All Stories

  1. The X-ray crystal structure of the N-terminal domain of Ssr4, a Schizosaccharomyces pombe chromatin-remodelling protein

    Article • Acta Crystallographica Section F Structural Biology Communications, November 2020, International Union of Crystallography

    Dr Thomas S Peat

  2. Crystal structures of human ENPP1 in apo and bound forms

    Article • Acta Crystallographica Section D Structural Biology, August 2020, International Union of Crystallography

    Dr Thomas S Peat

  3. Fragment screening for a protein-protein interaction inhibitor to WDR5

    Article • Structural Dynamics, November 2019, American Institute of Physics

    Dr Thomas S Peat

  4. The evolving story of AtzT, a periplasmic binding protein

    Article • Acta Crystallographica Section D Structural Biology, October 2019, International Union of Crystallography

    Dr Thomas S Peat, Dr Colin Scott

  5. Structures of the transcriptional regulator BgaR, a lactose sensor

    Article • Acta Crystallographica Section D Structural Biology, June 2019, International Union of Crystallography

    Dr Thomas S Peat

  6. Crystal structure of a putrescine aminotransferase fromPseudomonassp. strain AAC

    Article • Acta Crystallographica Section F Structural Biology Communications, January 2017, International Union of Crystallography

    Dr Thomas S Peat, Dr Colin Scott

  7. The structure of vanin 1: a key enzyme linking metabolic disease and inflammation

    Article • Acta Crystallographica Section D Biological Crystallography, November 2014, International Union of Crystallography

    Dr Thomas S Peat

  8. Unprecedented conformational flexibility revealed in the ligand-binding domains of theBovicola ovisecdysone receptor (EcR) and ultraspiracle (USP) subunits

    Article • Acta Crystallographica Section D Biological Crystallography, June 2014, International Union of Crystallography

    Dr Thomas S Peat, Dr Bin Ren

  9. 300-Fold Increase in Production of the Zn2+-Dependent Dechlorinase TrzN in Soluble Form via Apoenzyme Stabilization

    Article • Applied and Environmental Microbiology, April 2014, ASM Journals

    Dr Thomas S Peat, Dr Colin Scott, Dr Colin Jackson

  10. Cyclic Secondary Sulfonamides: Unusually Good Inhibitors of Cancer-Related Carbonic Anhydrase Enzymes

    Article • Journal of Medicinal Chemistry, April 2014, American Chemical Society (ACS)

    Dr Thomas S Peat

  11. Crystallization and preliminary X-ray diffraction analysis of the amidase domain of allophanate hydrolase fromPseudomonassp. strain ADP

    Article • Acta Crystallographica Section F Structural Biology Communications, February 2014, International Union of Crystallography

    Dr Thomas S Peat, Dr Colin Scott

  12. Interrogating HIV integrase for compounds that bind- a SAMPL challenge

    Article • Journal of Computer-Aided Molecular Design, February 2014, Springer Science + Business Media

    Dr Thomas S Peat

  13. Nitrate in the active site of protein tyrosine phosphatase 1B is a putative mimetic of the transition state

    Article • Acta Crystallographica Section D Biological Crystallography, January 2014, International Union of Crystallography

    Dr Thomas S Peat

  14. Crystallization reports are the backbone ofActa Cryst. F, but do they have any spine?

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, June 2013, International Union of Crystallography

    Dr Thomas S Peat, Dr Marc Kvansakul

  15. Determination of the Structure of the Catabolic N-Succinylornithine Transaminase (AstC) from Escherichia coli

    Article • PLoS ONE, March 2013, PLOS

    Dr Thomas S Peat, Dr Colin Scott

  16. Parallel Screening of Low Molecular Weight Fragment Libraries: Do Differences in Methodology Affect Hit Identification?

    Article • SLAS DISCOVERY, February 2013, Elsevier

    Dr Thomas S Peat, Professor Martin J Scanlon

  17. Fragment Screening for the Modelling Community: SPR, ITC, and Crystallography

    Article • Australian Journal of Chemistry, January 2013, CSIRO Publishing

    Dr Thomas S Peat

  18. Crystal Structure of an Indole-3-Acetic Acid Amido Synthetase from Grapevine Involved in Auxin Homeostasis

    Article • The Plant Cell, November 2012, American Society of Plant Biologists (ASPB)

    Dr Thomas S Peat

  19. On the need for an international effort to capture, share and use crystallization screening data

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, February 2012, International Union of Crystallography

    Dr Thomas S Peat, Joseph R Luft, Dr Edward H Snell

  20. Structure of S. aureus HPPK and the Discovery of a New Substrate Site Inhibitor

    Article • PLoS ONE, January 2012, PLOS

    Dr Thomas S Peat

  21. Crystal structures of novel allosteric peptide inhibitors of HIV integrase in the LEDGF binding site

    Article • January 2012, Protein Data Bank, Rutgers University

    Dr Thomas S Peat

  22. The DINGO dataset: a comprehensive set of data for the SAMPL challenge

    Article • Journal of Computer-Aided Molecular Design, December 2011, Springer Science + Business Media

    Dr Thomas S Peat

  23. Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design

    Article • Antiviral Chemistry and Chemotherapy, January 2011, International Medical Press

    Paul Savage, Dr Thomas S Peat

  24. Identification and characterization of two families of F420H2‐dependent reductases from Mycobacteria that catalyse aflatoxin degradation

    Article • Molecular Microbiology, September 2010, Wiley

    Dr Thomas S Peat, Dr Colin Scott

  25. A Human Monoclonal Antibody against Insulin-Like Growth Factor-II Blocks the Growth of Human Hepatocellular Carcinoma Cell Lines In vitro and In vivo

    Article • Molecular Cancer Therapeutics, June 2010, American Association for Cancer Research (AACR)

    Dr Thomas S Peat

  26. The C6 Web Tool: A Resource for the Rational Selection of Crystallization Conditions

    Article • Crystal Growth & Design, May 2010, American Chemical Society (ACS)

    Dr Thomas S Peat

  27. Practical Aspects of the SAMPL Challenge: Providing an Extensive Experimental Data Set for the Modeling Community

    Article • SLAS DISCOVERY, December 2009, Elsevier

    Dr Thomas S Peat

  28. Crystallization and preliminary X-ray analysis of the complexes between a Fab and two forms of human insulin-like growth factor II

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, August 2009, International Union of Crystallography

    Dr Thomas S Peat

  29. Phoenito experiments: combining the strengths of commercial crystallization automation

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, October 2008, International Union of Crystallography

    Dr Thomas S Peat

  30. Tapping the Protein Data Bank for crystallization information

    Article • Acta Crystallographica Section D Biological Crystallography, November 2005, International Union of Crystallography

    Dr Thomas S Peat