What is it about?
The NDDs are characterized by the progressive functional loss of neurons in the brain, causing cognitive impairment and motor neuron disability. Although multifactorial interactions are evident, BCs play an essential role in the pathogenesis and evolution of these diseases. The BCs in herbal/plant products play an important role in the protective effect against cognitive decline, respectively, NDDs. The use of plant or secondary metabolites (SMs) extracts as ingredients for medicines, cosmetics, and food is a topic of interest.
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Why is it important?
The utilization of plants being a concern at international level, to utilize plants in various fields, it is necessary to know their content in active principles, the use of advantageous extraction methods, and the purification of extracts and their use in different fields of activity. Representative of the category are BCs, bio-FLs which represent a group of SMs derived from plants, called polyphenolic compounds (PCs), recognized as antioxidants (AOs).
Perspectives
The BCs/FLs are found in certain fruits, vegetables, and other foods, including dark chocolate, and they have powerful antioxidant properties; being AOs, they can fight against the action of free radicals (FRs). The damaging action of FRs is believed to play a role in everything from NDDs. At the same time, AOs can even help the body cope with allergies and viruses. The BCs/FLs are a class of plant SMs that are part of the broader group of polyphenols (PPs). These SMs are found naturally in plants and are responsible for the vibrant colors of fruits, vegetables, and flowers. There are six subclasses of BCs/FLs: anthocyanidins, flavan-3-ols, flavanones, flavones, flavonols, and flavopolymers. They are powerful AOs, meaning they help fight OSs and protect cells from free radical damage. The BCs/FLs may also have anti-inflammatory, antiviral, antibacterial, and anti-carcinogenic effects.
habilitated doctor, chemist Monica BUTNARIU
University of Life Sciences "King Mihai I" from Timisoara
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This page is a summary of: Extraction of Bioactive Compounds in Herbal/Plant Products and Screening for Neuroactivities, June 2025, Taylor & Francis,
DOI: 10.1201/9781003467304-2.
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