What is it about?
Inflammation is tightly associated with about the occurrence of one fourth cancers. The key pharmacutic targets for the interference of cancer development will potentially help to prolong survival term of the patients. This study suggests some molecular targets in cells.
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Why is it important?
This study revealed one key event in one kind of immune cells to control the inflammation which affected multiple cancer development.
Perspectives
To target the cellular events those we revealed in this study，it is possible to screen the effective small molecular chemicals or peptides to potentially treat multiple cancers in future.
Dr. Bin Wei
Shanghai University
Read the Original
This page is a summary of: HIPK2 phosphorylates HDAC3 for NF-κB acetylation to ameliorate colitis-associated colorectal carcinoma and sepsis, Proceedings of the National Academy of Sciences, July 2021, Proceedings of the National Academy of Sciences,
DOI: 10.1073/pnas.2021798118.
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