What is it about?
Ethanol has dual effects against cells. In high concentrations both classic inhibition of growth and metabolism occur, however, this is alongside effects against cell replication. The resulting deactivation (switching-off) of replicative functions allows a cell to continue to grow (enlarge) but not replicate. Such cells can produce elongated cells and appear to switch-on metabolic pathways such as antibiotic production.
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Why is it important?
The specific effects of ethanol and other agents against cell replication has gained greater attention in recent years.
Perspectives
Part of a longer series of the biological effects of ethanol, see http://www.hcaf.biz/2010/Publications_Full.pdf
Dr Rodney P Jones
Healthcare Analysis & Forecasting
Read the Original
This page is a summary of: Roles for Replicative Deactivation in Yeast-Ethanol Fermentations, Critical Reviews in Biotechnology, January 1990, Taylor & Francis,
DOI: 10.3109/07388559009038208.
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