What is it about?
The efficient multicomponent synthesis of 3,4-dihydropyrimidin-2(1H)-ones promoted by a heterogeneous Cu/silica xerogel composite is presented herein. This composite was synthesized by the sol-gel methodology employing CuCl2 as the metal source. The catalyst can be easily recovered and reused in subsequent reactions.
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Why is it important?
Metal/Silica Nanocomposites are a recoverable heterogeneous catalyst able to promote several types of reactions catalyzed br Lewis acids such as Cu. After promote the reaction, it can be separated by a simole filtration, dried and reused several times.
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This page is a summary of: Multicomponent Synthesis of 3,4-Dihydropyrimidin-2-(1H)-Ones with a Cu/Silica Xerogel Composite Catalyst, Letters in Organic Chemistry, January 2007, Bentham Science Publishers, DOI: 10.2174/157017807780037496.
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