What is it about?

The study is about the optimized synthesis ad encapsulation of Ocimum gatissimum essential oils in polymeric matrixes notably chitosan and its quaternized derivative N, N, N-trimethyl chitosan and further reduction into their nano sizes. the nanoparticles were characterized using microscopic and spectroscopic methods. the synthesized nanoparticles were also evaluated for their in-vitro release kinetics antioxidant, antimicrobial and anticancer properties.

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Why is it important?

The study has shown promising applications in the use of polymeric materials of nanosize for the targeted delivery of bioactive plant essential oils to an organism.

Perspectives

The study proposed a novel approach for the synthesis of Ocimum gratissimum essential oil encapsulated chitosan and N, N, N-trimethyl chitosan nanoparticles. The synthesized OGEO-loaded CS and TMC nanoparticles revealed their potential food and medical applications due to their wide solubility at different physiological pH ranges and their bioactivity as antioxidants as well as antibacterial and anticancer agents.

Confidence Onyebuchi
Cyprus International University

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This page is a summary of: Chitosan And N, N, N-Trimethyl Chitosan Nanoparticle Encapsulation Of Ocimum Gratissimum Essential Oil: Optimised Synthesis, In Vitro Release And Bioactivity, International Journal of Nanomedicine, September 2019, Taylor & Francis, DOI: 10.2147/ijn.s220202.
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