What is it about?

Inflammation, Tear, Punctal plugs, Corticosteroids, restasis, dry eye treatment, profiling of cytokines, longitudinal study, human trials, Interferon, interleukins, TNFalpha, 3 weeks, management, non-pharmacological treatment, lacrimal outflow

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Why is it important?

As dry eye is so common and pervasive, almost everyone will have encountered a friend or family member who suffers from it. This may be the 40 year old bank officer who has been compelled to change his job because using the computer aggravated his condition, the 25 year old lady who has become socially withdrawn because of difficulty driving at night, or her 65 year old wheelchair-bound insomniac grandmother who required eyedrops every hour and has become clinically depressed.


Punctal plugs are available for clinical treatment of dry eye but they are still incompletely understood.

Prof Louis Tong
National University of Singapore

Read the Original

This page is a summary of: Effects of Punctal Occlusion on Clinical Signs and Symptoms and on Tear Cytokine Levels in Patients with Dry Eye, The Ocular Surface, April 2016, Elsevier,
DOI: 10.1016/j.jtos.2015.12.004.
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