What is it about?

This is a review of the literature on the performance of FDG-PET and PET/CT in diagnosing osteomyelitis in the diabetic foot. A comparison to other imaging modalities, the use of different analysis methods, the impact of other co-existing conditions, such as hyperglycemia and long-term use of antibiotic drugs, and its impact on FDG-PET are reviewed. The added value of hybrid imaging techniques (PET/CT) is discussed.

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Why is it important?

In our review we show that FDG PET/CT has good sensitivity and specificity for diagnosing osteomyelitis in the diabetic foot. The sensitivity in detecting diabetic foot infections using Nuclear Medicine modalities increased in recent years, probably due to improved imaging techniques and the use of hybrid imaging. FDG PET/CT has several advantages compared to other imaging methods, including short acquisition time, high resolution, relatively lower radiation dose and better tolerability.

Perspectives

I hope this review will provide helpful information on the role of FDG PET/CT in this area and will help introduce this method to the diagnostic scheme in the evaluation of suspected infection in patients with diabetic foot.

Elite Arnon-Sheleg
Galilee Medical Center

Read the Original

This page is a summary of: Diabetic Foot Infection: The Role of PET/CT Imaging, Current Pharmaceutical Design, July 2018, Bentham Science Publishers, DOI: 10.2174/1381612824666180227095439.
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