All Stories

  1. Unraveling the Bone Tissue Microenvironment in Chronic Lymphocytic Leukemia

    Article • Cancers, October 2023, MDPI AG

    Daniela de Totero

  2. A High Percentage of CD16+ Monocytes Correlates with the Extent of Bone Erosion in Chronic Lymphocytic Leukemia Patients: The Impact of Leukemic B Cells in Monocyte Differentiation and Osteoclast Maturation

    Article • Cancers, December 2022, MDPI AG

    Daniela de Totero

  3. Establishment and Characterization of a Novel Fibroblastic Cell Line (SCI13D) Derived from the Broncho-Alveolar Lavage of a Patient with Fibrotic Hypersensitivity Pneumonitis

    Article • Biomedicines, September 2021, MDPI AG

    Daniela de Totero

  4. Hepatocyte Growth Factor: A Microenvironmental Resource for Leukemic Cell Growth

    Article • International Journal of Molecular Sciences, January 2019, MDPI AG

    Daniela de Totero

  5. Microenvironmental regulation of the IL-23R/IL-23 axis overrides chronic lymphocytic leukemia indolence

    Article • Science Translational Medicine, February 2018, American Association for the Advancement of Science

    Claudio Tripodo, Daniela de Totero

  6. Functional Activation of Osteoclast Commitment in Chronic Lymphocytic Leukaemia: a Possible Role for RANK/RANKL Pathway

    Article • Scientific Reports, October 2017, Springer Science + Business Media

    Daniela de Totero

  7. Survival and Immunosuppression Induced by Hepatocyte Growth Factor in Chronic Lymphocytic Leukemia

    Article • Current Molecular Medicine, April 2017, Bentham Science Publishers

    Daniela de Totero

  8. Potentiation of cisplatin-induced antiproliferative and apoptotic activities by the antiarrhythmic drug procainamide hydrochloride

    Article • Pharmacological Reports, June 2016, Springer Science + Business Media

    Daniela de Totero

  9. Chronic lymphocytic leukemia nurse-like cells express hepatocyte growth factor receptor (c-MET) and indoleamine 2,3-dioxygenase and display features of immunosuppressive type 2 skewed macrophages

    Article • Haematologica, February 2014, Ferrata Storti Foundation (Haematologica)

    Claudio Tripodo, Daniela de Totero

  10. ABCB1 Structural Models, Molecular Docking, and Synthesis of New Oxadiazolothiazin-3-one Inhibitors

    Article • ACS Medicinal Chemistry Letters, May 2013, American Chemical Society (ACS)

    Daniela de Totero

  11. An interaction between hepatocyte growth factor and its receptor (c-MET) prolongs the survival of chronic lymphocytic leukemic cells through STAT3 phosphorylation: a potential role of mesenchymal cells in the disease

    Article • Haematologica, April 2011, Ferrata Storti Foundation (Haematologica)

    Professor Tullio Florio, Daniela de Totero

  12. Heterogeneous expression and function of IL-21R and susceptibility to IL-21−mediated apoptosis in follicular lymphoma cells

    Article • Experimental Hematology, May 2010, Elsevier

    Daniela de Totero

  13. The administration of demethyl fruticulin A from Salvia corrugata to mammalian cells lines induces “anoikis”, a special form of apoptosis

    Article • Phytomedicine, May 2010, Elsevier

    Daniela de Totero

  14. Inhibition of MDR1 activity and induction of apoptosis by analogues of nifedipine and diltiazem: an in vitro analysis

    Article • Investigational New Drugs, October 2009, Springer Science + Business Media

    Daniela de Totero

  15. Two-Step In Vivo Tumor Targeting by Biotin-Conjugated Antibodies and Superparamagnetic Nanoparticles Assessed by Magnetic Resonance Imaging at 1.5 T

    Article • Molecular Imaging and Biology, October 2009, Springer Science + Business Media

    Daniela de Totero

  16. Inhibition of MDR1 Activity in Vitro by a Novel Class of Diltiazem Analogues: Toward New Candidates

    Article • Journal of Medicinal Chemistry, December 2008, American Chemical Society (ACS)

    Daniela de Totero

  17. The opposite effects of IL-15 and IL-21 on CLL B cells correlate with differential activation of the JAK/STAT and ERK1/2 pathways

    Article • Blood, January 2008, American Society of Hematology

    Daniela de Totero

  18. Preparation and evaluation of nanoparticles made of chitosan or N-trimethyl chitosan and a cisplatin–alginate complex

    Article • Journal of Controlled Release, August 2007, Elsevier

    Daniela de Totero

  19. Role of IL-21 in immune-regulation and tumor immunotherapy

    Article • Cancer Immunology Immunotherapy, April 2007, Springer Science + Business Media

    Daniela de Totero

  20. Magnetic resonance imaging at 1.5 T with immunospecific contrast agent in vitro and in vivo in a xenotransplant model

    Article • Magnetic Resonance Materials in Physics Biology and Medicine, December 2006, Springer Science + Business Media

    Daniela de Totero

  21. Interleukin-21 receptor (IL-21R) is up-regulated by CD40 triggering and mediates proapoptotic signals in chronic lymphocytic leukemia B cells

    Article • Blood, May 2006, American Society of Hematology

    Daniela de Totero

  22. Resistance to CD95-mediated apoptosis of CD40-activated chronic lymphocytic leukemia B cells is not related to lack of DISC molecules expression

    Article • The Hematology Journal, January 2004, Springer Science + Business Media

    Daniela de Totero

  23. IL4 production and increased CD30 expression by a unique CD8+ T‐cell subset in B‐cell chronic lymphocytic leukaemia

    Article • British Journal of Haematology, March 1999, Wiley

    Daniela de Totero

  24. Targeting of saporin to Hodgkin's lymphoma cells by anti‐CD30 and anti‐CD25 bispecific antibodies

    Article • British Journal of Haematology, September 1998, Wiley

    Professor Rodolfo Ippoliti, Daniela de Totero

  25. Cellular Mechanisms of Exogenous Peptide Binding to HLA Class II Molecules in B Cells

    Article • Cellular Immunology, April 1994, Elsevier

    Daniela de Totero

  26. Immunotoxins containing saporin linked to different CD2 monoclonal antibodies: in vitro evaluation

    Article • British Journal of Haematology, January 1994, Wiley

    Daniela de Totero

  27. Cultured human NK cells express the Ki‐l/CD30 antigen

    Article • British Journal of Haematology, October 1993, Wiley

    Daniela de Totero

  28. Ber‐H2 (anti‐CD30)‐saporin immunotoxin: a new tool for the the treatment of Hodgkin's disease and CD30+ lymphoma: in vitro evaluation

    Article • British Journal of Haematology, June 1992, Wiley

    Daniela de Totero

  29. Polymorphism of the HLA-DPβ region detected by southern blot hybridization

    Article • Human Immunology, April 1990, Elsevier

    Daniela de Totero