Professor Fiona M Watt
King's College London
Professor, Health Sciences
United Kingdom
My co-authors include
Piero Carninci
Dr Davide Danovi
Floris Foijer
My Publications
Human epidermal stem cell differentiation is modulated by specific lipid subspecies
Proceedings of the National Academy of Sciences
August 2020
Regulation of ERK basal and pulsatile activity control proliferation and exit from the ...
Proceedings of the National Academy of Sciences
July 2020
CD147 (BSG) but not ACE2 expression is detectable in vascular endothelial cells within ...
May 2020
ERK basal and pulsatile activity are differentially regulated in mammalian epidermis to...
April 2020
Map clusters of diseases to tackle multimorbidity
Nature
March 2020
What is AI? Applications of artificial intelligence to dermatology
British Journal of Dermatology
January 2020
Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Muc...
Cell Stem Cell
December 2019
NOTCH1 signaling in oral squamous cell carcinoma via a TEL2/SERPINE1 axis
Oncotarget
October 2019
High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gast...
PLoS Biology
October 2019
Delta-like 1-mediated cis-inhibition of Jagged1/2 signalling inhibits differentiation o...
Scientific Reports
July 2019
The role of keratins in modulating carcinogenesis via communication with cells of the i...
Cell Stress
April 2019
Mutant Lef1 controls Gata6 in sebaceous gland development and cancer
The EMBO Journal
March 2019
Genome-wide association study in frontal fibrosing alopecia identifies four susceptibil...
Nature Communications
March 2019
Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human i...
Cell Reports
February 2019
Patterning of human epidermal stem cells on undulating elastomer substrates reflects di...
Acta Biomaterialia
January 2019
Bench to bedside: Current advances in regenerative medicine
Current Opinion in Cell Biology
December 2018
Micro-scaled topographies direct differentiation of human epidermal stem cells
Acta Biomaterialia
December 2018
High-throughput micro-patterning platform reveals Nodal-dependent dissection of peri-ga...
November 2018
Hair follicle epidermal stem cells define a niche for tactile sensation
eLife
October 2018
Lrig1 marks a population of gastric epithelial cells capable of long-term tissue mainte...
Scientific Reports
October 2018
Dynamic culture substrates that mimic the topography of the epidermal-dermal junction
Tissue Engineering Part A
October 2018
The reward of great collaborations
Nature Cell Biology
August 2018
Immunomodulatory role of Keratin 76 in oral and gastric cancer
Nature Communications
August 2018
Fibroblast state switching orchestrates dermal maturation and wound healing
Molecular Systems Biology
August 2018
Loxl2 is dispensable for dermal development, homeostasis and tumour stroma formation
PLoS ONE
June 2018
Hair Follicle Epidermal Stem Cells Define a Niche for Tactile Sensation
June 2018
Defining Adult Stem Cells by Function, not by Phenotype
Annual Review of Biochemistry
June 2018
1351 Investigation of the molecular identity of the junctional zone in human
Journal of Investigative Dermatology
May 2018
1354 Spatial and single-cell transcriptional profiling identifies functionally distinct...
Journal of Investigative Dermatology
May 2018
Skin Cell Heterogeneity in Development, Wound Healing, and Cancer
Trends in Cell Biology
May 2018
Diverse mechanisms for endogenous regeneration and repair in mammalian organs
Nature
May 2018
IMMUNOMODULATORY ROLE OF KERATIN 76 IN ORAL AND GASTRIC CANCER
April 2018
Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Huma...
Journal of Investigative Dermatology
April 2018
An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis
Nature
April 2018
(More) women in science
Nature Reviews Molecular Cell Biology
March 2018
Myosin 10 is involved in murine pigmentation
Experimental Dermatology
March 2018
Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate i...
January 2018
Fibroblast heterogeneity: implications for human disease
Journal of Clinical Investigation
January 2018
Homeostasis, regeneration and tumour formation in the mammalian epidermis
The International Journal of Developmental Biology
January 2018
The Human Cell Atlas
eLife
December 2017
Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation
Science Translational Medicine
November 2017
Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Foll...
Journal of Investigative Dermatology
November 2017
Spatial constraints govern competition of mutant clones in human epidermis
Nature Communications
October 2017
A protein phosphatase network controls the temporal and spatial dynamics of differentia...
eLife
October 2017
085 Type XVII collagen suppresses interfollicular epidermal proliferation in neonatal a...
Journal of Investigative Dermatology
October 2017
554 Dissecting fibroblast heterogeneity in skin cancer
Journal of Investigative Dermatology
October 2017
Type XVII collagen coordinates proliferation in the interfollicular epidermis
eLife
July 2017
ERK MAPK activation bursts and propagation in adult and embryonic mouse skin
Mechanisms of Development
July 2017
Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate i...
June 2017
Erratum: Corrigendum: Common genetic variation drives molecular heterogeneity in human ...
Nature
June 2017
Wounding induces dedifferentiation of epidermal Gata6+ cells and acquisition of stem ce...
Nature Cell Biology
May 2017
Common genetic variation drives molecular heterogeneity in human iPSCs
Nature
May 2017
Repeal and Replace: Adipocyte Regeneration in Wound Repair
Cell Stem Cell
April 2017
A genome-wide screen identifies YAP/WBP2 interplay conferring growth advantage on human...
Nature Communications
March 2017
Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the P...
American Journal of Transplantation
February 2017
Reply to Chi et al.
Journal of Investigative Dermatology
January 2017
Live image tricky cells and integrate the data with datasets without the dimension of time
SLAS DISCOVERY Advancing the Science of Drug Discovery
October 2016
Integrative genomic and functional analysis of human oral squamous cell carcinoma cell ...
Cancer Letters
September 2016
Engineered Microenvironments to Direct Epidermal Stem Cell Behavior at Single-Cell Reso...
Developmental Cell
September 2016
Pelota Regulates Epidermal Differentiation by Modulating BMP and PI3K/AKT Signaling Pat...
Journal of Investigative Dermatology
August 2016
CIRM and UKRMP: Different Ways to Invest in Regenerative Medicine
Cell Stem Cell
July 2016
Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regener...
Development
June 2016
Galectin-6 is a novel skin anti-microbial peptide that is modulated by the skin barrier...
Journal of Dermatological Science
June 2016
β-Catenin Stabilization in Skin Fibroblasts Causes Fibrotic Lesions by Preventing Adipo...
Journal of Investigative Dermatology
June 2016
Alkaline ceramidase 1 is essential for mammalian skin homeostasis and regulating whole-...
The Journal of Pathology
May 2016
A high-content platform to characterise human induced pluripotent stem cell lines
Methods
March 2016
Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct...
Nature Communications
February 2016
Scalable topographies to support proliferation and Oct4 expression by human induced plu...
Scientific Reports
January 2016
Macrophage Infiltration and Alternative Activation during Wound Healing Promote MEK1-In...
Cancer Research
January 2016
Mimicking the topography of the epidermal–dermal interface with elastomer substrates
Integrative Biology
January 2016
Increased Bacterial Load and Expression of Antimicrobial Peptides in Skin of Barrier-De...
Journal of Investigative Dermatology
January 2016
Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Repr...
Cell Reports
January 2016
Professor Sir Henry Harris (1925-2014)
Journal of Cell Science
December 2015
Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing an...
Journal of Investigative Dermatology
December 2015
The Androgen Receptor Antagonizes Wnt/β-Catenin Signaling in Epidermal Stem Cells
Journal of Investigative Dermatology
November 2015
Stem Cell Heterogeneity and Plasticity in Epithelia
Cell Stem Cell
May 2015
Recognizing the importance of new tools and resources for research
eLife
March 2015
Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii tri...
Current Controlled Trials in Cardiovascular Medicine
March 2015
Seven Actionable Strategies for Advancing Women in Science, Engineering, and Medicine
Cell Stem Cell
March 2015
Understanding allergy and cancer risk: what are the barriers?
Nature Reviews Drug Discovery
February 2015
Understanding fibroblast heterogeneity in the skin
Trends in Cell Biology
February 2015
Innate sensing of microbial products promotes wound-induced skin cancer
Nature Communications
January 2015
Mammalian skin cell biology: At the interface between laboratory and clinic
Science
November 2014
Identification of Genes Important for Cutaneous Function Revealed by a Large Scale Reve...
PLoS Genetics
October 2014
BLIMP1 Is Required for Postnatal Epidermal Homeostasis but Does Not Define a Sebaceous ...
Stem Cell Reports
October 2014
Rewiring of an Epithelial Differentiation Factor, miR-203, to Inhibit Human Squamous Ce...
Cell Reports
October 2014
Defining dermal adipose tissue
Experimental Dermatology
September 2014
Advancing research
eLife
August 2014
Modulating the stem cell niche for tissue regeneration
Nature Biotechnology
August 2014
Markers of Epidermal Stem Cell Subpopulations in Adult Mammalian Skin
Cold Spring Harbor Perspectives in Medicine
July 2014
Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility
eLife
May 2014
Novel skin phenotypes revealed by a genome-wide mouse reverse genetic screen
Nature Communications
April 2014
Epidermal Wnt/ -catenin signaling regulates adipocyte differentiation via secretion of ...
Proceedings of the National Academy of Sciences
March 2014
Distinct fibroblast lineages determine dermal architecture in skin development and repair
Nature
December 2013
eLife and early career researchers
eLife
October 2013
A year in the life of eLife
eLife
October 2013
What is the point of large-scale collections of human induced pluripotent stem cells?
Nature Biotechnology
October 2013
Sox2 modulates the function of two distinct cell lineages in mouse skin
Developmental Biology
October 2013
Downregulation of Keratin 76 Expression during Oral Carcinogenesis of Human, Hamster an...
PLoS ONE
July 2013
Role of the extracellular matrix in regulating stem cell fate
Nature Reviews Molecular Cell Biology
July 2013
Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles fo...
Cell
July 2013
Autoantibodies to Posttranslationally Modified Type II Collagen as Potential Biomarkers...
Arthritis & Rheumatism
July 2013
The Interfollicular Epidermis of Adult Mouse Tail Comprises Two Distinct Cell Lineages ...
Stem Cell Reports
June 2013
Decoupling geometrical and chemical cues directing epidermal stem cell fate on polymer ...
Integrative Biology
May 2013
The eLife approach to peer review
eLife
April 2013
Single-cell gene expression profiling reveals functional heterogeneity of undifferentia...
Development
March 2013
What does it take to recruit and retain senior women faculty?
eLife
March 2013
LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis ...
The Journal of Pathology
February 2013
Spindle checkpoint deficiency is tolerated by murine epidermal cells but not hair folli...
Proceedings of the National Academy of Sciences
February 2013
c-MYC-Induced Sebaceous Gland Differentiation Is Controlled by an Androgen Receptor/p53...
Cell Reports
February 2013
Launching eLife, Part 2
eLife
December 2012
Launching eLife , Part 1
eLife
October 2012
Exons 5–15 of Kazrin Are Dispensable for Murine Epidermal Morphogenesis and Homeostasis
Journal of Investigative Dermatology
August 2012
Mimicking normal tissue architecture and perturbation in cancer with engineered micro-e...
Biomaterials
July 2012
Diverse epigenetic strategies interact to control epidermal differentiation
Nature Cell Biology
June 2012
Polyclonal origin and hair induction ability of dermal papillae in neonatal and adult m...
Developmental Biology
June 2012
Carboxylate microsphere-induced cellular toxicity in human lung fibroblasts
Experimental Biology and Medicine
June 2012
Extracellular-matrix tethering regulates stem-cell fate
Nature Materials
May 2012
FRMD4A Upregulation in Human Squamous Cell Carcinoma Promotes Tumor Growth and Metastas...
Cancer Research
May 2012
Efficient Differentiation of Embryonic Stem Cells into Mesodermal Precursors by BMP, Re...
PLoS ONE
April 2012
Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences betwee...
Journal of Investigative Dermatology
April 2012
Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling
Nature Cell Biology
March 2012
Sin3a is essential for the genome integrity and viability of pluripotent cells
Developmental Biology
March 2012
Epithelial stem cells, wound healing and cancer
Nature Reviews Cancer
February 2012
Single-cell electroporation using proton beam fabricated biochips
Biomedical Microdevices
February 2012
β‐Catenin determines upper airway progenitor cell fate and preinvasive squamous lung ca...
The Journal of Pathology
January 2012
A new technology for revealing the flow profile in integrated lab-on-a-chip
Medical Physics
January 2012
Lineage Tracing
Cell
January 2012
Epidermal Cadm1 Expression Promotes Autoimmune Alopecia via Enhanced T Cell Adhesion an...
The Journal of Immunology
December 2011
The RNA–Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to Differentiate
PLoS Genetics
December 2011
Shape-Induced Terminal Differentiation of Human Epidermal Stem Cells Requires p38 and I...
PLoS ONE
November 2011
Stem cells: on the front line
Journal of Cell Science
November 2011
High-throughput stem-cell niches
Nature Methods
October 2011
Reprogramming adult dermis to a neonatal state through epidermal activation of -catenin
Development
October 2011
Upregulation of CD26 expression in epithelial cells and stromal cells during wound-indu...
Oncogene
July 2011
Rac1 Deletion Causes Thymic Atrophy
PLoS ONE
April 2011
Hair follicle dermal papilla cells at a glance
Journal of Cell Science
March 2011
Cell-Extracellular Matrix Interactions in Normal and Diseased Skin
Cold Spring Harbor Perspectives in Biology
February 2011
The Basement Membrane of Hair Follicle Stem Cells Is a Muscle Cell Niche
Cell
February 2011
Cell Biology of Tissues and Tumors
Molecular Biology of the Cell
November 2010
Xenopus Kazrin interacts with ARVCF-catenin, spectrin and p190B RhoGAP, and modulates R...
Journal of Cell Science
November 2010
Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrate
Proceedings of the National Academy of Sciences
November 2010
Adult epidermal Notch activity induces dermal accumulation of T cells and neural crest ...
Development
October 2010
Differential sensitivity of epidermal cell subpopulations to β-catenin-induced ectopic ...
Developmental Biology
July 2010
Actin and serum response factor transduce physical cues from the microenvironment to re...
Nature Cell Biology
June 2010
Exploiting the superior protein resistance of polymer brushes to control single cell ad...
Biomaterials
June 2010
Assaying proliferation and differentiation capacity of stem cells using disaggregated a...
Nature Protocols
April 2010
2009 Winner: Ravi Desai
Journal of Cell Science
March 2010
Genomic gain of 5p15 leads to over-expression of Misu (NSUN2) in breast cancer
Cancer Letters
March 2010
Human Skin Aging Is Associated with Reduced Expression of the Stem Cell Markers β1 Inte...
Journal of Investigative Dermatology
February 2010
JCS in 2010 - Ringing in the Changes
Journal of Cell Science
December 2009
Dose and context dependent effects of Myc on epidermal stem cell proliferation and diff...
EMBO Molecular Medicine
November 2009
The therapeutic potential of stem cells
Philosophical Transactions of the Royal Society B Biological Sciences
November 2009
KazrinE is a desmosome-associated liprin that colocalises with acetylated microtubules
Journal of Cell Science
October 2009
Necl2 regulates epidermal adhesion and wound repair
Development
September 2009
Epidermal stem cell diversity and quiescence
EMBO Molecular Medicine
August 2009
Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis
Development
July 2009
Stem cells are dispensable for lung homeostasis but restore airways after injury
Proceedings of the National Academy of Sciences
May 2009
Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epide...
Cell Stem Cell
May 2009
Autophagy mediates the mitotic senescence transition
Genes & Development
April 2009
Balancing Work and Life: A Conversation with Fiona Watt
The International Journal Of Cell Cloning
February 2009
An Activating 1 Integrin Mutation Increases the Conversion of Benign to Malignant Skin...
Cancer Research
February 2009
Integrin Special Issue
Journal of Cell Science
December 2008
Dynamic regulation of retinoic acid-binding proteins in developing, adult and neoplasti...
Developmental Biology
December 2008
A stem cell gene expression profile of human squamous cell carcinomas
Cancer Letters
December 2008
Kazrin regulates keratinocyte cytoskeletal networks, intercellular junctions and differ...
Journal of Cell Science
October 2008
PI3-kinase-dependent activation of apoptotic machinery occurs on commitment of epiderma...
Cell Research
September 2008
The Vitamin D Receptor Is Required for Mouse Hair Cycle Progression but not for Mainten...
Journal of Investigative Dermatology
August 2008
KazrinA is required for axial elongation and epidermal integrity inXenopus tropicalis
Developmental Dynamics
June 2008
Characterization of Bipotential Epidermal Progenitors Derived from Human Sebaceous Glan...
The International Journal Of Cell Cloning
May 2008
Epidermal stem cells are retained in vivo throughout skin aging
Aging Cell
April 2008
Role of the Notch Ligand Delta1 in Embryonic and Adult Mouse Epidermis
Journal of Investigative Dermatology
April 2008
Epidermal Notch signalling: differentiation, cancer and adhesion
Current Opinion in Cell Biology
April 2008
MYC in mammalian epidermis: how can an oncogene stimulate differentiation?
Nature Reviews Cancer
March 2008
Nanog maintains pluripotency of mouse embryonic stem cells by inhibiting NFκB and coope...
Nature Cell Biology
January 2008
The Vitamin D Receptor Is a Wnt Effector that Controls Hair Follicle Differentiation an...
PLoS ONE
January 2008
Role of -catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer
Cold Spring Harbor Symposia on Quantitative Biology
January 2008
Mice deficient in involucrin, envoplakin, and periplakin have a defective epidermal bar...
The Journal of Cell Biology
December 2007
Sic Transit Gloria: Farewell to the Epidermal Transit Amplifying Cell?
Cell Stem Cell
October 2007
Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by My...
PLoS ONE
August 2007
Syntenin mediates Delta1-induced cohesiveness of epidermal stem cells in culture
Journal of Cell Science
August 2007
Epidermal Deletion of Rac1 Causes Stem Cell Depletion, Irrespective of whether Deletion...
Journal of Investigative Dermatology
June 2007
Dual Role of Inactivating Lef1 Mutations in Epidermis: Tumor Promotion and Specificatio...
Cancer Research
April 2007
Activin A is an anticatabolic autocrine cytokine in articular cartilage whose productio...
Arthritis & Rheumatism
January 2007
Expression of Notch pathway genes in mammalian epidermis and modulation by β-Catenin
Developmental Dynamics
January 2007
Identification of Novel Keratinocyte Differentiation Modulating Compounds by High-Throu...
December 2006
Jagged 1 is a -catenin target gene required for ectopic hair follicle formation in adu...
Development
October 2006
HAN11 binds mDia1 and controls GLI1 transcriptional activity
Journal of Dermatological Science
October 2006
Epidermal stem cells: an update
Current Opinion in Genetics & Development
October 2006
The cell-surface marker MTS24 identifies a novel population of follicular keratinocytes...
Development
August 2006
Single-cell expression profiling of human epidermal stem and transit-amplifying cells: ...
Proceedings of the National Academy of Sciences
July 2006
The RNA Methyltransferase Misu (NSun2) Mediates Myc-Induced Proliferation and Is Upregu...
Current Biology
May 2006
Human sebaceous tumors harbor inactivating mutations in LEF1
Nature Medicine
March 2006
Women in cell biology: how personal lives shape careers
Nature Reviews Molecular Cell Biology
March 2006
Women in cell biology: getting to the top
Nature Reviews Molecular Cell Biology
March 2006
New roles for integrins in squamous-cell carcinoma
Nature Reviews Cancer
February 2006
Role of LIM Kinases in Normal and Psoriatic Human Epidermis
Molecular Biology of the Cell
January 2006
Myc regulates keratinocyte adhesion and differentiation via complex formation with Miz1
The Journal of Cell Biology
January 2006
Different Consequences of β1 Integrin Deletion in Neonatal and Adult Mouse Epidermis Re...
Journal of Investigative Dermatology
December 2005
Topo IIα reporter mice reveal proliferative regions in the epidermis and small intestine
FEBS Letters
November 2005
Stem Cell Depletion Through Epidermal Deletion of Rac1
Science
August 2005
β-Catenin and Hedgehog Signal Strength Can Specify Number and Location of Hair Follicle...
Developmental Cell
July 2005
Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs
Nature Genetics
April 2005
Fran Balkwill
Journal of Cell Science
April 2005
Suprabasal α5β1 integrin expression stimulates formation of epidermal squamous cell car...
Molecular Carcinogenesis
January 2005
Unexpected Hedgehog–Wnt interactions in epithelial differentiation
Trends in Molecular Medicine
December 2004
Elaine Fuchs
Journal of Cell Science
October 2004
Sequence variation in the I-like domain of the β1 integrin subunit in human oral squamo...
Cancer Letters
September 2004
Expression of Activated MEK1 in Differentiating Epidermal Cells Is Sufficient to Genera...
Journal of Investigative Dermatology
September 2004
Epidermal Label-Retaining Cells: Background and Recent Applications
Journal of Investigative Dermatology Symposium Proceedings
September 2004
Kazrin, a novel periplakin-interacting protein associated with desmosomes and the kerat...
The Journal of Cell Biology
August 2004
Transient activation of FOXN1 in keratinocytes induces a transcriptional programme that...
Journal of Cell Science
August 2004
Switch from αvβ5 to αvβ6 integrin expression protects squamous cell carcinomas from ano...
The Journal of Cell Biology
August 2004
Transient activation of -catenin signalling in adult mouse epidermis is sufficient to ...
Development
April 2004
Non-profit publishing: open access and the end of copyright transfer
Journal of Cell Science
January 2004
Keratinocyte Differentiation Is Regulated by the Rho and ROCK Signaling Pathway
Current Biology
December 2003
Role of melanoma chondroitin sulphate proteoglycan in patterning stem cells in human in...
Development
October 2003
Suprabasal 6 4 integrin expression in epidermis results in enhanced tumourigenesis and...
Journal of Cell Science
September 2003
Manipulation of stem cell proliferation and lineage commitment: visualisation of label-...
Development
August 2003
Indian hedgehog and -catenin signaling: Role in the sebaceous lineage of normal and ne...
Proceedings of the National Academy of Sciences
August 2003
Regulation of keratinocyte shape, migration and wound epithelialization by IGF-1- and E...
Journal of Cell Science
August 2003
Evidence that Myc activation depletes the epidermal stem cell compartment by modulating...
Development
June 2003
Contribution of stem cells and differentiated cells to epidermal tumours
Nature Reviews Cancer
June 2003
Q & A
Current Biology
April 2003
Regulation of Interleukin-1 Expression by Integrins and Epidermal Growth Factor Recept...
Journal of Biological Chemistry
March 2003
A tumor-associated β1 integrin mutation that abrogates epithelial differentiation control
The Journal of Cell Biology
February 2003
Interaction of periplakin and envoplakin with intermediate filaments
Journal of Cell Science
December 2002
NEW EMBO MEMBER'S REVIEW: Role of integrins in regulating epidermal adhesion, growth an...
The EMBO Journal
August 2002
The stem cell compartment in human interfollicular epidermis
Journal of Dermatological Science
April 2002
Designer skin: lineage commitment in postnatal epidermis
Trends in Cell Biology
April 2002
Gene Targeting of Envoplakin, a Cytoskeletal Linker Protein and Precursor of the Epider...
Molecular and Cellular Biology
October 2001
Delta regulates keratinocyte spreading and motility independently of differentiation
Mechanisms of Development
September 2001
Cutting Edge: Amelioration of Kidney Disease in a Transgenic Mouse Model of Lupus Nephr...
The Journal of Immunology
September 2001
A role for mitogen-activated protein kinase activation by integrins in the pathogenesis...
Journal of Clinical Investigation
August 2001
Stem cell fate and patterning in mammalian epidermis
Current Opinion in Genetics & Development
August 2001
Paraneoplastic Pemphigus Sera React Strongly with Multiple Epitopes on the Various Regi...
Journal of Investigative Dermatology
April 2001
c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells an...
Current Biology
April 2001
Dermal Fibroblast-Derived Growth Factors Restore the Ability of β1 Integrin-Deficient E...
Developmental Biology
March 2001
p19ARF-independent induction of p53 and cell cycle arrest by Raf in murine keratinocytes
EMBO Reports
February 2001
Epithelial Cell Differentiation Pathways in the Human Prostate: Identification of Inter...
Journal of Histochemistry & Cytochemistry
February 2001
PA-FABP, a novel marker of human epidermal transit amplifying cells revealed by 2D prot...
FEBS Letters
December 2000
Expression of involucrin in normal, hyperproliferative and neoplastic mouse keratinocytes
Experimental Dermatology
December 2000
Epidermal Stem Cells as Targets for Gene Transfer
Human Gene Therapy
November 2000
Asymmetric stem-cell divisions define the architecture of human oesophageal epithelium
Current Biology
November 2000
Subcellular Distribution of Envoplakin and Periplakin
The Journal of Cell Biology
October 2000
Proliferative Heterogeneity in the Human Prostate: Evidence for Epithelial Stem Cells
Laboratory Investigation
August 2000
The EGF Receptor Provides an Essential Survival Signal for SOS-Dependent Skin Tumor Dev...
Cell
July 2000
?1B integrin subunit contains a double lysine motif that can cause accumulation within ...
Journal of Cellular Biochemistry
July 2000
The α2 and α5 integrin genes: identification of transcription factors that regulate pro...
FEBS Letters
May 2000
Stimulation of human epidermal differentiation by Delta–Notch signalling at the boundar...
Current Biology
May 2000
Structure and Regulation of the Envoplakin Gene
Journal of Biological Chemistry
March 2000
Out of Eden: Stem Cells and Their Niches
Science
February 2000
beta 1 Integrins Regulate Keratinocyte Adhesion and Differentiation by Distinct Mechanisms
Molecular Biology of the Cell
February 2000
Envoplakin, a Possible Candidate Gene for Focal NEPPK/Esophageal Cancer (TOC): The Inte...
Genomics
July 1999
Signaling via 1 integrins and mitogen-activated protein kinase determines human epider...
Proceedings of the National Academy of Sciences
June 1999
Evidence that apoptosis and terminal differentiation of epidermal keratinocytes are dis...
Experimental Dermatology
February 1999
Analysis of cultured keratinocytes from a transgenic mouse model of psoriasis: effects ...
Experimental Dermatology
February 1999
Lack of intrinsic polarity in the ligandbinding ability of keratinocyte ?1integrins
Experimental Dermatology
December 1998
Envoplakin and Periplakin are Components of the Paraneoplastic Pemphigus Antigen Complex
Journal of Investigative Dermatology
December 1998
Role of integrins in mouse eyelid development: studies in normal embryos and embryos in...
Mechanisms of Development
November 1998
Comparison of integrin, cadherin, and catenin expression in squamous cell carcinomas of...
The Journal of Pathology
September 1998
Optimised retroviral infection of human epidermal keratinocytes: long-term expression o...
Gene Therapy
July 1998
Epidermal stem cells: markers, patterning and the control of stem cell fate
Philosophical Transactions of the Royal Society B Biological Sciences
June 1998
The Periplakin Gene Maps to 16p13.3 in Human and 16A–B1 in Mouse
Genomics
April 1998
Periplakin, a Novel Component of Cornified Envelopes and Desmosomes That Belongs to the...
The Journal of Cell Biology
December 1997
Antinuclear Autoantibodies and Lupus Nephritis in Transgenic Mice Expressing Interferon...
The Journal of Experimental Medicine
November 1997
c-Myc promotes differentiation of human epidermal stem cells
Genes & Development
November 1997
Correlation between hyperproliferation and suprabasal integrin expression in human epid...
Experimental Dermatology
October 1997
The plakin family: versatile organizers of cytoskeletal architecture
Current Opinion in Genetics & Development
June 1997
The Epidermal Stem Cell Compartment: Variation in Expression Levels of E–Cadherin and C...
Journal of Histochemistry & Cytochemistry
June 1997
Transgenic Mice Expressing IFN-γ in the Epidermis Have Eczema, Hair Hypopigmentation, a...
Journal of Investigative Dermatology
April 1997
Changes in the expression of alphav integrins in oral squamous cell carcinomas
Journal of Oral Pathology and Medicine
February 1997
Chromosomal Localisation of the Human Envoplakin Gene (EVPL) to the Region of the Tylos...
Genomics
November 1996
Differentiation of Embryonal Stem Cells into Keratinocytes: Comparison of Wild-Type and...
Developmental Biology
October 1996
Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin
The Journal of Cell Biology
August 1996
Altered expression of CD44 isoforms in squamous-cell carcinomas and cell lines derived ...
International Journal of Cancer
May 1996
Immunoelectron microscopic analysis of cornified cell envelope formation in normal and ...
Journal of Histochemistry & Cytochemistry
February 1996
Suprabasal integrin expression in the epidermis of transgenic mice results in developme...
Cell
December 1995
The 5? noncoding region of the mouse involucrin gene: comparison with the human gene an...
Mammalian Genome
September 1995
Regulation of cell surface beta 1 integrin levels during keratinocyte terminal differen...
The Journal of Cell Biology
March 1995
Integrin Expression by Human Epidermal Keratinocytes Can Be Modulated by Interferon-γ, ...
Journal of Investigative Dermatology
February 1995
Stem cell patterning and fate in human epidermis
Cell
January 1995
Cell Adhesion: Fibronectin and integrin knockouts come unstuck
Current Biology
March 1994
Studies with cultured human epidermal keratinocytes: Potential relevance to corneal wou...
Eye
March 1994
Evidence that cadherins play a role in the downregulation of integrin expression that o...
The Journal of Cell Biology
February 1994
Loss of α6 and β4 integrin subunits coincides with loss of basement membrane components...
The Journal of Pathology
November 1993
Changes in the Distribution of Actin-Associated Proteins During Epidermal Wound Healing
Journal of Investigative Dermatology
June 1993
Separation of human epidermal stem cells from transit amplifying cells on the basis of ...
Cell
May 1993
Towards gene therapy for haemophilia B using primary human keratinocytes
Nature Genetics
February 1993
Integrin expression in normal, hyperplastic, dysplastic, and malignant oral epithelium
The Journal of Pathology
February 1993
Comparison of integrin expression and terminal differentiation capacity in cell lines d...
Carcinogenesis
January 1993
Characterisation of Eight Monoclonal Antibodies to Involucrin
Hybridoma
June 1992
Aberrant integrin expression during epidermal wound healing and in psoriatic epidermis.
Journal of Clinical Investigation
June 1992
Kalinin, epiligrin and GB3 antigen: kalinepiligrinin-3?
Current Biology
February 1992
Expression of beta 1, beta 3, beta 4, and beta 5 integrins by human epidermal keratinoc...
The Journal of Cell Biology
November 1991
Desmosomal glycoprotein DGI, a component of intercellular desmosome junctions, is relat...
Proceedings of the National Academy of Sciences
June 1991
Expression of E-cadherin, P-cadherin and involucrin by normal and neoplastic keratinocy...
Carcinogenesis
January 1991
Two strains of human keratinocytes transfected with HPV16 DNA: comparison with the norm...
Carcinogenesis
January 1991
Changes in keratinocyte adhesion during terminal differentiation: Reduction in fibronec...
Cell
October 1990
Characterisation of the peanut lectin-binding glycoproteins of human epidermal keratino...
Differentiation
April 1990
DNA amplification is rare in normal human cells.
Proceedings of the National Academy of Sciences
March 1990
Terminal differentiation of epidermal keratinocytes
Current Opinion in Cell Biology
December 1989
Fibronectin inhibits the terminal differentiation of human keratinocytes
Nature
July 1989
Pentapeptide inhibitor of epidermal mitosis: production and responsiveness in cultures ...
Carcinogenesis
January 1989
An unusual strain of human keratinocytes which do not stratify or undergo terminal diff...
The Journal of Cell Biology
November 1988
Influence of cytochalasin d-induced changes in cell shape on proteoglycan synthesis by ...
Experimental Cell Research
October 1988
The peanut lectin-binding glycoproteins of human epidermal keratinocytes
Experimental Cell Research
August 1988
Cell shape controls terminal differentiation of human epidermal keratinocytes.
Proceedings of the National Academy of Sciences
August 1988
Prolonged expression of differentiated phenotype by chondrocytes cultured at low densit...
Differentiation
July 1988
The epidermal keratinocyte
BioEssays
May 1988
A Model for in Vitro Studies of Epidermal Homeostasis: Proliferation and Involucrin Syn...
Journal of Investigative Dermatology
May 1988
Patterns of junctional communication in skin: Studies on cultured keratinocytes
Experimental Cell Research
December 1987
Measurement of the Rate of Epidermal Terminal Differentiation: Expression of Involucrin...
Journal of Investigative Dermatology
October 1987
Calcium-induced changes in cytoskeleton and motility of cultured human keratinocytes
Experimental Cell Research
September 1987
Effect of growth environment on spatial expression of involucrin by human epidermal ker...
Archives of Dermatological Research
June 1987
Two subpopulations of differentiated chondrocytes identified with a monoclonal antibody...
The Journal of Cell Biology
July 1985
Biosynthesis of EGF receptor, transferrin receptor and colligin by cultured human kerat...
Experimental Cell Research
July 1985
Biochemical specificity of Xenopus notochord
Differentiation
July 1985
Calcium-induced reorganization of desmosomal components in cultured human keratinocytes
The Journal of Cell Biology
December 1984
Selective migration of terminally differentiating cells from the basal layer of culture...
The Journal of Cell Biology
January 1984
Involucrin and Other Markers of Keratinocyte Terminal Differentiation.
Journal of Investigative Dermatology
July 1983
Keratinocyte culture club
Nature
December 1982
Stratification and terminal differentiation of cultured epidermal cells
Nature
February 1982
Involucrin synthesis is correlated with cell size in human epidermal cultures
The Journal of Cell Biology
September 1981
