All Stories

  1. Physics and mathematics help us better understand how the immune system selects and treats targets

    Article • Antibodies, June 2022, MDPI AG

    József Prechl

  2. Measurement of antibody activity in blood serum using protein chips

    Article • Sensors, May 2022, MDPI AG

    József Prechl

  3. The Binding Landscape of Serum Antibodies: How Physical and Mathematical Concepts can Advance Systems Immunology

    Article • April 2022, MDPI AG

    József Prechl

  4. Absolute quantitation of serum antibody reactivity using the Richards growth model for antigen microspot titration

    Article • October 2021, Cold Spring Harbor Laboratory Press

    József Prechl

  5. Current blood antibody testing is not quantitative even if it is called so

    Article • Biologia Futura, February 2021, Springer Science + Business Media

    József Prechl

  6. Immunological cells and mechanisms contributing to memory in the immune system

    Article • Vaccines, February 2021, MDPI AG

    József Prechl

  7. Antibodies in blood form a network, which can be modeled using physics and network science

    Article • Antibodies, May 2020, MDPI AG

    József Prechl

  8. Network organization of antibody interactions in sequence and structure space: the RADARS model

    Article • October 2018, Cold Spring Harbor Laboratory Press

    József Prechl

  9. Quantitative Network Organization of Interactions Emerging from the Evolution of Sequence and Structure Space of Antibodies: the RADARS Model

    Article • October 2018, MDPI AG

    József Prechl

  10. Thermodynamic projection of the antibody interaction network: The fountain energy landscape of molecular interaction systems

    Article • F1000Research, February 2018, Faculty of 1000, Ltd.

    József Prechl

  11. Examining molecular networks in multicellular organisms

    Article • F1000Research, November 2017, Faculty of 1000, Ltd.

    József Prechl

  12. Thermodynamic projection of the antibody interaction network: The fountain energy landscape of molecular interaction systems

    Article • F1000Research, September 2017, Faculty of 1000, Ltd.

    József Prechl

  13. The Generalized Quantitative Model of antibody homeostasis: maintenance of global antibody equilibrium by effector functions

    Article • July 2017, Cold Spring Harbor Laboratory Press

    József Prechl

  14. Detection of red blood cell surface antigens by probe-triggered cell collision and flow retardation in an autonomous microfluidic system

    Article • Scientific Reports, April 2017, Springer Science + Business Media

    József Prechl

  15. Visualization of complex antibody interactions based on physico-chemical interpretation

    Article • April 2017, Cold Spring Harbor Laboratory Press

    József Prechl

  16. A generalized quantitative antibody homeostasis model: antigen saturation, natural antibodies and a quantitative antibody network

    Article • Clinical & Translational Immunology, February 2017, Wiley

    József Prechl

  17. A generalized quantitative antibody homeostasis model: regulation of B-cell development by BCR saturation and novel insights into bone marrow function

    Article • Clinical & Translational Immunology, February 2017, Wiley

    József Prechl

  18. A generalized quantitative antibody homeostasis model: regulation of B-cell development by BCR saturation and novel insights into bone marrow function

    Article • July 2016, Cold Spring Harbor Laboratory Press

    József Prechl

  19. A generalized quantitative antibody homeostasis model: antigen saturation, natural antibodies and a quantitative antibody network

    Article • July 2016, Cold Spring Harbor Laboratory Press

    József Prechl

  20. Characterization of NF-κB Reporter U937 Cells and Their Application for the Detection of Inflammatory Immune-Complexes

    Article • PLoS ONE, May 2016, PLOS

    József Prechl

  21. Measurement of cell binding to solid phase antibodies by plasmon resonance

    Article • Clinical & Experimental Immunology, May 2016, Wiley

    József Prechl

  22. Serological and Genetic Evidence for Altered Complement System Functionality in Systemic Lupus Erythematosus: Findings of the GAPAID Consortium

    Article • PLoS ONE, March 2016, PLOS

    József Prechl

  23. Label-free Microfluidic Sensing by Detection of Interaction-triggered Change in Blood Flow Characteristics

    Article • Procedia Engineering, January 2016, Elsevier

    József Prechl

  24. Monovalent Fc receptor blockade by an anti-Fc  receptor/albumin fusion protein ameliorates murine ITP with abrogated toxicity

    Article • Blood, October 2015, American Society of Hematology

    József Prechl

  25. The endothelial deprotection hypothesis for lupus pathogenesis: the dual role of C1q as a mediator of clearance and regulator of endothelial permeability

    Article • F1000Research, May 2015, Faculty of 1000, Ltd.

    József Prechl

  26. Lupus pathogenesis and the vascular endothelium

    Article • F1000Research, January 2015, Faculty of 1000, Ltd.

    József Prechl

  27. Non-CpG Oligonucleotides Exert Adjuvant Effects by Enhancing Cognate B Cell-T Cell Interactions, Leading to B Cell Activation, Differentiation, and Isotype Switching

    Article • Journal of Immunology Research, January 2015, Hindawi Publishing Corporation

    József Prechl

  28. Exploiting fluorescence for multiplex immunoassays on protein microarrays

    Article • Methods and Applications in Fluorescence, August 2014, Institute of Physics Publishing

    József Prechl

  29. Introduction

    Article • Immunology Letters, August 2014, Elsevier

    József Prechl

  30. Coadministration of antigen-conjugated and free CpG: Effects of in vitro and in vivo interactions in a murine model

    Article • Immunology Letters, August 2014, Elsevier

    József Prechl

  31. Bead Arrays for Antibody and Complement Profiling Reveal Joint Contribution of Antibody Isotypes to C3 Deposition

    Article • PLoS ONE, May 2014, PLOS

    József Prechl

  32. Built-in adjuvanticity of genetically and protein-engineered chimeric molecules for targeting of influenza A peptide epitopes

    Article • Immunologic Research, February 2014, Springer Science + Business Media

    József Prechl

  33. Recognition of new citrulline-containing peptide epitopes by autoantibodies producedin vivoandin vitroby B cells of rheumatoid arthritis patients

    Article • Immunology, January 2014, Wiley

    Gabriella Sarmay, József Prechl

  34. Application of Fluorescent Monocytes for Probing Immune Complexes on Antigen Microarrays

    Article • PLoS ONE, September 2013, PLOS

    József Prechl

  35. Generation of Gene-Engineered Chimeric DNA Molecules for Specific Therapy of Autoimmune Diseases

    Article • Human Gene Therapy Methods, December 2012, Mary Ann Liebert Inc

    József Prechl

  36. Immune Complex Signatures of Patients with Active and Inactive SLE Revealed by Multiplex Protein Binding Analysis on Antigen Microarrays

    Article • PLoS ONE, September 2012, PLOS

    József Prechl

  37. FcRn Overexpression in Transgenic Mice Results in Augmented APC Activity and Robust Immune Response with Increased Diversity of Induced Antibodies

    Article • PLoS ONE, April 2012, PLOS

    József Prechl

  38. Exacerbation of collagen induced arthritis by Fcγ receptor targeted collagen peptide due to enhanced inflammatory chemokine and cytokine production

    Article • Biologics Targets & Therapy, April 2012, Taylor & Francis

    József Prechl, Gabriella Sarmay

  39. Life on a microarray: assessing live cell functions in a microarray format

    Article • Cellular and Molecular Life Sciences, March 2012, Springer Science + Business Media

    József Prechl

  40. Complementing antibody profiles: Assessing antibody function on antigen microarrays

    Article • Immunology Letters, March 2012, Elsevier

    József Prechl

  41. Introduction

    Article • Immunology Letters, March 2012, Elsevier

    József Prechl

  42. Characterization of factors influencing on-chip complement activation to optimize parallel measurement of antibody and complement proteins on antigen microarrays

    Article • Journal of Immunological Methods, January 2012, Elsevier

    József Prechl

  43. Facing challenges in Proteomics today and in the coming decade: Report of Roundtable Discussions at the 4th EuPA Scientific Meeting, Portugal, Estoril 2010

    Article • Journal of Proteomics, December 2011, Elsevier

    József Prechl

  44. Application of Monoclonal Antibody Therapies in Autoimmune Diseases

    Article • November 2011, IntechOpen

    József Prechl

  45. The Use of Antigen Microarrays in Antibody Profiling

    Article • November 2011, Springer Science + Business Media

    József Prechl

  46. Modulation of the humoral immune response by targeting CD40 and FcγRII/III; delivery of soluble but not particulate antigen to CD40 enhances antibody responses with a Th1 bias

    Article • Molecular Immunology, October 2011, Elsevier

    József Prechl

  47. Elimination of autoreactive B cells in humanized SCID mouse model of SLE

    Article • European Journal of Immunology, September 2011, Wiley

    József Prechl

  48. Functional serum antibody profiles in autoimmune disease diagnostics

    Article • Molecular Immunology, August 2011, Elsevier

    József Prechl

  49. Transgenic expression of bovine neonatal Fc receptor in mice boosts immune response and improves hybridoma production efficiency without any sign of autoimmunity

    Article • Immunology Letters, June 2011, Elsevier

    József Prechl

  50. Humanized SCID Mice Models of SLE

    Article • Current Pharmaceutical Design, May 2011, Bentham Science Publishers

    József Prechl

  51. Targeting Dendritic Cells with Carbon Magnetic Nanoparticles Made by Dense-Medium Plasma Technology

    Article • October 2010, Wiley

    József Prechl

  52. Progression of lupus-like disease drives the appearance of complement-activating IgG antibodies in MRL/lpr mice

    Article • Rheumatology, August 2010, Oxford University Press (OUP)

    József Prechl

  53. Differential expression and function of complement receptor type 1 (CD35) and 2 (CD21) on human B lymphocytes

    Article • Molecular Immunology, August 2010, Elsevier

    József Prechl

  54. Dendritic Cells in Chronic Mycobacterial Granulomas Restrict Local Anti-Bacterial T Cell Response in a Murine Model

    Article • PLoS ONE, July 2010, PLOS

    József Prechl

  55. Re-establishing tolerance to DNA in humanized and murine models of SLE

    Article • Autoimmunity Reviews, May 2010, Elsevier

    József Prechl

  56. Modulation of immune response by combined targeting of complement receptors and low-affinity Fcγ receptors

    Article • Immunology Letters, May 2010, Elsevier

    József Prechl

  57. Antigen microarrays: descriptive chemistry or functional immunomics?

    Article • Trends in Immunology, April 2010, Elsevier

    József Prechl

  58. Anti-factor B autoantibody in dense deposit disease

    Article • Molecular Immunology, April 2010, Elsevier

    József Prechl

  59. Using carbon magnetic nanoparticles to target, track, and manipulate dendritic cells

    Article • Journal of Immunological Methods, April 2010, Elsevier

    József Prechl

  60. A novel, complement-mediated way to enhance the interplay between macrophages, dendritic cells and T lymphocytes

    Article • Molecular Immunology, December 2009, Elsevier

    József Prechl

  61. CD16/32-specific biotinylated 2.4G2 single-chain Fv complexed with avidin-FITC enhances FITC-specific humoral immune response in vivo in a CD16-dependent manner

    Article • International Immunology, November 2009, Oxford University Press (OUP)

    József Prechl

  62. Transient decomplementation of mice delays onset of experimental autoimmune encephalomyelitis and impairs MOG-specific T cell response and autoantibody production

    Article • Molecular Immunology, November 2009, Elsevier

    József Prechl

  63. Generation of functional antibody profiles using complement deposition data from protein arrays

    Article • Molecular Immunology, September 2009, Elsevier

    József Prechl

  64. Identification and characterization of a factor B autoantibody in membranoproliferative glomerulonephritis type II

    Article • Molecular Immunology, September 2009, Elsevier

    József Prechl

  65. Anti-DNA antibodies with IgG isotype override early regulation points of the complement cascade and induce abundant C3 generation

    Article • Molecular Immunology, September 2009, Elsevier

    József Prechl

  66. Expression and role of CR1 and CR2 on B and T lymphocytes under physiological and autoimmune conditions

    Article • Molecular Immunology, September 2009, Elsevier

    József Prechl

  67. Synthesis of hepcidin derivatives in order to develop standards for immune adsorption method

    Article • Journal of Peptide Science, April 2009, Wiley

    József Prechl

  68. Egg composition in relation to social environment and maternal physiological condition in the collared flycatcher

    Article • Behavioral Ecology and Sociobiology, February 2009, Springer Science + Business Media

    Professor János Török, Dr Kathryn Arnold, József Prechl

  69. Detection of Complement Activation on Antigen Microarrays Generates Functional Antibody Profiles and Helps Characterization of Disease-Associated Changes of the Antibody Repertoire

    Article • The Journal of Immunology, November 2008, The American Association of Immunologists

    József Prechl

  70. Advantage of parallel measurement of antibody binding and complement activation on antigen chips

    Article • PROTEOMICS, July 2008, Wiley

    József Prechl

  71. B lymphocytes and macrophages release cell membrane deposited C3-fragments on exosomes with T cell response-enhancing capacity☆

    Article • Molecular Immunology, April 2008, Elsevier

    József Prechl

  72. Novel roles for murine complement receptors type 1 and 2

    Article • Immunology Letters, March 2008, Elsevier

    József Prechl

  73. Novel roles for murine complement receptors type 1 and 2

    Article • Immunology Letters, March 2008, Elsevier

    József Prechl

  74. An antibody-based construct carrying DNA-mimotope and targeting CR1(CD35) selectively suppresses human autoreactive B-lymphocytes

    Article • Immunology Letters, March 2008, Elsevier

    József Prechl

  75. Physiological up-regulation of inhibitory receptors Fc RII and CR1 on memory B cells is lacking in SLE patients

    Article • International Immunology, January 2008, Oxford University Press (OUP)

    József Prechl

  76. On-chip complement activation for functional profiling of serum antibodies on antigen microarrays

    Article • Molecular Immunology, September 2007, Elsevier

    József Prechl

  77. On-chip complement activation is a suitable technique for the simultaneous detection of the presence and complement activating properties of autoantibodies

    Article • Molecular Immunology, September 2007, Elsevier

    József Prechl

  78. Altered Expression of Fc  and Complement Receptors on B Cells in Systemic Lupus Erythematosus

    Article • Annals of the New York Academy of Sciences, June 2007, Wiley

    József Prechl

  79. Possible therapeutic applications of single-chain antibodies in systemic autoimmune diseases

    Article • Expert Opinion on Biological Therapy, May 2007, Informa Healthcare

    József Prechl

  80. Novel roles of CR1/2 on B lymphocytes

    Article • Molecular Immunology, January 2007, Elsevier

    József Prechl

  81. PROHEPCIDIN LEVELS DURING HUMAN PERINATAL ADAPTATION

    Article • Pediatric Hematology and Oncology, January 2007, Taylor & Francis

    József Prechl

  82. On-chip Complement Activation Adds an Extra Dimension to Antigen Microarrays

    Article • Molecular & Cellular Proteomics, October 2006, American Society for Biochemistry & Molecular Biology (ASBMB)

    József Prechl

  83. Maternal immunoglobulin concentration in Collared Flycatcher (Ficedula albicollis) eggs in relation to parental quality and laying order

    Article • Functional Ecology, October 2006, Wiley

    József Prechl, Professor János Török

  84. Immunization with a DNA chimeric molecule encoding a hemagglutinin peptide and a scFv CD21-specific antibody fragment induces long-lasting IgM and CTL responses to influenza virus

    Article • Vaccine, March 2006, Elsevier

    József Prechl

  85. The role of CR2 in autoimmunity

    Article • Autoimmunity, January 2006, Taylor & Francis

    József Prechl

  86. Regulation of B-cell activation by complement receptors CR1 (CD35) and CR2 (CD21)—possible involvement in the pathogenesis of autoimmune diseases

    Article • Autoimmunity Reviews, November 2004, Elsevier

    József Prechl

  87. Novel monoclonal antibodies against mouse C3 interfering with complement activation: description of fine specificity and applications to various immunoassays

    Article • Molecular Immunology, March 2004, Elsevier

    József Prechl

  88. Regulation of B-Cell Activation by Complement Receptors CD21 and CD35

    Article • Current Pharmaceutical Design, September 2003, Bentham Science Publishers

    József Prechl

  89. Targeting with scFv: immune modulation by complement receptor specific constructs

    Article • Journal of Molecular Recognition, September 2003, Wiley

    József Prechl

  90. Mucosal type mast cells express complement receptor type 2 (CD21)

    Article • Immunology Letters, June 2002, Elsevier

    József Prechl

  91. Complement Receptor Type 1 (CD35) Mediates Inhibitory Signals in Human B Lymphocytes

    Article • The Journal of Immunology, March 2002, The American Association of Immunologists

    József Prechl

  92. Modeling the presentation of C3d-coated antigen by B lymphocytes: enhancement by CR1/2-BCR co-ligation is selective for the co-ligating antigen

    Article • International Immunology, March 2002, Oxford University Press (OUP)

    József Prechl

  93. Immunomodulatory functions of murine CR1/2

    Article • Immunopharmacology, August 2000, Elsevier

    József Prechl

  94. H1 histamine receptor antagonist inhibits constitutive growth of Jurkat T cells and antigen-specific proliferation of ovalbumin-specific murine T cells

    Article • Seminars in Cancer Biology, February 2000, Elsevier

    József Prechl

  95. Inhibition of advanced glycated end-products

    Article • Postgraduate Medical Journal, July 1999, BMJ

    József Prechl

  96. Targeting of influenza epitopes to murine CR1/CR2 using single-chain antibodies

    Article • Immunopharmacology, May 1999, Elsevier

    József Prechl

  97. Alterations in enzymatic antioxidant defence in diabetes mellitus - a rational approach

    Article • Postgraduate Medical Journal, January 1999, BMJ

    József Prechl

  98. Ultrastructural localization of Hsp-72 examined with a new polyclonal antibody raised against the truncated variable domain of the heat shock protein

    Article • Cell Stress and Chaperones, January 1999, Springer Science + Business Media

    József Prechl

  99. A further link between innate and adaptive immunity: C3 deposition on antigen-presenting cells enhances the proliferation of antigen-specific T cells.

    Article • International Immunology, December 1998, Oxford University Press (OUP)

    József Prechl

  100. Targeting of influenza epitopes to murine CR1,2 using SCFV antibodies

    Article • Molecular Immunology, April 1998, Elsevier

    József Prechl

  101. Coordination of Adaptive Immune Responses by C3

    Article • Springer Science + Business Media

    József Prechl

  102. The Role of the Complement System in the Pathogenesis of Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

    Article • Springer Science + Business Media

    József Prechl

  103. Murine CR1/2 Targeted Antigenized Single-Chain Antibody Fragments Induce Transient Low Affinity Antibodies and Negatively Influence an Ongoing Immune Response

    Article • Springer Science + Business Media

    József Prechl