What is it about?

This review summarizes recent developments in the field of VB1 biocatalysis, allowing the construction of various biologically active heterocyclic scaffolds.

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Why is it important?

Thiamine (VB1) has been proved to be a powerful biocatalyst for various organic transformations. VB1 offers several unique advantages, such as economical, non-toxic, stable and water soluble. Excellent outcomes have been achieved in synthetic applications using VB1 as a catalyst.

Perspectives

Apart from the demonstrated abilities in organic synthesis, applications in other fields are also attractive, for example, in the fields of fluorescent sensors, nanocomposite flms, and nutrient-sensing nanodrug.

yuewei zhang
Jilin Institute of Chemical Technology

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This page is a summary of: Recent Advances of Thiamine in Organic Synthesis, Advanced Synthesis & Catalysis, May 2022, Wiley, DOI: 10.1002/adsc.202200098.
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