All Stories

  1. Human Oncogene EWS::FLI1 Functions as a Pioneer Factor in Saccharomyces cerevisiae

    Article • October 2025, Cold Spring Harbor Laboratory Press

    Professor Cayetano Gonzalez

  2. Human EWS-FLI protein levels and neomorphic functions show a complex, function-specific dose–response relationship in Drosophila

    Article • Open Biology, July 2024, Royal Society Publishing

    Professor Cayetano Gonzalez

  3. TrxT and dhd are dispensable for Drosophila brain development but essential for l(3)mbt brain tumour growth

    Article • EMBO Reports, May 2024, Springer Science + Business Media

    Professor Cayetano Gonzalez

  4. The Drosophila cancer-germline, head-to-head gene pair TrxT and dhd is dispensable for normal brain development but plays a major role in l(3)mal...

    Article • November 2023, Cold Spring Harbor Laboratory Press

    Professor Cayetano Gonzalez

  5. Illuminati: a form of gene expression plasticity in Drosophila neural stem cells

    Article • Development, November 2022, The Company of Biologists

    Professor Cayetano Gonzalez

  6. Parafibromin governs cell polarity and centrosome assembly in Drosophila neural stem cells

    Article • PLoS Biology, October 2022, PLOS

    Hongyan Wang, Professor Cayetano Gonzalez

  7. Human EWS-FLI protein recapitulates in Drosophila the neomorphic functions that induce Ewing sarcoma tumorigenesis

    Article • PNAS Nexus, September 2022, Oxford University Press (OUP)

    Professor Cayetano Gonzalez

  8. Oxidative Stress Is Associated with Overgrowth in Drosophila l(3)mbt Mutant Imaginal Discs

    Article • Cells, August 2022, MDPI AG

    Professor Cayetano Gonzalez

  9. Structures of the germline-specific Deadhead and thioredoxin T proteins from Drosophila melanogaster reveal unique features among thioredoxins

    Article • IUCrJ, February 2021, International Union of Crystallography

    Professor Cayetano Gonzalez

  10. Centrosomes in asymmetric cell division

    Article • Current Opinion in Structural Biology, February 2021, Elsevier

    Professor Cayetano Gonzalez

  11. Context-Dependent Tumorigenic Effect of Testis-Specific Mitochondrial Protein Tiny Tim 2 in Drosophila Somatic Epithelia

    Article • Cells, August 2020, MDPI AG

    Professor Cayetano Gonzalez

  12. Structures of the germline-specific Deadhead and Thioredoxin T proteins fromDrosophila melanogasterreveal unique features among Thioredoxins

    Article • July 2020, Cold Spring Harbor Laboratory Press

    Professor Cayetano Gonzalez

  13. The histone code reader PHD finger protein 7 controls sex-linked disparities in gene expression and malignancy in Drosophila

    Article • Science Advances, August 2019, American Association for the Advancement of Science

    Professor Cayetano Gonzalez

  14. Centrobin is essential for C-tubule assembly and flagellum development in Drosophila melanogaster spermatogenesis

    Article • Journal of Cell Biology, April 2018, Rockefeller University Press

    Professor Cayetano Gonzalez

  15. Drosophila Larval Brain Neoplasms Present Tumour-Type Dependent Genome Instability

    Article • G3 Genes Genomes Genetics, February 2018, Genetics Society of America

    Professor Cayetano Gonzalez

  16. An in vivo genetic screen in Drosophila identifies the orthologue of human cancer/testis gene SPO11 among a network of targets to inhibit lethal(3)malignan...

    Article • Open Biology, August 2017, Royal Society Publishing

    Professor Cayetano Gonzalez

  17. Prefoldin and Pins synergistically regulate asymmetric division and suppress dedifferentiation

    Article • Scientific Reports, March 2016, Nature

    Professor Cayetano Gonzalez

  18. Arl2- and Msps-dependent microtubule growth governs asymmetric division

    Article • Journal of Cell Biology, March 2016, Rockefeller University Press

    Professor Cayetano Gonzalez

  19. The translational relevance ofDrosophilain drug discovery

    Article • EMBO Reports, February 2016, EMBO

    Professor Cayetano Gonzalez

  20. A last-minute decision

    Article • Nature, December 2015, Springer Science + Business Media

    Professor Cayetano Gonzalez

  21. Studying tumor growth in Drosophila using the tissue allograft method

    Article • Nature Protocols, September 2015, Springer Science + Business Media

    Professor Cayetano Gonzalez

  22. Loss of Centrobin Enables Daughter Centrioles to Form Sensory Cilia in Drosophila

    Article • Current Biology, August 2015, Elsevier

    Professor Cayetano Gonzalez

  23. Time-lapse recording of centrosomes and other organelles in Drosophila neuroblasts

    Article • January 2015, Elsevier

    Professor Cayetano Gonzalez

  24. Quantitative differences, qualitative outcomes

    Article • eLife, October 2014, eLife

    Professor Cayetano Gonzalez

  25. When fate follows age: unequal centrosomes in asymmetric cell division

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, July 2014, Royal Society Publishing

    Professor Cayetano Gonzalez

  26. The Brm-HDAC3-Erm repressor complex suppresses dedifferentiation in Drosophila type II neuroblast lineages

    Article • eLife, March 2014, eLife

    Hongyan Wang, Professor Cayetano Gonzalez, Dr Song Li, Dr Paul Robson, Dr Sherry S Aw

  27. Structure and Non-Structure of Centrosomal Proteins

    Article • PLOS One, May 2013, PLOS

    Professor Guillermo Montoya, Professor Cayetano Gonzalez

  28. Drosophila melanogaster: a model and a tool to investigate malignancy and identify new therapeutics

    Article • Nature Reviews Drug Discovery, February 2013, Springer Science + Business Media

    Professor Cayetano Gonzalez

  29. Centrobin controls mother–daughter centriole asymmetry in Drosophila neuroblasts

    Article • Nature Cell Biology, January 2013, Springer Science + Business Media

    Professor Cayetano Gonzalez

  30. On the inscrutable role of Inscuteable: structural basis and functional implications for the competitive binding of NuMA and Inscuteable to LGN

    Article • Open Biology, August 2012, Royal Society Publishing

    Professor Cayetano Gonzalez

  31. Drosophila Mgr, a Prefoldin subunit cooperating with von Hippel Lindau to regulate tubulin stability

    Article • Proceedings of the National Academy of Sciences, March 2012, Proceedings of the National Academy of Sciences

    Professor Cayetano Gonzalez

  32. Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics

    Article • BMC Cancer, January 2012, Springer Science + Business Media

    Professor Cayetano Gonzalez

  33. Synergism between altered cortical polarity and the PI3K/TOR pathway in the suppression of tumour growth

    Article • EMBO Reports, December 2011, EMBO

    Professor Cayetano Gonzalez

  34. An Ana2/Ctp/Mud Complex Regulates Spindle Orientation in Drosophila Neuroblasts

    Article • Developmental Cell, September 2011, Elsevier

    Professor Cayetano Gonzalez, Dr Song Li

  35. Drosophila neuroblasts retain the daughter centrosome

    Article • Nature Communications, March 2011, Springer Science + Business Media

    Professor Cayetano Gonzalez

  36. Ectopic Expression of Germline Genes Drives Malignant Brain Tumor Growth in Drosophila

    Article • Science, December 2010, American Association for the Advancement of Science

    Professor Cayetano Gonzalez

  37. Interplay between the Transcription Factor Zif and aPKC Regulates Neuroblast Polarity and Self-Renewal

    Article • Developmental Cell, November 2010, Elsevier

    Professor Cayetano Gonzalez

  38. Neural stem cells: the need for a proper orientation

    Article • Current Opinion in Genetics & Development, August 2010, Elsevier

    Professor Cayetano Gonzalez

  39. Time‐Lapse Imaging of Embryonic Neural Stem Cell Division in Drosophila by Two‐Photon Microscopy

    Article • Current Protocols in Stem Cell Biology, June 2010, Wiley

    Professor Cayetano Gonzalez

  40. The interphase microtubule aster is a determinant of asymmetric division orientation inDrosophilaneuroblasts

    Article • Journal of Cell Biology, March 2010, Rockefeller University Press

    Professor Cayetano Gonzalez

  41. Biased segregation of DNA and centrosomes — moving together or drifting apart?

    Article • Nature Reviews Molecular Cell Biology, November 2009, Springer Science + Business Media

    Professor Cayetano Gonzalez

  42. Spindle alignment is achieved without rotation after the first cell cycle in Drosophila embryonic neuroblasts

    Article • Development, September 2009, The Company of Biologists

    Professor Cayetano Gonzalez

  43. Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling

    Article • Nature Genetics, September 2009, Springer Science + Business Media

    Professor Cayetano Gonzalez, Dr Giacomo Cavalli

  44. 08-P016 Maintenance of the orientation of polarity in Drosophila larval brain neuroblasts

    Article • Mechanisms of Development, August 2009, Elsevier

    Professor Cayetano Gonzalez

  45. S07-05 Neural stem cell polarity and malignant growth in Drosophila

    Article • Mechanisms of Development, August 2009, Elsevier

    Professor Cayetano Gonzalez

  46. Below the Convergence

    Article • Current Biology, April 2009, Elsevier

    Professor Cayetano Gonzalez

  47. Centrosome function during stem cell division: the devil is in the details

    Article • Current Opinion in Cell Biology, December 2008, Elsevier

    Professor Cayetano Gonzalez

  48. Drosophila asymmetric division, polarity and cancer

    Article • Oncogene, November 2008, Springer Science + Business Media

    Professor Cayetano Gonzalez

  49. Centrosome Dysfunction in Drosophila Neural Stem Cells Causes Tumors that Are Not Due to Genome Instability

    Article • Current Biology, August 2008, Elsevier

    Professor Cayetano Gonzalez

  50. Cayetano Gonzalez

    Article • Current Biology, January 2008, Elsevier

    Professor Cayetano Gonzalez

  51. Spermatocyte cytokinesis requires rapid membrane addition mediated by ARF6 on central spindle recycling endosomes

    Article • Development, December 2007, The Company of Biologists

    Professor Cayetano Gonzalez

  52. Asterless Is a Centriolar Protein Required for Centrosome Function and Embryo Development in Drosophila

    Article • Current Biology, October 2007, Elsevier

    Professor Cayetano Gonzalez

  53. Spindle orientation, asymmetric division and tumour suppression in Drosophila stem cells

    Article • Nature Reviews Genetics, June 2007, Springer Science + Business Media

    Professor Cayetano Gonzalez

  54. Functionally Unequal Centrosomes Drive Spindle Orientation in Asymmetrically Dividing Drosophila Neural Stem Cells

    Article • Developmental Cell, March 2007, Elsevier

    Professor Cayetano Gonzalez

  55. Localized transfection with magnetic beads coated with PCR products and other nucleic acids

    Article • Nature Protocols, June 2006, Springer Science + Business Media

    Professor Cayetano Gonzalez

  56. Connecting Cancer to the Asymmetric Division of Stem Cells

    Article • Cell, March 2006, Elsevier

    Professor Cayetano Gonzalez

  57. Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster

    Article • Nature Genetics, September 2005, Springer Science + Business Media

    Professor Cayetano Gonzalez

  58. Structure and microtubule-nucleation activity of isolated Drosophila embryo centrosomes characterized by whole mount scanning and transmission electron microscopy

    Article • Histochemistry and Cell Biology, August 2005, Springer Science + Business Media

    Professor Cayetano Gonzalez

  59. Localized transfection on arrays of magnetic beads coated with PCR products

    Article • Nature Chemical Biology, January 2005, Springer Science + Business Media

    Professor Cayetano Gonzalez

  60. Contribution of Noncentrosomal Microtubules to Spindle Assembly in Drosophila Spermatocytes

    Article • PLoS Biology, January 2004, PLOS

    Professor Cayetano Gonzalez

  61. γ-Tubulin function during female germ-cell development and oogenesis in Drosophila

    Article • Proceedings of the National Academy of Sciences, August 2003, Proceedings of the National Academy of Sciences

    Professor Cayetano Gonzalez

  62. Cell Division: The Place and Time of Cytokinesis

    Article • Current Biology, April 2003, Elsevier

    Professor Cayetano Gonzalez

  63. Drosophila dd4 mutants reveal that gammaTuRC is required to maintain juxtaposed half spindles in spermatocytes

    Article • Journal of Cell Science, January 2003, The Company of Biologists

    Professor Cayetano Gonzalez

  64. Cdc37 is essential for chromosome segregation and cytokinesis in higher eukaryotes

    Article • The EMBO Journal, October 2002, Wiley

    Professor Cayetano Gonzalez

  65. Computer-aided design of a PDZ domain to recognize new target sequences

    Article • Nature Structural Biology, June 2002, Springer Science + Business Media

    Professor Cayetano Gonzalez

  66. Miranda, a protein involved in neuroblast asymmetric division, is associated with embryonic centrosomes of Drosophila melanogaster

    Article • Biology of the Cell, February 2002, Wiley

    Professor Cayetano Gonzalez

  67. Organized microtubule arrays in γ-tubulin-depleted Drosophila spermatocytes

    Article • Current Biology, November 2001, Elsevier

    Professor Cayetano Gonzalez

  68. Requirement of Hsp90 for centrosomal function reflects its regulation of Polo kinase stability

    Article • The EMBO Journal, June 2001, Wiley

    Professor Cayetano Gonzalez

  69. Patterns of Cell Division and Expression of Asymmetric Cell Fate Determinants in Postembryonic Neuroblast Lineages of Drosophila

    Article • Developmental Biology, February 2001, Elsevier

    Professor Cayetano Gonzalez

  70. Dominant-negative mutant dynein allows spontaneous centrosome assembly, uncouples chromosome and centrosome cycles

    Article • Current Biology, January 2001, Elsevier

    Professor Cayetano Gonzalez

  71. Light, flies and cell division

    Article • EMBO Reports, November 2000, EMBO

    Professor Cayetano Gonzalez

  72. Vaccinia virus infection disrupts microtubule organization and centrosome function

    Article • The EMBO Journal, August 2000, Springer Science + Business Media

    Professor Cayetano Gonzalez

  73. Visualizing the spindle checkpoint inDrosophilaspermatocytes

    Article • EMBO Reports, July 2000, EMBO

    Professor Cayetano Gonzalez

  74. Protein traps: using intracellular localization for cloning

    Article • Trends in Cell Biology, April 2000, Elsevier

    Professor Cayetano Gonzalez

  75. Cytological characterisation of the mutant phenotypes produced during early embryogenesis by null and loss-of-function alleles of the γTub37C gene in Drosophila

    Article • Journal of Cell Science, March 1999, The Company of Biologists

    Professor Cayetano Gonzalez

  76. Interactions between mgr , asp , and polo : asp function modulated by polo and needed to maintain the poles of monopolar and bipolar spindles

    Article • Chromosoma, December 1998, Springer Science + Business Media

    Professor Cayetano Gonzalez

  77. Microinjection of Drosophila Eggs

    Article • January 1998, Springer Science + Business Media

    Professor Cayetano Gonzalez

  78. TheDrosophilaGeneabnormal spindleEncodes a Novel Microtubule-associated Protein That Associates with the Polar Regions of the Mitotic Spindle

    Article • Journal of Cell Biology, May 1997, Rockefeller University Press

    Professor Cayetano Gonzalez

  79. Essential role for gamma -tubulin in the acentriolar female meiotic spindle of Drosophila

    Article • The EMBO Journal, April 1997, Wiley

    Professor Cayetano Gonzalez

  80. 16 Methods in Drosophila Cell Cycle Biology

    Article • January 1997, Elsevier

    Professor Cayetano Gonzalez

  81. Mutations in New Cell Cycle Genes That Fail to Complement a Multiply Mutant Third Chromosome of Drosophila

    Article • Genetics, November 1996, Oxford University Press (OUP)

    Professor Cayetano Gonzalez

  82. Transposable elements map in a conserved pattern of distribution extending from beta-heterochromatin to centromeres in Drosophila melanogaster

    Article • Chromosoma, August 1995, Springer Science + Business Media

    Professor Cayetano Gonzalez

  83. Gamma-tubulin is required for the structure and function of the microtubule organizing centre in Drosophila neuroblasts.

    Article • The EMBO Journal, January 1995, Springer Science + Business Media

    Professor Cayetano Gonzalez

  84. Molecular analysis of ribosomal DNA from the aphid Amphorophora idaei and an associated fungal organism

    Article • Insect Molecular Biology, August 1994, Wiley

    Professor Cayetano Gonzalez

  85. Cell Cycle Genes of Drosophila

    Article • January 1994, Elsevier

    Professor Cayetano Gonzalez

  86. The Centrosome

    Article • Scientific American, June 1993, Springer Science + Business Media

    Professor Cayetano Gonzalez, Professor Jordan Raff

  87. Cell type-specific gene expression in the Drosophila melanogaster male accessory gland

    Article • Mechanisms of Development, July 1992, Elsevier

    Professor Cayetano Gonzalez

  88. Regulation of the G1-S transition in postembryonic neuronal precursors by axon ingrowth

    Article • Nature, January 1992, Springer Science + Business Media

    Professor Cayetano Gonzalez

  89. Applications of confocal laser scanning microscopy

    Article • Trends in Cell Biology, December 1991, Elsevier

    Professor Cayetano Gonzalez

  90. polo encodes a protein kinase homolog required for mitosis in Drosophila.

    Article • Genes & Development, December 1991, Cold Spring Harbor Laboratory Press

    Professor Cayetano Gonzalez

  91. Dosage dependence of maternal contribution to somatic cell division in Drosophila melanogaster

    Article • Development, December 1991, The Company of Biologists

    Professor Cayetano Gonzalez

  92. The spindle is required for the process of sister chromatid separation in Drosophila neuroblasts

    Article • Experimental Cell Research, January 1991, Elsevier

    Professor Cayetano Gonzalez

  93. Cyclical Changes in the Subcellular Distribution of Proteins Essential for Mitosis during Embryogenesis in Drosophila

    Article • Cold Spring Harbor Symposia on Quantitative Biology, January 1991, Cold Spring Harbor Laboratory Press

    Professor Cayetano Gonzalez

  94. The A- and B-type cyclins of Drosophila are accumulated and destroyed in temporally distinct events that define separable phases of the G2-M transition.

    Article • The EMBO Journal, August 1990, Springer Science + Business Media

    Professor Cayetano Gonzalez

  95. Relationship between chromosome content and nuclear diameter in early spermatids ofDrosophila melanogaster

    Article • Genetics Research, December 1989, Hindawi Publishing Corporation

    Professor Cayetano Gonzalez

  96. Transcripts of one of two Drosophila cyclin genes become localized in pole cells during embryogenesis

    Article • Nature, March 1989, Springer Science + Business Media

    Professor Cayetano Gonzalez

  97. Functional monopolar spindles caused by mutation in MGR, a cell division gene of Drosophila melanogaster

    Article • Journal of Cell Science, January 1988, The Company of Biologists

    Professor Cayetano Gonzalez

  98. Towards the genetic dissection of mitosis inDrosophila

    Article • BioEssays, November 1987, Wiley

    Professor Cayetano Gonzalez

  99. Time-Lapse Imaging of Male Meiosis by Phase-Contrast and Fluorescence Microscopy

    Article • Springer Science + Business Media

    Professor Cayetano Gonzalez