What is it about?
The purpose of this research was to determine the serum levels of interleukin (IL)-8, IL-15, and tumor necrosis factor-a (TNF-a) among patients receiving mechanical ventilation for >48 hr and examine the relationships of these myokines to outcomes of patient delirium, muscle strength, activities of daily living (ADLs), duration of mechanical ventilation, and length of ICU stay.
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Why is it important?
Systemic inflammation and critical illness–induced cytokines have been implicated in the pathological onset and severity of ICU-Acquired Weakness
Perspectives
This was a pilot study to examine serum levels and test the intervention.
Dr Chris Winkelman
Case Western Reserve University
Read the Original
This page is a summary of: Associations Between Muscle-Related Cytokines and Selected Patient Outcomes in the ICU, Biological Research For Nursing, May 2014, SAGE Publications,
DOI: 10.1177/1099800414532709.
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