All Stories

  1. Repurposing flavopiridol as an inhaled therapeutic for pulmonary fibrosis

    Article • European Journal of Pharmacology, October 2025, Elsevier

    Professor Dominik R Haudenschild

  2. Spatial transcriptomic applications in orthopedics

    Article • Connective Tissue Research, May 2025, Taylor & Francis

    Professor Dominik R Haudenschild

  3. Clinical and molecular landscape of post-traumatic osteoarthritis

    Article • Connective Tissue Research, April 2025, Taylor & Francis

    Professor Dominik R Haudenschild

  4. CircFUNDC1 interacts with CDK9 to promote mitophagy in nucleus pulposus cells under oxidative stress and ameliorates intervertebral disc degeneration

    Article • Cell Death and Disease, February 2025, Springer Science + Business Media

    Professor Dominik R Haudenschild

  5. Intra-articular injection of an extended-release flavopiridol formulation represents a potential alternative to other intra-articular medications for treating equine joint disease

    Article • American Journal of Veterinary Research, September 2024, American Veterinary Medical Association (AVMA)

    Professor Dominik R Haudenschild

  6. Current trends in the prevention of adhesions after zone 2 flexor tendon repair

    Article • Journal of Orthopaedic Research®, May 2024, Wiley

    Professor Dominik R Haudenschild

  7. Biomimetic Bone-Like Composite Hydrogel Scaffolds Composed of Collagen Fibrils and Natural Hydroxyapatite for Promoting Bone Repair

    Article • ACS Biomaterials Science & Engineering, March 2024, American Chemical Society (ACS)

    Professor Dominik R Haudenschild

  8. CircGNB1 drives osteoarthritis pathogenesis by inducing oxidative stress in chondrocytes

    Article • Clinical and Translational Medicine, August 2023, Wiley

    Professor Dominik R Haudenschild

  9. Acute bone loss following SARS‐CoV‐2 infection in mice

    Article • Journal of Orthopaedic Research®, March 2023, Wiley

    Professor Dominik R Haudenschild

  10. Mechanical Cues for Triggering and Regulating Cellular Movement Selectively at the Single-Cell Level

    Article • The Journal of Physical Chemistry B, January 2023, American Chemical Society (ACS)

    Professor Dominik R Haudenschild

  11. A two-stage digestion of whole murine knee joints for single-cell RNA sequencing

    Article • Osteoarthritis and Cartilage Open, December 2022, Elsevier

    Professor Dominik R Haudenschild

  12. After a knee injury, flavopiridol in an extended-release formulation reduces arthritis.

    Article • Acta Biomaterialia, September 2022, Elsevier

    Professor Dominik R Haudenschild

  13. Production of Inhalable Ultra-Small Particles for Delivery of Anti-Inflammation Medicine via a Table-Top Microdevice

    Article • Micromachines, August 2022, MDPI AG

    Professor Dominik R Haudenschild

  14. CircSLC7A2 protects against osteoarthritis through inhibition of the miR‐4498/TIMP3 axis

    Article • Cell Proliferation, May 2021, Wiley

    Professor Dominik R Haudenschild

  15. Bromodomain-containing-protein-4 and cyclin-dependent-kinase-9 inhibitors interact synergistically in vitro and combined treatment reduces post-traumatic osteoarthritis severity in mice

    Article • Osteoarthritis and Cartilage, January 2021, Elsevier

    Professor Dominik R Haudenschild

  16. Direct Observations of Silver Nanowire-Induced Frustrated Phagocytosis among NR8383 Lung Alveolar Macrophages

    Article • The Journal of Physical Chemistry B, December 2020, American Chemical Society (ACS)

    Professor Dominik R Haudenschild

  17. Direct Visualization of the Binding of Transforming Growth Factor Beta 1 with Cartilage Oligomeric Matrix Protein via High-Resolution Atomic Force Microscopy

    Article • The Journal of Physical Chemistry B, October 2020, American Chemical Society (ACS)

    Professor Dominik R Haudenschild

  18. Cyclin-Dependent Kinase 9 (CDK9) Inhibitor Atuveciclib Suppresses Intervertebral Disk Degeneration via the Inhibition of the NF-κB Signaling Pathway

    Article • Frontiers in Cell and Developmental Biology, September 2020, Frontiers

    Professor Dominik R Haudenschild

  19. Aggrecan and COMP Improve Periosteal Chondrogenesis by Delaying Chondrocyte Hypertrophic Maturation

    Article • Frontiers in Bioengineering and Biotechnology, August 2020, Frontiers

    Professor Dominik R Haudenschild

  20. NADPH oxidases in bone and cartilage homeostasis and disease: A promising therapeutic target

    Article • Journal of Orthopaedic Research®, April 2020, Wiley

    Professor Dominik R Haudenschild

  21. New Means to Control Molecular Assembly

    Article • The Journal of Physical Chemistry C, February 2020, American Chemical Society (ACS)

    Professor Dominik R Haudenschild

  22. Acute Changes in NADPH Oxidase 4 in Early Post‐Traumatic Osteoarthritis

    Article • Journal of Orthopaedic Research®, July 2019, Wiley

    Professor Dominik R Haudenschild

  23. Do early response genes activated by joint injury affect cell metabolomes?

    Article • Osteoarthritis and Cartilage, March 2019, Elsevier

    Professor Dominik R Haudenschild

  24. Label-Free and Direct Visualization of Multivalent Binding of Bone Morphogenetic Protein-2 with Cartilage Oligomeric Matrix Protein

    Article • The Journal of Physical Chemistry B, December 2018, American Chemical Society (ACS)

    Professor Dominik R Haudenschild

  25. Effects of Micronized Cartilage Matrix on Cartilage Repair in Osteochondral Lesions of the Talus

    Article • Cartilage, August 2018, SAGE Publications

    Professor Dominik R Haudenschild

  26. Inhibition of Early Response Genes Prevents Changes in Global Joint Metabolomic Profiles in Mouse Post-Traumatic Osteoarthritis

    Article • July 2018, Cold Spring Harbor Laboratory Press

    Professor Dominik R Haudenschild

  27. Ca2+-Dependent Regulation of NFATc1 via KCa3.1 in Inflammatory Osteoclastogenesis

    Article • The Journal of Immunology, December 2017, The American Association of Immunologists

    Professor Dominik R Haudenschild

  28. Review on the clinical use of stem cells for the purpose of spinal fusion

    Article • Global Spine Journal, September 2017, SAGE Publications

    Professor Dominik R Haudenschild

  29. Powdered Cartilage to help repair damaged ankle cartilage.

    Article • Foot & Ankle Orthopaedics, September 2017, SAGE Publications

    Professor Dominik R Haudenschild

  30. K Ca 3.1 as Master Regulator in Inflammatory Osteoclastogenesis

    Article • Biophysical Journal, February 2017, Elsevier

    Professor Dominik R Haudenschild

  31. Book chapter on how Osteoarthritis begins and becomes more severe over time.

    Article • January 2017, Elsevier

    Professor Dominik R Haudenschild

  32. Forming more bone with less BMP2

    Article • Spine, July 2016, Wolters Kluwer Health

    Professor Dominik R Haudenschild

  33. Joint tissue biomechanics: joint responses to biomechanical impact (theories of growth and adaptation)

    Article • Osteoarthritis and Cartilage, April 2016, Elsevier

    Professor Dominik R Haudenschild

  34. Articular Cartilage Injury and Potential Remedies

    Article • Journal of Orthopaedic Trauma, December 2015, Wolters Kluwer Health

    Professor Dominik R Haudenschild

  35. Cdk9 inhibition protects cartilage from damage caused by mechanical injury

    Article • October 2015, ECM Research Journal

    Professor Dominik R Haudenschild

  36. Review of non-surgical mouse PTOA models

    Article • Osteoarthritis and Cartilage, October 2015, Elsevier

    Professor Dominik R Haudenschild

  37. Imaging Joint Degradation Realtime

    Article • Biochemical and Biophysical Research Communications, May 2015, Elsevier

    Professor Dominik R Haudenschild

  38. The in vivo and in vitro effect of inhibitors of brd4 and cdk9 on early phase of post traumatic osteoarthritis

    Article • Osteoarthritis and Cartilage, April 2015, Elsevier

    Professor Dominik R Haudenschild

  39. Comprehensive transcriptome analysis of aging-related gene expression in early phase of post-traumatic osteoarthritis

    Article • Osteoarthritis and Cartilage, April 2015, Elsevier

    Professor Dominik R Haudenschild

  40. Evidence of in vivo drug delivery via the tat protein transduction domain

    Article • Osteoarthritis and Cartilage, April 2015, Elsevier

    Professor Dominik R Haudenschild

  41. Do Bisphosphonates Affect OA after ACL Tears?

    Article • Arthritis Research & Therapy, January 2015, Springer Science + Business Media

    Professor Dominik R Haudenschild

  42. Non-surgical ACL Rupture Models in Mice (book chapter)

    Article • January 2015, Springer Science + Business Media

    Professor Dominik R Haudenschild

  43. High abundant protein removal from rodent blood for biomarker discovery

    Article • Biochemical and Biophysical Research Communications, December 2014, Elsevier

    Professor Dominik R Haudenschild

  44. Reply

    Article • Arthritis & Rheumatology, November 2014, Wiley

    Professor Dominik R Haudenschild

  45. In vivo fluorescence reflectance imaging of protease activity in a mouse model of post-traumatic osteoarthritis

    Article • Osteoarthritis and Cartilage, October 2014, Elsevier

    Professor Dominik R Haudenschild

  46. Cartilage oligomeric matrix protein and its binding partners in the cartilage extracellular matrix: Interaction, regulation and role in chondrogenesis

    Article • Matrix Biology, July 2014, Elsevier

    Professor Dominik R Haudenschild

  47. Primary Response to Cartilage Injury

    Article • Arthritis & Rheumatology, May 2014, Wiley

    Professor Dominik R Haudenschild

  48. The effect of noggin interference in a rabbit posterolateral spinal fusion model

    Article • European Spine Journal, April 2014, Springer Science + Business Media

    Professor Dominik R Haudenschild

  49. CDK9 inhibition attenuates inflammatory response and apoptosis in cartilage explants to preserve matrix integrity in a single impact mechanical injury model

    Article • Osteoarthritis and Cartilage, April 2014, Elsevier

    Professor Dominik R Haudenschild

  50. Mice null for the alternatively spliced EDA segment of fibronectin exhibit reduced knee inflammation after tibial compression injury

    Article • Osteoarthritis and Cartilage, April 2014, Elsevier

    Professor Dominik R Haudenschild

  51. Comparison of loading rate-dependent injury modes in a murine model of post-traumatic osteoarthritis

    Article • Journal of Orthopaedic Research®, September 2013, Wiley

    Professor Dominik R Haudenschild

  52. LRF promotes stem cells growth and inhibits cartilage differentiation

    Article • Cartilage, July 2013, SAGE Publications

    Professor Dominik R Haudenschild

  53. Cartilage oligomeric matrix protein enhances osteogenesis by directly binding and activating bone morphogenetic protein-2

    Article • Bone, July 2013, Elsevier

    Professor Dominik R Haudenschild

  54. Effect of Age and Cytoskeletal Elements on the Indentation-Dependent Mechanical Properties of Chondrocytes

    Article • PLOS One, April 2013, PLOS

    Professor Dominik R Haudenschild

  55. Early transient induction of IL-6 in a mouse joint injury model

    Article • Osteoarthritis and Cartilage, April 2013, Elsevier

    Professor Dominik R Haudenschild

  56. Interactions between FGF21 and BMP-2 in osteogenesis

    Article • Biochemical and Biophysical Research Communications, March 2013, Elsevier

    Professor Dominik R Haudenschild

  57. c-Maf Transcription Factor Regulates ADAMTS-12 Expression in Human Chondrogenic Cells

    Article • Cartilage, February 2013, SAGE Publications

    Professor Dominik R Haudenschild

  58. Pathogenesis of Osteoarthritis

    Article • January 2013, Elsevier

    Professor Dominik R Haudenschild

  59. Identification of a 3Kbp Mechanoresponsive Promoter Region in the Human Cartilage Oligomeric Matrix Protein Gene

    Article • Tissue Engineering Part A, August 2012, SAGE Publications

    Professor Dominik R Haudenschild

  60. The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance

    Article • Carcinogenesis, July 2012, Oxford University Press (OUP)

    Professor Dominik R Haudenschild

  61. Musculoskeletal changes following non-invasive knee injury using a novel mouse model of post-traumatic osteoarthritis

    Article • Osteoarthritis and Cartilage, July 2012, Elsevier

    Professor Dominik R Haudenschild

  62. Chondrogenic Potential and Homogeneity of Cell Populations of Donor and Recipient Cells in a Fresh Osteochondral Allograft

    Article • Journal of Bone and Joint Surgery, February 2012, The Journal of Bone and Joint Surgery, Inc.

    Professor Dominik R Haudenschild

  63. Enhanced Activity of Transforming Growth Factor β1 (TGF-β1) Bound to Cartilage Oligomeric Matrix Protein

    Article • Journal of Biological Chemistry, December 2011, Elsevier

    Professor Dominik R Haudenschild

  64. Comparative analysis with collagen type II distinguishes cartilage oligomeric matrix protein as a primary TGFβ-responsive gene

    Article • Osteoarthritis and Cartilage, October 2011, Elsevier

    Professor Dominik R Haudenschild

  65. 138 EARLY CHANGES FOLLOWING KNEE INJURY IN NON-INVASIVE MOUSE PTOA MODEL

    Article • Osteoarthritis and Cartilage, September 2011, Elsevier

    Professor Dominik R Haudenschild

  66. 240 COMP BINDS TRANSFORMING GROWTH FACTOR BETA FAMILY LIGANDS TO ENHANCE THEIR ACTIVHY

    Article • Osteoarthritis and Cartilage, September 2011, Elsevier

    Professor Dominik R Haudenschild

  67. Vimentin contributes to changes in chondrocyte stiffness in osteoarthritis

    Article • Journal of Orthopaedic Research®, November 2010, Wiley

    Professor Dominik R Haudenschild

  68. Role of c-Maf in Chondrocyte Differentiation

    Article • Cartilage, August 2010, SAGE Publications

    Professor Dominik R Haudenschild

  69. Rho kinase–dependent activation of SOX9 in chondrocytes

    Article • Arthritis & Rheumatism, January 2010, Wiley

    Professor Dominik R Haudenschild

  70. 212 RHO KINASE PHOSPHORYLATES SOX9 TO ENHANCE TRANSCRIPTIONAL ACTIVITY

    Article • Osteoarthritis and Cartilage, September 2008, Elsevier

    Professor Dominik R Haudenschild

  71. Rho kinase–dependent CCL20 induced by dynamic compression of human chondrocytes

    Article • Arthritis & Rheumatism, August 2008, Wiley

    Professor Dominik R Haudenschild

  72. Dynamic compression of chondrocytes induces a Rho kinase-dependent reorganization of the actin cytoskeleton

    Article • Biorheology The Official Journal of the International Society of Biorheology, January 2008, IOS Press

    Professor Dominik R Haudenschild

  73. Immunolocalization of IL-17A, IL-17B, and Their Receptors in Chondrocytes During Fracture Healing

    Article • Journal of Histochemistry & Cytochemistry, October 2007, SAGE Publications

    Professor Dominik R Haudenschild

  74. Generation of interleukin-17 receptor-like protein (IL-17RL) in prostate by alternative splicing of RNA

    Article • The Prostate, January 2006, Wiley

    Professor Dominik R Haudenschild

  75. P145 RHO KINASE ACTIVITY AND ACTIN CYTOSKELETON REORGANIZATION ARE REQUIRED FOR TRANSFORMING GROWTH FACTOR BETA INDUCED MATRIX SYNTHESIS

    Article • Osteoarthritis and Cartilage, January 2006, Elsevier

    Professor Dominik R Haudenschild

  76. P146 DYNAMIC COMPRESSION OF CHONDROCYTES INDUCES A RHO KINASE-DEPENDENT REORGANIZATION OF THE ACTIN CYTOSKELETON

    Article • Osteoarthritis and Cartilage, January 2006, Elsevier

    Professor Dominik R Haudenschild

  77. Interleukin-17 Receptor-LikeGene Is a Novel Antiapoptotic Gene Highly Expressed in Androgen-Independent Prostate Cancer

    Article • Cancer Research, January 2006, American Association for Cancer Research (AACR)

    Professor Dominik R Haudenschild

  78. Bone Morphogenetic Protein (BMP)-6 Signaling and BMP Antagonist Noggin in Prostate Cancer

    Article • Cancer Research, November 2004, American Association for Cancer Research (AACR)

    Professor Dominik R Haudenschild

  79. Interleukin-17 family and IL-17 receptors

    Article • Cytokine & Growth Factor Reviews, April 2003, Elsevier

    Professor Dominik R Haudenschild

  80. Soluble and Transmembrane Isoforms of Novel Interleukin-17 Receptor-like Protein by RNA Splicing and Expression in Prostate Cancer

    Article • Journal of Biological Chemistry, November 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Dominik R Haudenschild

  81. How do monolayer-expanded chondrocytes re-adapt to 3D culture

    Article • The Anatomical Record, March 2001, Wiley

    Professor Dominik R Haudenschild

  82. Expression of a stable articular cartilage phenotype without evidence of hypertrophy by adult human articular chondrocytes in vitro

    Article • Journal of Orthopaedic Research®, March 1998, Wiley

    Professor Dominik R Haudenschild

  83. Cartilage Matrix Protein: Expression Patterns in Chicken, Mouse, and Humana

    Article • Annals of the New York Academy of Sciences, June 1996, Wiley

    Professor Dominik R Haudenschild

  84. Cartilage matrix protein forms a type II collagen-independent filamentous network: analysis in primary cell cultures with a retrovirus expression system.

    Article • Molecular Biology of the Cell, December 1995, American Society for Cell Biology (ASCB)

    Professor Dominik R Haudenschild

  85. Progression and Recapitulation of the Chondrocyte Differentiation Program: Cartilage Matrix Protein Is a Marker for Cartilage Maturation

    Article • Developmental Biology, November 1995, Elsevier

    Professor Dominik R Haudenschild

  86. The Role of Coiled-coil α-Helices and Disulfide Bonds in the Assembly and Stabilization of Cartilage Matrix Protein Subunits

    Article • Journal of Biological Chemistry, September 1995, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Dominik R Haudenschild

  87. Link protein is ubiquitously expressed in non-cartilaginous tissues where it enhances and stabilizes the interaction of proteoglycans with hyaluronic acid.

    Article • Journal of Biological Chemistry, July 1994, Elsevier

    Professor Dominik R Haudenschild