What is it about?

mRNA vaccines played a key role in controlling the Covid19 pandemic. In this paper we review the basics behind this new vaccine platform and then focus on the challenges associated with the manufacturing mRNA vaccines at large scales.

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Why is it important?

The ability to ramp up manufacturing of mRNA vaccines is critical to guarantee access of the general population to immune protection during an infectious outbreak. Knowing the challenges and bottlenecks associated with mRNA manufacturing is key to any preparedness planning.

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This page is a summary of: mRNA vaccines manufacturing: Challenges and bottlenecks, Vaccine, April 2021, Elsevier, DOI: 10.1016/j.vaccine.2021.03.038.
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