What is it about?

Objectives Pain is a significant complaint of patients with postacute COVID-19 syndrome; however, little is known about the association between SARS-CoV-2 infection and pain. This study aimed to (1) examine the association between SARS-CoV-2 infection and low back pain (LBP) and (2) identify independent predictors of LBP among survivors of COVID-19. Methods This case-control study involved 878 participants aged ≥18 years. Data were collected from February 24 to April 7, 2022, in Bangladesh. LBP was measured using the musculoskeletal subscale of subjective health complaints produced by Eriksen et al. Descriptive analysis was performed to compute LBP prevalence and compare the prevalence across groups. Multiple logistic analyses helped to identify the predictors of LBP for survivors of COVID-19. Results Overall, 20% of participants reported LBP; however, the prevalence of LBP was significantly high among patients with postacute COVID-19 compared with their counterparts (24.4% vs 15.7%, P = 0.001). Regression analysis for all participants suggested that SARS-CoV-2 infection was independently associated with LBP (adjusted odds ratio 1.837, 95% confidence interval 1.253–2.692). However, moderate COVID-19 symptom (adjusted odds ratio 1.754, 95% confidence interval 0.984–3.126) was the only statistically significant predictor of LBP among postacute COVID-19 patients. Conclusion SARS-CoV-2 infection was associated with LBP, and moderate COVID-19 symptom was an independently associated factor of LBP. The health care facilities must be prepared to deal with the burden of LBP among patients with postacute COVID-19.

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Why is it important?

This study found a novel result: COVID-19 produce low back pain among post-acute COVID-19 patients


This comprehensive case-control study was conducted among community dwellers in Bangladesh. This is the first study in the world in its type.

Dr Mohammad Ali
La Trobe University

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This page is a summary of: SARS-CoV-2 infection is associated with low back pain: findings from a community-based case-control study, International Journal of Infectious Diseases, September 2022, Elsevier, DOI: 10.1016/j.ijid.2022.05.050.
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