What is it about?

Chronic myeloid leukemia (CML) and Non-Hodgkin lymphoma(NHL)are two different origins of hematological malignancies, which rarely occur at the same time. Moreover, NHL secondary to CML is common in T cell lymphoma, while NHL of B cell origin is rare.To our knowledge, it has no report for the primary gastric DLBCL (PG-DLBCL) occurring in CML. Here we reported a 63-year-old man of chronic phase (CP) CML associated with PG-DLBCL.

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Why is it important?

The patient with simultaneous occurrence of CML and PG-DLBCL is a very rare case, and this is first reported for the primary gastric DLBCL. Combination of Rituximab and lenalidomide is an effective therapy for the patients with this type of disease.

Perspectives

I hope that this article will increase the attention of clinicians about CML and be alert to the occurrence of other tumors.

Zhimei Cai

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This page is a summary of: A case of primary gastric diffuse large B-cell lymphoma occurring in chronic myeloid leukemia, OncoTargets and Therapy, July 2019, Dove Medical Press, DOI: 10.2147/ott.s212838.
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