All Stories

  1. Deciphering of Cytotoxicity in Fungal-Derived Cytochalasans Using a Deep Neural Network Framework Supported by Molecular Docking and Molecular Dynamic Simulations

    Article • Journal of Computational Biophysics and Chemistry, April 2026, World Scientific Pub Co Pte Lt

    Dr Amr El-Demerdash

  2. Crop metabolic engineering towards enhanced resistance to pests and pathogens

    Article • The Crop Journal, February 2026, Tsinghua University Press

    Dr Amr El-Demerdash

  3. Enzymology and Structural Basis of Glycosyltransferases Involved in Saponin C28 Carboxylic Acid O - d -Fucosylation

    Article • JACS Au, November 2025, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  4. Chemical profiling of Lycium shawii via RP-HPLC-QTOF-MS and MS/MS: unveiling its in-vivo wound-healing potential supported by molecular docking investigations

    Article • Fitoterapia, September 2025, Elsevier

    Dr Amr El-Demerdash

  5. Natural Remedies for Hypercholesteremia

    Article • August 2025, Taylor & Francis

    Dr Amr El-Demerdash

  6. Natural Remedies in Disease Management and Treatment

    Article • August 2025, Taylor & Francis

    Dr Amr El-Demerdash

  7. Assessment of Wound Healing Properties of Medicinal Plants: The Case of Berlinia confusa

    Article • Natural Product Communications, January 2025, SAGE Publications

    Dr Amr El-Demerdash

  8. The cytochalasans: potent fungal natural products with application from bench to bedside

    Article • Natural Product Reports, January 2025, Royal Society of Chemistry

    Dr Amr El-Demerdash

  9. Cortistatin and plakinamine steroidal alkaloids from the marine sponges of the genus Corticium: insights into their chemistry, pharmacology, pharmacokinetics and structure activity relationships (SARs)

    Article • RSC Advances, January 2025, Royal Society of Chemistry

    Dr Amr El-Demerdash

  10. Metabolic Profiling via UPLC/MS/MS and In Vitro Cholinesterase, Amylase, Glucosidase, and Tyrosinase Inhibitory Effects of Carica papaya L. Extracts Reveal Promising Nutraceutical Potential

    Article • Food Analytical Methods, October 2024, Springer Science + Business Media

    Dr Amr El-Demerdash

  11. Cephalostatins and ritterazines: Distinctive dimeric marine-derived steroidal pyrazine alkaloids with intriguing anticancer activities

    Article • Bioorganic Chemistry, October 2024, Elsevier

    Dr Amr El-Demerdash

  12. Investigating the Structure-Activity Relationship of Laulimalides Marine Macrolides as Promising Inhibitors for SARS-CoV-2 Main Protease (Mpro)

    Article • Journal of Computational Biophysics and Chemistry, September 2024, World Scientific Pub Co Pte Lt

    Dr Amr El-Demerdash

  13. Unlocking saponin biosynthesis in soapwort

    Article • Nature Chemical Biology, July 2024, Springer Science + Business Media

    Dr Amr El-Demerdash

  14. Employing acetoacetamide as a key synthon for synthesizing novel thiophene derivatives and assessing their potential as antioxidants and antimicrobial agents

    Article • Journal of Heterocyclic Chemistry, May 2024, Wiley

    Dr Amr El-Demerdash

  15. Complete biosynthesis of QS-21 in engineered yeast

    Article • Nature, May 2024, Springer Science + Business Media

    Dr Amr El-Demerdash

  16. Synthesis and molecular docking of some new thiazolidinone and thiadiazole derivatives as anticancer agents

    Article • Chemistry & Biodiversity, March 2024, Wiley

    Dr Amr El-Demerdash

  17. SYNTHESIS OF SOME NOVEL THIOPHENE ANALOGUES AS POTENTIAL ANTICANCER AGENTS

    Article • Chemistry & Biodiversity, March 2024, Wiley

    Dr Amr El-Demerdash

  18. Agro-byproduct valorization of radish and turnip leaves and roots as new sources of antibacterial and antivirulence agents through metabolomics and molecular networking

    Article • Scientia Horticulturae, March 2024, Elsevier

    Dr Amr El-Demerdash

  19. Anthocyanins - dietary natural products with a variety of bioactivities for the promotion of human and animal health

    Article • Animal Science Papers and Reports, March 2024, De Gruyter

    Dr Amr El-Demerdash

  20. Complete biosynthesis of the potent vaccine adjuvant QS-21

    Article • Nature Chemical Biology, January 2024, Springer Science + Business Media

    Dr Amr El-Demerdash

  21. Unveiling the Potential of Marine-Derived Diterpenes from the order Alcyonacea as Promising Anti-obesity Agents

    Article • Current Research in Biotechnology, January 2024, Elsevier

    Dr Amr El-Demerdash

  22. Deciphering the potential of Cymbopogon citratus (DC.) Stapf as an anti-obesity agent: phytochemical profiling, in vivo evaluations and molecular docking studies

    Article • Food & Function, January 2024, Royal Society of Chemistry

    Dr Amr El-Demerdash

  23. Discovery of isoflavone phytoalexins in wheat reveals an alternative route to isoflavonoid biosynthesis

    Article • Nature Communications, November 2023, Springer Science + Business Media

    Dr Amr El-Demerdash

  24. Dietary factors in nonalcoholic fatty liver disease: impacts on human and animal health - a review

    Article • Animal Science Papers and Reports, September 2023, De Gruyter

    Dr Amr El-Demerdash, Dr Javier Echeverría

  25. Investigating the antiviral therapeutic potentialities of marine polycyclic lamellarin pyrrole alkaloids as promising inhibitors for SARS-CoV-2 and Zika main proteases (Mpro)

    Article • Journal of Biomolecular Structure and Dynamics, May 2023, Taylor & Francis

    Dr Amr El-Demerdash

  26. Signal crosstalk of phytomelatonin during salinity stress tolerance in plants

    Article • Plant Growth Regulation, May 2023, Springer Science + Business Media

    Dr Amr El-Demerdash

  27. Investigating the Structure-Activity Relationship of Laulimalides Marine Macrolides as Promising Inhibitors for SARS-CoV-2 Main Protease (Mpro)

    Article • May 2023, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  28. Elucidation of the pathway for biosynthesis of saponin adjuvants from the soapbark tree

    Article • Science, March 2023, American Association for the Advancement of Science

    Dr Amr El-Demerdash

  29. Recent Advances in Discovery, Biosynthesis and Therapeutic Potentialities of Isocoumarins Derived from Fungi: A Comprehensive Update

    Article • February 2023, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  30. The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis

    Article • Phytomedicine, January 2023, Elsevier

    Dr Amr El-Demerdash, Professor George Perry, Prof. Antoni Sureda, Dr Smith B. Babiaka, Humboldt Fellow, Prof. Tomasz M. Karpiński, Dr Hemanth kumar Boyina , Hitesh Chopra, Jesus Simal-Gandara, Dr Javier Echeverría, Mr SHRAVAN PASWAN

  31. Recent advances in the discovery, biosynthesis, and therapeutic potential of isocoumarins derived from fungi: a comprehensive update

    Article • RSC Advances, January 2023, Royal Society of Chemistry

    Dr Amr El-Demerdash

  32. Investigating the hepatoprotective potentiality of marine-derived steroids as promising inhibitors of liver fibrosis

    Article • RSC Advances, January 2023, Royal Society of Chemistry

    Dr Amr El-Demerdash

  33. Pederins, mycalamides, onnamides and theopederins: Distinctive polyketide families with intriguing therapeutic potentialities

    Article • Current Research in Biotechnology, January 2023, Elsevier

    Dr Amr El-Demerdash

  34. Investigating the Antiviral Therapeutic Potentialities of Marine Polycyclic Lamellarin Pyrrole Alkaloids as Promising Inhibitors for SARS-CoV-2 and Zika Main Proteases (Mpro)

    Article • October 2022, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  35. Chemical Diversity, Biological Activities and Biosynthesis of Fungal Naphthoquinones and Their Derivatives: A Comprehensive Update

    Article • Journal of Molecular Structure, July 2022, Elsevier

    Dr Amr El-Demerdash

  36. Investigating the structure-activity relationship of marine polycyclic batzelladine alkaloids as promising inhibitors for SARS-CoV-2 main protease (Mpro)

    Article • Computers in Biology and Medicine, June 2022, Elsevier

    Dr Amr El-Demerdash

  37. Chemical Diversity and Biological Activities of Anthraquinones Derived from Marine Fungi: A Comprehensive Update

    Article • March 2022, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  38. Investigating the Structure-Activity Relationship of Marine Polycyclic Batzelladine Alkaloids as Promising Inhibitors for SARS-CoV-2 Main Protease (Mpro)

    Article • March 2022, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  39. Chemical diversity, medicinal potentialities, biosynthesis, and pharmacokinetics of anthraquinones and their congeners derived from marine fungi: a comprehensive update

    Article • RSC Advances, January 2022, Royal Society of Chemistry

    Dr Amr El-Demerdash

  40. Marine Brominated Tyrosine Alkaloids as Promising Inhibitors of SARS-CoV-2

    Article • Molecules, October 2021, MDPI AG

    Dr Amr El-Demerdash

  41. Punica granatum L var nana: A Hepatoprotective and Curative Agent Against CCl4 Induced Hepatotoxicity in Rats

    Article • Egyptian Journal of Chemistry, October 2021, Egypts Presidential Specialized Council for Education and Scientific Research

    Dr Amr El-Demerdash

  42. A unique view of SARS-CoV-2 through the lens of ORF8 protein

    Article • Computers in Biology and Medicine, June 2021, Elsevier

    Dr Amr El-Demerdash, Ángel Serrano Aroca, Dr Amos Lal

  43. Comprehensive Virtual Screening of the Antiviral Potentialities of Marine Polycyclic Guanidine Alkaloids against SARS-CoV-2 (COVID-19)

    Article • Biomolecules, March 2021, MDPI AG

    Dr Amr El-Demerdash

  44. Bioactive Bromotyrosine Derivatives from the Pacific Marine Sponge Suberea clavata (Pulitzer-Finali, 1982)

    Article • Marine Drugs, March 2021, MDPI AG

    Dr Amr El-Demerdash

  45. Cytotoxic constituents from the wheat plant pathogen Parastagonospora nodorum SN15

    Article • Natural Product Research, February 2021, Taylor & Francis

    Dr Amr El-Demerdash, Pr Alexandre E Escargueil

  46. Investigating the structure–activity relationship of marine natural polyketides as promising SARS-CoV-2 main protease inhibitors

    Article • RSC Advances, January 2021, Royal Society of Chemistry

    Dr Amr El-Demerdash

  47. Comprehensive Virtual Screening of the Antiviral Potentialities of Marine Polycyclic Guanidine Alkaloids against SARS-CoV-2 (Covid-19)

    Article • December 2020, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  48. Comprehensive Virtual Screening of the Antiviral Potentialities of Marine Polycyclic Guanidine Alkaloids against SARS-CoV-2 (Covid-19)

    Article • December 2020, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  49. A new triterpene saponin from Fagonia schimperi

    Article • Journal of Applied Biology & Biotechnology, December 2020, Journal of Applied Pharmaceutical Science

    Dr Amr El-Demerdash

  50. Insights about clinically approved and Preclinically investigated marine natural products

    Article • Current Research in Biotechnology, November 2020, Elsevier

    Dr Amr El-Demerdash, Mosad Ghareeb

  51. Crambescidin Acid from the French Polynesian Monanchora n. sp. Marine Sponge

    Article • Chemistry of Natural Compounds, November 2020, Springer Science + Business Media

    Dr Amr El-Demerdash

  52. A Review: Synthesis and Medicinal Importance of Coumarins and their Analogues (Part II)

    Article • Current Bioactive Compounds, October 2020, Bentham Science Publishers

    Dr Amr El-Demerdash, Professor Moustafa A. Gouda, Dr. Belal H.M Hussein, Mohamed Ibrahim , wafaa hamama

  53. Short-Cut Bio-Inspired Synthesis of Tricyclic Guanidinic Motifs of Crambescidins and Batzelladines Marine Alkaloids

    Article • European Journal of Organic Chemistry, June 2020, Wiley

    Dr Amr El-Demerdash

  54. Chemical Diversity and Biological Activities of Meroterpenoids from Marine Derived-Fungi: A Comprehensive Update

    Article • Marine Drugs, June 2020, MDPI AG

    Dr Amr El-Demerdash

  55. Synthesis and biological evaluation of some heterocyclic scaffolds based on the multifunctional N ‐(4‐acetylphenyl)‐2‐chloroacetamide

    Article • Journal of Heterocyclic Chemistry, May 2020, Wiley

    Dr Amr El-Demerdash

  56. Utilization of 5‐Chloro‐2‐(cyanoacetamido)pyridines in the Synthesis of Biologically Active Heterocyclic Hybrids

    Article • ChemistrySelect, February 2020, Wiley

    Dr Amr El-Demerdash

  57. Highly oxygenated isoprenylated cyclohexanoids from the fungus Parastagonospora nodorum SN15

    Article • Phytochemistry, October 2019, Elsevier

    Dr Amr El-Demerdash

  58. Chemical Diversity and Biological Activities of Marine Sponges of the Genus Suberea: A Systematic Review

    Article • Marine Drugs, February 2019, MDPI AG

    Dr Amr El-Demerdash

  59. Chemical Diversity and Biological Activities of Phaeosphaeria Fungi Genus: A Systematic Review

    Article • Journal of Fungi, December 2018, MDPI AG

    Dr Amr El-Demerdash

  60. Fatty Acids Pattern from the French Polynesian Monanchora n. sp. Marine Sponge

    Article • Chemistry of Natural Compounds, November 2018, Springer Science + Business Media

    Dr Amr El-Demerdash

  61. Phytol: A review of biomedical activities

    Article • Food and Chemical Toxicology, November 2018, Elsevier

    Dr Amr El-Demerdash, Prof. Maciej Banach, Dr. Utpal Kumar Karmakar, Manik Shill, Mohammad S. Mubarak

  62. Chemistry and Biological Activities of the Marine Sponges of the Genera Mycale (Arenochalina), Biemna and Clathria

    Article • Marine Drugs, June 2018, MDPI AG

    Dr Atanas G. Atanasov, Dr Amr El-Demerdash

  63. Bioactive Bromotyrosine-Derived Alkaloids from the Polynesian Sponge Suberea ianthelliformis

    Article • Marine Drugs, April 2018, MDPI AG

    Dr Amr El-Demerdash

  64. Batzella, Crambe and Monanchora: Highly Prolific Marine Sponge Genera Yielding Compounds with Potential Applications for Cancer and Other Therapeutic Areas

    Article • Nutrients, January 2018, MDPI AG

    Dr Amr El-Demerdash

  65. Molecular Responses of Cancers by Natural Products: Modifications of Autophagy Revealed by Literature Analysis

    Article • Critical Reviews™ in Oncogenesis, January 2018, Begell House

    Dr Amr El-Demerdash

  66. Unguiculins A-C: cytotoxic bis-guanidine alkaloids from the French Polynesian sponge, Monanchora n. sp

    Article • Natural Product Research, October 2017, Taylor & Francis

    Dr Amr El-Demerdash

  67. Cytotoxic Guanidine Alkaloids from a French Polynesian Monanchora n. sp. Sponge

    Article • Journal of Natural Products, July 2016, American Chemical Society (ACS)

    Dr Amr El-Demerdash

  68. Gingerdione from the rhizomes of Curcuma longa

    Article • Chemistry of Natural Compounds, September 2012, Springer Science + Business Media

    Dr Amr El-Demerdash

  69. Isolation of Bioactive Marine Natural Products and Bioinspired Synthesis of Fused Guanidinic Tricyclic Analogues

    Article • Agence Bibliographique de l'Enseignement Supérieur

    Dr Amr El-Demerdash