What is it about?
Thyroid hormone is best known for regulating metabolism. We have discovered a role for the hormone in determining the structure of fish fin rays. Thyroid hormone is needed to shape the bony rays along the axis of the fin during both development and regeneration.
Featured Image
Photo by Worachat Sodsri on Unsplash
Why is it important?
Half of all living vertebrates are fish, and fish show great diversity in the structure and patterning of their fin rays. We have shown that thyroid hormone orchestrates the precise patterning of the fin rays, and across diverse species, the hormone helps regulate the shapes of ray segments and location of branches on the rays. This work suggests targets that may have been modulated during evolution to change the overall form of fin rays during the adaptation of different fishes.
Perspectives
Read the Original
This page is a summary of: Thyroid hormone regulates proximodistal patterning in fin rays, Proceedings of the National Academy of Sciences, May 2023, Proceedings of the National Academy of Sciences,
DOI: 10.1073/pnas.2219770120.
You can read the full text:
Contributors
The following have contributed to this page