All Stories

  1. Impaired meningeal lymphatic drainage in Listeria monocytogenes infection
  2. ZNT1 and Zn2+ control TLR4 and PD-L1 endocytosis in macrophages to improve chemotherapy efficacy against liver tumor
  3. cFLIPS regulates alternative NLRP3 inflammasome activation in human monocytes
  4. The Oxysterol Receptor EBI2 Links Innate and Adaptive Immunity to Limit IFN Response and Systemic Lupus Erythematosus
  5. VEGFR-3 signaling restrains the neuron-macrophage crosstalk during neurotropic viral infection
  6. Advances in viral encephalitis: Viral transmission, host immunity, and experimental animal models
  7. Meningeal lymphatic vessels mediate neurotropic viral drainage from the central nervous system
  8. The Transcription of ZIP9 Is Associated With the Macrophage Polarization and the Pathogenesis of Hepatocellular Carcinoma
  9. AKT2 reduces IFNβ1 production to modulate antiviral responses and systemic lupus erythematosus
  10. FLT4/VEGFR3 activates AMPK to coordinate glycometabolic reprogramming with autophagy and inflammasome activation for bacterial elimination
  11. Targeting lysophospholipid acid receptor 1 and ROCK kinases promotes antiviral innate immunity
  12. HIPK2 phosphorylates HDAC3 for NF-κB acetylation to ameliorate colitis-associated colorectal carcinoma and sepsis
  13. M-CSF, IL-6, and TGF-β promote generation of a new subset of tissue repair macrophage for traumatic brain injury recovery
  14. LRCH1 deficiency enhances LAT signalosome formation and CD8+T cell responses against tumors and pathogens
  15. Targeting 7-Dehydrocholesterol Reductase Integrates Cholesterol Metabolism and IRF3 Activation to Eliminate Infection
  16. ER-localized Hrd1 ubiquitinates and inactivates Usp15 to promote TLR4-induced inflammation during bacterial infection
  17. PD1+CCR2+CD8+ T Cells Infiltrate the Central Nervous System during Acute Japanese Encephalitis Virus Infection
  18. YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis
  19. LRCH1 interferes with DOCK8-Cdc42–induced T cell migration and ameliorates experimental autoimmune encephalomyelitis
  20. STK4 regulates TLR pathways and protects against chronic inflammation–related hepatocellular carcinoma
  21. ADAP and SKAP55 deficiency suppresses PD-1 expression in CD8+ cytotoxic T lymphocytes for enhanced anti-tumor immunotherapy
  22. Activation of Vascular Endothelial Growth Factor Receptor-3 in Macrophages Restrains TLR4-NF-κB Signaling and Protects against Endotoxin Shock
  23. Immune adaptor ADAP in T cells regulates HIV-1 transcription and cell-cell viral spread via different co-receptors