What is it about?

The analysis of global gene expression compared to unbiased tissue proteomics analysis is a fascinating story of how fibrotic and angiogenic transformation results in disease

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Why is it important?

The s100a8 and s100a9 proteins triggered a series of downstream changes which alters cellular function and induces pterygium disease, as shown by genomic and proteomic analysis.

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This page is a summary of: Evaluation of Global Differential Gene and Protein Expression in Primary Pterygium: S100A8 and S100A9 as Possible Drivers of a Signaling Network, PLoS ONE, May 2014, PLOS,
DOI: 10.1371/journal.pone.0097402.
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