What is it about?
We hypothesized that exposure to antibiotics would primarily target the daphnid microbiome with downstream effects on the host fitness. To test this hypothesis, we chronically exposed daphnids to an antibiotic drug ciprofloxacin, which resulted in decreased microbiome diversity. However, contrary to our hypothesis, at low concentrations ciprofloxacin stimulated growth and reproduction in the daphnids, with no adverse effects at high concentrations.
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Why is it important?
Although the microbiome was not directly involved in the growth-related responses to the ciprofloxacin exposure, the microbiome’s alterations suggest that exposure to any antimicrobials, which – unlike ciprofloxacin – do not stimulate antioxidant production, would result in gut dysbiosis with possible adverse effects on the host.
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This page is a summary of: Disparate effects of antibiotic-induced microbiome change and enhanced fitness in Daphnia magna, PLoS ONE, January 2020, PLOS, DOI: 10.1371/journal.pone.0214833.
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