All Stories

  1. The conserved Spd-2/CEP192 domain adopts a unique protein fold to promote centrosome scaffold assembly

    Article • Science Advances, March 2025, American Association for the Advancement of Science

    Professor Jordan Raff

  2. Centrioles generate two scaffolds with distinct biophysical properties to build mitotic centrosomes

    Article • Science Advances, February 2025, American Association for the Advancement of Science

    Professor Jordan Raff

  3. Centrioles generate two scaffolds with distinct biophysical properties to build mitotic centrosomes

    Article • April 2024, Cold Spring Harbor Laboratory Press

    Professor Jordan Raff

  4. Regulation of centrosome size by the cell-cycle oscillator in Drosophila embryos

    Article • The EMBO Journal, January 2024, Springer Science + Business Media

    Professor Jordan Raff

  5. A simple Turing reaction–diffusion model explains how PLK4 breaks symmetry during centriole duplication and assembly

    Article • PLoS Biology, November 2023, PLOS

    Professor Jordan Raff

  6. Cdk/Cyclin activity helps set mitotic centrosome size by influencing the centrosome growth rate and growth period

    Article • April 2023, Cold Spring Harbor Laboratory Press

    Professor Jordan Raff

  7. A simple Turing reaction-diffusion model can explain how mother centrioles break symmetry to generate a single daughter

    Article • February 2023, Cold Spring Harbor Laboratory Press

    Professor Jordan Raff

  8. Centriole growth is limited by the Cdk/Cyclin-dependent phosphorylation of Ana2/STIL

    Article • Journal of Cell Biology, July 2022, Rockefeller University Press

    Professor Jordan Raff

  9. Centriole distal-end proteins CP110 and Cep97 influence centriole cartwheel growth at the proximal end

    Article • Journal of Cell Science, July 2022, The Company of Biologists

    Professor Jordan Raff

  10. Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly

    Article • The EMBO Journal, May 2022, Springer Science + Business Media

    Professor Jordan Raff

  11. Centriole growth is not limited by a finite pool of components, but is limited by the Cdk1/Cyclin-dependent phosphorylation of Ana2/STIL

    Article • February 2022, Cold Spring Harbor Laboratory Press

    Professor Jordan Raff

  12. Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly

    Article • October 2021, Cold Spring Harbor Laboratory Press

    Professor Jordan Raff

  13. Ana1 helps recruit Polo to centrioles to promote mitotic PCM assembly and centriole elongation

    Article • Journal of Cell Science, July 2021, The Company of Biologists

    Professor Jordan Raff

  14. Centriole distal-end proteins CP110 and Cep97 influence centriole cartwheel growth at the proximal-end

    Article • July 2021, Cold Spring Harbor Laboratory Press

    Professor Jordan Raff

  15. Drosophila Sas-6, Ana2 and Sas-4 self-organise into macromolecular structures that can be used to probe centriole and centrosome assembly

    Article • Journal of Cell Science, June 2020, The Company of Biologists

    Professor Jordan Raff

  16. Evidence that a positive feedback loop drives centrosome maturation in fly embryos

    Article • eLife, September 2019, eLife

    Professor Jordan Raff

  17. A free-running oscillator times and executes centriole biogenesis

    Article • January 2019, Cold Spring Harbor Laboratory Press

    Professor Jordan Raff

  18. Lessons learned: eight years at the helm of Biology Open

    Article • Biology Open, August 2018, The Company of Biologists

    Professor Jordan Raff

  19. A positive feedback loop drives centrosome maturation in flies

    Article • July 2018, Cold Spring Harbor Laboratory Press

    Professor Jordan Raff

  20. A homeostatic clock sets daughter centriole size in flies

    Article • Journal of Cell Biology, March 2018, Rockefeller University Press

    Professor Jordan Raff

  21. Drosophila PLP assembles pericentriolar clouds that promote centriole stability, cohesion and MT nucleation

    Article • PLoS Genetics, February 2018, PLOS

    Professor Jordan Raff

  22. Happy 5th Birthday Biology Open

    Article • Biology Open, July 2017, The Company of Biologists

    Professor Jordan Raff

  23. Drosophila PLP forms centriolar-clouds that promote centriole stability, cohesion and MT nucleation

    Article • July 2017, Cold Spring Harbor Laboratory Press

    Professor Jordan Raff

  24. Structural Basis for Mitotic Centrosome Assembly in Flies

    Article • Cell, June 2017, Elsevier

    Professor Jordan Raff

  25. A key centriole assembly interaction interface between human Plk4 and STIL appears to not be conserved in flies

    Article • Biology Open, February 2017, The Company of Biologists

    Professor Jordan Raff

  26. Drosophilasensory cilia lacking MKS-proteins exhibit striking defects in development but only subtle defects in adults

    Article • Journal of Cell Science, August 2016, The Company of Biologists

    Professor Jordan Raff

  27. DrosophilaAna1 is required for centrosome assembly and centriole elongation

    Article • Journal of Cell Science, May 2016, The Company of Biologists

    Professor Jordan Raff

  28. A molecular mechanism of mitotic centrosome assembly in Drosophila

    Article • eLife, August 2014, eLife

    Professor Jordan Raff

  29. Asterless Licenses Daughter Centrioles to Duplicate for the First Time in Drosophila Embryos

    Article • Current Biology, June 2014, Elsevier

    Professor Jordan Raff

  30. Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly

    Article • eLife, September 2013, eLife

    Yao Liang Wong, Professor Jordan Raff, Susan M Lea

  31. SAS-6 oligomerization: the key to the centriole?

    Article • Nature Chemical Biology, September 2011, Springer Science + Business Media

    Susan M Lea, Professor Jordan Raff

  32. Centrioles Regulate Centrosome Size by Controlling the Rate of Cnn Incorporation into the PCM

    Article • Current Biology, December 2010, Elsevier

    Professor Jordan Raff

  33. Cnn Dynamics Drive Centrosome Size Asymmetry to Ensure Daughter Centriole Retention in Drosophila Neuroblasts

    Article • Current Biology, December 2010, Elsevier

    Professor Jordan Raff

  34. DSas-6 and Ana2 Coassemble into Tubules to Promote Centriole Duplication and Engagement

    Article • Developmental Cell, December 2010, Elsevier

    Professor Jordan Raff

  35. Centrioles, Centrosomes, and Cilia in Health and Disease

    Article • Cell, November 2009, Elsevier

    Professor Jordan Raff

  36. A Genome-Wide RNAi Screen to Dissect Centriole Duplication and Centrosome Maturation in Drosophila

    Article • PLoS Biology, September 2008, PLOS

    Professor Jordan Raff

  37. Drosophila Spd-2 Recruits PCM to the Sperm Centriole, but Is Dispensable for Centriole Duplication

    Article • Current Biology, October 2007, Elsevier

    Professor Jordan Raff

  38. From Stem Cell to Embryo without Centrioles

    Article • Current Biology, September 2007, Elsevier

    Professor Jordan Raff

  39. Overexpressing Centriole-Replication Proteins In Vivo Induces Centriole Overduplication and De Novo Formation

    Article • Current Biology, May 2007, Elsevier

    Professor Jordan Raff

  40. Flies without Centrioles

    Article • Cell, June 2006, Elsevier

    Professor Jordan Raff

  41. Centrosomes in a Developing Organism: Lessons from Drosophila

    Article • June 2005, Wiley

    Professor Jordan Raff

  42. Q & A

    Article • Current Biology, December 2004, Elsevier

    Professor Jordan Raff

  43. Genome maintenance

    Article • Nature, May 2003, Springer Science + Business Media

    Professor Jordan Raff

  44. Centrosomes: Central no more?

    Article • Current Biology, March 2001, Elsevier

    Professor Jordan Raff

  45. Centrosomes have a role in regulating the destruction of cyclin B in early Drosophila embryos

    Article • Current Biology, November 2000, Elsevier

    Professor Jordan Raff

  46. D-TACC: a novel centrosomal protein required for normal spindle function in the early Drosophila embryo

    Article • The EMBO Journal, January 2000, Wiley

    Professor Jordan Raff

  47. Why don't people like me?

    Article • Current Biology, November 1999, Elsevier

    Professor Jordan Raff

  48. Nuclear migration: The missing (L) UNC?

    Article • Current Biology, September 1999, Elsevier

    Professor Jordan Raff

  49. Centrosomes and microtubules: wedded with a ring

    Article • Trends in Cell Biology, July 1996, Elsevier

    Professor Jordan Raff

  50. Mitosis in motion

    Article • Trends in Cell Biology, January 1996, Elsevier

    Professor Jordan Raff

  51. The Centrosome

    Article • Scientific American A Matter of Time, June 1993, Springer Science + Business Media

    Professor Cayetano Gonzalez, Professor Jordan Raff

  52. Centrosomes, and not nuclei, initiate pole cell formation in Drosophila embryos

    Article • Cell, May 1989, Elsevier

    Professor Jordan Raff