All Stories

  1. Indole Derivatives as Anti-Tubercular Agents: An Overview on their Synthesis and Biological Activities
  2. Synthesis of 2-substituted Furo[3,2-b]pyridines Under Pd/C-Cu Catalysis Assisted by Ultrasound: Their Evaluation as Potential Cytotoxic Agents
  3. Urea as an ammonia surrogate in the Hantzsch’s synthesis of polyhydroquinolines /1,4-dihydropyridines under green reaction conditions
  4. Ultrasound Assisted Synthesis of 2-Substituted Benzofurans via One-Pot and Sequential Method: Their In Vitro Evaluation
  5. One-Pot Synthesis of 5-(Het)Aryl 8-Aminoquinoline Amide Derivatives as Potential Antibacterial / Cytotoxic Agents
  6. Lemon Juice as a Biocatalyst Under Ultrasound Irradiation: Synthesis and Pharmacological Evaluation of 2-amino 1,3,4-thiadiazoles
  7. Lemon Juice Mediated Synthesis of 3-Substituted Quinazolin-4(3H)-Ones and their Pharmacological Evaluation
  8. Synthesis of 2-Substituted 4-Arylidene-5(4H)-oxazolones as Potential Cytotoxic Agents in the Presence of Lemon Juice as a Biocatalyst
  9. Lemon Juice Mediated Reaction under Ultrasound Irradiation: Synthesis of Indolofuroquinoxalines as Potential Anticancer Agents
  10. Ultrasound-assisted Synthesis of 6-substituted indolo[2,3-b]quinolines: their Evaluation as Potential Cytotoxic Agents
  11. Ultrasound Assisted One-pot and Sequential Synthesis of 3-methyleneisoindolin- 1-ones and their in vitro Evaluation
  12. Synthesis and Antibacterial/Antitubercular/Antioxidant Activities of Compounds Containing Fluoroquinolone Ring Linked to a 4-thiazolidinone Moiety
  13. 2-Amino Analogues of Alkynyl Substituted 1,4-dihydropyrimidine: Their Synthesis and Evaluation as Potential Antimicrobial/Cytotoxic Agents
  14. Ultrasound Assisted Cu-catalyzed Synthesis of 1,2-Disubstituted Benzimidazoles as Potential Antibacterial Agents
  15. Ultrasound Assisted Synthesis of 3,4-Diyne Substituted Isocoumarin Derivatives: Identification of Potential Cytotoxic Agents
  16. Ultrasound Assisted Synthesis of Quinoline Derivatives in the Presence of SnCl2·2H2O as a Precatalyst in Water: Evaluation of their Antibacterial Activities
  17. Mefenamic acid based novel indole analogues: Their synthesis and anti-proliferative effects
  18. A new reaction to afford complex indole derivatives
  19. FeCl3/Ultrasound Mediated Reaction of 2-aminothiophenol with Aldehydes in Water: Synthesis of 2-substituted Benzothiazoles of Pharmacological Interest
  20. ChemInform Abstract: New MCR Based on Intramolecular Heck Reaction under Aerobic Conditions: A Direct Access to Cytotoxic Fused N-Heterocycles.
  21. Creation of molecular complexities via a new Cu-catalyzed cascade reaction: a direct access to novel 2,2′-spirobiindole derivatives
  22. A Pd(ii)-catalyzed C–H activation approach to densely functionalized N-heteroaromatics related to neocryptolepine and their evaluation as potential inducers of apoptosis
  23. A catalyst-free rapid, practical and general synthesis of 2-substituted quinazolin-4(3H)-ones leading to luotonin B and E, bouchardatine and 8-norrutaecarpine
  24. Pd-catalyzed isocyanide insertion/nucleophilic attack by indole C-3/desulfonylation in the same pot: a direct access to indoloquinolines of pharmacological interest
  25. Quinoxaline: a new directing group for ortho C–H alkenylation / intramolecular ortho C–H cycloamination under open air leading to bioactive polynuclear N-heteroarenes
  26. A greener approach towards double heteroarylation of N, O and S nucleophiles: synthesis of bioactive polynuclear fused N-heteroarenes
  27. A metal catalyst-free and one-pot synthesis of (3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)methanol derivatives in water
  28. A Pd-catalyzed direct entry to 11-substituted 6H-isoindolo[2,1-a]indol-6-one derivatives as potential anticancer agents
  29. 1,2,3-Triazoles derived from olanzapine: their synthesis via an ultrasound assisted CuAAC method and evaluation as inhibitors of PDE4B
  30. PMA-SiO2–Mediated MCR in PEG-400: A Greener aza-Friedel–Crafts Reaction Leading to 3-Arylmethyl/Diarylmethyl Indoles
  31. Pd/C-mediated Synthesis of 2,3-diyne-1,4-naphthoquinone Derivatives via dual C-C Bond Forming Reaction in a Single Step
  32. New MCR based on intramolecular Heck reaction under aerobic conditions: a direct access to cytotoxic fused N-heterocycles
  33. ChemInform Abstract: A Direct Access to Bioactive Fused N-Heterocyclic Acetic Acid Derivatives.
  34. Ligand-free MCR for linking quinoxaline framework with a benzimidazole nucleus: a new strategy for the identification of novel hybrid molecules as potential inducers of apoptosis
  35. TFAA/H3PO4mediated unprecedented N-acylation of carbazoles leading to small molecules possessing anti-proliferative activities against cancer cells
  36. ChemInform Abstract: Amberlyst-15-Catalyzed Synthesis of 2-Substituted 1,3-Benzazoles in Water under Ultrasound.
  37. Revisiting Iodine-mediated N-tert-Butoxycarbonylation of Amines
  38. Pd/ligand-free synthesis of thienopyranones via Cu-catalyzed coupling-cyclization in PEG 400 under ultrasound
  39. A direct access to bioactive fused N-heterocyclic acetic acid derivatives
  40. Construction of phenoxazine rings containing nitro and sulfonic acid groups leading to phenoxazine-3-sulfonamide derivatives: their evaluation as novel and potential insulin secretagogues
  41. A Pd-based regioselective strategy to indole-1,2-fused 8- and 9-membered rings: their evaluation as potential scaffolds for apoptosis in zebrafish
  42. Zebrafish based strategy for the identification of a potential pharmacophore for apoptosis: a greener CuAAC approach for novel 1,2,3-triazoles derived from mefenamic acid
  43. A simple access to N-(un)substituted isoquinolin-1(2H)-ones: unusual formation of regioisomeric isoquinolin-1(4H)-ones
  44. Reactions of salicylaldehydes with activated terminal alkynes in aqueous media: synthesis of 3-substituted 4-hydroxy chromenes as potential cytotoxic agents
  45. Synthesis of substituted pyrroles via Amberlyst-15 mediated MCR under ultrasound
  46. Catalyst / Surfactant Free Chemoselective Acylation of Amines in Water
  47. ChemInform Abstract: IBX Mediated Reaction of β-Enamino Esters with Allylic Alcohols: A One-Pot Metal Free Domino Approach to Functionalized Pyridines.
  48. Medicinal Chemistry of Quinolines As Emerging Anti-inflammatory Agents: An Overview
  49. ChemInform Abstract: Pd-Mediated Construction of a Cyclopentane Ring Fused with Indoles.
  50. ChemInform Abstract: Pd/C-Mediated Synthesis of (Z)-3-Alkylidenephthalides of Potential Pharmacological Interest.
  51. ChemInform Abstract: Pd/C-Cu-Mediated Direct and One-Pot Synthesis of γ-Ylidene Butenolides.
  52. ChemInform Abstract: Pd/C-Mediated Depropargylation of Propargyl Ethers/Amines in Water.
  53. Quinolines: a new hope against inflammation
  54. ChemInform Abstract: A Greener Synthesis of 1,8-Dioxo-octahydroxanthene Derivatives under Ultrasound.
  55. Pd/C-mediated depropargylation of propargyl ethers/amines in water
  56. ChemInform Abstract: Pd-Mediated Functionalization of Polysubstituted Pyrroles: Their Evaluation as Potential Inhibitors of PDE4.
  57. Ligand/PTC-free intramolecular Heck reaction: synthesis of pyrroloquinoxalines and their evaluation against PDE4/luciferase/oral cancer cell growth in vitro and zebrafish in vivo
  58. IBX mediated reaction of β-enamino esters with allylic alcohols: a one pot metal free domino approach to functionalized pyridines
  59. Catalysis by Amberlyst-15 under ultrasound in water: a green synthesis of 1,2,4-benzothiadiazine-1,1-dioxides and their spiro derivatives
  60. Crystal Structure Analysis of Ethyl 7-Phenyl-5- p-tolylpyrazolo[1,5-a]pyrimidine-3-carboxylate
  61. ChemInform Abstract: Construction of a Quinoline Ring via a 3-Component Reaction in Water: Crystal Structure Analysis and H-Bonding Patterns of a 2-Aryl Quinoline.
  62. ChemInform Abstract: A New Approach to Construct a Fused 2-Ylidene Chromene Ring: Highly Regioselective Synthesis of Novel Chromeno Quinoxalines.
  63. ChemInform Abstract: Solvent Effect on Copper-Catalyzed Azide-Alkyne Cycloaddition (CuAAC): Synthesis of Novel Triazolyl Substituted Quinolines as Potential Anticancer Agents.
  64. ChemInform Abstract: Catalysis by Molecular Iodine: A Rapid Synthesis of 1,8-Dioxo-octahydroxanthenes and Their Evaluation as Potential Anticancer Agents.
  65. ChemInform Abstract: N-Heterocyclic Carbene-Mediated Hydroacylation-Sonogashira/Heck/Suzuki Coupling in a Single Pot: A New Cascade Reaction.
  66. Iodine catalyzed four-component reaction: a straightforward one-pot synthesis of functionalized pyrroles under metal-free conditions
  67. ChemInform Abstract: Yb(OTf)3Catalyzed New Cascade Reaction: A Facile Assembly of Fused Quinazolinones.
  68. ChemInform Abstract: Isocoumarin and Its Derivatives: Their Synthesis and Applications
  69. Isocoumarin and Its Derivatives: An Overview on their Synthesis and Applications
  70. ChemInform Abstract: Synthesis of Dipeptidyl Peptidase-4 Inhibitors: A Brief Overview
  71. ChemInform Abstract: AlCl3-Induced (Hetero)arylation of Thienopyrimidine Ring: A New Synthesis of 4-Substituted Thieno[2,3-d]pyrimidines.
  72. Synthesis of dipeptidyl peptidase-4 inhibitors: a brief overview
  73. A simple synthesis of aminopyridines: use of amides as amine source
  74. Amberlyst-15: a mild, efficient and reusable heterogeneous catalyst for N-tert-butoxycarbonylation of amines
  75. Medicinal Chemistry Approaches for Glucokinase Activation to Treat Type 2 Diabetes
  76. Pd/C-Mediated synthesis of indoles in water
  77. Recent advances in glucokinase activators for the treatment of type 2 diabetes
  78. ChemInform Abstract: A New Synthesis of 2-(Hetero)aryl-Substituted Pyrazines.
  79. Regioselective alkynylation followed by Suzuki coupling of 2,4-dichloroquinoline: Synthesis of 2-alkynyl-4-arylquinolines
  80. ChemInform Abstract: Microwave-Accelerated Wittig Olefination of β-Chloroacroleins.
  81. ChemInform Abstract: HDL Therapeutics for the Treatment of Atherosclerosis: A Brief Overview of the Synthetic Approaches.
  82. A new synthesis of 2-(hetero)aryl-substituted pyrazines
  83. Vanilloid Receptor Antagonists: Emerging Class of Novel Anti-Inflammatory Agents for Pain Management
  84. Medicinal chemistry approaches to the inhibition of dipeptidyl peptidase-4 for the treatment of type 2 diabetes
  85. Microwave-accelerated Wittig olefination of β-chloroacroleins
  86. ChemInform Abstract: Recent Advances on Phosphodiesterase 4 Inhibitors for the Treatment of Asthma and Chronic Obstructive Pulmonary Disease
  87. Emerging Drug Candidates of Dipeptidyl Peptidase IV (DPP IV) Inhibitor Class for the Treatment of Type 2 Diabetes
  88. HDL Therapeutics for the treatment of atherosclerosis: a brief overview of the synthetic approaches
  89. ChemInform Abstract: Synthesis of 2-Alkynylquinolines from 2-Chloro and 2,4-Dichloroquinoline via Pd/C-Catalyzed Coupling Reaction in Water.
  90. Synthesis of imidazol-1-yl-acetic acid hydrochloride: A key intermediate for zoledronic acid
  91. Recent Advances on Phosphodiesterase 4 Inhibitors for the Treatment of Asthma and Chronic Obstructive Pulmonary Disease
  92. A Cross-Metathesis Approach to the Synthesis of Key Precursor of the Macrolide Core of Rhizoxin D
  93. Synthesis of 2-alkynylquinolines from 2-chloro and 2,4-dichloroquinoline via Pd/C-catalyzed coupling reaction in water
  94. Synthesis of (S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile: A key intermediate for dipeptidyl peptidase IV inhibitors
  95. Revisiting the reaction of β-chloroacroleins with 2-aminophenol: a new observation
  96. Pd/C-catalyzed alkynylation of β-chloroacroleins
  97. Tandem C—C Coupling — Intramolecular Acetylenic Schmidt Reaction under Pd/C—Cu Catalysis.
  98. Pd-Mediated Synthesis of Substituted Benzenes Fused with Carbocycle/Heterocycle.
  99. Facile Synthesis of Substituted Thiophenes via Pd/C-Mediated Sonogashira Coupling in Water.
  100. Tandem versus Single C—C Bond Forming Reaction under Palladium—Copper Catalysis: Regioselective Synthesis of α-Pyrones Fused with Thiophene.
  101. One-Pot Synthesis of 2-Substituted Furo[3,2-c]quinolines via Tandem Coupling—Cyclization under Pd/C-Copper Catalysis.
  102. A Concise Asymmetric Route to the Antibiotic Macrolides Patulolide A (I) and Pyrenophorin (II).
  103. Pd-mediated synthesis of substituted benzenes fused with carbocycle/heterocycle
  104. HDL Elevators and Mimetics - Emerging Therapies for Atherosclerosis
  105. One-pot synthesis of 2-substituted furo[3,2-c]quinolines via tandem coupling–cyclization under Pd/C-copper catalysis
  106. Alkynylation of Halo Pyrimidines under Pd/C—Copper Catalysis: Regioselective Synthesis of 4- and 5-Alkynylpyrimidines.
  107. A concise asymmetric route to the antibiotic macrolides patulolide A and pyrenophorin
  108. Stereoselective synthesis of the C1–C10 fragment of rhizoxin D
  109. Alkynylation of halo pyrimidines under Pd/C–copper catalysis: regioselective synthesis of 4- and 5-alkynylpyrimidines
  110. Pd/C-Mediated Coupling of Aryl Halides with Terminal Alkynes in Water.
  111. Regio- and Stereospecific Synthesis of Novel 3-Enynyl-Substituted Thioflavones/Flavones Using a Copper-Free Palladium-Catalyzed Reaction.
  112. Synthesis and Crystal Structure of 2-(1-Methyl-1H-3-indolyl)nicotinonitrile
  113. Pd/C-mediated coupling of aryl halides with terminal alkynes in water
  114. Synthesis of 2-Substituted Indoles via Pd/C-Catalyzed Reaction in Water.
  115. A Direct Access to 3-(2-Oxoalkyl)indoles via Aluminum Chloride Induced C—C Bond Formation.
  116. Palladium-Mediated Stereospecific Synthesis of 3-Enynyl Substituted Thioflavones/Flavones.
  117. A Direct Access to 3-(2-Oxoalkyl)indoles via Aluminum Chloride Induced C−C Bond Formation†
  118. Pd/C-Mediated Synthesis of 2-Substituted Benzo[b]furans/nitrobenzo[b]furans in Water.
  119. Synthesis of 2-Substituted Indoles via Pd/C-Catalyzed Reaction in Water
  120. Palladium catalyzed reaction in aqueous DMF: synthesis of 3-alkynyl substituted flavones in the presence of prolinol
  121. Pd/C mediated synthesis of 2-substituted benzo[b]furans/nitrobenzo[b]furans in water
  122. Conformationally Restricted 3,4-Diarylfuranones (2,3a,4,5-Tetrahydronaphthofuranones) as Selective Cyclooxygenase-2 Inhibitors.
  123. An improved and practical synthesis of 5,5-dimethyl-3-(2-propoxy)-4-(4-methanesulfonylphenyl)-2-(5H)-furanone (DFP—a selective inhibitor of cyclooxygenase-2)
  124. Synthesis and Cyclooxygenase (COX-1/COX-2) Inhibiting Property of 3,4-Diarylfuranones.
  125. Palladium-Catalyzed Cleavage of O/N-Propargyl Protecting Groups in Aqueous Media under a Copper-Free Condition.
  126. Regioselective Aluminum Chloride Induced Heteroarylation of Pyrrolo[1,2-b]pyridazines: Its Scope and Application.
  127. Palladium-Catalyzed Cleavage of O/N-Propargyl Protecting Groups in Aqueous Media under a Copper-Free Condition 1
  128. Regioselective aluminium chloride induced heteroarylation of pyrrolo[1,2-b]pyridazines: its scope and application
  129. Synthesis of 3,4-Diarylsubstituted Maleic Anhydride/Maleimide via Unusual Oxidative Cyclization of Phenacyl Ester/Amide
  130. Palladium-catalysed heteroannulation with terminal alkynes: synthesis of phthalides 1
  131. Palladium-catalysed heteroannulation with acetylenic compounds: synthesis of benzofurans1