What is it about?

Peptidic and non-peptidic αvβ6 integrin-binding molecules have been used in the clinic for detection and treatment of tumors expressing αvβ6 integrin, because this protein is expressed in malignant epithelial cells but it is not expressed in healthy adult tissue except during wound healing and inflammation. This review focuses on the landscape of αvβ6 integrin-binding molecules and their use in cancer treatment and detection, and discusses recent designs for tumor detection, treatment, and immunotherapy.

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Why is it important?

This paper gives insights into the basic function of the αvβ6 integrin and some therapeutic approaches made by other researchers around the world.


Writing this article was a great pleasure, we hope you find this article thought-provoking.

Valentina Guevara
Universidad Nacional de Colombia

Read the Original

This page is a summary of: The Role of αvβ6 Integrin Binding Molecules in the Diagnosis and Treatment of Cancer, Current Organic Chemistry, December 2020, Bentham Science Publishers, DOI: 10.2174/1385272824999200528124936.
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