All Stories

  1. Echocardiographic Imaging in Conscious, Unsedated Sheep: A Novel Approach Enabling Apical Views for Advanced Cardiac Assessment

    Article • AJP Heart and Circulatory Physiology, November 2025, American Physiological Society

    Professor Andrew Trafford

  2. Suppression of premature ventricular complexes with the PDE5 inhibitor sildenafil: First clinical experience

    Article • Experimental Physiology, September 2025, Wiley

    Professor Andrew Trafford

  3. The air pollutant phenanthrene disrupts calcium cycling and alters repolarization in female sheep ventricular cardiomyocytes

    Article • Physiological Reports, August 2025, Wiley

    Professor Andrew Trafford

  4. A refined, minimally invasive, reproducible ovine ischaemia–reperfusion–infarction model using implantable defibrillators: Methodology and validation

    Article • Experimental Physiology, December 2024, Wiley

    Professor Andrew Trafford

  5. Brief response to Terrar

    Article • The Journal of Physiology, November 2024, Wiley

    Professor Andrew Trafford

  6. Maladaptive cardiomyocyte calcium handling in adult offspring of hypoxic pregnancy: protection by antenatal maternal melatonin

    Article • The Journal of Physiology, November 2024, Wiley

    Professor Andrew Trafford

  7. Calcium flux balance in the heart: how many of the important questions are really unanswered?

    Article • The Journal of Physiology, November 2024, Wiley

    Professor Andrew Trafford

  8. Acute sildenafil administration reduces susceptibility to induced atrial fibrillation in sheep

    Article • September 2024, Cold Spring Harbor Laboratory Press

    Professor Andrew Trafford

  9. Restoring Atrial T-Tubules Augments Systolic Ca Upon Recovery From Heart Failure

    Article • Circulation Research, September 2024, Wolters Kluwer Health

    Professor Andrew Trafford

  10. BS45 Transcriptomic analysis of differential ventricular gene expression patterns in response to phosphodiesterase 5 inhibition in heart failure

    Article • May 2024, BMJ

    Professor Andrew Trafford

  11. On the role of dysferlin in striated muscle: membrane repair, t‐tubules and Ca2+ handling

    Article • The Journal of Physiology, April 2024, Wiley

    Professor Andrew Trafford

  12. Atrial t-tubules adopt a specialist developmental state while alterations to Ca2+buffering maintain systolic Ca2+during postnatal development

    Article • October 2023, Cold Spring Harbor Laboratory Press

    Professor Andrew Trafford

  13. A novel minimally invasive and reproducible large animal ischaemia-reperfusion-infarction model: methodology and model validation

    Article • March 2023, Cold Spring Harbor Laboratory Press

    Professor Andrew Trafford

  14. Peptide location fingerprinting identifies species- and tissue-conserved structural remodelling of proteins as a consequence of ageing and disease

    Article • Matrix Biology, December 2022, Elsevier

    Professor Andrew Trafford

  15. Enhanced calcium release at specialised surface sites compensates for reduced t-tubule density in neonatal sheep atrial myocytes

    Article • Journal of Molecular and Cellular Cardiology, December 2022, Elsevier

    Professor Andrew Trafford

  16. Postnatal cardiovascular morbidity following preterm pre-eclampsia: An observational study

    Article • Pregnancy Hypertension, December 2022, Elsevier

    Professor Andrew Trafford

  17. Cardiomyocyte-specific loss of plasma membrane calcium ATPase 1 impacts cardiac rhythm and is associated with ventricular repolarisation dysfunction

    Article • Journal of Molecular and Cellular Cardiology, November 2022, Elsevier

    Professor Andrew Trafford

  18. Serial block face scanning electron microscopy reveals region-dependent remodelling of transverse tubules post-myocardial infarction

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, October 2022, Royal Society Publishing

    Professor Andrew Trafford

  19. Chronic developmental hypoxia alters mitochondrial oxidative capacity and reactive oxygen species production in the fetal rat heart in a sex‐dependent manner

    Article • Journal of Pineal Research, August 2022, Wiley

    Professor Andrew Trafford

  20. Alkaline nucleoplasm facilitates contractile gene expression in the mammalian heart

    Article • Basic Research in Cardiology, March 2022, Springer Science + Business Media

    Dr Pawel Swietach, Professor Andrew Trafford

  21. Interaction of background Ca2+ influx, sarcoplasmic reticulum threshold and heart failure in determining propensity for Ca2+ waves in sheep heart

    Article • The Journal of Physiology, March 2022, Wiley

    Professor Andrew Trafford

  22. Cardiac Transverse Tubules in Physiology and Heart Failure

    Article • Annual Review of Physiology, February 2022, Annual Reviews

    Professor Andrew Trafford

  23. Disordered yet functional atrial t-tubules on recovery from heart failure

    Article • October 2021, Cold Spring Harbor Laboratory Press

    Professor Andrew Trafford

  24. Maternal melatonin: Effective intervention against developmental programming of cardiovascular dysfunction in adult offspring of complicated pregnancy

    Article • Journal of Pineal Research, October 2021, Wiley

    Professor Andrew Trafford

  25. Peptide Location Fingerprinting Reveals Tissue Region-Specific Differences in Protein Structures in an Ageing Human Organ

    Article • International Journal of Molecular Sciences, September 2021, MDPI AG

    Professor Andrew Trafford

  26. PDE5 Inhibition Suppresses Ventricular Arrhythmias by Reducing SR Ca 2+ Content

    Article • Circulation Research, September 2021, Wolters Kluwer Health

    Professor Andrew Trafford

  27. Electrophysiological and Proarrhythmic Effects of Hydroxychloroquine Challenge in Guinea-Pig Hearts

    Article • ACS Pharmacology & Translational Science, August 2021, American Chemical Society (ACS)

    Professor Andrew Trafford

  28. Transverse-tubule remodelling in remote and border regions following myocardial infarction

    Article • July 2021, Royal Microscopical Society

    Professor Andrew Trafford

  29. Optimising Large Animal Models of Sustained Atrial Fibrillation: Relevance of the Critical Mass Hypothesis

    Article • Frontiers in Physiology, June 2021, Frontiers

    Professor Andrew Trafford

  30. Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia

    Article • Nature Communications, April 2021, Springer Science + Business Media

    Professor Andrew Trafford

  31. Response to correspondence on “Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation”

    Article • Genome Biology, April 2021, Springer Science + Business Media

    Professor Andrew Trafford

  32. Substrate for the Myocardial Inflammation–Heart Failure Hypothesis Identified Using Novel USPIO Methodology

    Article • JACC Cardiovascular Imaging, February 2021, Elsevier

    Professor Andrew Trafford

  33. Sex-dependent effects of developmental hypoxia on cardiac mitochondria from adult murine offspring

    Article • Free Radical Biology and Medicine, January 2021, Elsevier

    Professor Andrew Trafford

  34. Postnatal Enalapril to Improve Cardiovascular Function Following Preterm Preeclampsia (PICk-UP):

    Article • Hypertension, December 2020, Wolters Kluwer Health

    Professor Andrew Trafford

  35. Non-ischemic Heart Preservation via Hypothermic Cardioplegic Perfusion Induces Immunodepletion of Donor Hearts Resulting in Diminished Graft Infiltration Following Transplantation

    Article • Frontiers in Immunology, July 2020, Frontiers

    William R Critchley, Professor Andrew Trafford

  36. The Control of Diastolic Calcium in the Heart

    Article • Circulation Research, January 2020, Wolters Kluwer Health

    Professor Andrew Trafford

  37. Chronic vagal nerve stimulation has no effect on tachycardia‐induced heart failure progression or excitation–contraction coupling

    Article • Physiological Reports, January 2020, Wiley

    Professor Andrew Trafford

  38. Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation

    Article • Genome Biology, August 2019, Springer Science + Business Media

    Professor Andrew Trafford

  39. Phosphodiesterase 5 inhibition improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure

    Article • Scientific Reports, May 2019, Springer Science + Business Media

    Professor Andrew Trafford

  40. Increased Vulnerability to Atrial Fibrillation Is Associated With Increased Susceptibility to Alternans in Old Sheep

    Article • Journal of the American Heart Association, December 2018, Wolters Kluwer Health

    Professor Andrew Trafford

  41. Calcium in the Pathophysiology of Atrial Fibrillation and Heart Failure

    Article • Frontiers in Physiology, October 2018, Frontiers

    Professor Andrew Trafford

  42. Phosphodiesterase-5 inhibitors and the heart: compound cardioprotection?

    Article • Heart, March 2018, BMJ

    Professor Andrew Trafford

  43. Physiology and patho-physiology of the cardiac transverse tubular system

    Article • Current Opinion in Physiology, February 2018, Elsevier

    Professor Andrew Trafford

  44. Phosphodiesterase-5 inhibitors as novel cardioprotective agents: have we reached threshold for large-scale clinical trials?

    Article • Heart, October 2017, BMJ

    Professor Andrew Trafford

  45. Letter by Pearman et al. regarding article “Effect of botulinum toxin on inducibility and maintenance of atrial fibrillation in ovine myocardial tissue”

    Article • Pacing and Clinical Electrophysiology, September 2017, Wiley

    Katharine Dibb, Professor Andrew Trafford

  46. Understanding why cardiac function is altered by ageing

    Article • The Journal of Physiology, September 2017, Wiley

    Katharine Dibb, Professor Andrew Trafford

  47. A computational model of spatio-temporal cardiac intracellular calcium handling with realistic structure and spatial flux distribution from sarcoplasmic reticulum and t-tubule reconstructions

    Article • PLoS Computational Biology, August 2017, PLOS

    Professor Andrew Trafford

  48. Calcium and Excitation-Contraction Coupling in the Heart

    Article • Circulation Research, July 2017, Wolters Kluwer Health

    Professor Andrew Trafford

  49. Vagal Nerve Stimulation for the Treatment of Heart Failure

    Article • January 2017, Springer Science + Business Media

    Professor Andrew Trafford

  50. Frequency-modulated atomic force microscopy localises viscoelastic remodelling in the ageing sheep aorta

    Article • Journal of the Mechanical Behavior of Biomedical Materials, December 2016, Elsevier

    Brian Derby, Professor Andrew Trafford

  51. Phosphodiesterase type-5 inhibitor use in type 2 diabetes is associated with a reduction in all-cause mortality

    Article • Heart, July 2016, BMJ

    Professor Andrew Trafford

  52. Aging and the cardiac collagen matrix: Novel mediators of fibrotic remodelling

    Article • Journal of Molecular and Cellular Cardiology, April 2016, Elsevier

    Professor Andrew Trafford

  53. Omega-3 fatty acids do not alter P-wave parameters in electrocardiogram or expression of atrial connexins in patients undergoing coronary artery bypass surgery

    Article • EP Europace, February 2016, European Society of Cardiology

    Professor Andrew Trafford

  54. Temporal Development of Autonomic Dysfunction in Heart Failure: Effects of Age in an Ovine Rapid-pacing Model

    Article • The Journals of Gerontology Series A, December 2015, Oxford University Press (OUP)

    Professor Andrew Trafford

  55. A model model: a commentary on DiFrancesco and Noble (1985) 'A model of cardiac electrical activity incorporating ionic pumps and concentration changes'

    Article • Philosophical Transactions of the Royal Society B Biological Sciences, March 2015, Royal Society Publishing

    Professor Andrew Trafford

  56. Three-Dimensional Structure of the Intercalated Disc Reveals Plicate Domain and Gap Junction Remodeling in Heart Failure

    Article • Biophysical Journal, February 2015, Elsevier

    Professor Andrew Trafford

  57. Perturbed atrial calcium handling in an ovine model of heart failure: Potential roles for reductions in the L-type calcium current

    Article • Journal of Molecular and Cellular Cardiology, February 2015, Elsevier

    Professor Andrew Trafford

  58. MAPS; acute safety data of the St Jude accent - tendril IPG system during prolonged max power CMR scanning

    Article • Journal of Cardiovascular Magnetic Resonance, January 2015, Springer Science + Business Media

    Professor Andrew Trafford

  59. Sildenafil protects against heart attacks in patients with type II diabetes

    Article • Artery Research, December 2014, Elsevier

    Professor Andrew Trafford

  60. The protein AmpII (BIN1) regulates transverse tubules in the heart

    Article • Circulation Research, October 2014, Wolters Kluwer Health

    Professor Andrew Trafford

  61. Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes

    Article • Cardiovascular Research, September 2014, European Society of Cardiology

    Professor Andrew Trafford

  62. Direct measurements of SR free Ca reveal the mechanism underlying the transient effects of RyR potentiation under physiological conditions

    Article • Cardiovascular Research, June 2014, European Society of Cardiology

    Professor Andrew Trafford

  63. 185 Remodelling of Specialised Domains of the Sarcolemma in Heart Failure; Reorganisation of the Intercalted Disc Revealed by Nano-scale Imaging

    Article • Heart, May 2014, BMJ

    Professor Andrew Trafford

  64. An Induced Pluripotent Stem Cell Model of Hypoplastic Left Heart Syndrome (HLHS) Reveals Multiple Expression and Functional Differences in HLHS-Derived Cardiac Myocytes

    Article • Stem Cells Translational Medicine, March 2014, Wiley

    Professor Andrew Trafford

  65. EMC 2013

    Article • Journal of Muscle Research and Cell Motility, February 2014, Springer Science + Business Media

    Professor Andrew Trafford

  66. Human junctophilin-2 undergoes a structural rearrangement upon binding PtdIns(3,4,5)P3and the S101R mutation identified in hypertrophic cardiomyopathy obviates this response

    Article • Biochemical Journal, December 2013, Portland Press Ltd.

    Professor Andrew Trafford

  67. Sarcoplasmic Reticulum Ca-ATPase and Heart Failure 20 Years Later

    Article • Circulation Research, September 2013, Wolters Kluwer Health

    Professor Andrew Trafford

  68. Three-Dimensional Reconstruction of Cardiac Sarcoplasmic Reticulum Reveals a Continuous Network Linking Transverse-Tubules: This Organization Is Perturbed in Heart Failure

    Article • Circulation Research, September 2013, Wolters Kluwer Health

    Professor Andrew Trafford

  69. A functional role for transverse (t-) tubules in the atria

    Article • Journal of Molecular and Cellular Cardiology, May 2013, Elsevier

    Professor Andrew Trafford

  70. Calcium flux balance in the heart

    Article • Journal of Molecular and Cellular Cardiology, May 2013, Elsevier

    Professor Andrew Trafford

  71. Calcium signalling microdomains and the t-tubular system in atrial mycoytes: potential roles in cardiac disease and arrhythmias

    Article • Cardiovascular Research, February 2013, European Society of Cardiology

    Professor Andrew Trafford

  72. Effects of phosphodiesterase type 5A inhibition on intracellular calcium handling and its implications for cardioprotection and antiarrhythmogenesis

    Article • The Lancet, February 2013, Elsevier

    Professor Andrew Trafford

  73. Diastolic Spontaneous Calcium Release From the Sarcoplasmic Reticulum Increases Beat-to-Beat Variability of Repolarization in Canine Ventricular Myocytes After  -Adrenergic Stimulation

    Article • Circulation Research, November 2012, Wolters Kluwer Health

    Dr Daniel Johnson, Professor Andrew Trafford

  74. Age-related divergent remodeling of the cardiac extracellular matrix in heart failure: Collagen accumulation in the young and loss in the aged

    Article • Journal of Molecular and Cellular Cardiology, July 2012, Elsevier

    Professor Andrew Trafford

  75. Enhanced Sarcoplasmic Reticulum Ca2+ Leak and Increased Na+-Ca2+ Exchanger Function Underlie Delayed Afterdepolarizations in Patients With Chronic Atrial Fibrillation

    Article • Circulation, March 2012, Wolters Kluwer Health

    Professor Andrew Trafford

  76. Localised micro-mechanical stiffening in the ageing aorta

    Article • Mechanisms of Ageing and Development, October 2011, Elsevier

    Brian Derby, Professor Andrew Trafford

  77. Changes of SERCA activity have only modest effects on sarcoplasmic reticulum Ca2+content in rat ventricular myocytes

    Article • The Journal of Physiology, September 2011, Wiley

    Professor Andrew Trafford

  78. Transverse tubules are a common feature in large mammalian atrial myocytes including human

    Article • AJP Heart and Circulatory Physiology, August 2011, American Physiological Society

    Professor Andrew Trafford

  79. The devil is in the details: Methodological reviews—A new JMCC initiative

    Article • Journal of Molecular and Cellular Cardiology, June 2011, Elsevier

    Professor Andrew Trafford

  80. How can we improve our understanding of cardiovascular safety liabilities to develop safer medicines?

    Article • Bone Marrow Transplantation, May 2011, Wiley

    Professor Andrew Trafford

  81. Impaired β-adrenergic responsiveness accentuates dysfunctional excitation-contraction coupling in an ovine model of tachypacing-induced heart failure

    Article • The Journal of Physiology, March 2011, Wiley

    Professor Andrew Trafford

  82. Ca2+ wave probability is determined by the balance between SERCA2-dependent Ca2+ reuptake and threshold SR Ca2+ content

    Article • Cardiovascular Research, January 2011, European Society of Cardiology

    Professor Andrew Trafford

  83. Primum non nocere: When will ryanodine receptor leak find its role in heart failure?

    Article • Journal of Molecular and Cellular Cardiology, January 2011, Elsevier

    Professor Andrew Trafford

  84. In the RyR2R4496C Mouse Model of CPVT,  -Adrenergic Stimulation Induces Ca Waves by Increasing SR Ca Content and Not by Decreasing the Threshold for Ca Waves

    Article • Circulation Research, October 2010, Wolters Kluwer Health

    Professor Andrew Trafford

  85. How does CaMKIIδ phosphorylation of the cardiac ryanodine receptor contribute to inotropy?

    Article • Proceedings of the National Academy of Sciences, July 2010, Proceedings of the National Academy of Sciences

    Professor Andrew Trafford

  86. Tissue section AFM: In situ ultrastructural imaging of native biomolecules

    Article • Matrix Biology, May 2010, Elsevier

    A/Prof Thomas R Cox, Professor Andrew Trafford

  87. Calcium Signaling in Cardiac Muscle

    Article • January 2010, Elsevier

    Professor Andrew Trafford

  88. Reduced SERCA2 abundance decreases the propensity for Ca2+ wave development in ventricular myocytes

    Article • Cardiovascular Research, December 2009, European Society of Cardiology

    Professor Andrew Trafford

  89. Keeping the beat: Life without SERCA — Is it possible?

    Article • Journal of Molecular and Cellular Cardiology, August 2009, Elsevier

    Professor Andrew Trafford

  90. Characterization of an Extensive Transverse Tubular Network in Sheep Atrial Myocytes and its Depletion in Heart Failure

    Article • Circulation Heart Failure, July 2009, Wolters Kluwer Health

    Professor Andrew Trafford

  91. What is the purpose of the large sarcolemmal calcium flux on each heartbeat?

    Article • AJP Heart and Circulatory Physiology, June 2009, American Physiological Society

    Professor Andrew Trafford

  92. The mechanism and significance of the slow changes of ventricular action potential duration following a change of heart rate

    Article • Experimental Physiology, April 2009, Wiley

    Professor Andrew Trafford

  93. Differences in intracellular calcium homeostasis between atrial and ventricular myocytes

    Article • Journal of Molecular and Cellular Cardiology, April 2009, Elsevier

    Professor Andrew Trafford

  94. What role does modulation of the ryanodine receptor play in cardiac inotropy and arrhythmogenesis?

    Article • Journal of Molecular and Cellular Cardiology, April 2009, Elsevier

    Professor Andrew Trafford

  95. Nanoindentation of histological specimens: Mapping the elastic properties of soft tissues

    Article • Journal of Materials Research, March 2009, Cambridge University Press

    Brian Derby, Professor Andrew Trafford

  96. From the Ryanodine Receptor to Cardiac Arrhythmias

    Article • Circulation Journal, January 2009, Japanese Circulation Society

    Professor Andrew Trafford

  97. Extracellular matrix profiles in the progression to heart failure

    Article • Acta Physiologica, September 2008, Wiley

    Professor Andrew Trafford

  98. Regulation of systolic [Ca2+]iand cellular Ca2+flux balance in rat ventricular myocytes by SR Ca2+, L-type Ca2+current and diastolic [Ca2+]i

    Article • The Journal of Physiology, December 2007, Wiley

    Professor Andrew Trafford

  99. Analysis of cellular calcium fluxes in cardiac muscle to understand calcium homeostasis in the heart

    Article • Cell Calcium, October 2007, Elsevier

    Professor Andrew Trafford

  100. The sarcoplasmic reticulum and arrhythmogenic calcium release

    Article • Cardiovascular Research, September 2007, European Society of Cardiology

    Professor Andrew Trafford

  101. Na/Ca Exchange: Regulator of Intracellular Calcium and Source of Arrhythmias in the Heart

    Article • Annals of the New York Academy of Sciences, February 2007, Wiley

    Professor Andrew Trafford

  102. Increasing Ryanodine Receptor Open Probability Alone Does Not Produce Arrhythmogenic Calcium Waves: Threshold Sarcoplasmic Reticulum Calcium Content Is Required

    Article • Circulation Research, January 2007, Wolters Kluwer Health

    Professor Andrew Trafford

  103. Spatial disruption and enhanced degradation of collagen with the transition from compensated ventricular hypertrophy to symptomatic congestive heart failure

    Article • AJP Heart and Circulatory Physiology, October 2006, American Physiological Society

    Professor Andrew Trafford

  104. Life, Sudden Death, and Intracellular Calcium

    Article • Circulation Research, August 2006, Wolters Kluwer Health

    Professor Andrew Trafford

  105. Reducing Ryanodine Receptor Open Probability as a Means to Abolish Spontaneous Ca2+ Release and Increase Ca2+ Transient Amplitude in Adult Ventricular Myocytes

    Article • Circulation Research, May 2006, Wolters Kluwer Health

    Professor Andrew Trafford

  106. A mechanism distinct from the L-type Ca current or Na–Ca exchange contributes to Ca entry in rat ventricular myocytes

    Article • Cell Calcium, May 2006, Elsevier

    Professor Andrew Trafford

  107. The control of sarcoplasmic reticulum Ca content in cardiac muscle

    Article • Cell Calcium, September 2005, Elsevier

    Professor Andrew Trafford

  108. Stability and instability of regulation of intracellular calcium

    Article • Experimental Physiology, December 2004, Wiley

    Professor Andrew Trafford

  109. Photoperiod-dependent modulation of cardiac excitation contraction coupling in the Siberian hamster

    Article • AJP Regulatory Integrative and Comparative Physiology, November 2004, American Physiological Society

    Professor Andrew Trafford

  110. Mechanisms underlying enhanced cardiac excitation contraction coupling observed in the senescent sheep myocardium

    Article • Journal of Molecular and Cellular Cardiology, November 2004, Elsevier

    Professor Andrew Trafford

  111. Enhanced sarcolemmal Ca2+ efflux reduces sarcoplasmic reticulum Ca2+ content and systolic Ca2+ in cardiac hypertrophy

    Article • Cardiovascular Research, June 2004, European Society of Cardiology

    Professor Andrew Trafford

  112. Physiological and pathological modulation of ryanodine receptor function in cardiac muscle

    Article • Cell Calcium, June 2004, Elsevier

    Professor Andrew Trafford

  113. DYNAMICS OF CARDIAC INTRACELLULAR Ca 2+ HANDLING — FROM EXPERIMENTS TO VIRTUAL CELLS

    Article • International Journal of Bifurcation and Chaos, December 2003, World Scientific Pub Co Pte Lt

    Henggui Zhang, Professor Andrew Trafford

  114. Location, location, location: new avenues to determine the function of the cardiac Na+–Ca2+ exchanger?

    Article • Journal of Molecular and Cellular Cardiology, November 2003, Elsevier

    Professor Andrew Trafford

  115. Illuminating Sarcoplasmic Reticulum Calcium

    Article • Circulation Research, July 2003, Wolters Kluwer Health

    Professor Andrew Trafford

  116. No role for a voltage sensitive release mechanism in cardiac muscle

    Article • Journal of Molecular and Cellular Cardiology, February 2003, Elsevier

    Professor Andrew Trafford

  117. Heart Failure and the Ryanodine Receptor: Does Occam's Razor Rule?

    Article • Circulation Research, November 2002, Wolters Kluwer Health

    Professor Andrew Trafford

  118. The Effects of Exogenous Calcium Buffers on the Systolic Calcium Transient in Rat Ventricular Myocytes

    Article • Biophysical Journal, April 2001, Elsevier

    Professor Andrew Trafford

  119. The role of intracellular Ca buffers in determining the shape of the systolic Ca transient in cardiac ventricular myocytes

    Article • Pflügers Archiv - European Journal of Physiology, February 2001, Springer Science + Business Media

    Professor Andrew Trafford

  120. Coordinated Control of Cell Ca 2+ Loading and Triggered Release From the Sarcoplasmic Reticulum Underlies the Rapid Inotropic Response to Increased L-Type Ca 2+ Current

    Article • Circulation Research, February 2001, Wolters Kluwer Health

    Professor Andrew Trafford

  121. Integrative Analysis of Calcium Cycling in Cardiac Muscle

    Article • Circulation Research, December 2000, Wolters Kluwer Health

    Professor Andrew Trafford

  122. The effect of acidosis on systolic Ca2+and sarcoplasmic reticulum calcium content in isolated rat ventricular myocytes

    Article • The Journal of Physiology, December 2000, Wiley

    Professor Andrew Trafford

  123. The effects of low concentrations of caffeine on spontaneous Ca release in isolated rat ventricular myocytes

    Article • Cell Calcium, October 2000, Elsevier

    Professor Andrew Trafford

  124. The Ryanodine Receptor: Cause or Consequence of Diabetic Heart Failure?

    Article • Journal of Molecular and Cellular Cardiology, July 2000, Elsevier

    Professor Andrew Trafford

  125. Can changes of ryanodine receptor expression affect cardiac contractility?

    Article • Cardiovascular Research, March 2000, European Society of Cardiology

    Professor Andrew Trafford

  126. Measurement of calcium entry and exit in quiescent rat ventricular myocytes

    Article • Pflügers Archiv - European Journal of Physiology, January 2000, Springer Science + Business Media

    Professor Andrew Trafford

  127. A novel, rapid and reversible method to measure Ca buffering and time-course of total sarcoplasmic reticulum Ca content in cardiac ventricular myocytes

    Article • Pflügers Archiv - European Journal of Physiology, January 1999, Springer Science + Business Media

    Professor Andrew Trafford

  128. Measurement of Sarcoplasmic Reticulum Ca Content and Sarcolemmal Fluxes during the Transient Stimulation of the Systolic Ca Transient Produced by Caffeine

    Article • Annals of the New York Academy of Sciences, September 1998, Wiley

    Professor Andrew Trafford

  129. 2,3-Butanedione monoxime (BDM) decreases sarcoplasmic reticulum Ca content by stimulating Ca release in isolated rat ventricular myocytes

    Article • Pflügers Archiv - European Journal of Physiology, August 1998, Springer Science + Business Media

    Professor Andrew Trafford

  130. The control of Ca release from the cardiac sarcoplasmic reticulum: regulation versus autoregulation

    Article • Cardiovascular Research, June 1998, European Society of Cardiology

    Professor Andrew Trafford

  131. Ca-activated chloride current and Na-Ca exchange have different timecourses during sarcoplasmic reticulum Ca release in ferret ventricular myocytes

    Article • Pflügers Archiv - European Journal of Physiology, March 1998, Springer Science + Business Media

    Professor Andrew Trafford

  132. Stimulation of Ca-induced Ca release only transiently increases the systolic Ca transient: measurements of Ca fluxes and sarcoplasmic reticulum Ca

    Article • Cardiovascular Research, March 1998, European Society of Cardiology

    Professor Andrew Trafford

  133. Enhanced Ca 2+ Current and Decreased Ca 2+ Efflux Restore Sarcoplasmic Reticulum Ca 2+ Content After Depletion

    Article • Circulation Research, October 1997, Wolters Kluwer Health

    Professor Andrew Trafford

  134. A measurable reduction of s.r. Ca content follows spontaneous Ca release in rat ventricular myocytes

    Article • Pflügers Archiv - European Journal of Physiology, September 1997, Springer Science + Business Media

    Professor Andrew Trafford

  135. Measurement of sarcoplasmic reticulum Ca2+content and sarcolemmal Ca2+fluxes in isolated rat ventricular myocytes during spontaneous Ca2+release

    Article • The Journal of Physiology, May 1997, Wiley

    Professor Andrew Trafford

  136. Variability of Spontaneous Ca 2+ Release Between Different Rat Ventricular Myocytes Is Correlated With Na + -Ca 2+ Exchange and [Na

    Article • Circulation Research, May 1996, Wolters Kluwer Health

    Professor Andrew Trafford

  137. Use of medetomidine and butorphanol for sedation in dogs

    Article • Journal of Small Animal Practice, October 1994, Wiley

    Professor Andrew Trafford

  138. Factors affecting the propagation of locally activated systolic Ca transients in rat ventricular myocytes

    Article • Pflügers Archiv - European Journal of Physiology, October 1993, Springer Science + Business Media

    Professor Andrew Trafford