What is it about?

A chemosensor (TPC) based on thymol was afforded by the reaction of thymol and piperidine in methanol. The structure elucidation of TPC was carried out with UV-Vis, 1H-NMR, 13C-NMR, and FT-IR analysis. The chemosensing properties of the synthesized probe were determined with UVvisible spectroscopy, and further, it was exploited for the determination of the concentration of Cu2+ and Pb2+ ions in spiked tap water samples. The toxicity studies of the chemosensing probe were conducted against the plant growth-promoting rhizobacteria (PGPR), i.e., Rhizobium sp., Pseudomonas sp., and Azospirillum sp.

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Why is it important?

Thymol is a naturally occurring monoterpenoid phenol, and its derivatives may emerge as eco-friendly materials for the development of chemosensing probes. We aimed to prepare a non-toxic chemosensing probe based on thymol moiety for the detection of metal ions.

Perspectives

Thymol is a naturally occurring monoterpenoid phenol that has good coordination sites and has been derivatized to compounds such as Mannich bases, esters, imine derivatives etc. These naturally occurring non-toxic compounds and their derivatives may emerge as eco-friendly materials for the development of chemosensing probes. By realizing the importance of biocompatible phenol thymol in the field of sensors, it was anticipated that chemosensors based on thymol moiety might emerge as nontoxic probes for the detection of metal ions. Therefore, in this work, we have prepared the Mannich base of thymol, which was found to be effective for the optical recognition of Cu2+ and Pb2+ ions.

Jyoti Gaba
Punjab Agricultural University

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This page is a summary of: Thymol-based Dual Chemosensor for Optical Detection of Cu2+ and Pb2+ ions and Evaluation of its Toxicity Against Plant Growth Promoting Rhizobacteria, Letters in Organic Chemistry, March 2024, Bentham Science Publishers,
DOI: 10.2174/0115701786263410230928114953.
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