What is it about?

During follow-up, 55.2% patients and 33.9% healthy controls died. Social integration, physical activity and smoking predict survival in female coronary patients and physical activity predict all-cause mortality in healthy controls over 26 years.

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Why is it important?

This study began in 1991–1994 with a comprehensive baseline survey of women with cardiovascular disease and is unique in providing almost complete data on all-cause mortality over 26 years in patients (97.9%) and healthy controls (99.7%). The data analysis provided sufficient evidence for the importance of behavioral risk factors for all-cause mortality in this cohort of female CAD patients. In addition to the usual cardiological treatment of CAD, targeted behavioral therapy intervention to improve social integration is desirable in these patients.


In women with cardiovascular disease with smoking habits, smoking cessation and other preventive measures are needed to reduce all-cause mortality within 26 years. In healthy controls as in CAD patients, Physical activity was the most important predictor of survival. In women with CAD and in healthy women with sedentary lifestyles, programmes to increase physical activity are likely to be helpful.

Hans-Christian Deter
Charité, Medical Clinic, Divisionof Psychosomatic Medicine

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This page is a summary of: Behavioral factors predict all-cause mortality in female coronary patients and healthy controls over 26 years – a prospective secondary analysis of the Stockholm Female Coronary Risk Study, PLoS ONE, December 2022, PLOS,
DOI: 10.1371/journal.pone.0277028.
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