All Stories

  1. Cetyl All-Trans-Retinoate as a Lipidic ATRA Prodrug with Enhanced Anticancer and Chemosensitizing Activity
  2. Phosphoramidate Derivatives of Betulin, New Molecules with Promising Biological Activity: Synthesis and Characterization
  3. Evaluation of the Lipophilicity of 3,28-Disubstituted Betulin Derivatives with Promising Biological Properties
  4. Probing the Hydrophobic Part of Analogues of the Incadronate-Evidence of Their Interaction with Immunological System of Sheep
  5. Studies on the Complexation of Platinum(II) by Some 4-Nitroisothiazoles and the Cytotoxic Activity of the Resulting Complexes
  6. Phytochemical Profile, Extraction and Characterization of Bioactive Compounds from Industrial Hemp (Cannabis sativa L.) Felina 32 Variety
  7. Betulin-Hippuric Acid Conjugates: Chemistry, Antiproliferative Activity and Mechanism of Action
  8. Extraction of Cannabinoids and Terpenes from Hemp Flowers and Leaves (Cannabis sativa L., Futura 75): Chemical Profiling and Evaluation of Anticancer Properties
  9. New Difunctional Derivatives of Betulin: Preparation, Characterization and Antiproliferative Potential
  10. 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside Reduces Cyclophosphamide Effects and Induces Endothelial Inflammation in Murine Breast Cancer Model
  11. Vibrational and DFT Studies and Anticancer Activity of Novel Pd(II) and Pt(II) Complexes with Chloro Derivatives of 7-Azaindole-3-Carbaldehyde
  12. Synthesis, Structure, and In Vitro Biological Evaluation of Semi-Synthetic Derivatives of Betulin
  13. Synergistic Proliferation Effects of Xanthohumol and Niflumic Acid on Merkel and Glioblastoma Cancer Cells: Role of Cell Membrane Interactions
  14. 4-Hydroxybenzoic Acid-Based Hydrazide–Hydrazones as Potent Growth Inhibition Agents of Laccase-Producing Phytopathogenic Fungi That Are Useful in the Protection of Oilseed Crops
  15. Age-Dependent Effect of Calcitriol on Mouse Regulatory T and B Lymphocytes
  16. An Organofluorine Isoselenocyanate Analogue of Sulforaphane Affects Antimetabolite 5-Fluorouracil’s Anticancer Activity: A Perspective for New Combinatory Therapy in Triple-Negative Breast Cancer
  17. Prenylated Flavonoids with Selective Toxicity against Human Cancers
  18. Studies on the Complexation of Platinum(II) by Some 4-Nitroisoxazoles and Testing the Cytotoxic Activity of the Resulting Complexes
  19. Diclofenac Loaded Biodegradable Nanoparticles as Antitumoral and Antiangiogenic Therapy
  20. Cholinesterases Inhibition, Anticancer and Antioxidant Activity of Novel Benzoxazole and Naphthoxazole Analogs
  21. Novel Strategies against Cancer: Dexibuprofen-Loaded Nanostructured Lipid Carriers
  22. Microfluidic-Assisted Human Cancer Cells Culturing Platform for Space Biology Applications
  23. Vitamin D, Th17 Lymphocytes, and Breast Cancer
  24. Discovery of New 3,3-Diethylazetidine-2,4-dione Based Thiazoles as Nanomolar Human Neutrophil Elastase Inhibitors with Broad-Spectrum Antiproliferative Activity
  25. Synthesis, crystal structure and spectroscopic characterization of new anionic iridium(III) complexes and their interaction with biological targets
  26. 4-Pyridone-3-carboxamide-1-β-D-ribonucleoside (4PYR)—A Novel Oncometabolite Modulating Cancer-Endothelial Interactions in Breast Cancer Metastasis
  27. Relationship between Telomere Length, TERT Genetic Variability and TERT, TP53, SP1, MYC Gene Co-Expression in the Clinicopathological Profile of Breast Cancer
  28. Micro-RNAs in Response to Active Forms of Vitamin D3 in Human Leukemia and Lymphoma Cells
  29. The Impact of Exosomes/Microvesicles Derived from Myeloid Dendritic Cells Cultured in the Presence of Calcitriol and Tacalcitol on Acute B-Cell Precursor Cell Lines with MLL Fusion Gene
  30. Polymorphism of VDR Gene and the Sensitivity of Human Leukemia and Lymphoma Cells to Active Forms of Vitamin D
  31. BSG (CD147) Serum Level and Genetic Variants Are Associated with Overall Survival in Acute Myeloid Leukaemia
  32. Aromatic Bis[aminomethylidenebis(phosphonic)] Acids Prevent Ovariectomy-Induced Bone Loss and Suppress Osteoclastogenesis in Mice
  33. Synthesis and antiproliferative screening of novel doubly modified colchicines containing urea, thiourea and guanidine moieties
  34. Improved HDAC Inhibition, Stronger Cytotoxic Effect and Higher Selectivity against Leukemias and Lymphomas of Novel, Tricyclic Vorinostat Analogues
  35. Synthesis and Structure of Novel Copper(II) Complexes with N,O- or N,N-Donors as Radical Scavengers and a Functional Model of the Active Sites in Metalloenzymes
  36. Novel Vorinostat Analogues with Improved HDAC Inhibition, Stronger Cytotoxic Effect and Higher Selectivity Against Leukemias and Lymphomas
  37. Effect of the dichloro-substitution on antiproliferative activity of phthalimide-thiazole derivatives. Rational design, synthesis, elastase, caspase 3/7, and EGFR tyrosine kinase activity and molecular modeling study
  38. Synthesis and Antiproliferative Activity of Triazoles Based on 2-Azabicycloalkanes
  39. An insight into the anticancer potential of carbamates and thiocarbamates of 10-demethoxy-10-methylaminocolchicine
  40. Vitamin D Compounds PRI-2191 and PRI-2205 Enhance Anastrozole Activity in Human Breast Cancer Models
  41. Differential Response of Lung Cancer Cells, with Various Driver Mutations, to Plant Polyphenol Resveratrol and Vitamin D Active Metabolite PRI-2191
  42. Synthesis of novel phytol-derived γ-butyrolactones and evaluation of their biological activity
  43. Synthesis, anticancer activity and molecular docking studies of N-deacetylthiocolchicine and 4-iodo-N-deacetylthiocolchicine derivatives
  44. Synthesis and Anticancer Evaluation of Novel Derivatives of Isoxazolo[4,5-e][1,2,4]triazepine Derivatives and Potential Inhibitors of Protein Kinase C
  45. Photoinduced Skeletal Rearrangement of N-Substituted Colchicine Derivatives
  46. N‐Methylated Analogs of hIAPP Fragments 18–22, 23–27, 33–37 Inhibit Aggregation of the Amyloidogenic Core of the Hormone
  47. Synthesis of Platinum(II) Complexes with Some 1-Methylnitropyrazoles and In Vitro Research on Their Cytotoxic Activity
  48. Calcitriol in the Presence of Conditioned Media from Metastatic Breast Cancer Cells Enhances Ex Vivo Polarization of M2 Alternative Murine Bone Marrow-Derived Macrophages
  49. Biaryl Sulfonamides Based on the 2-Azabicycloalkane Skeleton—Synthesis and Antiproliferative Activity
  50. Vitamin D Metabolite Profile in Cholecalciferol- or Calcitriol-Supplemented Healthy and Mammary Gland Tumor-Bearing Mice
  51. Heterogeneity of telomerase reverse transcriptase mutation and expression, telomerase activity and telomere length across human cancer cell lines cultured in vitro
  52. Protein Disulphide Isomerase A1 Is Involved in the Regulation of Breast Cancer Cell Adhesion and Transmigration via Lung Microvascular Endothelial Cells
  53. Differential Impact of Calcitriol and Its Analogs on Tumor Stroma in Young and Aged Ovariectomized Mice Bearing 4T1 Mammary Gland Cancer
  54. New Human Islet Amyloid Polypeptide Fragments Susceptible to Aggregation
  55. Ruthenium(II) and Iridium(III) Complexes as Tested Materials for New Anticancer Agents
  56. New Series of Double-Modified Colchicine Derivatives: Synthesis, Cytotoxic Effect and Molecular Docking
  57. Synthesis and Anticancer Activity of Dimeric Polyether Ionophores
  58. Octahydroquinoxalin-2(1H)-One-Based Aminophosphonic Acids and Their Derivatives—Biological Activity towards Cancer Cells
  59. The halogenation of natural flavonoids, baicalein and chrysin, enhances their affinity to human protein kinase CK2
  60. Synthesis, Antiproliferative Activity and Molecular Docking Studies of Novel Doubly Modified Colchicine Amides and Sulfonamides as Anticancer Agents
  61. Synthesis, biological evaluation and molecular docking studies of new amides of 4-chlorothiocolchicine as anticancer agents
  62. Three-Component Reaction of Diamines with Triethyl Orthoformate and Diethyl Phosphite and Anti-Proliferative and Antiosteoporotic Activities of the Products
  63. Retinol-Binding Protein 4 Accelerates Metastatic Spread and Increases Impairment of Blood Flow in Mouse Mammary Gland Tumors
  64. Synthesis and Antiproliferative Screening Of Novel Analogs of Regioselectively Demethylated Colchicine and Thiocolchicine
  65. Synthesis, CYP24A1-Dependent Metabolism and Antiproliferative Potential against Colorectal Cancer Cells of 1,25-Dihydroxyvitamin D2 Derivatives Modified at the Side Chain and the A-Ring
  66. Application of TLC to Evaluate the Lipophilicity of Newly Synthesized Betulin Derivatives
  67. Divergent Effect of Tacalcitol (PRI-2191) on Th17 Cells in 4T1 Tumor Bearing Young and Old Ovariectomized Mice
  68. Assessment of the in vitro controlled release for some polymeric nanocomposites loaded with different drugs
  69. The N’-Substituted Derivatives of 5-Chloro-3-Methylisothiazole-4-Carboxylic Acid Hydrazide with Antiproliferative Activity
  70. The influence of a single and double biotinylation of xanthohumol on its anticancer activity
  71. The influence of acupuncture TENS currents on the proliferation of cancer cells tested in vitro
  72. Synthesis, biological evaluation and molecular docking studies of new amides of 4-bromothiocolchicine as anticancer agents
  73. Design, synthesis and antiproliferative activity against human cancer cell lines of novel benzo-, benzofuro-, azolo- and thieno-1,3-thiazinone resorcinol hybrids
  74. IL-33 – positive or negative role in cancer progression?
  75. Insulin enhancement of the antitumor activity of chemotherapeutic agents in colorectal cancer is linked with downregulating PIK3CA and GRB2
  76. De‑O‑acylated lipooligosaccharide of E.�coli B reduces the number of metastatic foci via downregulation of myeloid cell activity
  77. EGFR-targeted immunoliposomes as a selective delivery system of simvastatin, with potential use in treatment of triple-negative breast cancers
  78. Differential response of lung cancer cell lines to vitamin D derivatives depending on EGFR, KRAS, p53 mutation status and VDR polymorphism
  79. The 5-hydrazino-3-methylisothiazole-4-carboxylic acid, its new 5-substituted derivatives and their antiproliferative activity
  80. Synthesis, antiproliferative activity, and molecular docking studies of 4‐chlorothiocolchicine analogues
  81. Biological effects of aromatic bis[aminomethylidenebis(phosphonic)] acids in osteoclast precursors in vitro
  82. 3,4-dimethoxybenzyl isothiocyanate enhances doxorubicin efficacy in LoVoDX doxorubicin-resistant colon cancer and attenuates its toxicity in vivo
  83. Discovery of tropinone-thiazole derivatives as potent caspase 3/7 activators, and noncompetitive tyrosinase inhibitors with high antiproliferative activity: Rational design, one-pot tricomponent synthesis, and lipophilicity determination
  84. Influence of amide versus ester linkages on the anticancer properties of the new flavone–biotin conjugates
  85. Antiproliferative activity of ester derivatives of monensin A at the C‐1 and C‐26 positions
  86. Structure–Antioxidant–Antiproliferative Activity Relationships of Natural C7 and C7–C8 Hydroxylated Flavones and Flavanones
  87. Structural Modifications of Nature-Inspired Indoloquinolines: A Mini Review of Their Potential Antiproliferative Activity
  88. New phosphate derivatives of betulin as anticancer agents: Synthesis, crystal structure, and molecular docking study
  89. Tacalcitol increases the sensitivity of colorectal cancer cells to 5-fluorouracil by downregulating the thymidylate synthase
  90. Similarities and differences in d6 low-spin ruthenium, rhodium and iridium half-sandwich complexes: synthesis, structure, cytotoxicity and interaction with biological targets
  91. Platinum(II) and copper(II) complexes of 7-azaindole-3-carboxaldehyde: crystal structures, IR and Raman spectra, DFT calculations and in vitro antiproliferative activity of the platinum(II) complex
  92. Biological Activity and In Silico Study of 3-Modified Derivatives of Betulin and Betulinic Aldehyde
  93. Triazene salts: Design, synthesis, ctDNA interaction, lipophilicity determination, DFT calculation, and antiproliferative activity against human cancer cell lines
  94. Calcitriol Analogues Decrease Lung Metastasis but Impair Bone Metabolism in Aged Ovariectomized Mice Bearing 4T1 Mammary Gland Tumours
  95. Temporal inhibition of mouse mammary gland cancer metastasis by CORM-A1 and DETA/NO combination therapy
  96. Spectroscopic, structural and anticancer activity studies of (−)-cytisine halogenated N-benzyl derivatives
  97. Synthesis and electrochemical, spectral, and biological evaluation of novel 9,10-anthraquinone derivatives containing piperidine unit as potent antiproliferative agents
  98. Synthesis, crystal structure, 1H, 13C and 15N NMR studies, and biological evaluation of a new amidrazone-derived Au(III) complex
  99. Steroid hormone calcitriol and its analog tacalcitol inhibit miR-125b expression in a human breast cancer MCF-7 cell line
  100. DESIGN, SYNTHESIS AND ANALYSIS OF ANTICANCER ACTIVITY OF NEW SAR-BASED S16020 DERIVATIVES
  101. Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes
  102. Synthesis and Biological Evaluation of Novel Triple-Modified Colchicine Derivatives as Potent Tubulin-Targeting Anticancer Agents
  103. Highly Cancer Selective Antiproliferative Activity of Natural Prenylated Flavonoids
  104. Antiproliferative Activity and Molecular Docking of Novel Double-Modified Colchicine Derivatives
  105. Picoplatin-based complexes with the bioactive orotate and 5-fluoroorotate ligands: Synthesis, DFT calculations, structure, spectroscopic characterization and in vitro cytotoxicity
  106. Synthesis, physicochemical and theoretical studies on new rhodium and ruthenium dimers. Relationship between structure and cytotoxic activity
  107. Plant lyophilisate carrying S-HBsAg as an oral booster vaccine against HBV
  108. New mono- and dinuclear complexes of 7-azaindole-3-carboxaldehyde with palladium(II): crystal structure, IR and Raman spectra, DFT calculations and in vitro antiproliferative activity
  109. Combination Therapy with DETA/NO and Clopidogrel Inhibits Metastasis in Murine Mammary Gland Cancer Models via Improved Vasoprotection
  110. Triazole Biheterocycles from Cinchona Alkaloids: Coordination and Antiproliferative Properties
  111. Synthesis, Characterization, and In Vitro Cancer Cell Growth Inhibition Evaluation of Novel Phosphatidylcholines with Anisic and Veratric Acids
  112. Nitric oxide deficiency and endothelial–mesenchymal transition of pulmonary endothelium in the progression of 4T1 metastatic breast cancer in mice
  113. Biological activity of doubly modified salinomycin analogs – Evaluation in vitro and ex vivo
  114. Phosphorus-containing isothiocyanate-derived mercapturic acids as a useful alternative for parental isothiocyanates in experimental oncology
  115. Calcitriol and Its Analogs Establish the Immunosuppressive Microenvironment That Drives Metastasis in 4T1 Mouse Mammary Gland Cancer
  116. Biotinylated xanthohumol: synthesis and <em>in vitro</em> biological evaluation for anticancer therapy
  117. The Antiproliferative Activity and Molecular Docking studies of some sulfonamides against cancer cell lines compared to normal cells
  118. Synthesis and biological activity of novel benzoazoles, benzoazines and other analogs functionalized by 2,4-dihydroxyphenyl moiety
  119. Alterations in NO- and PGI2- dependent function in aorta in the orthotopic murine model of metastatic 4T1 breast cancer: relationship with pulmonary endothelial dysfunction and systemic inflammation
  120. Discovering simple phenylboronic acid and benzoxaborole derivatives for experimental oncology – phase cycle-specific inducers of apoptosis in A2780 ovarian cancer cells
  121. One-pot synthesis and antiproliferative activity of novel double-modified derivatives of the polyether ionophore monensin A
  122. Efficient glycosylation of natural Danshensu and its enantiomer by sugar and 2-deoxy sugar donors
  123. Cyclo(Pro-DOPA), a third identified bioactive metabolite produced by Streptomyces sp. 8812
  124. Cell Density-Dependent Cytological Stage Profile and Its Application for a Screen of Cytostatic Agents Active Toward Leukemic Stem Cells
  125. Synthesis and Antiproliferative Activity of Minor Hops Prenylflavonoids and New Insights on Prenyl Group Cyclization
  126. Dual antiplatelet therapy with clopidogrel and aspirin increases mortality in 4T1 metastatic breast cancer-bearing mice by inducing vascular mimicry in primary tumour
  127. Synthesis, structure, DNA binding and anticancer activity of mixed ligand ruthenium(II) complex
  128. Synthesis, molecular docking, ctDNA interaction, DFT calculation and evaluation of antiproliferative and anti-Toxoplasma gondii activities of 2,4-diaminotriazine-thiazole derivatives
  129. Novel (S )-1,3,4,12a-tetrahydropyrazino[2,1- c ][1,4]benzodiazepine-6,12(2 H ,11 H )-dione derivatives: Selective inhibition of MV-4-11 biphenotypic B myelomonocytic leukemia cells’ growth is accompanied by reactive oxygen species overproduction and ap...
  130. In search of new anticancer drug – Dimethylsulfoxide ruthenium(III) complex with bulky triazolopyrimidine derivative and preliminary studies towards understanding the mode of action
  131. Synthesis and biological evaluation of acyl derivatives of hydroxyflavones as potent antiproliferative agents against drug resistance cell lines
  132. Uptake and bioreactivity of charged chitosan-coated superparamagnetic nanoparticles as promising contrast agents for magnetic resonance imaging
  133. Synthesis and biological evaluation of phosphatidylcholines with cinnamic and 3-methoxycinnamic acids with potent antiproliferative activity
  134. Vitamin�D derivatives potentiate the anticancer and anti-angiogenic activity of tyrosine kinase inhibitors in combination with cytostatic drugs in an A549 non-small cell lung cancer model
  135. Design, Synthesis, and Evaluation of ω-(Isothiocyanato)alkylphosphinates and Phosphine Oxides as Antiproliferative Agents
  136. Clopidogrel in a combined therapy with anticancer drugs—effect on tumor growth, metastasis, and treatment toxicity: Studies in animal models
  137. Synthesis and In Vitro Antiproliferative Activity of 11-Substituted Neocryptolepines with a Branched ω-Aminoalkylamino Chain
  138. Unfavorable effect of calcitriol and its low-calcemic analogs on metastasis of 4T1 mouse mammary gland cancer
  139. Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7
  140. An efficient synthesis of indolo[2,3-b]quinoline guanidine derivatives with their in vitro and in vivo study
  141. Aminophosphinates against Helicobacter pylori ureolysis—Biochemical and whole-cell inhibition characteristics
  142. Methotrexate and epirubicin conjugates as potential antitumor drugs
  143. Rational design of dicarboxylato platinum(II) complexes with purine-mimetic ligands as novel anticancer agents
  144. Bivalent polyether ionophores: Synthesis and biological evaluation of C2-symmetric salinomycin dimers
  145. Synthesis and evaluation of cytotoxic activity of conjugated linoleic acid derivatives (esters, alcohols, and their acetates) toward cancer cell lines
  146. Novel phosphonate analogs of sulforaphane: Synthesis, in vitro and in vivo anticancer activity
  147. Magnesium cinnamate complex, [Mg(cinn)2(H2O)2]n; structural, spectroscopic, thermal, biological and pharmacokinetical characteristics
  148. New chiral Mannich adducts of di-tert-butylphenols and a bicyclic imine – Synthesis and antiproliferative activity
  149. The effects of 1,4-dimethylpyridine in metastatic prostate cancer in mice
  150. Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling
  151. Isoprenoid-phospholipid conjugates as potential therapeutic agents: Synthesis, characterization and antiproliferative studies
  152. Reaction of 3-Amino-1,2,4-Triazole with Diethyl Phosphite and Triethyl Orthoformate: Acid-Base Properties and Antiosteoporotic Activities of the Products
  153. Syntheses and antiproliferative activities of novel phosphatidylcholines containing dehydroepiandrosterone moieties
  154. Differences in Antiproliferative Activity Between Salinomycin-AZT Conjugates Obtained via ‘Click’ and Esterification Reactions
  155. Robust oil-core nanocapsules with hyaluronate-based shells as promising nanovehicles for lipophilic compounds
  156. Synthesis and biological evaluation of 4'-O-acetyl-isoxanthohumol and its analogues as antioxidant and antiproliferative agents
  157. Synthesis, crystal structure and cytotoxic activity of ruthenium(II) piano-stool complex with N,N-chelating ligand
  158. Heparin-binding copolymer reverses effects of unfractionated heparin, enoxaparin, and fondaparinux in rats and mice
  159. Molecular docking studies, biological and toxicity evaluation of dihydroisoquinoline derivatives as potential anticancer agents
  160. Antiangiogenic cancer treatment: The great discovery and greater complexity (Review)
  161. New acetylenic derivatives of betulin and betulone, synthesis and cytotoxic activity
  162. Synthesis, structure and antiproliferative activity of chiral polyamines based on a 2-azanorbornane skeleton
  163. Thiazole-based nitrogen mustards: Design, synthesis, spectroscopic studies, DFT calculation, molecular docking, and antiproliferative activity against selected human cancer cell lines
  164. A novel canine B-cell leukaemia cell line. Establishment, characterisation and sensitivity to chemotherapeutics
  165. Synthesis and antiproliferative activity of some N′-substituted 2,4-dihydroxybenzothiohydrazides
  166. 1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis
  167. Rapid biochemical profiling of endothelial dysfunction in diabetes, hypertension and cancer metastasis by hierarchical cluster analysis of Raman spectra
  168. Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents
  169. Dehalogenation Activity of Selected Fungi Towardδ-Iodo-γ-Lactone Derived fromtrans,trans-Farnesol
  170. The Toxicokinetic Profile of Dex40-GTMAC3—a Novel Polysaccharide Candidate for Reversal of Unfractionated Heparin
  171. 3D Raman imaging of systemic endothelial dysfunction in the murine model of metastatic breast cancer
  172. Synthesis, antiproliferative activity and molecular docking of Colchicine derivatives
  173. Oral Administration of Polymyxin B Modulates the Activity of Lipooligosaccharide E. coli B against Lung Metastases in Murine Tumor Models
  174. Synthesis, structure and cytotoxic activity of acetylenic derivatives of betulonic and betulinic acids
  175. Indolo[2,3-b]quinoline derivatives as novel promising antitumor agents
  176. Synthesis and biological activity of diisothiocyanate-derived mercapturic acids
  177. Synthesis of 4-(4-methylidene-4H-3,1-benzothiazin-2-yl)benzene1,3-diols and their antiproliferative activity against human cancer cell lines
  178. Synthesis and Investigation of the Antitumor Properties of Novel, Bicyclic Furopyrimidine, Pyrrolopyrimidine and Pyrimidopyridazine Nucleoside Analogues
  179. Slow-release nanopolymeric biodegradable composites holding doxorubicin and evaluation its antiproliferative potency on cancer
  180. N-Arylaminomethylenebisphosphonates Bearing Fluorine Atoms: Synthesis and Antiosteoporotic Activity
  181. Vitamin D Analogs Potentiate the Antitumor Effect of Imatinib Mesylate in a Human A549 Lung Tumor Model
  182. The synthesis of indolo[2,3-b]quinoline derivatives with a guanidine group: Highly selective cytotoxic agents
  183. Bicyclic cytarabine analogues: synthesis and investigation of antitumor properties of novel, 6-aryl- and 6-alkyl-3H-pyrrolo[2,3-d]pyrimidin-2(7H)-one arabinosides
  184. Antiproliferative Activity and in Vivo Toxicity of Double-Point Modified Analogs of 1,25-Dihydroxyergocalciferol
  185. Anti-proliferative activity of Monensin and its tertiary amide derivatives
  186. Synthesis and antiproliferative activity of new bioconjugates of Salinomycin with amino acid esters
  187. Acetate platinum(II) compound with 5,7-ditertbutyl-1,2,4-triazolo[1,5-a]pyrimidine that overcomes cisplatin resistance: structural characterization,in vitrocytotoxicity, and kinetic studies
  188. Endothelium and cancer metastasis: Perspectives for antimetastatic therapy
  189. Synthesis and Antiproliferative Activity of Silybin Conjugates with Salinomycin and Monensin
  190. Synthesis and biological activity of salinomycin conjugates with floxuridine
  191. Antiproliferative Activity of Polyether Antibiotic -CinchonaAlkaloid Conjugates ObtainedviaClick Chemistry
  192. Synthesis, antiproliferative and antibacterial evaluation of C-ring modified colchicine analogues
  193. Phosphatidylcholine with cis-9,trans-11 and trans-10,cis-12 Conjugated Linoleic Acid Isomers: Synthesis and Cytotoxic Studies
  194. The Disulfide Analogues of Isophosphoramide Mustard for Anticancer Therapy
  195. Cytotoxic malonate platinum(II) complexes with 1,2,4-triazolo[1,5- a ]pyrimidine derivatives: Structural characterization and mechanism of the suppression of tumor cell growth
  196. Synthesis, Anticancer and Antibacterial Activity of Salinomycin N-Benzyl Amides
  197. Design, Synthesis, and Biological Evaluation of Artemisinin-Indoloquinoline Hybrids as Potent Antiproliferative Agents
  198. An efficient process to directly convert 1-hydroxymethyl-3,5-dimethylpyrazole to Cd(ii) complexes via C–N bond creation: cytotoxicity and factors controlling the structures
  199. Synthesis and In Vitro Antiproliferative Activity of Thiazole-Based Nitrogen Mustards: The Hydrogen Bonding Interaction between Model Systems and Nucleobases
  200. Bacteriophages displaying anticancer peptides in combined antibacterial and anticancer treatment
  201. Vitamin D analogs combined with 5-fluorouracil in human HT-29 colon cancer treatment
  202. Synthesis and antiproliferative activity in vitro of new 2-aminobenzimidazole derivatives. Reaction of 2-arylideneaminobenzimidazole with selected nitriles containing active methylene group
  203. Hydroxyethyl starch as an effective methotrexate carrier in anticancer therapy
  204. Searching for new derivatives of neocryptolepine: Synthesis, antiproliferative, antimicrobial and antifungal activities
  205. Synthesis and in vitro cytotoxic effect of 6-amino-substituted 11H- and 11Me-indolo[3,2-c]quinolines
  206. Synthesis, antiproliferative and antibacterial activity of new amides of salinomycin
  207. Synthesis, cytotoxicity and antibacterial activity of new esters of polyether antibiotic – salinomycin
  208. Efficient Human Breast Cancer Xenograft Regression after a Single Treatment with a Novel Liposomal Formulation of Epirubicin Prepared Using the EDTA Ion Gradient Method
  209. Structural Factors Affecting Cytotoxic Activity of (E)-1-(Benzo[d ][1,3]oxathiol-6-yl)-3-phenylprop-2-en-1-one Derivatives
  210. Freeze-Drying of Plant Tissue Containing HBV Surface Antigen for the Oral Vaccine against Hepatitis B
  211. Cancer – Could it be Cured? A Spontaneous Regression of Cancer, Cancer Energy Metabolism, Hyperglycemia-Hypoglycemia, Metformin, Warburg and Crabtree Effects and a New Perspective in Cancer Treatment
  212. Crystal structure, infrared and EPR spectra and anticancer activity in vitro of the novel manganese(II) complexes of indolecarboxylic acids
  213. Synthetic Access to Poly-Substituted 11H-Pyrido[3,2-a]carbazoles, a DNA-Intercalating Ellipticine Related Structure, and Their Antiproliferative Activity
  214. Design, synthesis, and in vitro cancer cell growth inhibition evaluation and antimalarial testing of trioxanes installed in cyclic 2-enoate substructures
  215. Synthesis and Biological Activity of Diastereomeric and Geometric Analogs of Calcipotriol, PRI-2202 and PRI-2205, Against Human HL-60 Leukemia and MCF-7 Breast Cancer Cells
  216. Synthesis, characterization and antiproliferative activity of β-aryl-δ-iodo-γ-lactones
  217. One-pot synthesis and cytotoxicity studies of new Mannich base derivatives of polyether antibiotic—Lasalocid acid
  218. Novel Genistein Derivatives Induce Cell Death and Cell Cycle Arrest Through Different Mechanisms
  219. Corrigendum to “The antileukemic activity of modified fibrinogen–methotrexate conjugate” [Biochim. Biophys. Acta 1830 (2013) 2526–2530]
  220. Synthesis of new pyrimidine derivatives and their antiproliferative activity against selected human cancer cell lines
  221. Vitamin D analogs enhance the anticancer activity of 5-fluorouracil in an in vivomouse colon cancer model
  222. Synthesis, Structure and Cytotoxic Activity of New Acetylenic Derivatives of Betulin
  223. Antioxidant and antiproliferative activity of glycosides obtained by biotransformation of xanthohumol
  224. Fungal metabolites of xanthohumol with potent antiproliferative activity on human cancer cell lines in vitro
  225. Synthesis and Cytotoxic Activity of New Betulin and Betulinic Acid Esters with Conjugated Linoleic Acid (CLA)
  226. The antileukemic activity of modified fibrinogen–methotrexate conjugate
  227. Structure–activity relationship disturbed by a solvolytic process: Study on the [Cu(II)-4-nitropyridine N-oxide derivative] system
  228. In vitro antiproliferative activity of 11-aminoalkylamino-substituted 5H-indolo[2,3-b]quinolines; improving activity of neocryptolepines by installation of ester substituent
  229. Synthesis of Phosphatidylcholine with Conjugated Linoleic Acid and Studies on Its Cytotoxic Activity
  230. X-ray crystallographic, FT-IR and NMR studies as well as anticancer and antibacterial activity of the salt formed between ionophore antibiotic Lasalocid acid and amines
  231. Antiproliferative activity of salinomycin and its derivatives
  232. Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted chromeno[2,3-b]indoles
  233. Phenolic profile, antioxidant and antiproliferative activity of black and red currants (Ribes spp.) from organic and conventional cultivation
  234. New derivatives of 11-methyl-6-[2-(dimethylamino)ethyl]-6H-indolo[2,3-b]quinoline as cytotoxic DNA topoisomerase II inhibitors
  235. Structure-cytotoxicity relationship for different types of mononuclear platinum(II) complexes with 5,7-ditertbutyl-1,2,4-triazolo[1,5-a]pyrimidine
  236. Convenient syntheses of novel 1-isothiocyano-alkylphosphonate diphenyl ester derivatives with potential biological activity
  237. siRNA-mediated silencing of integrin β3 expression inhibits the metastatic potential of B16 melanoma cells
  238. Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted 5H- and 6H-indolo[2,3-b]quinolines; structure–activity relationships of neocryptolepines and 6-methyl congeners
  239. Synthesis and Biological Evaluation of New Amino Acid and Dipeptide Derivatives of Neocryptolepine as Anticancer Agents
  240. One-Pot Synthesis of New (1,3-Thiazolo[5,4-b]pyridin-2-yl)benzenediols and Their Antiproliferative Activities against Human Cancer Cell Lines
  241. The in-vitro antiproliferative effect of PRI-2191 and imatinib applied in combined treatment with cisplatin, idarubicin, or docetaxel on human leukemia cells
  242. Synthesis and biological activity of novel 4- and 6-(1-alkyl/aryl-1H-benzimidazol-2-yl)benzene-1,3-diols
  243. Synthesis and cytotoxicity studies of bifunctional hybrids of nitrogen mustards with potential enzymes inhibitors based on melamine framework
  244. Synthesis and antiproliferative activity of novel α- and β-dialkoxyphosphoryl isothiocyanates
  245. Systematic coordination chemistry and cytotoxicity of copper(II) complexes with methyl substituted 4-nitropyridine N-oxides
  246. HSAB principle and nickel(II) ion reactivity towards 1-methyhydantoin
  247. Microbial transformation of (+)-nootkatone and the antiproliferative activity of its metabolites
  248. Synthesis and characterization of chloro-bis(quinoline-2-carboxylato-κ2N,O)gallium(III)
  249. Simple phosphonic inhibitors of human neutrophil elastase
  250. Synthesis of a Natural γ-Butyrolactone from Nerylacetone by Acremonium roseum and Fusarium oxysporum Cultures
  251. Silver(I) complexes with hydantoins and allantoin☆Synthesis, crystal and molecular structure, cytotoxicity and pharmacokinetics
  252. Synthetic conjugates of genistein affecting proliferation and mitosis of cancer cells
  253. Anticancer activity of the Uncaria tomentosa (Willd.) DC. preparations with different oxindole alkaloid composition
  254. Synthesis and in vitro antiproliferative activity of novel (4-chloro- and 4-acyloxy-2-butynyl)thioquinolines
  255. Antitumor properties of (5E,7E) analogs of vitamin D3
  256. Mononuclear copper(II) nitrato complexes with methyl-substituted 4-nitropyridine N-oxide. Physicochemical and cytotoxic characteristics
  257. Organotin Compound Derived from 3-Hydroxy-2-formylpyridine Semicarbazone: Synthesis, Crystal Structure, and Antiproliferative Activity
  258. The effects of staphylococcal bacteriophage lysates on cancer cells in vitro
  259. Atypical calcium coordination number: Physicochemical study, cytotoxicity, DFT calculations and in silico pharmacokinetic characteristics of calcium caffeates
  260. Synthesis and biological properties of oxazolinodaunorubicin—a new derivative of daunorubicin with a modified daunosamine moiety
  261. Synthesis, X-ray structure and antiproliferative activity of 3-benzylthio-4-propargylselenoquinoline
  262. The effect of bacteriophages T4 and HAP1 on in vitro melanoma migration
  263. The influence of 1,25-dihydroxyvitamin D3 and 1,24-dihydroxyvitamin D3 on αvβ3 integrin expression in cancer cell lines
  264. Synthesis and antiproliferative activity in vitro of novel (2-butynyl)thioquinolines
  265. Synthesis and Anticancer Activity of New 1-Substituted-6H-pyrido[4,3-b]carbazole Derivatives
  266. Toxicity and antitumor activity of the vitamin D analogs PRI-1906 and PRI-1907 in combined treatment with cyclophosphamide in a mouse mammary cancer model
  267. Investigating the antiproliferative activity of quinoline-5,8-diones and styrylquinolinecarboxylic acids on tumor cell lines
  268. The Effect of Combined Treatment on Head and Neck Human Cancer Cell Lines With Novel Analogs of Calcitriol and Cytostatics
  269. Antitumor Activity of Mannan–Methotrexate Conjugate In Vitro and In Vivo
  270. Antitumor properties of diastereomeric and geometric analogs of vitamin D3
  271. Hoc protein regulates the biological effects of T4 phage in mammals
  272. Investigation of lipophilicity of anticancer-active thioquinoline derivatives
  273. Synthesis and Antiproliferative Activity in vitro of New Tricyclic 2-Thioxo-1 H ,3 H -imidazo[4,5-b]pyridine Derivatives
  274. Synthesis of 5,6-Dimethyl-9-methoxy-1-phenyl-6H-pyrido[4,3-b]carbazole Derivatives and their Cytotoxic Activity
  275. Activity of Bacteriophages in Murine Tumor Models Depends on the Route of Phage Administration
  276. Synthesis, spectroscopical characterization and the biological activity in vitro of new platinum(II) complexes with imidazo[1,5-a]-1,3,5-triazine derivatives and dimethylsulfoxide
  277. Magnesium deficiency inhibits primary tumor growth but favors metastasis in mice
  278. Toxicity and antineoplastic effect of (24R)-1,24-dihydroxyvitamin D3 (PRI-2191)
  279. New analogues of laminin active fragment YIGSR: synthesis and biological activityin vitro andin vivo
  280. Synthesis and antiproliferative activity in vitro of 2-aminobenzimidazole derivatives
  281. Multinuclear NMR spectroscopy and antitumor activity of novel platinum(II) complexes with 5,7-disubstituted-1,2,4-triazolo[1,5- a ]pyrimidines
  282. Synthesis and Antiproliferative Activity in vitro of New 2-Thioxo-1H, 3H-imidazo[4,5-b]pyridine Derivatives
  283. Synthesis and Cytostatic Activity of 4‐Substituted Derivatives of Isoxazolyltriazenes.
  284. Structure, Properties and Cytostatic Activity of Triorganotin (Aminoaryl)carboxylates
  285. Synthesis and antiproliferative activity of side-chain unsaturated and homologated analogs of 1,25-dihydroxyvitamin D2
  286. Rhodium(III) complexes with polypyridyls and pyrazole and their antitumor activity
  287. Synthesis and antitumour activity of stereoisomers of 4-hydroperoxy derivatives of ifosfamide and its bromo analogue
  288. Synthesis and Antiproliferative Activity in Vitro of New Derivatives of 3-Aminopyrazolo[3,4-b]pyridine Part 1. Reaction of 3-Aminopyrazolo[3,4-b]pyridine with 1,3-, 1,4-Diketones and α,β-Unsaturated Ketones
  289. Tetraacetatodirhodium(II) complexes with tris(methoxyphenyl)phosphines, their reactivity, structure, and antitumor activity
  290. Synthesis and Antiproliferative Activityin Vitro of Novel 1,5-Benzodiazepines. Part II
  291. Synthesis, Characterization and Antiproliferative Activity of the Co(II), Ni(II), Cu(II), Pd(II) and Pt(II) Complexes of 2-(4-Thiazolyl)Benzimidazole (Thiabendazole)
  292. Antiproliferative activity in vitro of new malatoplatinum(II) complexes
  293. Biological Activity In Vitro of Side-Chain Modified Analogues of Calcitriol
  294. Cytotoxic and antitumor effect of fibrinogen-methotrexate conjugate
  295. Metastatic potential and saccharide antigens expression of human colon cancer cells xenotransplanted into athymic nude mice