All Stories

  1. Cholinesterases Inhibition, Anticancer and Antioxidant Activity of Novel Benzoxazole and Naphthoxazole Analogs
  2. Synthesis, crystal structure and spectroscopic characterization of new anionic iridium(III) complexes and their interaction with biological targets
  3. Ruthenium(II) and Iridium(III) Complexes as Tested Materials for New Anticancer Agents
  4. IL-33 – positive or negative role in cancer progression?
  5. Antiproliferative Activity and Molecular Docking of Novel Double-Modified Colchicine Derivatives
  6. Triazole Biheterocycles from Cinchona Alkaloids: Coordination and Antiproliferative Properties
  7. Synthesis, Characterization, and In Vitro Cancer Cell Growth Inhibition Evaluation of Novel Phosphatidylcholines with Anisic and Veratric Acids
  8. Calcitriol and Its Analogs Establish the Immunosuppressive Microenvironment That Drives Metastasis in 4T1 Mouse Mammary Gland Cancer
  9. Alterations in NO- and PGI2- dependent function in aorta in the orthotopic murine model of metastatic 4T1 breast cancer: relationship with pulmonary endothelial dysfunction and systemic inflammation
  10. Discovering simple phenylboronic acid and benzoxaborole derivatives for experimental oncology – phase cycle-specific inducers of apoptosis in A2780 ovarian cancer cells
  11. One-pot synthesis and antiproliferative activity of novel double-modified derivatives of the polyether ionophore monensin A
  12. Efficient glycosylation of natural Danshensu and its enantiomer by sugar and 2-deoxy sugar donors
  13. Cyclo(Pro-DOPA), a third identified bioactive metabolite produced by Streptomyces sp. 8812
  14. Cell Density-Dependent Cytological Stage Profile and Its Application for a Screen of Cytostatic Agents Active Toward Leukemic Stem Cells
  15. Synthesis and Antiproliferative Activity of Minor Hops Prenylflavonoids and New Insights on Prenyl Group Cyclization
  16. Synthesis, molecular docking, ctDNA interaction, DFT calculation and evaluation of antiproliferative and anti-Toxoplasma gondii activities of 2,4-diaminotriazine-thiazole derivatives
  17. Synthesis and biological evaluation of acyl derivatives of hydroxyflavones as potent antiproliferative agents against drug resistance cell lines
  18. Uptake and bioreactivity of charged chitosan-coated superparamagnetic nanoparticles as promising contrast agents for magnetic resonance imaging
  19. Clopidogrel in a combined therapy with anticancer drugs—effect on tumor growth, metastasis, and treatment toxicity: Studies in animal models
  20. Synthesis and In Vitro Antiproliferative Activity of 11-Substituted Neocryptolepines with a Branched ω-Aminoalkylamino Chain
  21. Unfavorable effect of calcitriol and its low-calcemic analogs on metastasis of 4T1 mouse mammary gland cancer
  22. Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7
  23. An efficient synthesis of indolo[2,3-b]quinoline guanidine derivatives with their in vitro and in vivo study
  24. Aminophosphinates against Helicobacter pylori ureolysis—Biochemical and whole-cell inhibition characteristics
  25. Potent covalent inhibitors of bacterial urease identified by activity-reactivity profiling
  26. Reaction of 3-Amino-1,2,4-Triazole with Diethyl Phosphite and Triethyl Orthoformate: Acid-Base Properties and Antiosteoporotic Activities of the Products
  27. Syntheses and antiproliferative activities of novel phosphatidylcholines containing dehydroepiandrosterone moieties
  28. Differences in Antiproliferative Activity Between Salinomycin-AZT Conjugates Obtained via ‘Click’ and Esterification Reactions
  29. Synthesis and biological evaluation of 4'-O-acetyl-isoxanthohumol and its analogues as antioxidant and antiproliferative agents
  30. Heparin-binding copolymer reverses effects of unfractionated heparin, enoxaparin, and fondaparinux in rats and mice
  31. Molecular docking studies, biological and toxicity evaluation of dihydroisoquinoline derivatives as potential anticancer agents
  32. Antiangiogenic cancer treatment: The great discovery and greater complexity (Review)
  33. A novel canine B-cell leukaemia cell line. Establishment, characterisation and sensitivity to chemotherapeutics
  34. Synthesis and antiproliferative activity of some N′-substituted 2,4-dihydroxybenzothiohydrazides
  35. 1-methylnicotinamide and its structural analog 1,4-dimethylpyridine for the prevention of cancer metastasis
  36. Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents
  37. Dehalogenation Activity of Selected Fungi Towardδ-Iodo-γ-Lactone Derived fromtrans,trans-Farnesol
  38. 3D Raman imaging of systemic endothelial dysfunction in the murine model of metastatic breast cancer
  39. Synthesis, antiproliferative activity and molecular docking of Colchicine derivatives
  40. Oral Administration of Polymyxin B Modulates the Activity of Lipooligosaccharide E. coli B against Lung Metastases in Murine Tumor Models
  41. Synthesis and biological activity of diisothiocyanate-derived mercapturic acids
  42. Vitamin D Analogs Potentiate the Antitumor Effect of Imatinib Mesylate in a Human A549 Lung Tumor Model
  43. Antiproliferative Activity and in Vivo Toxicity of Double-Point Modified Analogs of 1,25-Dihydroxyergocalciferol
  44. Synthesis and antiproliferative activity of new bioconjugates of Salinomycin with amino acid esters
  45. Endothelium and cancer metastasis: Perspectives for antimetastatic therapy
  46. Synthesis and Antiproliferative Activity of Silybin Conjugates with Salinomycin and Monensin
  47. Synthesis and biological activity of salinomycin conjugates with floxuridine
  48. Antiproliferative Activity of Polyether Antibiotic -CinchonaAlkaloid Conjugates ObtainedviaClick Chemistry
  49. Synthesis, antiproliferative and antibacterial evaluation of C-ring modified colchicine analogues
  50. The Disulfide Analogues of Isophosphoramide Mustard for Anticancer Therapy
  51. Cytotoxic malonate platinum(II) complexes with 1,2,4-triazolo[1,5- a ]pyrimidine derivatives: Structural characterization and mechanism of the suppression of tumor cell growth
  52. Synthesis, Anticancer and Antibacterial Activity of Salinomycin N-Benzyl Amides
  53. Design, Synthesis, and Biological Evaluation of Artemisinin-Indoloquinoline Hybrids as Potent Antiproliferative Agents
  54. Synthesis and In Vitro Antiproliferative Activity of Thiazole-Based Nitrogen Mustards: The Hydrogen Bonding Interaction between Model Systems and Nucleobases
  55. Bacteriophages displaying anticancer peptides in combined antibacterial and anticancer treatment
  56. Vitamin D analogs combined with 5-fluorouracil in human HT-29 colon cancer treatment
  57. Hydroxyethyl starch as an effective methotrexate carrier in anticancer therapy
  58. Searching for new derivatives of neocryptolepine: Synthesis, antiproliferative, antimicrobial and antifungal activities
  59. Synthesis, antiproliferative and antibacterial activity of new amides of salinomycin
  60. Synthesis, cytotoxicity and antibacterial activity of new esters of polyether antibiotic – salinomycin
  61. Efficient Human Breast Cancer Xenograft Regression after a Single Treatment with a Novel Liposomal Formulation of Epirubicin Prepared Using the EDTA Ion Gradient Method
  62. Structural Factors Affecting Cytotoxic Activity of (E)-1-(Benzo[d ][1,3]oxathiol-6-yl)-3-phenylprop-2-en-1-one Derivatives
  63. Freeze-Drying of Plant Tissue Containing HBV Surface Antigen for the Oral Vaccine against Hepatitis B
  64. Design, synthesis, and in vitro cancer cell growth inhibition evaluation and antimalarial testing of trioxanes installed in cyclic 2-enoate substructures
  65. Synthesis and Biological Activity of Diastereomeric and Geometric Analogs of Calcipotriol, PRI-2202 and PRI-2205, Against Human HL-60 Leukemia and MCF-7 Breast Cancer Cells
  66. One-pot synthesis and cytotoxicity studies of new Mannich base derivatives of polyether antibiotic—Lasalocid acid
  67. Novel Genistein Derivatives Induce Cell Death and Cell Cycle Arrest Through Different Mechanisms
  68. Vitamin D analogs enhance the anticancer activity of 5-fluorouracil in an in vivomouse colon cancer model
  69. Synthesis, Structure and Cytotoxic Activity of New Acetylenic Derivatives of Betulin
  70. Antioxidant and antiproliferative activity of glycosides obtained by biotransformation of xanthohumol
  71. Fungal metabolites of xanthohumol with potent antiproliferative activity on human cancer cell lines in vitro
  72. The antileukemic activity of modified fibrinogen–methotrexate conjugate
  73. Antiproliferative activity of salinomycin and its derivatives
  74. Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted chromeno[2,3-b]indoles
  75. New derivatives of 11-methyl-6-[2-(dimethylamino)ethyl]-6H-indolo[2,3-b]quinoline as cytotoxic DNA topoisomerase II inhibitors
  76. Structure-cytotoxicity relationship for different types of mononuclear platinum(II) complexes with 5,7-ditertbutyl-1,2,4-triazolo[1,5-a]pyrimidine
  77. Synthesis and in vitro antiproliferative activity of new 11-aminoalkylamino-substituted 5H- and 6H-indolo[2,3-b]quinolines; structure–activity relationships of neocryptolepines and 6-methyl congeners
  78. One-Pot Synthesis of New (1,3-Thiazolo[5,4-b]pyridin-2-yl)benzenediols and Their Antiproliferative Activities against Human Cancer Cell Lines
  79. The in-vitro antiproliferative effect of PRI-2191 and imatinib applied in combined treatment with cisplatin, idarubicin, or docetaxel on human leukemia cells
  80. Synthesis and antiproliferative activity of novel α- and β-dialkoxyphosphoryl isothiocyanates
  81. Systematic coordination chemistry and cytotoxicity of copper(II) complexes with methyl substituted 4-nitropyridine N-oxides
  82. Microbial transformation of (+)-nootkatone and the antiproliferative activity of its metabolites
  83. Simple phosphonic inhibitors of human neutrophil elastase
  84. Silver(I) complexes with hydantoins and allantoin☆Synthesis, crystal and molecular structure, cytotoxicity and pharmacokinetics
  85. Synthetic conjugates of genistein affecting proliferation and mitosis of cancer cells
  86. Synthesis and in vitro antiproliferative activity of novel (4-chloro- and 4-acyloxy-2-butynyl)thioquinolines
  87. Mononuclear copper(II) nitrato complexes with methyl-substituted 4-nitropyridine N-oxide. Physicochemical and cytotoxic characteristics
  88. Organotin Compound Derived from 3-Hydroxy-2-formylpyridine Semicarbazone: Synthesis, Crystal Structure, and Antiproliferative Activity
  89. The effects of staphylococcal bacteriophage lysates on cancer cells in vitro
  90. Atypical calcium coordination number: Physicochemical study, cytotoxicity, DFT calculations and in silico pharmacokinetic characteristics of calcium caffeates
  91. Synthesis and biological properties of oxazolinodaunorubicin—a new derivative of daunorubicin with a modified daunosamine moiety
  92. Synthesis and antiproliferative activity in vitro of novel (2-butynyl)thioquinolines
  93. Synthesis and Anticancer Activity of New 1-Substituted-6H-pyrido[4,3-b]carbazole Derivatives
  94. Toxicity and antitumor activity of the vitamin D analogs PRI-1906 and PRI-1907 in combined treatment with cyclophosphamide in a mouse mammary cancer model
  95. Investigating the antiproliferative activity of quinoline-5,8-diones and styrylquinolinecarboxylic acids on tumor cell lines
  96. The Effect of Combined Treatment on Head and Neck Human Cancer Cell Lines With Novel Analogs of Calcitriol and Cytostatics
  97. Antitumor Activity of Mannan–Methotrexate Conjugate In Vitro and In Vivo
  98. Antitumor properties of diastereomeric and geometric analogs of vitamin D3
  99. Hoc protein regulates the biological effects of T4 phage in mammals
  100. Investigation of lipophilicity of anticancer-active thioquinoline derivatives
  101. Synthesis of 5,6-Dimethyl-9-methoxy-1-phenyl-6H-pyrido[4,3-b]carbazole Derivatives and their Cytotoxic Activity
  102. Activity of Bacteriophages in Murine Tumor Models Depends on the Route of Phage Administration
  103. Magnesium deficiency inhibits primary tumor growth but favors metastasis in mice
  104. Toxicity and antineoplastic effect of (24R)-1,24-dihydroxyvitamin D3 (PRI-2191)
  105. New analogues of laminin active fragment YIGSR: synthesis and biological activityin vitro andin vivo
  106. Synthesis and antiproliferative activity in vitro of 2-aminobenzimidazole derivatives
  107. Multinuclear NMR spectroscopy and antitumor activity of novel platinum(II) complexes with 5,7-disubstituted-1,2,4-triazolo[1,5- a ]pyrimidines
  108. Synthesis and antiproliferative activity of side-chain unsaturated and homologated analogs of 1,25-dihydroxyvitamin D2
  109. Synthesis and antitumour activity of stereoisomers of 4-hydroperoxy derivatives of ifosfamide and its bromo analogue
  110. Synthesis and Antiproliferative Activity in Vitro of New Derivatives of 3-Aminopyrazolo[3,4-b]pyridine Part 1. Reaction of 3-Aminopyrazolo[3,4-b]pyridine with 1,3-, 1,4-Diketones and α,β-Unsaturated Ketones
  111. Synthesis and Antiproliferative Activityin Vitro of Novel 1,5-Benzodiazepines. Part II
  112. Synthesis, Characterization and Antiproliferative Activity of the Co(II), Ni(II), Cu(II), Pd(II) and Pt(II) Complexes of 2-(4-Thiazolyl)Benzimidazole (Thiabendazole)
  113. Antiproliferative activity in vitro of new malatoplatinum(II) complexes
  114. Biological Activity In Vitro of Side-Chain Modified Analogues of Calcitriol
  115. Cytotoxic and antitumor effect of fibrinogen-methotrexate conjugate
  116. Metastatic potential and saccharide antigens expression of human colon cancer cells xenotransplanted into athymic nude mice