What is it about?
The use one pot reactions in the presence of unconventional solvents like ionic liquids have become a new research direction that has emerged as an important facet of green chemistry. The present work deals constructively with the one pot synthesis of 4-aryl-5-ethoxycarbonyl-3,4-dihydro-6- methylpyrimidin-2(1H)-ones using L-valine sulfate 1:1 [H-Val][HSO4], a cheap, non-corrosive, and eco-friendly ionic liquid as a dual solvent-catalyst
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Why is it important?
This kind of procedures is important as it respects several principles of gren chemistry such as : atom economy, energy and time. the absence of COV.
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This page is a summary of: Quaternary Ammonium Ionic Liquid as a Dual Solvent-Catalyst in Biginelli Reaction, Letters in Organic Chemistry, October 2016, Bentham Science Publishers, DOI: 10.2174/1570178613666160824122906.
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