All Stories

  1. Gene mutant dosage is associated with prognosis and metastatic tropism in 60,000 clinical cancer samples

    Article • Nature Genetics, July 2026, Springer Science + Business Media

    Dr Trevor A Graham

  2. PHYFUM: Phylogenetic Reconstruction of Normal and Pre-malignant Tissue Evolution Using Fluctuating Methylation

    Article • May 2026, openRxiv

    Dr Trevor A Graham

  3. Inference of Cancer Drug Cross Resistance Using Only Single-Drug Exposure Data

    Article • March 2026, openRxiv

    Dr Trevor A Graham

  4. Classpose: foundation model-driven whole slide image-scale cell phenotyping in H&E

    Article • December 2025, openRxiv

    Dr Trevor A Graham

  5. Data from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  6. Figure 1 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  7. Figure 2 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  8. Figure 3 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  9. Figure 4 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  10. Figure 5 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  11. Figure 6 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  12. Figure 7 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  13. Figure 8 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  14. Supplementary Figure 1 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  15. Supplementary Figure 2 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  16. Supplementary Figure 3 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  17. Supplementary Figure 4 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  18. Supplementary Figure 5 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  19. Supplementary Figure 6 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  20. Supplementary Figure 7 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  21. Supplementary Figure 8 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  22. Supplementary Figure 9 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  23. Supplementary Table 1 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  24. Supplementary Table 2 from Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • September 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  25. Mathematical modelling of cancer cell evolution and plasticity

    Article • Current Opinion in Cell Biology, August 2025, Elsevier

    Dr Trevor A Graham

  26. Quantitative measurement of phenotype dynamics during cancer drug resistance evolution using genetic barcoding

    Article • Nature Communications, June 2025, Springer Science + Business Media

    Dr Trevor A Graham

  27. Adaptive Therapy Exploits Fitness Deficits in Chemotherapy-Resistant Ovarian Cancer to Achieve Long-Term Tumor Control

    Article • Cancer Research, April 2025, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  28. Quantitative measurement of phenotype dynamics during cancer drug resistance evolution using genetic barcoding

    Article • March 2025, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  29. Deep Learning for Biomarker Discovery in Cancer Genomes

    Article • January 2025, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  30. Phenotypic noise and plasticity in cancer evolution

    Article • Trends in Cell Biology, June 2024, Elsevier

    Dr Trevor A Graham

  31. Gene mutant dosage determines prognosis and metastatic tropism in 60,000 clinical cancer samples

    Article • May 2024, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  32. Contribution of pks+ E. coli mutations to colorectal carcinogenesis

    Article • Nature Communications, November 2023, Springer Science + Business Media

    Dr Trevor A Graham

  33. Adaptive therapy achieves long-term control of chemotherapy resistance in high grade ovarian cancer

    Article • July 2023, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  34. Bridging clinic and wildlife care with AI-powered pan-species computational pathology

    Article • Nature Communications, April 2023, Springer Science + Business Media

    Dr Trevor A Graham

  35. First passage time analysis of spatial mutation patterns reveals sub-clonal evolutionary dynamics in colorectal cancer

    Article • PLoS Computational Biology, March 2023, PLOS

    Dr Trevor A Graham

  36. Whole genome sequencing of 2,023 colorectal cancers reveals mutational landscapes, new driver genes and immune interactions

    Article • November 2022, Springer Science + Business Media

    Dr Trevor A Graham

  37. Cell Competition in Carcinogenesis

    Article • Cancer Research, October 2022, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  38. The mutational signatures of formalin fixation on the human genome

    Article • Nature Communications, September 2022, Springer Science + Business Media

    Dr Trevor A Graham

  39. Lineage tracing in human tissues

    Article • The Journal of Pathology, May 2022, Wiley

    Dr Trevor A Graham

  40. AI-powered pan-species computational pathology: bridging clinic and wildlife care

    Article • March 2022, Springer Science + Business Media

    Dr Trevor A Graham

  41. CNETML: Maximum likelihood inference of phylogeny from copy number profiles of spatio-temporal samples

    Article • March 2022, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  42. AI-powered pan-species computational pathology: bridging clinic and wildlife care

    Article • March 2022, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  43. First passage time analysis of spatial mutation patterns reveals evolutionary dynamics of pre-existing resistance in colorectal cancer

    Article • February 2022, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  44. Evolutionary dynamics in Barrett oesophagus: implications for surveillance, risk stratification and therapy

    Article • Nature Reviews Gastroenterology & Hepatology, November 2021, Springer Science + Business Media

    Dr Trevor A Graham

  45. LiquidCNA: Tracking subclonal evolution from longitudinal liquid biopsies using somatic copy number alterations

    Article • iScience, August 2021, Elsevier

    Dr Trevor A Graham

  46. Predicting Colorectal Cancer Occurrence in IBD

    Article • Cancers, June 2021, MDPI AG

    Dr Trevor A Graham

  47. The mutational signatures of formalin fixation on the human genome

    Article • March 2021, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  48. LiquidCNA: tracking subclonal evolution from longitudinal liquid biopsies using somatic copy number alterations

    Article • January 2021, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  49. Genomic landscape and clonal architecture of mouse oral squamous cell carcinomas dictate tumour ecology

    Article • Nature Communications, November 2020, Springer Science + Business Media

    Professor Fiona M Watt, Dr Trevor A Graham

  50. Platinum resistance induces diverse evolutionary trajectories in high grade serous ovarian cancer

    Article • July 2020, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  51. Navigating the path to distant metastasis

    Article • Nature Genetics, July 2020, Springer Science + Business Media

    Dr Trevor A Graham

  52. Author Correction: The effects of mutational processes and selection on driver mutations across cancer types

    Article • Nature Communications, April 2020, Springer Science + Business Media

    Dr Trevor A Graham

  53. Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios

    Article • eLife, March 2020, eLife

    Dr Trevor A Graham

  54. Measuring single cell divisions in human tissues from multi-region sequencing data

    Article • Nature Communications, February 2020, Springer Science + Business Media

    Dr Trevor A Graham

  55. A novel use of random priming-based single-strand library preparation for whole genome sequencing of formalin-fixed paraffin-embedded tissue samples

    Article • NAR Genomics and Bioinformatics, December 2019, Oxford University Press (OUP)

    Dr Trevor A Graham

  56. Author Correction: Resolving genetic heterogeneity in cancer

    Article • Nature Reviews Genetics, October 2019, Springer Science + Business Media

    Dr Trevor A Graham

  57. Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data

    Article • PLoS Computational Biology, July 2019, PLOS

    Dr Trevor A Graham

  58. Measuring the distribution of fitness effects in somatic evolution by combining clonal dynamics with dN/dS ratios

    Article • June 2019, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  59. Niche engineering drives early passage through an immune bottleneck in progression to colorectal cancer

    Article • May 2019, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  60. Resolving genetic heterogeneity in cancer

    Article • Nature Reviews Genetics, March 2019, Springer Science + Business Media

    Dr Trevor A Graham

  61. Model-based tumor subclonal reconstruction

    Article • March 2019, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  62. Crypt fusion as a homeostatic mechanism in the human colon

    Article • Gut, March 2019, BMJ

    Biancastella Cereser, Dr Trevor A Graham

  63. Measuring single cell divisions in human cancers from multi-region sequencing data

    Article • February 2019, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  64. Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data

    Article • February 2019, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  65. Evolutionary dynamics of neoantigens in growing tumours

    Article • January 2019, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  66. NeoPredPipe: High-Throughput Neoantigen Prediction and Recognition Potential Pipeline

    Article • December 2018, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  67. Reply to ‘Currently available bulk sequencing data do not necessarily support a model of neutral tumor evolution’

    Article • Nature Genetics, October 2018, Springer Science + Business Media

    Dr Trevor A Graham

  68. Reply to ‘Revisiting signatures of neutral tumor evolution in the light of complexity of cancer genomic data’

    Article • Nature Genetics, September 2018, Springer Science + Business Media

    Dr Trevor A Graham

  69. Detecting repeated cancer evolution from multi-region tumor sequencing data

    Article • Nature Chemical Biology, August 2018, Springer Science + Business Media

    Dr Trevor A Graham

  70. The evolutionary landscape of colorectal tumorigenesis

    Article • Nature Ecology & Evolution, August 2018, Springer Science + Business Media

    Dr Trevor A Graham

  71. Author Correction: Quantification of subclonal selection in cancer from bulk sequencing data

    Article • Nature Genetics, July 2018, Springer Science + Business Media

    Dr Trevor A Graham

  72. Evolutionary history of human colitis-associated colorectal cancer

    Article • Gut, July 2018, BMJ

    Dr Trevor A Graham

  73. Quantification of subclonal selection in cancer from bulk sequencing data

    Article • Nature Genetics, May 2018, Springer Science + Business Media

    Dr Trevor A Graham

  74. The effects of mutational processes and selection on driver mutations across cancer types

    Article • Nature Communications, May 2018, Springer Science + Business Media

    Dr Trevor A Graham

  75. Reply: Neutral tumor evolution?

    Article • March 2018, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  76. Evolution of Barrett’s esophagus through space and time at single-crypt and whole-biopsy levels

    Article • Nature Communications, February 2018, Nature

    Dr Trevor A Graham

  77. Robust RNA-based in situ mutation detection delineates colorectal cancer subclonal evolution

    Article • Nature Communications, December 2017, Springer Science + Business Media

    Dr Trevor A Graham

  78. Cumulative burden of inflammation predicts colorectal neoplasia risk in ulcerative colitis: a large single-centre study

    Article • Gut, November 2017, BMJ

    Dr Trevor A Graham

  79. Insights Into the Pathophysiology of Esophageal Adenocarcinoma

    Article • Gastroenterology, October 2017, Elsevier

    Dr Trevor A Graham

  80. Reply: Uncertainties in tumor allele frequencies limit power to infer evolutionary pressures

    Article • Nature Genetics, August 2017, Nature

    Dr Trevor A Graham

  81. Detecting repeated cancer evolution in human tumours from multi-region sequencing data

    Article • June 2017, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  82. Quantification of within-sample genetic heterogeneity from SNP-array data

    Article • Scientific Reports, June 2017, Nature

    Dr Trevor A Graham

  83. Between-region genetic divergence reflects the mode and tempo of tumor evolution

    Article • Nature Genetics, June 2017, Nature

    Dr Trevor A Graham

  84. Catch my drift? Making sense of genomic intra-tumour heterogeneity

    Article • Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, January 2017, Elsevier

    Dr Trevor A Graham

  85. Quantification of subclonal selection in cancer from bulk sequencing data

    Article • December 2016, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  86. Measuring cancer evolution from the genome

    Article • The Journal of Pathology, November 2016, Wiley

    Dr Trevor A Graham

  87. New paradigms in clonal evolution: punctuated equilibrium in cancer

    Article • The Journal of Pathology, August 2016, Wiley

    Dr Trevor A Graham

  88. Tumour Cell Heterogeneity

    Article • F1000Research, February 2016, Faculty of 1000, Ltd.

    Dr Trevor A Graham

  89. Identification of neutral tumor evolution across cancer types

    Article • Nature Genetics, January 2016, Nature

    Dr Trevor A Graham

  90. Pan-cancer analysis of the extent and consequences of intratumor heterogeneity

    Article • Nature Medicine, November 2015, Nature

    Dr Trevor A Graham

  91. Derivation of genetic biomarkers for cancer risk stratification in Barrett’s oesophagus: a prospective cohort study

    Article • Gut, June 2015, BMJ

    Dr Trevor A Graham

  92. Solutions to Peto's paradox revealed by mathematical modelling and cross-species cancer gene analysis

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, June 2015, Royal Society Publishing

    Dr Trevor A Graham

  93. Krt19+/Lgr5− Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine

    Article • Cell Stem Cell, June 2015, Elsevier

    Dr Trevor A Graham

  94. Forty-Year Analysis of Colonoscopic Surveillance Program for Neoplasia in Ulcerative Colitis: An Updated Overview

    Article • The American Journal of Gastroenterology, March 2015, Nature

    Dr Trevor A Graham

  95. Characterization of LGR5 stem cells in colorectal adenomas and carcinomas

    Article • Scientific Reports, March 2015, Springer Science + Business Media

    Dr Trevor A Graham

  96. A pan-cancer signature of neutral tumor evolution

    Article • February 2015, Cold Spring Harbor Laboratory Press

    Dr Trevor A Graham

  97. A Big Bang model of human colorectal tumor growth

    Article • Nature Genetics, February 2015, Springer Science + Business Media

    Dr Trevor A Graham

  98. Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential

    Article • Cell, January 2015, Elsevier

    Dr Trevor A Graham

  99. Location, location, location! The reality of life for an intestinal stem cell in the crypt

    Article • The Journal of Pathology, August 2014, Wiley

    Dr Trevor A Graham

  100. Quantification of Crypt and Stem Cell Evolution in the Normal and Neoplastic Human Colon

    Article • Cell Reports, August 2014, Elsevier

    Professor Stuart A McDonald, Dr Trevor A Graham, Biancastella Cereser

  101. Cell migration leads to spatially distinct but clonally related airway cancer precursors

    Article • Thorax, February 2014, BMJ

    Dr Trevor A Graham

  102. Re: Mitochondria and Tumor Progression in Ulcerative Colitis

    Article • JNCI Journal of the National Cancer Institute, January 2014, Oxford University Press (OUP)

    Dr Trevor A Graham

  103. Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors

    Article • eLife, October 2013, eLife

    Professor Stuart A McDonald, Dr Trevor A Graham

  104. Clonal Selection and Persistence in Dysplastic Barrettʼs Esophagus and Intramucosal Cancers After Failed Radiofrequency Ablation

    Article • The American Journal of Gastroenterology, October 2013, Wolters Kluwer Health

    Professor Stuart A McDonald, Dr Trevor A Graham

  105. Crypt dysplasia in Barrett's oesophagus shows clonal identity between crypt and surface cells

    Article • The Journal of Pathology, August 2013, Wiley

    Professor Stuart A McDonald, Dr Trevor A Graham

  106. Lineage tracing reveals multipotent stem cells maintain human adenomas and the pattern of clonal expansion in tumor evolution

    Article • Proceedings of the National Academy of Sciences, June 2013, Proceedings of the National Academy of Sciences

    Dr Trevor A Graham, Biancastella Cereser

  107. What Can Be Learnt about Disease Progression in Breast Cancer Dormancy from Relapse Data?

    Article • PLOS One, May 2013, PLOS

    Dr Trevor A Graham

  108. Pre-tumour clones, periodic selection and clonal interference in the origin and progression of gastrointestinal cancer: potential for biomarker development

    Article • The Journal of Pathology, February 2013, Wiley

    Dr Trevor A Graham

  109. LRIG1 regulates cadherin-dependent contact inhibition directing epithelial homeostasis and pre-invasive squamous cell carcinoma development

    Article • The Journal of Pathology, February 2013, Wiley

    Dr Trevor A Graham, Professor Fiona M Watt

  110. Modelling the evolution of genetic instability during tumour progression

    Article • Evolutionary Applications, November 2012, Wiley

    Dr Trevor A Graham

  111. Resolving the stem-cell debate

    Article • Nature, August 2012, Springer Science + Business Media

    Dr Trevor A Graham

  112. Field Cancerization in the Intestinal Epithelium of Patients With Crohn's Ileocolitis

    Article • Gastroenterology, April 2012, Elsevier

    Professor Stuart A McDonald, Dr Trevor A Graham

  113. A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts

    Article • Gut, January 2012, BMJ

    Dr Trevor A Graham

  114. Utilizing DNA Mutations to Trace Epithelial Cell Lineages in Human Tissues

    Article • January 2012, Springer Science + Business Media

    Dr Trevor A Graham

  115. Barrett's metaplasia glands are clonal, contain multiple stem cells and share a common squamous progenitor

    Article • Gut, December 2011, BMJ

    Professor Stuart A McDonald, Dr Trevor A Graham, Professor Janusz Antoni Jankowski

  116. Clonal architecture of human prostatic epithelium in benign and malignant conditions

    Article • The Journal of Pathology, August 2011, Wiley

    Professor Stuart A McDonald, Dr Trevor A Graham

  117. Field cancerization in the GI tract

    Article • Future Oncology, August 2011, Future Medicine

    Professor Stuart A McDonald, Dr Trevor A Graham

  118. The human urothelium consists of multiple clonal units, each maintained by a stem cell

    Article • The Journal of Pathology, July 2011, Wiley

    Professor Stuart A McDonald, Dr Trevor A Graham

  119. Use of Methylation Patterns to Determine Expansion of Stem Cell Clones in Human Colon Tissue

    Article • Gastroenterology, April 2011, Elsevier

    Professor Stuart A McDonald, Dr Trevor A Graham

  120. The Clonal Origins of Dysplasia From Intestinal Metaplasia in the Human Stomach

    Article • Gastroenterology, April 2011, Elsevier

    Professor Stuart A McDonald, Dr Trevor A Graham, Professor Janusz Antoni Jankowski

  121. Stem cells and their implications for colorectal cancer

    Article • Nature Reviews Gastroenterology & Hepatology, February 2011, Springer Science + Business Media

    Dr Trevor A Graham

  122. Stem Cells and Inflammation in the Intestine

    Article • January 2011, Springer Science + Business Media

    Dr Trevor A Graham

  123. Field defects in DNA repair: is loss of MGMT an initial event in colorectal carcinogenesis?

    Article • Gut, October 2010, BMJ

    Dr Trevor A Graham

  124. Breast Cancer Dormancy Can Be Maintained by Small Numbers of Micrometastases

    Article • Cancer Research, May 2010, American Association for Cancer Research (AACR)

    Dr Trevor A Graham

  125. Spindles losing their bearings: Does disruption of orientation in stem cells predict the onset of cancer?

    Article • BioEssays, May 2010, Wiley

    Dr Trevor A Graham

  126. Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas

    Article • Gastroenterology, April 2010, Elsevier

    Professor Stuart A McDonald, Dr Trevor A Graham, Professor Janusz Antoni Jankowski

  127. Genetic diversity during the development of Barrett's oesophagus-associated adenocarcinoma: how, when and why?

    Article • Biochemical Society Transactions, April 2010, Portland Press Ltd.

    Dr Trevor A Graham

  128. Long-term proton pump induced hypergastrinaemia does induce lineage-specific restitution but not clonal expansion in benign Barrett's oesophagus in vivo

    Article • Gut, August 2009, BMJ

    Dr Trevor A Graham, Professor Janusz Antoni Jankowski

  129. Stem cells and solid cancers

    Article • Virchows Archiv, June 2009, Springer Science + Business Media

    Professor Stuart A McDonald, Dr Trevor A Graham

  130. Clonality, Founder Mutations, and Field Cancerization in Human Ulcerative Colitis–Associated Neoplasia

    Article • Gastroenterology, February 2009, Elsevier

    Professor Stuart A McDonald, Dr Trevor A Graham, Professor Janusz Antoni Jankowski

  131. Investigating the fixation and spread of mutations in the gastrointestinal epithelium

    Article • Future Oncology, December 2008, Future Medicine

    Dr Trevor A Graham

  132. A comprehensive genetic profile of phyllodes tumours of the breast detects important mutations, intra-tumoral genetic heterogeneity and new genetic changes on recurrence

    Article • The Journal of Pathology, January 2008, Wiley

    Dr Trevor A Graham

  133. Most low-level microsatellite instability in colorectal cancers can be explained without an elevated slippage rate

    Article • The Journal of Pathology, January 2008, Wiley

    Dr Trevor A Graham

  134. Analysis of copy number changes suggests chromosomal instability in a minority of large colorectal adenomas

    Article • The Journal of Pathology, January 2007, Wiley

    Dr Trevor A Graham