volume regulates terminal differentiation of cultured human epidermal keratinocytes

    Article • December 2024, Cold Spring Harbor Laboratory Press

    Professor Fiona M Watt

  5. Caspase-8-dependent autophagy regulates neutrophil infiltration in oral squamous cell carcinoma

    Article • Proceedings of the National Academy of Sciences, December 2024, Proceedings of the National Academy of Sciences

    Professor Fiona M Watt

  6. Emergence and properties of adult mammalian epidermal stem cells

    Article • Developmental Biology, November 2024, Elsevier

    Professor Fiona M Watt

  7. Sustainability in the lab: funders and researchers should sign up and partner up

    Article • Nature, October 2024, Springer Science + Business Media

    Professor Fiona M Watt

  8. Transplanted fibroblasts take the pressure

    Article • Science, September 2024, American Association for the Advancement of Science

    Professor Fiona M Watt

  9. Neutral evolution of snoRNA Host Gene long non-coding RNA affects cell fate control

    Article • The EMBO Journal, July 2024, Springer Science + Business Media

    Professor Fiona M Watt

  10. Multiscale spatial mapping of cell populations across anatomical sites in healthy human skin and basal cell carcinoma

    Article • Proceedings of the National Academy of Sciences, January 2024, Proceedings of the National Academy of Sciences

    Professor Fiona M Watt

  11. Neutral evolution of snoRNA Host Gene long non-coding RNA affects cell fate control

    Article • December 2023, Cold Spring Harbor Laboratory Press

    Professor Fiona M Watt

  12. Single-cell RNA sequencing of human epidermis identifies Lunatic fringe as a novel regulator of the stem cell compartment

    Article • Stem Cell Reports, November 2023, Elsevier

    Professor Fiona M Watt

  13. Myc-dependent dedifferentiation of Gata6+ epidermal cells resembles reversal of terminal differentiation

    Article • Nature Cell Biology, September 2023, Springer Science + Business Media

    Professor Fiona M Watt

  14. How to avoid mistakes in science publications

    Article • EMBO Reports, September 2023, Springer Science + Business Media

    Professor Fiona M Watt

  15. LYVE-1+ macrophages form a collaborative CCR5-dependent perivascular niche that influences chemotherapy responses in murine breast cancer

    Article • Developmental Cell, September 2023, Elsevier

    Professor Fiona M Watt

  16. Caspase activation in tumour‐infiltrating lymphocytes is associated with lymph node metastasis in oral squamous cell carcinoma

    Article • The Journal of Pathology, July 2023, Wiley

    Professor Fiona M Watt

  17. Modelling renal defects in Bardet-Biedl syndrome patients using human iPS cells

    Article • Frontiers in Cell and Developmental Biology, June 2023, Frontiers

    Professor Fiona M Watt

  18. A reductionist approach to determine the effect of cell-cell contact on human epidermal stem cell differentiation

    Article • Acta Biomaterialia, September 2022, Elsevier

    Professor Fiona M Watt

  19. Understanding Human Epidermal Stem Cells at Single-Cell Resolution

    Article • Journal of Investigative Dermatology, August 2022, Elsevier

    Professor Fiona M Watt

  20. Funding: end ‘publish or perish’ for postdocs

    Article • Nature, June 2022, Springer Science + Business Media

    Professor Fiona M Watt

  21. Embigin is a fibronectin receptor that affects sebaceous gland differentiation and metabolism

    Article • Developmental Cell, June 2022, Elsevier

    Professor Fiona M Watt

  22. Functional genomics and the future of iPSCs in disease modeling

    Article • Stem Cell Reports, May 2022, Elsevier

    Professor Fiona M Watt

  23. Angiotensin-Converting Enzyme 2 Expression Is Detectable in Keratinocytes, Cutaneous Appendages, and Blood Vessels by Multiplex RNA In Situ Hybridization

    Article • Advances in Skin & Wound Care, April 2022, Wolters Kluwer Health

    Professor Fiona M Watt

  24. An HNF1α truncation associated with maturity-onset diabetes of the young impairs pancreatic progenitor differentiation by antagonizing HNF1β function

    Article • Cell Reports, March 2022, Elsevier

    Professor Fiona M Watt

  25. Mammalian Epidermis: A Compendium of Lipid Functionality

    Article • Frontiers in Physiology, January 2022, Frontiers

    Professor Fiona M Watt

  26. Dynamic regulation of human epidermal differentiation by adhesive and mechanical forces

    Article • January 2022, Elsevier

    Professor Fiona M Watt

  27. Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage

    Article • eLife, December 2021, eLife

    Professor Fiona M Watt

  28. Gradient boosting approaches can outperform logistic regression for risk prediction in cutaneous allergy

    Article • Contact Dermatitis, December 2021, Wiley

    Professor Fiona M Watt

  29. Pluripotent Stem Cell-Derived Hepatocytes Inhibit T Cell Proliferation In Vitro through Tryptophan Starvation

    Article • Cells, December 2021, MDPI AG

    Professor Fiona M Watt

  30. Plating human iPSC lines on micropatterned substrates reveals role for ITGB1 nsSNV in endoderm formation

    Article • Stem Cell Reports, November 2021, Elsevier

    Dr Davide Danovi, Professor Fiona M Watt

  31. How COVID-19 has changed medical research funding

    Article • Interface Focus, October 2021, Royal Society Publishing

    Professor Fiona M Watt

  32. Translational control of stem cell function

    Article • Nature Reviews Molecular Cell Biology, July 2021, Springer Science + Business Media

    Professor Fiona M Watt

  33. Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair

    Article • Frontiers in Cell and Developmental Biology, May 2021, Frontiers

    Professor Fiona M Watt

  34. Employing core regulatory circuits to define cell identity

    Article • The EMBO Journal, May 2021, Springer Science + Business Media

    Professor Fiona M Watt

  35. Differential Expression of Insulin-Like Growth Factor 1 and Wnt Family Member 4 Correlates With Functional Heterogeneity of Human Dermal Fibroblasts

    Article • Frontiers in Cell and Developmental Biology, April 2021, Frontiers

    Professor Fiona M Watt

  36. Fibrotic enzymes modulate wound‐induced skin tumorigenesis

    Article • EMBO Reports, March 2021, Springer Science + Business Media

    Professor Fiona M Watt

  37. The transCampus Metabolic Training Programme Explores the Link of SARS-CoV-2 Virus to Metabolic Disease

    Article • Hormone and Metabolic Research, March 2021, Thieme Publishing Group

    Prof. Dr. Jens Pietzsch, Manuel Mayr, Professor Fiona M Watt

  38. Developmental cell programs are co-opted in inflammatory skin disease

    Article • Science, January 2021, American Association for the Advancement of Science

    Professor Fiona M Watt

  39. A blueprint for translational regenerative medicine

    Article • Science Translational Medicine, December 2020, American Association for the Advancement of Science

    Professor Fiona M Watt

  40. Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology

    Article • Nature Communications, November 2020, Springer Science + Business Media

    Professor Fiona M Watt, Dr Trevor A Graham

  41. Applications and future directions for optical coherence tomography in dermatology*

    Article • British Journal of Dermatology, November 2020, Oxford University Press (OUP)

    Professor Fiona M Watt

  42. Contribution of GATA6 to homeostasis of the human upper pilosebaceous unit and acne pathogenesis

    Article • Nature Communications, October 2020, Springer Science + Business Media

    Professor Fiona M Watt

  43. Clinically Relevant Vulnerabilities of Deep Machine Learning Systems for Skin Cancer Diagnosis

    Article • Journal of Investigative Dermatology, September 2020, Elsevier

    Professor Nicholas Luscombe, Professor Fiona M Watt

  44. Human epidermal stem cell differentiation is modulated by specific lipid subspecies

    Article • Proceedings of the National Academy of Sciences, August 2020, Proceedings of the National Academy of Sciences

    Professor Fiona M Watt

  45. Population-scale proteome variation in human induced pluripotent stem cells

    Article • eLife, August 2020, eLife

    Professor Fiona M Watt

  46. UK funders learn from COVID-19 ‘white-water ride’

    Article • Nature, July 2020, Springer Science + Business Media

    Professor Fiona M Watt

  47. Regulation of ERK basal and pulsatile activity control proliferation and exit from the stem cell compartment in mammalian epidermis

    Article • Proceedings of the National Academy of Sciences, July 2020, Proceedings of the National Academy of Sciences

    Professor Fiona M Watt

  48. CD147 (BSG) but not ACE2 expression is detectable in vascular endothelial cells within single cell RNA sequencing datasets derived from multiple tissues in healthy individuals

    Article • May 2020, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe, Professor Fiona M Watt

  49. ERK basal and pulsatile activity are differentially regulated in mammalian epidermis to control proliferation and exit from the stem cell compartment

    Article • April 2020, Cold Spring Harbor Laboratory Press

    Professor Fiona M Watt

  50. Publisher Correction: Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression

    Article • Nature Communications, March 2020, Springer Science + Business Media

    Professor Fiona M Watt

  51. Map clusters of diseases to tackle multimorbidity

    Article • Nature, March 2020, Springer Science + Business Media

    Professor Fiona M Watt

  52. Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression

    Article • Nature Communications, February 2020, Springer Science + Business Media

    Dr Davis J McCarthy, Professor Fiona M Watt

  53. A framework for advancing our understanding of cancer-associated fibroblasts

    Article • Nature Reviews Cancer, January 2020, Springer Science + Business Media

    Professor Fiona M Watt

  54. What is AI? Applications of artificial intelligence to dermatology

    Article • British Journal of Dermatology, January 2020, Wiley

    Professor Fiona M Watt, Professor Nicholas Luscombe

  55. Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Mucosa in Response to Physiological Stress

    Article • Cell Stem Cell, December 2019, Elsevier

    Professor Fiona M Watt

  56. NOTCH1 signaling in oral squamous cell carcinoma via a TEL2/SERPINE1 axis

    Article • Oncotarget, October 2019, Impact Journals, LLC

    Professor Fiona M Watt

  57. High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation–associated versus preneurulation-associated fate patterning

    Article • PLoS Biology, October 2019, PLOS

    Professor Fiona M Watt, Dr Davide Danovi

  58. Delta-like 1-mediated cis-inhibition of Jagged1/2 signalling inhibits differentiation of human epidermal cells in culture

    Article • Scientific Reports, July 2019, Springer Science + Business Media

    Professor Fiona M Watt

  59. Mechanisms, Hallmarks, and Implications of Stem Cell Quiescence

    Article • Stem Cell Reports, June 2019, Elsevier

    Professor Fiona M Watt

  60. The role of keratins in modulating carcinogenesis via communication with cells of the immune system

    Article • Cell Stress, April 2019, Shared Science Publishers OG

    Professor Fiona M Watt

  61. Mutant Lef1 controls Gata6 in sebaceous gland development and cancer

    Article • The EMBO Journal, March 2019, EMBO

    Professor Fiona M Watt

  62. Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02

    Article • Nature Communications, March 2019, Springer Science + Business Media

    Professor Fiona M Watt

  63. Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors

    Article • Cell Reports, February 2019, Elsevier

    Professor Fiona M Watt, Erika Wiseman, Dr Davide Danovi

  64. Patterning of human epidermal stem cells on undulating elastomer substrates reflects differences in cell stiffness

    Article • Acta Biomaterialia, January 2019, Elsevier

    Professor Fiona M Watt

  65. Bench to bedside: Current advances in regenerative medicine

    Article • Current Opinion in Cell Biology, December 2018, Elsevier

    Professor Fiona M Watt

  66. Micro-scaled topographies direct differentiation of human epidermal stem cells

    Article • Acta Biomaterialia, December 2018, Elsevier

    Professor Fiona M Watt

  67. High-throughput micro-patterning platform reveals Nodal-dependent dissection of peri-gastrulation-associated versus pre-neurulation associated fate patterning

    Article • November 2018, Cold Spring Harbor Laboratory Press

    Professor Fiona M Watt, Dr Davide Danovi

  68. Hair follicle epidermal stem cells define a niche for tactile sensation

    Article • eLife, October 2018, eLife

    Professor Fiona M Watt

  69. Lrig1 marks a population of gastric epithelial cells capable of long-term tissue maintenance and growth in vitro

    Article • Scientific Reports, October 2018, Springer Science + Business Media

    Professor Fiona M Watt

  70. Dynamic culture substrates that mimic the topography of the epidermal-dermal junction

    Article • Tissue Engineering Part A, October 2018, Mary Ann Liebert Inc

    Professor Fiona M Watt

  71. The reward of great collaborations

    Article • Nature Cell Biology, August 2018, Springer Science + Business Media

    Professor Fiona M Watt

  72. Immunomodulatory role of Keratin 76 in oral and gastric cancer

    Article • Nature Communications, August 2018, Springer Science + Business Media

    Professor Fiona M Watt

  73. Fibroblast state switching orchestrates dermal maturation and wound healing

    Article • Molecular Systems Biology, August 2018, EMBO

    Professor Fiona M Watt

  74. Loxl2 is dispensable for dermal development, homeostasis and tumour stroma formation

    Article • PLOS One, June 2018, PLOS

    Professor Fiona M Watt

  75. Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation

    Article • June 2018, Cold Spring Harbor Laboratory Press

    Professor Fiona M Watt

  76. Defining Adult Stem Cells by Function, not by Phenotype

    Article • Annual Review of Biochemistry, June 2018, Annual Reviews

    Professor Fiona M Watt

  77. 1351 Investigation of the molecular identity of the junctional zone in human

    Article • Journal of Investigative Dermatology, May 2018, Elsevier

    Professor Fiona M Watt

  78. 1354 Spatial and single-cell transcriptional profiling identifies functionally distinct human dermal fibroblast subpopulations

    Article • Journal of Investigative Dermatology, May 2018, Elsevier

    Professor Fiona M Watt

  79. Skin Cell Heterogeneity in Development, Wound Healing, and Cancer

    Article • Trends in Cell Biology, May 2018, Elsevier

    Professor Fiona M Watt

  80. Diverse mechanisms for endogenous regeneration and repair in mammalian organs

    Article • Nature, May 2018, Springer Science + Business Media

    Professor Fiona M Watt

  81. IMMUNOMODULATORY ROLE OF KERATIN 76 IN ORAL AND GASTRIC CANCER

    Article • April 2018, Cold Spring Harbor Laboratory Press

    Professor Fiona M Watt

  82. Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations

    Article • Journal of Investigative Dermatology, April 2018, Elsevier

    Professor Fiona M Watt

  83. An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis

    Article • Nature, April 2018, Springer Science + Business Media

    Professor Fiona M Watt

  84. (More) women in science

    Article • Nature Reviews Molecular Cell Biology, March 2018, Nature

    Professor Fiona M Watt

  85. Myosin 10 is involved in murine pigmentation

    Article • Experimental Dermatology, March 2018, Wiley

    Professor Fiona M Watt

  86. Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate in neighbouring cells

    Article • January 2018, Springer Science + Business Media

    Professor Fiona M Watt

  87. Fibroblast heterogeneity: implications for human disease

    Article • Journal of Clinical Investigation, January 2018, American Society for Clinical Investigation

    Professor Fiona M Watt

  88. Homeostasis, regeneration and tumour formation in the mammalian epidermis

    Article • The International Journal of Developmental Biology, January 2018, UBC Press

    Professor Fiona M Watt

  89. The Human Cell Atlas

    Article • eLife, December 2017, eLife

    Professor Fiona M Watt, Piero Carninci

  90. Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation

    Article • Science Translational Medicine, November 2017, American Association for the Advancement of Science

    Professor Fiona M Watt

  91. Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth

    Article • Journal of Investigative Dermatology, November 2017, Elsevier

    Professor Fiona M Watt

  92. Spatial constraints govern competition of mutant clones in human epidermis

    Article • Nature Communications, October 2017, Nature

    Professor Fiona M Watt

  93. A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis

    Article • eLife, October 2017, eLife

    Professor Fiona M Watt

  94. 085 Type XVII collagen suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis

    Article • Journal of Investigative Dermatology, October 2017, Elsevier

    Professor Fiona M Watt

  95. 554 Dissecting fibroblast heterogeneity in skin cancer

    Article • Journal of Investigative Dermatology, October 2017, Elsevier

    Professor Fiona M Watt

  96. Type XVII collagen coordinates proliferation in the interfollicular epidermis

    Article • eLife, July 2017, eLife

    Professor Fiona M Watt

  97. ERK MAPK activation bursts and propagation in adult and embryonic mouse skin

    Article • Mechanisms of Development, July 2017, Elsevier

    Professor Fiona M Watt

  98. Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate in neighbouring cells

    Article • June 2017, Cold Spring Harbor Laboratory Press

    Professor Fiona M Watt

  99. The adaptive immune response to cardiac injury—the true roadblock to effective regenerative therapies?

    Article • npj Regenerative Medicine, June 2017, Springer Science + Business Media

    Professor Fiona M Watt

  100. Erratum: Corrigendum: Common genetic variation drives molecular heterogeneity in human iPSCs

    Article • Nature, June 2017, Springer Science + Business Media

    Professor Fiona M Watt, Dr Davis J McCarthy, Dr Davide Danovi

  101. Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem cell properties

    Article • Nature Cell Biology, May 2017, Nature

    Professor Fiona M Watt

  102. Common genetic variation drives molecular heterogeneity in human iPSCs

    Article • Nature, May 2017, Nature

    Dr Angela Goncalves, Dr Davis J McCarthy, Professor Fiona M Watt, Dr Davide Danovi

  103. Distinct wave patterns of ERK MAPK activation control epidermal proliferation and migration in vivo

    Article • Journal of Dermatological Science, May 2017, Elsevier

    Professor Fiona M Watt

  104. Repeal and Replace: Adipocyte Regeneration in Wound Repair

    Article • Cell Stem Cell, April 2017, Elsevier

    Professor Fiona M Watt

  105. A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human epidermal stem cells

    Article • Nature Communications, March 2017, Nature

    Professor Fiona M Watt

  106. Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection

    Article • Arabian archaeology and epigraphy, February 2017, Wiley

    DR lesley smyth, Professor Fiona M Watt

  107. Reply to Chi et al.

    Article • Journal of Investigative Dermatology, January 2017, Elsevier

    Professor Fiona M Watt

  108. Live image tricky cells and integrate the data with datasets without the dimension of time

    Article • SLAS DISCOVERY, October 2016, SAGE Publications

    Dr Davide Danovi, Professor Fiona M Watt

  109. Integrative genomic and functional analysis of human oral squamous cell carcinoma cell lines reveals synergistic effects of FAT1 and CASP8 inactivation

    Article • Cancer Letters, September 2016, Elsevier

    Professor Fiona M Watt

  110. Engineered Microenvironments to Direct Epidermal Stem Cell Behavior at Single-Cell Resolution

    Article • Developmental Cell, September 2016, Elsevier

    Professor Fiona M Watt

  111. Pelota Regulates Epidermal Differentiation by Modulating BMP and PI3K/AKT Signaling Pathways

    Article • Journal of Investigative Dermatology, August 2016, Elsevier

    Professor Fiona M Watt

  112. CIRM and UKRMP: Different Ways to Invest in Regenerative Medicine

    Article • Cell Stem Cell, July 2016, Elsevier

    Professor Fiona M Watt

  113. Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing

    Article • Development, June 2016, The Company of Biologists

    Professor Fiona M Watt

  114. Galectin-6 is a novel skin anti-microbial peptide that is modulated by the skin barrier and microbiome

    Article • Journal of Dermatological Science, June 2016, Elsevier

    Dr KEN NATSUGA, Professor Fiona M Watt

  115. β-Catenin Stabilization in Skin Fibroblasts Causes Fibrotic Lesions by Preventing Adipocyte Differentiation of the Reticular Dermis

    Article • Journal of Investigative Dermatology, June 2016, Elsevier

    Professor Fiona M Watt

  116. Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole-body energy expenditure

    Article • The Journal of Pathology, May 2016, Wiley

    Professor Fiona M Watt

  117. A high-content platform to characterise human induced pluripotent stem cell lines

    Article • Methods, March 2016, Elsevier

    Dr Davide Danovi, Professor Fiona M Watt

  118. Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages

    Article • Nature Communications, February 2016, Nature

    Professor Fiona M Watt

  119. Scalable topographies to support proliferation and Oct4 expression by human induced pluripotent stem cells

    Article • Scientific Reports, January 2016, Nature

    Professor Fiona M Watt

  120. Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-Induced Skin Carcinogenesis

    Article • Cancer Research, January 2016, American Association for Cancer Research (AACR)

    Professor Fiona M Watt

  121. Mimicking the topography of the epidermal–dermal interface with elastomer substrates

    Article • Integrative Biology, January 2016, Oxford University Press (OUP)

    Professor Fiona M Watt

  122. Increased Bacterial Load and Expression of Antimicrobial Peptides in Skin of Barrier-Deficient Mice with Reduced Cancer Susceptibility

    Article • Journal of Investigative Dermatology, January 2016, Elsevier

    Dr KEN NATSUGA, Professor Fiona M Watt

  123. Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity

    Article • Cell Reports, January 2016, Elsevier

    Professor Fiona M Watt

  124. Professor Sir Henry Harris (1925-2014)

    Article • Journal of Cell Science, December 2015, The Company of Biologists

    Professor Fiona M Watt

  125. Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation

    Article • Journal of Investigative Dermatology, December 2015, Elsevier

    Professor Fiona M Watt

  126. The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells

    Article • Journal of Investigative Dermatology, November 2015, Elsevier

    Professor Fiona M Watt

  127. Stem Cell Heterogeneity and Plasticity in Epithelia

    Article • Cell Stem Cell, May 2015, Elsevier

    Professor Fiona M Watt

  128. Recognizing the importance of new tools and resources for research

    Article • eLife, March 2015, eLife

    Professor Fiona M Watt

  129. Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for a randomized controlled trial

    Article • Trials, March 2015, Springer Science + Business Media

    Professor Fiona M Watt, Professor David Torgerson

  130. Seven Actionable Strategies for Advancing Women in Science, Engineering, and Medicine

    Article • Cell Stem Cell, March 2015, Elsevier

    Professor Fiona M Watt

  131. Understanding allergy and cancer risk: what are the barriers?

    Article • Nature Reviews Cancer, February 2015, Nature

    Professor Fiona M Watt

  132. Understanding fibroblast heterogeneity in the skin

    Article • Trends in Cell Biology, February 2015, Elsevier

    Professor Fiona M Watt

  133. Innate sensing of microbial products promotes wound-induced skin cancer

    Article • Nature Communications, January 2015, Nature

    Professor Fiona M Watt

  134. Mammalian skin cell biology: At the interface between laboratory and clinic

    Article • Science, November 2014, American Association for the Advancement of Science

    Professor Fiona M Watt

  135. Identification of Genes Important for Cutaneous Function Revealed by a Large Scale Reverse Genetic Screen in the Mouse

    Article • PLoS Genetics, October 2014, PLOS

    Professor Fiona M Watt

  136. BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous Gland Progenitor under Steady-State Conditions

    Article • Stem Cell Reports, October 2014, Elsevier

    Dr KEN NATSUGA, Professor Fiona M Watt

  137. Rewiring of an Epithelial Differentiation Factor, miR-203, to Inhibit Human Squamous Cell Carcinoma Metastasis

    Article • Cell Reports, October 2014, Elsevier

    Professor Fiona M Watt

  138. Defining dermal adipose tissue

    Article • Experimental Dermatology, September 2014, Wiley

    Professor Fiona M Watt

  139. Advancing research

    Article • eLife, August 2014, eLife

    Dr Detlef Weigel, Professor Fiona M Watt

  140. Modulating the stem cell niche for tissue regeneration

    Article • Nature Biotechnology, August 2014, Nature

    Professor Fiona M Watt

  141. Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin

    Article • Cold Spring Harbor Perspectives in Medicine, July 2014, Cold Spring Harbor Laboratory Press

    Professor Fiona M Watt

  142. Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility

    Article • eLife, May 2014, eLife

    Dr KEN NATSUGA, Professor Fiona M Watt

  143. Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen

    Article • Nature Communications, April 2014, Springer Science + Business Media

    Professor Fiona M Watt

  144. Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors

    Article • Proceedings of the National Academy of Sciences, March 2014, Proceedings of the National Academy of Sciences

    Dr KEN NATSUGA, Professor Fiona M Watt

  145. Distinct fibroblast lineages determine dermal architecture in skin development and repair

    Article • Nature, December 2013, Springer Science + Business Media

    Professor Fiona M Watt

  146. eLife and early career researchers

    Article • eLife, October 2013, eLife

    Dr Detlef Weigel, Professor Fiona M Watt

  147. A year in the life of eLife

    Article • eLife, October 2013, eLife

    Dr Detlef Weigel, Professor Fiona M Watt

  148. What is the point of large-scale collections of human induced pluripotent stem cells?

    Article • Nature Biotechnology, October 2013, Springer Science + Business Media

    Professor Fiona M Watt

  149. Sox2 modulates the function of two distinct cell lineages in mouse skin

    Article • Developmental Biology, October 2013, Elsevier

    Professor Fiona M Watt

  150. Downregulation of Keratin 76 Expression during Oral Carcinogenesis of Human, Hamster and Mouse

    Article • PLOS One, July 2013, PLOS

    Professor Fiona M Watt

  151. Role of the extracellular matrix in regulating stem cell fate

    Article • Nature Reviews Molecular Cell Biology, July 2013, Springer Science + Business Media

    Professor Fiona M Watt

  152. Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes

    Article • Cell, July 2013, Elsevier

    Professor Fiona M Watt

  153. Autoantibodies to Posttranslationally Modified Type II Collagen as Potential Biomarkers for Rheumatoid Arthritis

    Article • Arthritis & Rheumatism, July 2013, Wiley

    Professor Fiona M Watt

  154. The Interfollicular Epidermis of Adult Mouse Tail Comprises Two Distinct Cell Lineages that Are Differentially Regulated by Wnt, Edaradd, and Lrig1

    Article • Stem Cell Reports, June 2013, Elsevier

    Professor Fiona M Watt

  155. Decoupling geometrical and chemical cues directing epidermal stem cell fate on polymer brush-based cell micro-patterns

    Article • Integrative Biology, May 2013, Oxford University Press (OUP)

    Professor Fiona M Watt

  156. The eLife approach to peer review

    Article • eLife, April 2013, eLife

    Dr Detlef Weigel, Professor Fiona M Watt

  157. Single-cell gene expression profiling reveals functional heterogeneity of undifferentiated human epidermal cells

    Article • Development, March 2013, The Company of Biologists

    Professor Fiona M Watt

  158. What does it take to recruit and retain senior women faculty?

    Article • eLife, March 2013, eLife

    Professor Fiona M Watt

  159. LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development

    Article • The Journal of Pathology, February 2013, Wiley

    Dr Trevor A Graham, Professor Fiona M Watt

  160. Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair follicle stem cells

    Article • Proceedings of the National Academy of Sciences, February 2013, Proceedings of the National Academy of Sciences

    Professor Fiona M Watt, Floris Foijer

  161. c-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53 Axis

    Article • Cell Reports, February 2013, Elsevier

    Dr KEN NATSUGA, Professor Fiona M Watt

  162. Launching eLife, Part 2

    Article • eLife, December 2012, eLife

    Dr Detlef Weigel, Professor Fiona M Watt

  163. Launching eLife , Part 1

    Article • eLife, October 2012, eLife

    Dr Detlef Weigel, Professor Fiona M Watt

  164. Exons 5–15 of Kazrin Are Dispensable for Murine Epidermal Morphogenesis and Homeostasis

    Article • Journal of Investigative Dermatology, August 2012, Elsevier

    Professor Fiona M Watt

  165. Mimicking normal tissue architecture and perturbation in cancer with engineered micro-epidermis

    Article • Biomaterials, July 2012, Elsevier

    Professor Fiona M Watt

  166. Diverse epigenetic strategies interact to control epidermal differentiation

    Article • Nature Cell Biology, June 2012, Springer Science + Business Media

    Professor Fiona M Watt

  167. Polyclonal origin and hair induction ability of dermal papillae in neonatal and adult mouse back skin

    Article • Developmental Biology, June 2012, Elsevier

    Professor Fiona M Watt

  168. Carboxylate microsphere-induced cellular toxicity in human lung fibroblasts

    Article • Experimental Biology and Medicine, June 2012, SAGE Publications

    Professor Fiona M Watt

  169. Extracellular-matrix tethering regulates stem-cell fate

    Article • Nature Materials, May 2012, Springer Science + Business Media

    Dr Michelle L Oyen, Professor Fiona M Watt

  170. FRMD4A Upregulation in Human Squamous Cell Carcinoma Promotes Tumor Growth and Metastasis and Is Associated with Poor Prognosis

    Article • Cancer Research, May 2012, American Association for Cancer Research (AACR)

    Professor Fiona M Watt

  171. Efficient Differentiation of Embryonic Stem Cells into Mesodermal Precursors by BMP, Retinoic Acid and Notch Signalling

    Article • PLOS One, April 2012, PLOS

    Professor Fiona M Watt

  172. Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo

    Article • Journal of Investigative Dermatology, April 2012, Elsevier

    Professor Fiona M Watt

  173. Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling

    Article • Nature Cell Biology, March 2012, Springer Science + Business Media

    Professor Fiona M Watt

  174. Sin3a is essential for the genome integrity and viability of pluripotent cells

    Article • Developmental Biology, March 2012, Elsevier

    Professor Fiona M Watt

  175. Epithelial stem cells, wound healing and cancer

    Article • Nature Reviews Cancer, February 2012, Springer Science + Business Media

    Professor Fiona M Watt

  176. Single-cell electroporation using proton beam fabricated biochips

    Article • Biomedical Microdevices, February 2012, Springer Science + Business Media

    Professor Fiona M Watt

  177. β‐Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial–mesenchymal transition

    Article • The Journal of Pathology, January 2012, Wiley

    Professor Fiona M Watt

  178. A new technology for revealing the flow profile in integrated lab-on-a-chip

    Article • Medical Physics, January 2012, American Association of Physicists in Medicine (AAPM)

    Professor Fiona M Watt

  179. Lineage Tracing

    Article • Cell, January 2012, Elsevier

    Professor Fiona M Watt

  180. Epidermal Cadm1 Expression Promotes Autoimmune Alopecia via Enhanced T Cell Adhesion and Cytotoxicity

    Article • The Journal of Immunology, December 2011, The American Association of Immunologists

    Professor Fiona M Watt

  181. The RNA–Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to Differentiate

    Article • PLoS Genetics, December 2011, PLOS

    Professor Fiona M Watt

  182. Shape-Induced Terminal Differentiation of Human Epidermal Stem Cells Requires p38 and Is Regulated by Histone Acetylation

    Article • PLOS One, November 2011, PLOS

    Professor Fiona M Watt

  183. Stem cells: on the front line

    Article • Journal of Cell Science, November 2011, The Company of Biologists

    Professor Fiona M Watt

  184. High-throughput stem-cell niches

    Article • Nature Chemical Biology, October 2011, Springer Science + Business Media

    Professor Fiona M Watt

  185. Reprogramming adult dermis to a neonatal state through epidermal activation of  -catenin

    Article • Development, October 2011, The Company of Biologists

    Professor Fiona M Watt

  186. Upregulation of CD26 expression in epithelial cells and stromal cells during wound-induced skin tumour formation

    Article • Oncogene, July 2011, Springer Science + Business Media

    Professor Fiona M Watt

  187. Rac1 Deletion Causes Thymic Atrophy

    Article • PLOS One, April 2011, PLOS

    Professor Fiona M Watt

  188. Hair follicle dermal papilla cells at a glance

    Article • Journal of Cell Science, March 2011, The Company of Biologists

    Professor Fiona M Watt

  189. Cell-Extracellular Matrix Interactions in Normal and Diseased Skin

    Article • Cold Spring Harbor Perspectives in Biology, February 2011, Cold Spring Harbor Laboratory Press

    Professor Fiona M Watt

  190. The Basement Membrane of Hair Follicle Stem Cells Is a Muscle Cell Niche

    Article • Cell, February 2011, Elsevier

    Professor Fiona M Watt

  191. Cell Biology of Tissues and Tumors

    Article • Molecular Biology of the Cell, November 2010, American Society for Cell Biology (ASCB)

    Professor Fiona M Watt

  192. Xenopus Kazrin interacts with ARVCF-catenin, spectrin and p190B RhoGAP, and modulates RhoA activity and epithelial integrity

    Article • Journal of Cell Science, November 2010, The Company of Biologists

    Professor Fiona M Watt

  193. Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate

    Article • Proceedings of the National Academy of Sciences, November 2010, Proceedings of the National Academy of Sciences

    Professor Fiona M Watt

  194. Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest derivatives through upregulation of jagged 1

    Article • Development, October 2010, The Company of Biologists

    Professor Fiona M Watt

  195. Differential sensitivity of epidermal cell subpopulations to β-catenin-induced ectopic hair follicle formation

    Article • Developmental Biology, July 2010, Elsevier

    Professor Fiona M Watt

  196. Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions

    Article • Nature Cell Biology, June 2010, Springer Science + Business Media

    Professor Fiona M Watt

  197. Exploiting the superior protein resistance of polymer brushes to control single cell adhesion and polarisation at the micron scale

    Article • Biomaterials, June 2010, Elsevier

    Professor Fiona M Watt

  198. Assaying proliferation and differentiation capacity of stem cells using disaggregated adult mouse epidermis

    Article • Nature Protocols, April 2010, Springer Science + Business Media

    Professor Fiona M Watt

  199. 2009 Winner: Ravi Desai

    Article • Journal of Cell Science, March 2010, The Company of Biologists

    Professor Fiona M Watt

  200. Genomic gain of 5p15 leads to over-expression of Misu (NSUN2) in breast cancer

    Article • Cancer Letters, March 2010, Elsevier

    Professor Fiona M Watt

  201. Human Skin Aging Is Associated with Reduced Expression of the Stem Cell Markers β1 Integrin and MCSP

    Article • Journal of Investigative Dermatology, February 2010, Elsevier

    Professor Fiona M Watt

  202. JCS in 2010 - Ringing in the Changes

    Article • Journal of Cell Science, December 2009, The Company of Biologists

    Professor Fiona M Watt

  203. Dose and context dependent effects of Myc on epidermal stem cell proliferation and differentiation

    Article • EMBO Molecular Medicine, November 2009, EMBO

    Professor Fiona M Watt

  204. The therapeutic potential of stem cells

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, November 2009, Royal Society Publishing

    Professor Fiona M Watt

  205. KazrinE is a desmosome-associated liprin that colocalises with acetylated microtubules

    Article • Journal of Cell Science, October 2009, The Company of Biologists

    Professor Fiona M Watt

  206. Necl2 regulates epidermal adhesion and wound repair

    Article • Development, September 2009, The Company of Biologists

    Professor Fiona M Watt

  207. Epidermal stem cell diversity and quiescence

    Article • EMBO Molecular Medicine, August 2009, EMBO

    Professor Fiona M Watt

  208. Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis

    Article • Development, July 2009, The Company of Biologists

    Professor Fiona M Watt

  209. Stem cells are dispensable for lung homeostasis but restore airways after injury

    Article • Proceedings of the National Academy of Sciences, June 2009, Proceedings of the National Academy of Sciences

    Professor Fiona M Watt

  210. Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis

    Article • Cell Stem Cell, May 2009, Elsevier

    Professor Fiona M Watt

  211. Autophagy mediates the mitotic senescence transition

    Article • Genes & Development, April 2009, Cold Spring Harbor Laboratory Press

    Professor Fiona M Watt

  212. Balancing Work and Life: A Conversation with Fiona Watt

    Article • Stem Cells, February 2009, Wiley

    Professor Fiona M Watt

  213. An Activating  1 Integrin Mutation Increases the Conversion of Benign to Malignant Skin Tumors

    Article • Cancer Research, February 2009, American Association for Cancer Research (AACR)

    Professor Fiona M Watt

  214. Integrin Special Issue

    Article • Journal of Cell Science, December 2008, The Company of Biologists

    Professor Fiona M Watt

  215. Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplastic skin reveals roles for β-catenin and Notch signalling

    Article • Developmental Biology, December 2008, Elsevier

    Professor Fiona M Watt

  216. A stem cell gene expression profile of human squamous cell carcinomas

    Article • Cancer Letters, December 2008, Elsevier

    Professor Fiona M Watt

  217. Kazrin regulates keratinocyte cytoskeletal networks, intercellular junctions and differentiation

    Article • Journal of Cell Science, October 2008, The Company of Biologists

    Professor Fiona M Watt

  218. PI3-kinase-dependent activation of apoptotic machinery occurs on commitment of epidermal keratinocytes to terminal differentiation

    Article • BDJ, September 2008, Springer Science + Business Media

    Professor Fiona M Watt

  219. The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but not for Maintenance of the Epidermal Stem Cell Compartment

    Article • Journal of Investigative Dermatology, August 2008, Elsevier

    Professor Fiona M Watt

  220. KazrinA is required for axial elongation and epidermal integrity inXenopus tropicalis

    Article • Developmental Dynamics, June 2008, Wiley

    Professor Fiona M Watt

  221. Characterization of Bipotential Epidermal Progenitors Derived from Human Sebaceous Gland: Contrasting Roles of c-Myc and β-Catenin

    Article • Stem Cells, May 2008, Wiley

    Professor Fiona M Watt

  222. Epidermal stem cells are retained in vivo throughout skin aging

    Article • Aging Cell, April 2008, Wiley

    Professor Fiona M Watt

  223. Role of the Notch Ligand Delta1 in Embryonic and Adult Mouse Epidermis

    Article • Journal of Investigative Dermatology, April 2008, Elsevier

    Professor Fiona M Watt

  224. Epidermal Notch signalling: differentiation, cancer and adhesion

    Article • Current Opinion in Cell Biology, April 2008, Elsevier

    Professor Fiona M Watt

  225. MYC in mammalian epidermis: how can an oncogene stimulate differentiation?

    Article • Nature Reviews Cancer, March 2008, Springer Science + Business Media

    Professor Fiona M Watt

  226. Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFκB and cooperating with Stat3

    Article • Nature Cell Biology, January 2008, Springer Science + Business Media

    Professor Fiona M Watt

  227. The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis

    Article • PLOS One, January 2008, PLOS

    Professor Fiona M Watt

  228. Role of  -catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 2008, Cold Spring Harbor Laboratory Press

    Professor Fiona M Watt

  229. Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal barrier

    Article • Journal of Cell Biology, December 2007, Rockefeller University Press

    Professor Fiona M Watt

  230. Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell?

    Article • Cell Stem Cell, October 2007, Elsevier

    Professor Fiona M Watt

  231. Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced Differentiation

    Article • PLOS One, August 2007, PLOS

    Professor Fiona M Watt

  232. Syntenin mediates Delta1-induced cohesiveness of epidermal stem cells in culture

    Article • Journal of Cell Science, August 2007, The Company of Biologists

    Professor Fiona M Watt

  233. Epidermal Deletion of Rac1 Causes Stem Cell Depletion, Irrespective of whether Deletion Occurs during Embryogenesis or Adulthood

    Article • Journal of Investigative Dermatology, June 2007, Elsevier

    Professor Fiona M Watt

  234. Dual Role of Inactivating Lef1 Mutations in Epidermis: Tumor Promotion and Specification of Tumor Type

    Article • Cancer Research, April 2007, American Association for Cancer Research (AACR)

    Professor Fiona M Watt

  235. Activin A is an anticatabolic autocrine cytokine in articular cartilage whose production is controlled by fibroblast growth factor 2 and NF-κB

    Article • Arthritis & Rheumatism, January 2007, Wiley

    Professor Fiona M Watt

  236. Expression of Notch pathway genes in mammalian epidermis and modulation by β-Catenin

    Article • Developmental Dynamics, January 2007, Wiley

    Professor Fiona M Watt

  237. Identification of Novel Keratinocyte Differentiation Modulating Compounds by High-Throughput Screening

    Article • December 2006, SAGE Publications

    Professor Fiona M Watt

  238. Jagged 1 is a  -catenin target gene required for ectopic hair follicle formation in adult epidermis

    Article • Development, October 2006, The Company of Biologists

    Professor Fiona M Watt

  239. HAN11 binds mDia1 and controls GLI1 transcriptional activity

    Article • Journal of Dermatological Science, October 2006, Elsevier

    Professor Fiona M Watt

  240. Epidermal stem cells: an update

    Article • Current Opinion in Genetics & Development, October 2006, Elsevier

    Professor Fiona M Watt

  241. Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence

    Article • Proceedings of the National Academy of Sciences, August 2006, Proceedings of the National Academy of Sciences

    Professor Fiona M Watt

  242. The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes with characteristics of progenitor cells

    Article • Development, August 2006, The Company of Biologists

    Professor Fiona M Watt

  243. The RNA Methyltransferase Misu (NSun2) Mediates Myc-Induced Proliferation and Is Upregulated in Tumors

    Article • Current Biology, May 2006, Elsevier

    Professor Fiona M Watt

  244. Human sebaceous tumors harbor inactivating mutations in LEF1

    Article • Nature Medicine, March 2006, Springer Science + Business Media

    Professor Fiona M Watt

  245. Women in cell biology: how personal lives shape careers

    Article • Nature Reviews Molecular Cell Biology, March 2006, Springer Science + Business Media

    Professor Fiona M Watt

  246. Women in cell biology: getting to the top

    Article • Nature Reviews Molecular Cell Biology, March 2006, Springer Science + Business Media

    Professor Fiona M Watt

  247. New roles for integrins in squamous-cell carcinoma

    Article • Nature Reviews Cancer, February 2006, Springer Science + Business Media

    Professor Fiona M Watt

  248. Role of LIM Kinases in Normal and Psoriatic Human Epidermis

    Article • Molecular Biology of the Cell, January 2006, American Society for Cell Biology (ASCB)

    Professor Fiona M Watt

  249. Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1

    Article • Journal of Cell Biology, January 2006, Rockefeller University Press

    Professor Fiona M Watt

  250. Different Consequences of β1 Integrin Deletion in Neonatal and Adult Mouse Epidermis Reveal a Context-Dependent Role of Integrins in Regulating Proliferation, Differentiation, and Intercellular Communication

    Article • Journal of Investigative Dermatology, December 2005, Elsevier

    Professor Fiona M Watt

  251. Topo IIα reporter mice reveal proliferative regions in the epidermis and small intestine

    Article • FEBS Letters, November 2005, Wiley

    Professor Fiona M Watt

  252. Stem Cell Depletion Through Epidermal Deletion of Rac1

    Article • Science, August 2005, American Association for the Advancement of Science

    Professor Fiona M Watt

  253. β-Catenin and Hedgehog Signal Strength Can Specify Number and Location of Hair Follicles in Adult Epidermis without Recruitment of Bulge Stem Cells

    Article • Developmental Cell, July 2005, Elsevier

    Professor Fiona M Watt

  254. Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs

    Article • Nature Genetics, April 2005, Springer Science + Business Media

    Professor Fiona M Watt

  255. Fran Balkwill

    Article • Journal of Cell Science, April 2005, The Company of Biologists

    Professor Fiona M Watt

  256. Suprabasal α5β1 integrin expression stimulates formation of epidermal squamous cell carcinomas without disrupting TGFβ signaling or inducing spindle cell tumors

    Article • Molecular Carcinogenesis, January 2005, Wiley

    Professor Fiona M Watt

  257. Unexpected Hedgehog–Wnt interactions in epithelial differentiation

    Article • Trends in Molecular Medicine, December 2004, Elsevier

    Professor Fiona M Watt

  258. Elaine Fuchs

    Article • Journal of Cell Science, October 2004, The Company of Biologists

    Professor Fiona M Watt

  259. Sequence variation in the I-like domain of the β1 integrin subunit in human oral squamous cell carcinomas

    Article • Cancer Letters, September 2004, Elsevier

    Professor Fiona M Watt

  260. Expression of Activated MEK1 in Differentiating Epidermal Cells Is Sufficient to Generate Hyperproliferative and Inflammatory Skin Lesions

    Article • Journal of Investigative Dermatology, September 2004, Elsevier

    Professor Fiona M Watt

  261. Epidermal Label-Retaining Cells: Background and Recent Applications

    Article • Journal of Investigative Dermatology Symposium Proceedings, September 2004, Elsevier

    Professor Fiona M Watt

  262. Kazrin, a novel periplakin-interacting protein associated with desmosomes and the keratinocyte plasma membrane

    Article • Journal of Cell Biology, August 2004, Rockefeller University Press

    Professor Fiona M Watt

  263. Transient activation of FOXN1 in keratinocytes induces a transcriptional programme that promotes terminal differentiation: contrasting roles of FOXN1 and Akt

    Article • Journal of Cell Science, August 2004, The Company of Biologists

    Professor Fiona M Watt

  264. Switch from αvβ5 to αvβ6 integrin expression protects squamous cell carcinomas from anoikis

    Article • Journal of Cell Biology, August 2004, Rockefeller University Press

    Professor Fiona M Watt

  265. Transient activation of  -catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours

    Article • Development, April 2004, The Company of Biologists

    Professor Fiona M Watt

  266. Non-profit publishing: open access and the end of copyright transfer

    Article • Journal of Cell Science, January 2004, The Company of Biologists

    Professor Fiona M Watt

  267. Keratinocyte Differentiation Is Regulated by the Rho and ROCK Signaling Pathway

    Article • Current Biology, December 2003, Elsevier

    Professor Fiona M Watt

  268. Role of melanoma chondroitin sulphate proteoglycan in patterning stem cells in human interfollicular epidermis

    Article • Development, October 2003, The Company of Biologists

    Professor Fiona M Watt

  269. Indian hedgehog and β-catenin signaling: Role in the sebaceous lineage of normal and neoplastic mammalian epidermis

    Article • Proceedings of the National Academy of Sciences, September 2003, Proceedings of the National Academy of Sciences

    Professor Fiona M Watt

  270. Suprabasal  6 4 integrin expression in epidermis results in enhanced tumourigenesis and disruption of TGF  signalling

    Article • Journal of Cell Science, September 2003, The Company of Biologists

    Professor Fiona M Watt

  271. Manipulation of stem cell proliferation and lineage commitment: visualisation of label-retaining cells in wholemounts of mouse epidermis

    Article • Development, August 2003, The Company of Biologists

    Professor Fiona M Watt

  272. Regulation of keratinocyte shape, migration and wound epithelialization by IGF-1- and EGF-dependent signalling pathways

    Article • Journal of Cell Science, August 2003, The Company of Biologists

    Professor Fiona M Watt

  273. Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment

    Article • Development, June 2003, The Company of Biologists

    Professor Fiona M Watt

  274. Contribution of stem cells and differentiated cells to epidermal tumours

    Article • Nature Reviews Cancer, June 2003, Springer Science + Business Media

    Professor Fiona M Watt

  275. Q & A

    Article • Current Biology, April 2003, Elsevier

    Professor Fiona M Watt

  276. Regulation of Interleukin-1  Expression by Integrins and Epidermal Growth Factor Receptor in Keratinocytes from a Mouse Model of Inflammatory Skin Disease

    Article • Journal of Biological Chemistry, March 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Fiona M Watt

  277. A tumor-associated β1 integrin mutation that abrogates epithelial differentiation control

    Article • Journal of Cell Biology, February 2003, Rockefeller University Press

    Professor Fiona M Watt

  278. Interaction of periplakin and envoplakin with intermediate filaments

    Article • Journal of Cell Science, December 2002, The Company of Biologists

    Professor Fiona M Watt

  279. NEW EMBO MEMBER'S REVIEW: Role of integrins in regulating epidermal adhesion, growth and differentiation

    Article • The EMBO Journal, August 2002, Wiley

    Professor Fiona M Watt

  280. The stem cell compartment in human interfollicular epidermis

    Article • Journal of Dermatological Science, April 2002, Elsevier

    Professor Fiona M Watt

  281. Designer skin: lineage commitment in postnatal epidermis

    Article • Trends in Cell Biology, April 2002, Elsevier

    Professor Fiona M Watt

  282. Gene Targeting of Envoplakin, a Cytoskeletal Linker Protein and Precursor of the Epidermal Cornified Envelope

    Article • Molecular and Cellular Biology, October 2001, ASM Journals

    Professor Fiona M Watt

  283. Delta regulates keratinocyte spreading and motility independently of differentiation

    Article • Mechanisms of Development, September 2001, Elsevier

    Professor Fiona M Watt

  284. Cutting Edge: Amelioration of Kidney Disease in a Transgenic Mouse Model of Lupus Nephritis by Administration of the Caspase Inhibitor Carbobenzoxy-Valyl-Alanyl-Aspartyl-( -o-methyl)-Fluoromethylketone

    Article • The Journal of Immunology, September 2001, The American Association of Immunologists

    Professor Fiona M Watt

  285. A role for mitogen-activated protein kinase activation by integrins in the pathogenesis of psoriasis

    Article • Journal of Clinical Investigation, August 2001, American Society for Clinical Investigation

    Professor Fiona M Watt

  286. Stem cell fate and patterning in mammalian epidermis

    Article • Current Opinion in Genetics & Development, August 2001, Elsevier

    Professor Fiona M Watt

  287. Paraneoplastic Pemphigus Sera React Strongly with Multiple Epitopes on the Various Regions of Envoplakin and Periplakin, Except for the C-Terminal Homologous Domain of Periplakin

    Article • Journal of Investigative Dermatology, April 2001, Elsevier

    Professor Fiona M Watt

  288. c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny

    Article • Current Biology, April 2001, Elsevier

    Professor Fiona M Watt

  289. Dermal Fibroblast-Derived Growth Factors Restore the Ability of β1 Integrin-Deficient Embryonal Stem Cells to Differentiate into Keratinocytes

    Article • Developmental Biology, March 2001, Elsevier

    Professor Fiona M Watt

  290. p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes

    Article • EMBO Reports, February 2001, EMBO

    Professor Fiona M Watt

  291. Epithelial Cell Differentiation Pathways in the Human Prostate: Identification of Intermediate Phenotypes by Keratin Expression

    Article • Journal of Histochemistry & Cytochemistry, February 2001, SAGE Publications

    Professor Fiona M Watt

  292. PA-FABP, a novel marker of human epidermal transit amplifying cells revealed by 2D protein gel electrophoresis and cDNA array hybridisation

    Article • FEBS Letters, December 2000, Wiley

    Professor Fiona M Watt

  293. Expression of involucrin in normal, hyperproliferative and neoplastic mouse keratinocytes

    Article • Experimental Dermatology, December 2000, Wiley

    Professor Fiona M Watt

  294. Epidermal Stem Cells as Targets for Gene Transfer

    Article • Human Gene Therapy, November 2000, Mary Ann Liebert Inc

    Professor Fiona M Watt

  295. Asymmetric stem-cell divisions define the architecture of human oesophageal epithelium

    Article • Current Biology, November 2000, Elsevier

    Professor Fiona M Watt

  296. Subcellular Distribution of Envoplakin and Periplakin

    Article • Journal of Cell Biology, October 2000, Rockefeller University Press

    Professor Fiona M Watt

  297. Proliferative Heterogeneity in the Human Prostate: Evidence for Epithelial Stem Cells

    Article • Laboratory Investigation, August 2000, Springer Science + Business Media

    Professor Fiona M Watt

  298. The EGF Receptor Provides an Essential Survival Signal for SOS-Dependent Skin Tumor Development

    Article • Cell, July 2000, Elsevier

    Professor Fiona M Watt

  299. ?1B integrin subunit contains a double lysine motif that can cause accumulation within the endoplasmic reticulum

    Article • Journal of Cellular Biochemistry, July 2000, Wiley

    Professor Fiona M Watt

  300. The α2 and α5 integrin genes: identification of transcription factors that regulate promoter activity in epidermal keratinocytes

    Article • FEBS Letters, May 2000, Wiley

    Professor Fiona M Watt

  301. Stimulation of human epidermal differentiation by Delta–Notch signalling at the boundaries of stem-cell clusters

    Article • Current Biology, May 2000, Elsevier

    Professor Fiona M Watt

  302. Structure and Regulation of the Envoplakin Gene

    Article • Journal of Biological Chemistry, March 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Fiona M Watt, Professor Christiana Ruhrberg

  303. Out of Eden: Stem Cells and Their Niches

    Article • Science, February 2000, American Association for the Advancement of Science

    Professor Fiona M Watt

  304. beta 1 Integrins Regulate Keratinocyte Adhesion and Differentiation by Distinct Mechanisms

    Article • Molecular Biology of the Cell, February 2000, American Society for Cell Biology (ASCB)

    Professor Fiona M Watt

  305. Envoplakin, a Possible Candidate Gene for Focal NEPPK/Esophageal Cancer (TOC): The Integration of Genetic and Physical Maps of the TOC Region on 17q25

    Article • Genomics, July 1999, Elsevier

    Professor Fiona M Watt, Professor Christiana Ruhrberg

  306. Signaling via β1 integrins and mitogen-activated protein kinase determines human epidermal stem cell fate in vitro

    Article • Proceedings of the National Academy of Sciences, June 1999, Proceedings of the National Academy of Sciences

    Professor Fiona M Watt

  307. Evidence that apoptosis and terminal differentiation of epidermal keratinocytes are distinct processes

    Article • Experimental Dermatology, February 1999, Wiley

    Professor Fiona M Watt

  308. Analysis of cultured keratinocytes from a transgenic mouse model of psoriasis: effects of suprabasal integrin expression on keratinocyte adhesion, proliferation and terminal differentiation

    Article • Experimental Dermatology, February 1999, Wiley

    Professor Fiona M Watt

  309. Lack of intrinsic polarity in the ligandbinding ability of keratinocyte ?1integrins

    Article • Experimental Dermatology, December 1998, Wiley

    Professor Fiona M Watt

  310. Envoplakin and Periplakin are Components of the Paraneoplastic Pemphigus Antigen Complex

    Article • Journal of Investigative Dermatology, December 1998, Elsevier

    Professor Fiona M Watt, Professor Christiana Ruhrberg

  311. Role of integrins in mouse eyelid development: studies in normal embryos and embryos in which there is a failure of eyelid fusion

    Article • Mechanisms of Development, November 1998, Elsevier

    Professor Fiona M Watt

  312. Comparison of integrin, cadherin, and catenin expression in squamous cell carcinomas of the oral cavity

    Article • The Journal of Pathology, September 1998, Wiley

    Professor Fiona M Watt

  313. Optimised retroviral infection of human epidermal keratinocytes: long-term expression of transduced integrin gene following grafting on to SCID mice

    Article • Gene Therapy, July 1998, Springer Science + Business Media

    Professor Fiona M Watt

  314. Epidermal stem cells: markers, patterning and the control of stem cell fate

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, June 1998, Royal Society Publishing

    Professor Fiona M Watt

  315. The Periplakin Gene Maps to 16p13.3 in Human and 16A–B1 in Mouse

    Article • Genomics, April 1998, Elsevier

    Professor Fiona M Watt, Professor Christiana Ruhrberg

  316. Periplakin, a Novel Component of Cornified Envelopes and Desmosomes That Belongs to the Plakin Family and Forms Complexes with Envoplakin

    Article • Journal of Cell Biology, December 1997, Rockefeller University Press

    Professor Fiona M Watt, Professor Christiana Ruhrberg

  317. Antinuclear Autoantibodies and Lupus Nephritis in Transgenic Mice Expressing Interferon   in the Epidermis

    Article • Journal of Experimental Medicine, November 1997, Rockefeller University Press

    Professor Fiona M Watt

  318. c-Myc promotes differentiation of human epidermal stem cells

    Article • Genes & Development, November 1997, Cold Spring Harbor Laboratory Press

    Professor Fiona M Watt

  319. Correlation between hyperproliferation and suprabasal integrin expression in human epidermis reconstituted in culture

    Article • Experimental Dermatology, October 1997, Wiley

    Professor Fiona M Watt

  320. The plakin family: versatile organizers of cytoskeletal architecture

    Article • Current Opinion in Genetics & Development, June 1997, Elsevier

    Professor Fiona M Watt, Professor Christiana Ruhrberg

  321. The Epidermal Stem Cell Compartment: Variation in Expression Levels of E–Cadherin and Catenins Within the Basal Layer of Human Epidermis

    Article • Journal of Histochemistry & Cytochemistry, June 1997, SAGE Publications

    Professor Fiona M Watt

  322. Transgenic Mice Expressing IFN-γ in the Epidermis Have Eczema, Hair Hypopigmentation, and Hair Loss

    Article • Journal of Investigative Dermatology, April 1997, Elsevier

    Professor Fiona M Watt

  323. Changes in the expression of alphav integrins in oral squamous cell carcinomas

    Article • Journal of Oral Pathology and Medicine, February 1997, Wiley

    Professor Fiona M Watt

  324. Chromosomal Localisation of the Human Envoplakin Gene (EVPL) to the Region of the Tylosis Oesophageal Cancer Gene (TOCG) on 17q25

    Article • Genomics, November 1996, Elsevier

    Professor Fiona M Watt

  325. Differentiation of Embryonal Stem Cells into Keratinocytes: Comparison of Wild-Type and β1Integrin-Deficient Cells

    Article • Developmental Biology, October 1996, Elsevier

    Professor Fiona M Watt

  326. Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin

    Article • Journal of Cell Biology, August 1996, Rockefeller University Press

    Professor Fiona M Watt, Professor Christiana Ruhrberg

  327. Altered expression of CD44 isoforms in squamous-cell carcinomas and cell lines derived from them

    Article • International Journal of Cancer, May 1996, Wiley

    Professor Fiona M Watt

  328. Immunoelectron microscopic analysis of cornified cell envelope formation in normal and psoriatic epidermis.

    Article • Journal of Histochemistry & Cytochemistry, February 1996, SAGE Publications

    Professor Fiona M Watt

  329. Suprabasal integrin expression in the epidermis of transgenic mice results in developmental defects and a phenotype resembling psoriasis

    Article • Cell, December 1995, Elsevier

    Professor Fiona M Watt

  330. The 5? noncoding region of the mouse involucrin gene: comparison with the human gene and genes encoding other cornified envelope precursors

    Article • Mammalian Genome, September 1995, Springer Science + Business Media

    Professor Fiona M Watt

  331. Regulation of cell surface beta 1 integrin levels during keratinocyte terminal differentiation

    Article • Journal of Cell Biology, March 1995, Rockefeller University Press

    Professor Fiona M Watt

  332. Integrin Expression by Human Epidermal Keratinocytes Can Be Modulated by Interferon-γ, Transforming Growth Factor-β, Tumor Necrosis Factor-α, and Culture on a Dermal Equivalent

    Article • Journal of Investigative Dermatology, February 1995, Elsevier

    Professor Fiona M Watt

  333. Stem cell patterning and fate in human epidermis

    Article • Cell, January 1995, Elsevier

    Professor Fiona M Watt

  334. Cell Adhesion: Fibronectin and integrin knockouts come unstuck

    Article • Current Biology, March 1994, Elsevier

    Professor Fiona M Watt

  335. Studies with cultured human epidermal keratinocytes: Potential relevance to corneal wound healing

    Article • Eye, March 1994, Springer Science + Business Media

    Professor Fiona M Watt

  336. Evidence that cadherins play a role in the downregulation of integrin expression that occurs during keratinocyte terminal differentiation

    Article • Journal of Cell Biology, February 1994, Rockefeller University Press

    Professor Fiona M Watt

  337. Loss of α6 and β4 integrin subunits coincides with loss of basement membrane components in oral squamous cell carcinomas

    Article • The Journal of Pathology, November 1993, Wiley

    Professor Fiona M Watt

  338. Changes in the Distribution of Actin-Associated Proteins During Epidermal Wound Healing

    Article • Journal of Investigative Dermatology, June 1993, Elsevier

    Professor Fiona M Watt

  339. Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression

    Article • Cell, May 1993, Elsevier

    Professor Fiona M Watt

  340. Towards gene therapy for haemophilia B using primary human keratinocytes

    Article • Nature Genetics, February 1993, Springer Science + Business Media

    Professor Fiona M Watt

  341. Integrin expression in normal, hyperplastic, dysplastic, and malignant oral epithelium

    Article • The Journal of Pathology, February 1993, Wiley

    Professor Fiona M Watt

  342. Comparison of integrin expression and terminal differentiation capacity in cell lines derived from oral squamous cell carcinomas

    Article • Carcinogenesis, January 1993, Oxford University Press (OUP)

    Professor Fiona M Watt

  343. Characterisation of Eight Monoclonal Antibodies to Involucrin

    Article • Hybridoma, June 1992, Mary Ann Liebert Inc

    Professor Fiona M Watt

  344. Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis.

    Article • Journal of Clinical Investigation, June 1992, American Society for Clinical Investigation

    Professor Fiona M Watt

  345. Kalinin, epiligrin and GB3 antigen: kalinepiligrinin-3?

    Article • Current Biology, February 1992, Elsevier

    Professor Fiona M Watt

  346. Expression of beta 1, beta 3, beta 4, and beta 5 integrins by human epidermal keratinocytes and non-differentiating keratinocytes

    Article • Journal of Cell Biology, November 1991, Rockefeller University Press

    Professor Fiona M Watt

  347. Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is related to the cadherin family of cell adhesion molecules.

    Article • Proceedings of the National Academy of Sciences, June 1991, Proceedings of the National Academy of Sciences

    Professor Fiona M Watt

  348. Expression of E-cadherin, P-cadherin and involucrin by normal and neoplastic keratinocytes in culture

    Article • Carcinogenesis, January 1991, Oxford University Press (OUP)

    Professor Fiona M Watt

  349. Two strains of human keratinocytes transfected with HPV16 DNA: comparison with the normal parental cells

    Article • Carcinogenesis, January 1991, Oxford University Press (OUP)

    Professor Fiona M Watt

  350. Changes in keratinocyte adhesion during terminal differentiation: Reduction in fibronectin binding precedes α5β1 integrin loss from the cell surface

    Article • Cell, October 1990, Elsevier

    Professor Fiona M Watt

  351. Characterisation of the peanut lectin-binding glycoproteins of human epidermal keratinocytes

    Article • Differentiation, April 1990, Elsevier

    Professor Fiona M Watt

  352. DNA amplification is rare in normal human cells.

    Article • Proceedings of the National Academy of Sciences, March 1990, Proceedings of the National Academy of Sciences

    Professor Fiona M Watt

  353. Terminal differentiation of epidermal keratinocytes

    Article • Current Opinion in Cell Biology, December 1989, Elsevier

    Professor Fiona M Watt

  354. Fibronectin inhibits the terminal differentiation of human keratinocytes

    Article • Nature, July 1989, Springer Science + Business Media

    Professor Fiona M Watt

  355. Pentapeptide inhibitor of epidermal mitosis: production and responsiveness in cultures of normal, transformed and neoplastic human keratinocytes

    Article • Carcinogenesis, January 1989, Oxford University Press (OUP)

    Professor Fiona M Watt

  356. An unusual strain of human keratinocytes which do not stratify or undergo terminal differentiation in culture

    Article • Journal of Cell Biology, November 1988, Rockefeller University Press

    Professor Fiona M Watt

  357. Influence of cytochalasin d-induced changes in cell shape on proteoglycan synthesis by cultured articular chondrocytes

    Article • Experimental Cell Research, October 1988, Elsevier

    Professor Fiona M Watt

  358. The peanut lectin-binding glycoproteins of human epidermal keratinocytes

    Article • Experimental Cell Research, August 1988, Elsevier

    Professor Fiona M Watt

  359. Cell shape controls terminal differentiation of human epidermal keratinocytes.

    Article • Proceedings of the National Academy of Sciences, August 1988, Proceedings of the National Academy of Sciences

    Professor Fiona M Watt

  360. Prolonged expression of differentiated phenotype by chondrocytes cultured at low density on a composite substrate of collagen and agarose that restricts cell spreading

    Article • Differentiation, July 1988, Elsevier

    Professor Fiona M Watt

  361. The epidermal keratinocyte

    Article • BioEssays, May 1988, Wiley

    Professor Fiona M Watt

  362. A Model for in Vitro Studies of Epidermal Homeostasis: Proliferation and Involucrin Synthesis by Cultured Human Keratinocytes During Recovery After Stripping Off the Suprabasal Layers

    Article • Journal of Investigative Dermatology, May 1988, Elsevier

    Professor Fiona M Watt

  363. Patterns of junctional communication in skin: Studies on cultured keratinocytes

    Article • Experimental Cell Research, December 1987, Elsevier

    Professor Fiona M Watt

  364. Measurement of the Rate of Epidermal Terminal Differentiation: Expression of Involucrin by S-Phase Keratinocytes in Culture and in Psoriatic Plaques

    Article • Journal of Investigative Dermatology, October 1987, Elsevier

    Professor Fiona M Watt

  365. Calcium-induced changes in cytoskeleton and motility of cultured human keratinocytes

    Article • Experimental Cell Research, September 1987, Elsevier

    Professor Fiona M Watt

  366. Effect of growth environment on spatial expression of involucrin by human epidermal keratinocytes

    Article • Archives of Dermatological Research, June 1987, Springer Science + Business Media

    Professor Fiona M Watt

  367. Two subpopulations of differentiated chondrocytes identified with a monoclonal antibody to keratan sulfate

    Article • Journal of Cell Biology, July 1985, Rockefeller University Press

    Professor Fiona M Watt

  368. Biosynthesis of EGF receptor, transferrin receptor and colligin by cultured human keratinocytes and the effect of retinoic acid

    Article • Experimental Cell Research, July 1985, Elsevier

    Professor Fiona M Watt

  369. Biochemical specificity of Xenopus notochord

    Article • Differentiation, July 1985, Elsevier

    Professor Fiona M Watt

  370. Calcium-induced reorganization of desmosomal components in cultured human keratinocytes

    Article • Journal of Cell Biology, December 1984, Rockefeller University Press

    Professor Fiona M Watt

  371. Selective migration of terminally differentiating cells from the basal layer of cultured human epidermis

    Article • Journal of Cell Biology, January 1984, Rockefeller University Press

    Professor Fiona M Watt

  372. Involucrin and Other Markers of Keratinocyte Terminal Differentiation.

    Article • Journal of Investigative Dermatology, July 1983, Elsevier

    Professor Fiona M Watt

  373. Keratinocyte culture club

    Article • Nature, December 1982, Springer Science + Business Media

    Professor Fiona M Watt

  374. Stratification and terminal differentiation of cultured epidermal cells

    Article • Nature, February 1982, Springer Science + Business Media

    Professor Fiona M Watt

  375. Involucrin synthesis is correlated with cell size in human epidermal cultures

    Article • Journal of Cell Biology, September 1981, Rockefeller University Press

    Professor Fiona M Watt