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The U.S. Environmental Protection Agency’s (EPA) ToxCast program is testing a large library of Agency-relevant chemicals using in vitro high-throughput screening (HTS) approaches to support the development of improved toxicity prediction models. The history of the phased construction of EPA’s ToxCast library is reviewed, followed by a survey of the library contents from several different vantage points.

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This page is a summary of: ToxCast Chemical Landscape: Paving the Road to 21st Century Toxicology, Chemical Research in Toxicology, July 2016, American Chemical Society (ACS),
DOI: 10.1021/acs.chemrestox.6b00135.
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