What is it about?

Particulary gait disturbances and balance remain postoperative issues in the long-term follow up of Parkinsonian patients with bilateral deep brain stimulation (DBS). A new stimulation mode, the short pulse stimulation, revealed an increased therapeutic window and a reduction of stimulation-induced side effects. In our study, we investigated the effect of short pulse DBS on gait, balance and motor symptoms using the GAITRite system and established clinical scores.

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Why is it important?

Our findings show that short pulse DBS and conventional DBS equally improve gait disturbances and motor symptoms in Parkinsonian patients, however short pulse DBS was not superficial over conventional DBS. Still, our data suggest that short pulse DBS might be beneficial in specified cohorts of patients with parkinson's disease.

Perspectives

Short pulse DBS seems to be beneficial for part of the Parkinsonian patients. Therefore, future studies with focus on revealing factors predicting responsiveness to short pulse DBS would be highly interesting.

Aline Seger

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This page is a summary of: Short Pulse and Conventional Deep Brain Stimulation Equally Improve the Parkinsonian Gait Disorder, Journal of Parkinson s Disease, August 2021, IOS Press, DOI: 10.3233/jpd-202492.
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