What is it about?
SERS was employed to analyze the degree of degranulation of mast cells induced by low-intensity laser.High-quality SERS spectra of cell culture supernatants were obtained with the enhancement of silver nanoparticles.Combined with principal component analysis (PCA) and linear discriminant analysis (LDA), the degree of cell degranulation can be distinguished with high sensitivity and specificity.
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Why is it important?
This exploratory work demonstrates that the SERS technique combined with PCA-LDA algorithms possesses great promise for distinguishing the degree of degranulation of cells.
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This page is a summary of: Surface enhanced Raman spectroscopy analysis of mast cell degranulation induced by low-intensity laser, IET Nanobiotechnology, September 2019, the Institution of Engineering and Technology (the IET), DOI: 10.1049/iet-nbt.2019.0145.
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