All Stories

  1. A SAXS-based approach to rationally evaluate radical scavengers – toward eliminating radiation damage in solution and crystallographic studies
  2. SAXS studies of X-ray induced disulfide bond damage: Engineering high-resolution insight from a low-resolution technique
  3. Crystal structure of Latency Associated Peptide unbound to TGF-beta1
  4. Structural insights into conformational switching in latency-associated peptide between transforming growth factor β-1 bound and unbound states
  5. High-Throughput PIXE as an Essential Quantitative Assay for Accurate Metalloprotein Structural Analysis: Development and Application
  6. Structural knowledge or X-ray damage? A case study on xylose isomerase illustrating both
  7. Using low X-ray doses to understand therapeutically relevant structural changes
  8. Protein and RNA dynamical fingerprinting
  9. Classification of crystallization outcomes using deep convolutional neural networks
  10. Moving in the Right Direction: Protein Vibrations Steering Function
  11. Double-flow focused liquid injector for efficient serial femtosecond crystallography
  12. Moving in the Right Direction: Protein Vibrations Steering Function
  13. Touchscreen interfaces make complex tasks simple.
  14. Predicting crystallization from bioinformatic properties
  15. The detection and subsequent volume optimization of biological nanocrystals
  16. The Structure of the PanD/PanZ Protein Complex Reveals Negative Feedback Regulation of Pantothenate Biosynthesis by Coenzyme A
  17. Wild type T4 lysozyme structure
  18. How to confirm your SAXS data quality
  19. A hybrid NMR/SAXS-based approach for discriminating oligomeric protein interfaces using Rosetta
  20. Identifying, studying and making good use of macromolecular crystals
  21. Statistical Analysis of Crystallization Database Links Protein Physico-Chemical Features with Crystallization Mechanisms
  22. Crystallization screening: the influence of history on current practice
  23. Comparing Chemistry to Outcome: The Development of a Chemical Distance Metric, Coupled with Clustering and Hierarchal Visualization Applied to Macromolecular Crystallography
  24. A new view on crystal harvesting
  25. Neutron structure of the cyclic glucose-bound xylose isomerase E186Q mutant
  26. Optical measurements of long-range protein vibrations
  27. Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies
  28. Faculty of 1000 evaluation for Accurate assessment of mass, models and resolution by small-angle scattering.
  29. The Structure of Yeast Glutaminyl-tRNA Synthetase and Modeling of Its Interaction with tRNA
  30. Purification and SAXS Analysis of the Integrin Linked Kinase, PINCH, Parvin (IPP) Heterotrimeric Complex
  31. Faculty of 1000 evaluation for Breaking the radiation damage limit with cryo-SAXS.
  32. Orientation sensitive Terahertz resonances observed in protein crystals
  33. On the need for an international effort to capture, share and use crystallization screening data
  34. Structural conservation of an ancient tRNA sensor in eukaryotic glutaminyl-tRNA synthetase
  35. Macromolecular crystallization and crystal perfection, by Naomi E. Chayen, John R. Helliwell, and Edward H. Snell
  36. Small angle X‐ray scattering as a complementary tool for high‐throughput structural studies
  37. Lessons from high-throughput protein crystallization screening: 10 years of practical experience
  38. What’s in a Drop? Correlating Observations and Outcomes to Guide Macromolecular Crystallization Experiments
  39. Crystal cookery – using high-throughput technologies and the grocery store as a teaching tool
  40. A book about Macromolecular Crystallization and Crystal Perfection
  41. Crystallization theory
  42. Optimization
  43. Experimental aspects
  44. Introduction
  45. Screening
  46. Unusual diffraction geometries
  47. Alternative approaches
  48. Membrane proteins
  49. The X‐ray laser and the single molecule — no crystal needed?
  50. Other macromolecular crystal diffraction disorders
  51. Practical methods of crystallization
  52. Protein powders — making the most of tiny crystallites in bulk
  53. Degradation and improvement of crystal perfection
  54. Overall summary and future thoughts
  55. Macromolecular crystals and twinning
  56. Making the most of difficult crystals — beamline and detector optimization
  57. Strategies to apply when high‐quality crystals cannot be obtained
  58. Analysis of the molecular short‐range order
  59. Analysis of long‐range order
  60. Sliding Clamp–DNA Interactions Are Required for Viability and Contribute to DNA Polymerase Management in Escherichia coli
  61. The application and use of chemical space mapping to interpret crystallization screening results
  62. Establishing a training set through the visual analysis of crystallization trials. Part I: ∼150 000 images
  63. Establishing a training set through the visual analysis of crystallization trials. Part II: crystal examples
  64. AutoSherlock: a program for effective crystallization data analysis
  65. Glycerol concentrations required for the successful vitrification of cocktail conditions in a high-throughput crystallization screen
  66. Structure of the Full-length Human RPA14/32 Complex Gives Insights into the Mechanism of DNA Binding and Complex Formation
  67. Changes to crystals ofEscherichia coliβ-galactosidase during room-temperature/low-temperature cycling and their relation to cryo-annealing
  68. Efficient optimization of crystallization conditions by manipulation of drop volume ratio and temperature
  69. Non-invasive measurement of X-ray beam heating on a surrogate crystal sample
  70. Optimizing crystal volume for neutron diffraction: D-xylose isomerase
  71. A quasi-Laue neutron crystallographic study of d-xylose isomerase
  72. Extracting trends from two decades of microgravity macromolecular crystallization history
  73. The why, how, when, and what happened of crystallization in space
  74. Finding a cold needle in a warm haystack: infrared imaging applied to locating cryocooled crystals in loops
  75. First results of digital topography applied to macromolecular crystals
  76. Imaging modulated reflections from a semi-crystalline state of profilin:actin crystals
  77. Macromolecular Crystal Quality
  78. The development and application of a method to quantify the quality of cryoprotectant solutions using standard area-detector X-ray images
  79. Investigating the Effect of Impurities on Macromolecule Crystal Growth in Microgravity
  80. Microgravity and Macromolecular Crystallography
  81. BEAM-ish: a graphical user interface for the physical characterization of macromolecular crystals
  82. Cryo-trapping the six-coordinate, distorted-octahedral active site of manganese superoxide dismutase 1 1Edited by R. Huber
  83. The Effect of Temperature and Solution pH on the Nucleation of Tetragonal Lysozyme Crystals
  84. Crystallization of chicken egg white lysozyme from assorted sulfate salts
  85. Protein crystal movements and fluid flows during microgravity growth
  86. Crystallization of chicken egg-white lysozyme from ammonium sulfate
  87. Partial Improvement of Crystal Quality for Microgravity-Grown Apocrustacyanin C1
  88. CCD video observation of microgravity crystallization: apocrustacyanin C1
  89. Trends and Challenges in Experimental Macromolecular Crystallography
  90. Lysozyme Crystal Growth Kinetics Monitored Using a Mach–Zehnder Interferometer
  91. Microgravity crystal growth improved long range crystal order
  92. Time-resolved biological and perturbation chemical crystallography: Laue and monochromatic developments
  93. Image-Plate Synchrotron Laue Data Collection and Subsequent Structural Analysis of a Small Test Crystal of a Nickel-Containing Aluminophosphate
  94. An investigation of the perfection of lysozyme protein crystals grown in microgravity and on earth