What is it about?
The paper shows that the enzyme NMNATase binds closely related small molecules in distinctly different orientations.
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Why is it important?
We show that the product of another enzyme further downstream in the synthesis of dinucleotides can regulate the synthesis of NAD+ and how this is accomplished.
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This page is a summary of: Nicotinamide mononucleotide adenylyltransferase displays alternate binding modes for nicotinamide nucleotides, Acta Crystallographica Section D Biological Crystallography, September 2015, International Union of Crystallography,
DOI: 10.1107/s1399004715015497.
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