What is it about?
Our understanding of teratomagenesis is critically important for a medical field. We revealed that germinal center‐associated nuclear protein (GANP) is overexpressed in human testicular postpubertal‐type teratomas and established a novel GANP‐transgenic mouse to reveal teratomagenesis.
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Why is it important?
Although mouse models bearing teratoma have been established in the specific strains, we reported the novel model using C57BL/6 mice. Compared to 129/sv strain, our mice develop teratomas at a higher rate.
Perspectives
I hope that this article gives many researchers the critical information about teratomagenesis.
Kazuhiko Kuwahara
Kinki Daigaku
Read the Original
This page is a summary of: Testicular teratomagenesis from primordial germ cells with overexpression of germinal center‐associated nuclear protein, Cancer Science, December 2022, Wiley,
DOI: 10.1111/cas.15685.
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