What is it about?
In insects, the developmental environment can shape the organism's biology for the rest of its life. Since mounting an immune response is a resource-intensive trait, general expectation from organisms growing in a resource-limited and competitive environments is that they would grow up to have inferior immune response than those who have developed in a resourceful developmental environment. This study shows that populations adapted to crowded larval environments for more than 240 generations show an improved evolved immune response against a gram-negative pathogen but not against a gram-positive pathogen.
Photo by Dominik Scythe on Unsplash
Why is it important?
The evolution of improved adult immunocompetence against gram-negative pathogens and not against gram-positive pathogen due to adaptation to crowded developmental environments show the possible correlation between developmental pathways and adult immune response pathways. This study warrants a much more detailed investigative study into the potential molecular mechanism in these pathways.
Read the Original
This page is a summary of: Evolution of pathogen-specific improved survivorship post-infection in populations of Drosophila melanogaster adapted to larval crowding, PLoS ONE, April 2021, PLOS, DOI: 10.1371/journal.pone.0250055.
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