All Stories

  1. Structure and function of MDM2 and MDM4 in health and disease

    Article • Biochemical Journal, February 2025, Portland Press Ltd.

    William R Critchley, Mr Dhananjay Dasiram Jade

  2. “Affimer” synthetic protein scaffolds block oxidized LDL binding to the LOX-1 scavenger receptor and inhibit ERK1/2 activation

    Article • Journal of Biological Chemistry, November 2023, Elsevier

    Mr Dhananjay Dasiram Jade, William R Critchley

  3. The E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2D2 regulate VEGFR2 dynamics and endothelial function

    Article • Journal of Cell Science, May 2023, The Company of Biologists

    William R Critchley

  4. VEGFR endocytosis: Implications for angiogenesis

    Article • January 2023, Elsevier

    William R Critchley

  5. Identification of FDA-approved drugs against SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) through computational virtual screening

    Article • Structural Chemistry, November 2022, Springer Science + Business Media

    Mr Dhananjay Dasiram Jade, William R Critchley

  6. Monitoring VEGF-Stimulated Calcium Ion Flux in Endothelial Cells

    Article • January 2022, Springer Science + Business Media

    William R Critchley

  7. A multicentre review comparing long term outcomes of endoscopic vein harvesting versus open vein harvesting for coronary artery bypass surgery

    Article • NIHR Open Research, July 2021, National Institute for Health Research

    William R Critchley

  8. Low Incidence of Structural Valve Degeneration With the Trifecta Aortic Valve Bioprosthesis.

    Article • June 2021, Springer Science + Business Media

    William R Critchley

  9. A post-preservation vascular flush removes significant populations of donor leukocytes prior to lung transplantation

    Article • Transplant Immunology, February 2021, Elsevier

    William R Critchley

  10. Financial implications of using extracorporeal membrane oxygenation following heart transplantation

    Article • Interactive Cardiovascular and Thoracic Surgery, December 2020, Oxford University Press (OUP)

    William R Critchley

  11. Non-ischemic Heart Preservation via Hypothermic Cardioplegic Perfusion Induces Immunodepletion of Donor Hearts Resulting in Diminished Graft Infiltration Following Transplantation

    Article • Frontiers in Immunology, July 2020, Frontiers

    William R Critchley, Professor Andrew Trafford

  12. Ex Vivo Lung Perfusion Improves the Inflammatory Signaling Profile of the Porcine Donor Lung Following Transplantation

    Article • Transplantation, June 2020, Wolters Kluwer Health

    William R Critchley

  13. A Randomized Study Comparing the Incidence of Postoperative Pain After Phrenic Nerve Infiltration Vs Nonphrenic Nerve Infiltration During Thoracotomy

    Article • Seminars in Thoracic and Cardiovascular Surgery, January 2019, Elsevier

    Dr Catherine Fullwood, William R Critchley

  14. Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking

    Article • Cells, March 2018, MDPI AG

    William R Critchley

  15. The effect of 1.5 T cardiac magnetic resonance on human circulating leucocytes

    Article • European Heart Journal, November 2017, Oxford University Press (OUP)

    William R Critchley

  16. Ex-vivo flush of the limb allograft reduces inflammatory burden prior to transplantation

    Article • Journal of Plastic Reconstructive & Aesthetic Surgery, November 2017, Elsevier

    William R Critchley

  17. Randomized Study Comparing the Effect of Carbon Dioxide Insufflation on Veins using 2 Types of Endoscopic and Open Vein Harvesting

    Article • Innovations Technology and Techniques in Cardiothoracic and Vascular Surgery, September 2017, SAGE Publications

    William R Critchley

  18. Vein integrity after harvesting for coronary artery bypass grafting

    Article • Circulation, June 2017, Wolters Kluwer Health

    William R Critchley

  19. Characterizing the early inflammatory contribution of the donor kidney following reperfusion

    Article • Nephrology Dialysis Transplantation, February 2017, Oxford University Press (OUP)

    William R Critchley

  20. Ex Vivo Normothermic Perfusion Induces Donor-Derived Leukocyte Mobilization and Removal Prior to Renal Transplantation

    Article • Kidney International Reports, November 2016, Elsevier

    William R Critchley

  21. A comprehensive review on learning curve associated problems in endoscopic vein harvesting and the requirement for a standardised training programme

    Article • Journal of Cardiothoracic Surgery, April 2016, Springer Science + Business Media

    William R Critchley

  22. A randomized study comparing traditional monofilament knotted sutures with barbed knotless sutures for donor leg wound closure in coronary artery bypass surgery

    Article • Interactive Cardiovascular and Thoracic Surgery, November 2015, Oxford University Press (OUP)

    William R Critchley

  23. Reduced graft infiltration with ex vivo lung perfusion

    Article • Arabian archaeology and epigraphy, September 2015, Wiley

    William R Critchley

  24. Does the introduction of a comprehensive structured training programme for endoscopic vein harvesting improve conduit quality? A multicentre pilot study

    Article • Interactive Cardiovascular and Thoracic Surgery, November 2014, Oxford University Press (OUP)

    William R Critchley

  25. Histological and immunohistochemical evaluation of human saphenous vein harvested by endoscopic and open conventional methods

    Article • Interactive Cardiovascular and Thoracic Surgery, October 2014, Oxford University Press (OUP)

    William R Critchley

  26. Specialist initiation and monitoring of beta blockers in patients with chronic heart failure and concomitant obstructive airways disease

    Article • International Journal of Cardiology, September 2013, Elsevier

    William R Critchley

  27. Second Line Options for Hyperlipidemia Management after Cardiac Transplantation

    Article • Cardiovascular Therapeutics, April 2013, Wiley

    William R Critchley

  28. Heart Rate After Cardiac Transplantation—Lessons From the Tortoise and the Shrew

    Article • Transplantation, January 2013, Wolters Kluwer Health

    William R Critchley

  29. Should We Consider Heart Rate Reduction in Cardiac Transplant Recipients?

    Article • Clinical Cardiology, August 2012, Wiley

    William R Critchley

  30. Characterisation of the T cell and dendritic cell repertoire in a murine model of mucopolysaccharidosis I (MPS I)

    Article • Journal of Inherited Metabolic Disease, July 2012, Springer Science + Business Media

    William R Critchley

  31. A randomized study comparing three groups of vein harvesting methods for coronary artery bypass grafting: endoscopic harvest versus standard bridging and open techniques

    Article • Interactive Cardiovascular and Thoracic Surgery, May 2012, Oxford University Press (OUP)

    William R Critchley

  32. Graft rejection - endogenous or allogeneic?

    Article • Immunology, April 2012, Wiley

    William R Critchley

  33. Brain natriuretic peptide induces CD8+ T cell death via a caspase 3 associated pathway — Implications following heart transplantation

    Article • Transplant Immunology, March 2012, Elsevier

    William R Critchley

  34. The Effect of Beta-Blockers on the Adaptive Immune System in Chronic Heart Failure

    Article • Cardiovascular Therapeutics, September 2009, Wiley

    William R Critchley