What is it about?
The use one pot reactions in the presence of unconventional solvents like ionic liquids have become a new research direction that has emerged as an important facet of green chemistry. The present work deals constructively with the one pot synthesis of 4-aryl-5-ethoxycarbonyl-3,4-dihydro-6- methylpyrimidin-2(1H)-ones using L-valine sulfate 1:1 [H-Val][HSO4], a cheap, non-corrosive, and eco-friendly ionic liquid as a dual solvent-catalyst
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Why is it important?
This kind of procedures is important as it respects several principles of gren chemistry such as : atom economy, energy and time. the absence of COV.
Perspectives
Our objective is to enlighten the public about the importance of protection and conservation of our environment and about the needs to restrain human activities that lead to indiscriminate release of pollutants into the environment. Thus, the present article describes the synthesis of important compounds with biological activities with the respect of several principles of green chemistry via the use of multicomponent reactions in the presence of non volatil solvent such as ionic liquids.
Professor taoues BOUMOUD
CHEMISTRY DEPARTEMENT CONSTANTINE
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This page is a summary of: Quaternary Ammonium Ionic Liquid as a Dual Solvent-Catalyst in Biginelli Reaction, Letters in Organic Chemistry, October 2016, Bentham Science Publishers,
DOI: 10.2174/1570178613666160824122906.
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