All Stories

  1. Pathogenic Keratinocyte States and Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa

    Article • November 2025, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe, Professor Fiona M Watt

  2. Unlocking the full potential of Oxford Nanopore reads with NOVOLoci

    Article • August 2025, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  3. The complete mitogenome of an unidentified Oikopleura species

    Article • F1000Research, May 2025, Faculty of 1000, Ltd.

    Professor Nicholas Luscombe

  4. Genomic insights and the conservation potential of captive breeding: The case of Chinese alligator

    Article • Science Advances, April 2025, American Association for the Advancement of Science

    Professor Nicholas Luscombe

  5. Transcriptomes of a fast-developing chordate uncover drastic differences in transcription factors and localized maternal RNA composition compared with those of ascidians

    Article • Development, March 2025, The Company of Biologists

    Professor Nicholas Luscombe

  6. The complete mitogenome of an unidentified Oikopleura species

    Article • F1000Research, March 2025, Faculty of 1000, Ltd.

    Professor Nicholas Luscombe

  7. Less, but more: new insights from appendicularians on chordate Fgf evolution and the divergence of tunicate lifestyles

    Article • Molecular Biology and Evolution, December 2024, Oxford University Press (OUP)

    Professor Nicholas Luscombe

  8. Cross-tissue isoform switches by human transcription factors suggest a widespread regulatory mechanism

    Article • November 2024, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  9. The complete mitogenome of an unidentified Oikopleura species

    Article • F1000Research, November 2024, Faculty of 1000, Ltd.

    Professor Nicholas Luscombe

  10. Integrative analysis of higher-order transcriptome organisation and RNA condensation principles

    Article • October 2024, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  11. Less, but more: new insights from appendicularians on chordateFgfevolution and the divergence of tunicate lifestyles

    Article • August 2024, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  12. Tracing Homopolymers in Oikopleura dioica's Mitogenome

    Article • Genome Biology and Evolution, August 2024, Oxford University Press (OUP)

    Professor Nicholas Luscombe

  13. The complete mitogenome of an unidentifiedOikopleuraspecies

    Article • July 2024, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  14. Tracing Homopolymers inOikopleura dioica’s mitogenome

    Article • May 2024, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  15. A computationally-enhanced hiCLIP atlas reveals Staufen1-RNA binding features and links 3′ UTR structure to RNA metabolism

    Article • Nucleic Acids Research, April 2023, Oxford University Press (OUP)

    Professor Nicholas Luscombe

  16. clipplotr - a comparative visualisation and analysis tool for CLIP data

    Article • RNA, March 2023, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  17. A computationally-enhanced hiCLIP atlas reveals Staufen1 RNA binding features and links 3’ UTR structure to RNA metabolism

    Article • June 2022, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  18. A single-cell atlas of bobtail squid visual and nervous system highlights molecular principles of convergent evolution

    Article • May 2022, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  19. Automated phenol-chloroform extraction of high molecular weight genomic DNA for use in long-read single-molecule sequencing

    Article • F1000Research, February 2022, Faculty of 1000, Ltd.

    Professor Nicholas Luscombe

  20. Annelid functional genomics reveal the origins of bilaterian life cycles

    Article • February 2022, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  21. Automated phenol-chloroform extraction of high molecular weight genomic DNA for use in long-read single-molecule sequencing

    Article • January 2022, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  22. Development of the Research Data Archive at OIST

    Article • January 2022, Springer Science + Business Media

    Professor Nicholas Luscombe

  23. Chromatin-contact atlas reveals disorder-mediated protein interactions and moonlighting chromatin-associated RBPs

    Article • Nucleic Acids Research, December 2021, Oxford University Press (OUP)

    Professor Nicholas Luscombe

  24. clipplotr - a comparative visualisation and analysis tool for CLIP data

    Article • September 2021, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  25. Suppressed eusocial reproduction supports evolutionary convergence over co-option

    Article • July 2021, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  26. Ultraplex: A rapid, flexible, all-in-one fastq demultiplexer

    Article • Wellcome Open Research, June 2021, Faculty of 1000, Ltd.

    Professor Nicholas Luscombe

  27. ChromWave: Deciphering the DNA-encoded competition between transcription factors and nucleosomes with deep neural networks

    Article • March 2021, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  28. psiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation

    Article • Nature Communications, March 2021, Springer Science + Business Media

    Professor Nicholas Luscombe

  29. H3S28P Antibody Staining of Okinawan Oikopleura dioica Suggests the Presence of Three Chromosomes

    Article • F1000Research, March 2021, Faculty of 1000, Ltd.

    Professor Nicholas Luscombe

  30. Clinically Relevant Vulnerabilities of Deep Machine Learning Systems for Skin Cancer Diagnosis

    Article • Journal of Investigative Dermatology, September 2020, Elsevier

    Professor Nicholas Luscombe, Professor Fiona M Watt

  31. SPACE exploration of chromatin proteome to reveal associated RNA-binding proteins

    Article • July 2020, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  32. CD147 (BSG) but not ACE2 expression is detectable in vascular endothelial cells within single cell RNA sequencing datasets derived from multiple tissues in healthy individuals

    Article • May 2020, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe, Professor Fiona M Watt

  33. Finding cell-specific expression patterns in the early Ciona embryo with single-cell RNA-seq

    Article • Scientific Reports, March 2020, Springer Science + Business Media

    Professor Nicholas Luscombe

  34. PsiCLIP reveals dynamic RNA binding by DEAH-box helicases before and after exon ligation

    Article • March 2020, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  35. Nucleosome positioning stability is a modulator of germline mutation rate variation across the human genome

    Article • Nature Communications, March 2020, Springer Science + Business Media

    Professor Nicholas Luscombe, Cai Li

  36. What is AI? Applications of artificial intelligence to dermatology

    Article • British Journal of Dermatology, January 2020, Wiley

    Professor Fiona M Watt, Professor Nicholas Luscombe

  37. Intergenic RNA mainly derives from nascent transcripts of known genes

    Article • January 2020, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  38. Widespread use of the “ascidian” mitochondrial genetic code in tunicates

    Article • December 2019, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  39. RNA modifications detection by comparative Nanopore direct RNA sequencing

    Article • November 2019, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  40. AI networks work together to simulate human cells

    Article • February 2018, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe, Arsham Ghahramani

  41. Machine learning models in electronic health records can outperform conventional survival models for predicting patient mortality in coronary artery disease

    Article • January 2018, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe

  42. Integrated analysis sheds light on evolutionary trajectories of young transcription start sites in the human genome

    Article • September 2017, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe, Cai Li

  43. Genomic landscape of oxidative DNA damage and repair reveals regioselective protection from mutagenesis

    Article • July 2017, Cold Spring Harbor Laboratory Press

    Professor Nicholas Luscombe