All Stories

  1. Cryo-EM structure of the Ebola virus nucleoprotein–RNA complex

    Article • Acta Crystallographica Section F Structural Biology Communications, April 2019, International Union of Crystallography

    Erica Ollmann Saphire

  2. Structural Basis of Pan-Ebolavirus Neutralization by a Human Antibody against a Conserved, yet Cryptic Epitope

    Article • mBio, September 2018, ASM Journals

    Erica Ollmann Saphire

  3. Crystal Structure of the Marburg Virus VP35 Oligomerization Domain

    Article • Journal of Virology, November 2016, ASM Journals

    Erica Ollmann Saphire

  4. Crystal Structure of the Oligomeric Form of Lassa Virus Matrix Protein Z

    Article • Journal of Virology, February 2016, ASM Journals

    Erica Ollmann Saphire

  5. Crystal Structure of Marburg Virus VP40 Reveals a Broad, Basic Patch for Matrix Assembly and a Requirement of the N-Terminal Domain for Immunosuppression

    Article • Journal of Virology, December 2015, ASM Journals

    Erica Ollmann Saphire

  6. Structure of the LCMV nucleoprotein provides a template for understanding arenavirus replication and immunosuppression

    Article • Acta Crystallographica Section D Biological Crystallography, May 2014, International Union of Crystallography

    Erica Ollmann Saphire

  7. Structural insights into RNA encapsidation and helical assembly of the Toscana virus nucleoprotein

    Article • Nucleic Acids Research, March 2014, Oxford University Press (OUP)

    Erica Ollmann Saphire, Friedemann Weber

  8. Structure of theReston ebolavirusVP30 C-terminal domain

    Article • Acta Crystallographica Section F Structural Biology Communications, March 2014, International Union of Crystallography

    Erica Ollmann Saphire

  9. Lassa Fever in Post-Conflict Sierra Leone

    Article • PLoS Neglected Tropical Diseases, March 2014, PLOS

    Erica Ollmann Saphire

  10. Correction: The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold

    Article • PLoS Pathogens, December 2013, PLOS

    Erica Ollmann Saphire

  11. IgG hexamerization mediates efficient C1q docking and complement-dependent cytotoxicity (CDC)

    Article • Molecular Immunology, December 2013, Elsevier

    Erica Ollmann Saphire

  12. Crystal structure of the Nipah virus phosphoprotein tetramerization domain

    Article • November 2013, Protein Data Bank, Rutgers University

    Erica Ollmann Saphire

  13. An update on the use of antibodies against the filoviruses

    Article • Immunotherapy, November 2013, Future Medicine

    Erica Ollmann Saphire

  14. Crystal Structure of the Nipah Virus Phosphoprotein Tetramerization Domain

    Article • Journal of Virology, October 2013, ASM Journals

    Erica Ollmann Saphire

  15. Discussions and decisions of the 2012–2014 International Committee on Taxonomy of Viruses (ICTV) Filoviridae Study Group, January 2012–June 2013

    Article • Archives of Virology, October 2013, Springer Science + Business Media

    Erica Ollmann Saphire, Dr Jens H. Kuhn

  16. Structural Rearrangement of Ebola Virus VP40 Begets Multiple Functions in the Virus Life Cycle

    Article • Cell, August 2013, Elsevier

    Erica Ollmann Saphire

  17. Ebolavirus VP35 Coats the Backbone of Double-Stranded RNA for Interferon Antagonism

    Article • Journal of Virology, July 2013, ASM Journals

    Erica Ollmann Saphire, Dr Jean-Philippe Julien

  18. Virus nomenclature below the species level: a standardized nomenclature for laboratory animal-adapted strains and variants of viruses assigned to the family Filoviridae

    Article • Archives of Virology, January 2013, Springer Science + Business Media

    Erica Ollmann Saphire, Dr Jens H. Kuhn

  19. Two Synthetic Antibodies that Recognize and Neutralize Distinct Proteolytic Forms of the Ebola Virus Envelope Glycoprotein

    Article • ChemBioChem, October 2012, Wiley

    Erica Ollmann Saphire

  20. Virus nomenclature below the species level: a standardized nomenclature for natural variants of viruses assigned to the family Filoviridae

    Article • Archives of Virology, September 2012, Springer Science + Business Media

    Erica Ollmann Saphire, Dr Jens H. Kuhn

  21. Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism

    Article • PLoS Pathogens, September 2012, PLOS

    Erica Ollmann Saphire, Dr Jean-Philippe Julien

  22. Structural Basis for the dsRNA Specificity of the Lassa Virus NP Exonuclease

    Article • PLoS ONE, August 2012, PLOS

    Erica Ollmann Saphire

  23. The ebolavirus VP24 interferon antagonist

    Article • Virulence, August 2012, Taylor & Francis

    Erica Ollmann Saphire

  24. Structural Basis for Differential Neutralization of Ebolaviruses

    Article • Viruses, April 2012, MDPI AG

    Erica Ollmann Saphire

  25. Editorial overview

    Article • Current Opinion in Virology, April 2012, Elsevier

    Erica Ollmann Saphire

  26. Hiding the evidence: two strategies for innate immune evasion by hemorrhagic fever viruses

    Article • Current Opinion in Virology, April 2012, Elsevier

    Erica Ollmann Saphire

  27. The Ebola Virus Interferon Antagonist VP24 Directly Binds STAT1 and Has a Novel, Pyramidal Fold

    Article • PLoS Pathogens, February 2012, PLOS

    Erica Ollmann Saphire

  28. Structure of an Antibody in Complex with Its Mucin Domain Linear Epitope That Is Protective against Ebola Virus

    Article • Journal of Virology, December 2011, ASM Journals

    Erica Ollmann Saphire

  29. A shared structural solution for neutralizing ebolaviruses

    Article • Nature Structural & Molecular Biology, November 2011, Springer Science + Business Media

    Erica Ollmann Saphire

  30. Ebola Virus Glycoprotein Needs an Additional Trigger, beyond Proteolytic Priming for Membrane Fusion

    Article • PLoS Neglected Tropical Diseases, November 2011, PLOS

    Erica Ollmann Saphire

  31. Crystal structure of the Lassa virus nucleoprotein–RNA complex reveals a gating mechanism for RNA binding

    Article • Proceedings of the National Academy of Sciences, November 2011, Proceedings of the National Academy of Sciences

    Erica Ollmann Saphire

  32. Measles virus fusion shifts into gear

    Article • Nature Structural & Molecular Biology, February 2011, Springer Science + Business Media

    Erica Ollmann Saphire

  33. Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3′ to 5′ exonuclease activity essential for immune suppression

    Article • Proceedings of the National Academy of Sciences, January 2011, Proceedings of the National Academy of Sciences

    Erica Ollmann Saphire

  34. Ebolavirus VP35 uses a bimodal strategy to bind dsRNA for innate immune suppression

    Article • Proceedings of the National Academy of Sciences, December 2009, Proceedings of the National Academy of Sciences

    Erica Ollmann Saphire

  35. Ebolavirusglycoprotein structure and mechanism of entry

    Article • Future Virology, November 2009, Future Medicine

    Erica Ollmann Saphire

  36. Techniques and tactics used in determining the structure of the trimericebolavirusglycoprotein

    Article • Acta Crystallographica Section D Biological Crystallography, October 2009, International Union of Crystallography

    Erica Ollmann Saphire

  37. Neutralizing ebolavirus: structural insights into the envelope glycoprotein and antibodies targeted against it

    Article • Current Opinion in Structural Biology, August 2009, Elsevier

    Erica Ollmann Saphire

  38. An efficient platform for screening expression and crystallization of glycoproteins produced in human cells

    Article • Nature Protocols, April 2009, Springer Science + Business Media

    Erica Ollmann Saphire

  39. Erica Ollmann Saphire

    Article • Nature, July 2008, Springer Science + Business Media

    Erica Ollmann Saphire

  40. Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor

    Article • Nature, July 2008, Springer Science + Business Media

    Erica Ollmann Saphire

  41. Complex of a Protective Antibody with Its Ebola Virus GP Peptide Epitope: Unusual Features of a Vλx Light Chain

    Article • Journal of Molecular Biology, January 2008, Elsevier

    Erica Ollmann Saphire

  42. Structure of a High-affinity “Mimotope” Peptide Bound to HIV-1-neutralizing Antibody b12 Explains its Inability to Elicit gp120 Cross-reactive Antibodies

    Article • Journal of Molecular Biology, June 2007, Elsevier

    Erica Ollmann Saphire, Dr Michael B Zwick

  43. Ebola Virus VP35 Protein Binds Double-Stranded RNA and Inhibits Alpha/Beta Interferon Production Induced by RIG-I Signaling

    Article • Journal of Virology, June 2006, ASM Journals

    Erica Ollmann Saphire, Professor Luis Martinez-Sobrido

  44. gp41: HIV's shy protein

    Article • Nature Reports Stem Cells, February 2004, Springer Science + Business Media

    Erica Ollmann Saphire, Dr Michael B Zwick

  45. Recurring conformation of the human immunodeficiency virus type 1 gp120 V3 loop

    Article • Virology, October 2003, Elsevier

    Erica Ollmann Saphire

  46. The Carbohydrate Epitope of the Neutralizing Anti-HIV-1 Antibody 2G12

    Article • January 2003, Springer Science + Business Media

    Erica Ollmann Saphire

  47. Crystal Structure of an Intact Human IgG: Antibody Asymmetry, Flexibility, and a Guide for HIV-1 Vaccine Design

    Article • January 2003, Springer Science + Business Media

    Erica Ollmann Saphire, Dr Michael B Zwick

  48. Fine Mapping of the Interaction of Neutralizing and Nonneutralizing Monoclonal Antibodies with the CD4 Binding Site of Human Immunodeficiency Virus Type 1 gp120

    Article • Journal of Virology, January 2003, ASM Journals

    Erica Ollmann Saphire

  49. The Broadly Neutralizing Anti-Human Immunodeficiency Virus Type 1 Antibody 2G12 Recognizes a Cluster of α1→2 Mannose Residues on the Outer Face of gp120

    Article • Journal of Virology, July 2002, ASM Journals

    Erica Ollmann Saphire

  50. Contrasting IgG Structures Reveal Extreme Asymmetry and Flexibility

    Article • Journal of Molecular Biology, May 2002, Elsevier

    Erica Ollmann Saphire

  51. GP120: Biologic Aspects of Structural Features

    Article • Annual Review of Immunology, April 2001, Annual Reviews

    Erica Ollmann Saphire

  52. Crystallization and preliminary structure determination of an intact human immunoglobulin, b12: an antibody that broadly neutralizes primary isolates of HIV-1

    Article • Acta Crystallographica Section D Biological Crystallography, January 2001, International Union of Crystallography

    Erica Ollmann Saphire