All Stories

  1. Quality by design tool evaluated green stability-indicating UPLC content determination method for the Olanzapine and Samidorphan dosage form
  2. Design, synthesis and in silico docking techniques of new 1,2,3-triazolylpyrrolidines bearing chalcone derivatives: Discovery of potent antitubercular agents
  3. Wang resin catalyzed sonochemical synthesis of 2-amino-3,5-dicarbonitrile-6-thio-pyridines as potential inhibitors of SIRT1
  4. Scalable and Cost-Effective Synthetic Process for the Preparation of l-3,4-Dihydroxyphenylalanine─Levodopa
  5. A quality‐by‐design evaluated liquid chromatography method development and validation for the separation and quantification of nitroxoline and its impurities
  6. Unique green chromatographic method for the qualitative and quantitative analysis of ketoconazole, its impurities and preservatives from ketoconazole cream formulation: Identification of degradants by Q-ToF LCMS and Robustness by Design of Experiments
  7. Investigating Betrixaban Maleate drug degradation profiles, isolation and characterization of unknown degradation products by mass-triggered preparative HPLC, HRMS, and NMR
  8. Quantification of Drospirenone- and Ethinyl Estradiol-Related Impurities in a Combined Pharmaceutical Dosage Form by a Chromatography Method With a QbD Robustness Study
  9. Internal stimuli-responsive nanocarriers for controlled anti-cancer drug release: a review
  10. Green metric tools for analytical methods assessment critical review, case studies and crucify
  11. Isolation, identification, structural elucidation, and toxicity prediction using (Q)-SAR models of two degradants: AQbD-driven LC method to determine the Roxadustat impurities
  12. Development of HPLC Method for Ixabepilone (Oncology Drug) in Bulk and Dosage Form: Quantification of Impurities and Forced Degradation Studies
  13. Antiproliferative Activity of New Pyrazole-4-sulfonamide Derivatives: Synthesis and Biological Evaluation
  14. Quality by design tool–evaluated stability‐indicating ultra‐performance liquid chromatography method for the determination of drugs (ritonavir and darunavir) used to treat the human immunodeficiency virus/acquired immunodeficiency syndrome
  15. Determination of Valbenazine related substances by liquid chromatography method complying with the current regulatory guidelines. Method robustness evaluation by Design of Experiments software
  16. Valbenazine isomers and enantiomer determination by chiral normal phase liquid chromatography
  17. Identification, isolation, and structural characterization of novel forced degradation products of Ertugliflozin using advanced analytical techniques
  18. Regulatory Perspective Reverse Engineering Analysis of the Mast Cell Stabilizer and the Histamine Receptor Antagonist (Olopatadine HCl): Instrumental and Classical Methods for Multiple Formulations
  19. QbD green analytical procedure for Novel study of a genotoxic and carcinogenic compound trace determination in physiological solution compatibility
  20. Design, synthesis, anticancer evaluation and molecular docking studies of 1,2,3-triazole incorporated 1,3,4-oxadiazole-Triazine derivatives
  21. Fast ion conduction and stable [Na-Si-P] glass-ceramic solid electrolyte mixed with hafnium and scandium ions: Application to Na-ion full cell
  22. Estimation of purity of antimicrobial lead compound sulfonamide‐anthranilate derivative methyl‐ester‐toluene‐sulfonamide using LC to develop a new drug application
  23. Development, stability‐indicating assessment, and evaluation of influential method conditions using a full factorial design for the determination of Nintedanib esylate‐related impurities
  24. A rapid synthesis of 5-substituted 7-amino-6-cyano-1,5-dihydro-1H-pyrano[2,3-d]pyrimidine-2,4(3H)-diones and their in silico / evaluation against SIRT1
  25. An effective and stability‐indicating method development and optimization utilizing the Box–Behnken design for the simultaneous determination of acetaminophen, caffeine, and aspirin in tablet formulation
  26. A validated stability‐indicating reversed‐phase liquid chromatography method for the quantification of Ixabepilone (Oncology drug) in the parenteral dosage form
  27. Enhanced photocatalytic performance of pebble stone like CuMoO4 photocatalyst for the degradation of organic pollutant
  28. Convenient synthesis, characterization and biological evaluation of novel 1-phenylcyclopropane carboxamide derivatives
  29. Studies on Ablative Performance of Silicone Low-Density Ablative Material
  30. Trace‐level determination of potential genotoxic impurities in quetiapine fumarate using LC–MS
  31. Recent Literature Review on Coumarin Hybrids as Potential Anticancer Agents
  32. A new synthetic approach to cyclic ureas through carbonylation using di-tert-butyl dicarbonate (boc anhydride) via one pot strategy
  33. Determination and quantification of related substances and degradation products in bictegravir by full factorial design evaluated HPLC and mass spectrometry
  34. An effective ultra‐performance liquid chromatography and derivatization method for the quantification of potential genotoxic impurity Hydrazine in Gliclazide and its formulation – Robustness study by the design of experiments
  35. A combined qualitative and quantitative method development and validation of vancomycin hydrochloride injection formulation by HPLC and UV involving quality by design
  36. Scalable Process of Methimazole
  37. Unique Quality by Design Approach for Developing HPLC and LC-MS Method for Estimation of Process and Degradation Impurities in Pibrentasvir, Antiviral Agent for Hepatitis C
  38. Stability-Indicating RP-HPLC Method Development and Validation for Eltrombopag Olamine in the Presence of Impurities and Degradation Products. Robustness by Design of Expert Software
  39. AQbD based green UPLC method to determine mycophenolate mofetil impurities and Identification of degradation products by QToF LCMS
  40. Molecular Hybrids of Pyazolo[3,4-b]pyridine and Triazole: Design, Synthesis and In Vitro Antibacterial Studies
  41. Suitability and performance of NaNi1-x(VO)xPO4 mixed polyanion glass and Glass-Ceramic cathodes for Na-ion battery
  42. Role of Natural Products in Developing Novel Anticancer Agents: A Perspective
  43. GCN decorated manganese oxide for photocatalytic degradation of methylene blue
  44. Wang resin catalyzed sonochemical synthesis of dihydropyrano[2,3-c]pyrazole derivatives and their interactions with SIRT1
  45. Green Chromatographic Method for Determination of Active Pharmaceutical Ingredient, Preservative, and Antioxidant in an Injectable Formulation: Robustness by Design Expert
  46. Identification, isolation, and structural characterization of novel forced degradation products of apixaban using advanced analytical techniques
  47. Molecular Hybrids of Pyrazolo[3,4-<em>b</em>]Pyridine and Triazole: Design, Synthesis and<em> in vitro</em> Antibacterial Studies
  48. Implementation of analytical quality by design and green chemistry principles to develop an ultra-high performance liquid chromatography method for the determination of Fluocinolone Acetonide impurities from its drug substance and topical oil formulations
  49. Improved and ‘Nitrosamines Free’ Process for the Preparation of an α4β2 Neuronal Nicotinic Acetylcholine Receptor Agonist-Varenicline Tartrate
  50. Development and validation of rapid ultra high performance liquid chromatography with tandem mass spectroscopic method for the quantification of N‐nitrosodimethyl amine and N‐nitrosodiethyl amine in sitagliptin and metformin hydrochloride immediate and...
  51. A quantitative nuclear magnetic resonance spectroscopic method development and validation to determine an absolute amount of levofloxacin hemihydrate in tablet dosage form
  52. Green Liquid Chromatography Method for the Determination of Related Substances Present in Olopatadine HCl Nasal Spray Formulation, Robustness by Design Expert
  53. Enhanced Long Cycle Life Stability and High Storage Reversible Capacity Retention of a Sodium Vanadate Zinc Glass–Ceramic Network
  54. Convalescent serum-derived exosomes: Attractive niche as COVID-19 diagnostic tool and vehicle for mRNA delivery
  55. Peptides-based therapeutics: Emerging potential therapeutic agents for COVID-19
  56. One-step synthesis of picolinohydrazides from fusaric acid: DFT, structural characterization and molecular inhibitory studies on metastatic tumor-derived exosomal and non-exosomal proteins
  57. Favipiravir (SARS‐CoV‐2) degradation impurities: Identification and route of degradation mechanism in the finished solid dosage form using LC/LC–MS method
  58. Wang-OSO3H catalyzed green synthesis of 2-arylamino-3-cyanopyridine derivatives under ultrasound: Their assessment as potential inhibitors of SIRT1
  59. Development and validation of liquid chromatography method for determination of Ibrutinib in finished dosage forms using quality by design approach
  60. Unique green chromatography method for the determination of serotonin receptor antagonist (Ondansetron hydrochloride) related substances in a liquid formulation, robustness by quality by design‐based design of experiments approach
  61. A Quality by Design and green LC technique for the determination of mast cell stabilizer and histamine receptor antagonist (Olopatadine HCl) in multiple formulations
  62. Lemon Juice: A Versatile Biocatalyst and Green Solvent in Organic Transformations
  63. A novel LC-MS/MS method for simultaneous estimation of acalabrutinib and its active metabolite acalabrutinib M27 in human plasma and application to a human pharmacokinetic study
  64. Discovery of 3-chlorobenzyl-linked 1,9-diazaspiro[5.5]undecane derivatives, a lead for dengue virus type 2 infection
  65. Mesoporous MOF composite for efficient removal of uranium, methyl orange, methylene blue, and Congo red dyes from aqueous solutions
  66. Sonochemical synthesis of 2-substituted nicotinic acid ethyl ester derivatives: Their in vitro and in silico evaluation against SIRT1
  67. Development of in-vitro release testing method for permethrin cream formulation using Franz Vertical Diffusion Cell apparatus by HPLC
  68. Na–Bi–Ge Glass Anode as a High‐Performance Network: Studies on Structure, High Rate Capability, and Long Cycle Stability
  69. A simple isocratic LC method for quantification of trace‐level inorganic degradation impurities (ferricyanide, ferrocyanide, nitrite, and nitrate) in sodium nitroprusside injection and robustness by quality using design approach
  70. A validated stability‐indicating reversed‐phase‐HPLC method for dipyridamole in the presence of degradation products and its process‐related impurities in pharmaceutical dosage forms
  71. Determination of progesterone (steroid drug) in the semi‐solid dosage form (vaginal gel) using a stability‐indicating method by RP‐HPLC/PDA detector
  72. Stability‐indicating reversed‐phase‐HPLC method development and validation for sacubitril/valsartan complex in the presence of impurities and degradation products: Robustness by quality‐by‐design approach
  73. Eco-friendly and green chromatographic method for the simultaneous determination of chlorocresol and betamethasone dipropionate in topical formulations using Box–Behnken design
  74. Amberlyst-15 catalysed sonochemical synthesis of 2-amino-4,6-disubstituted nicotinonitrile derivatives and their biological evaluation
  75. Highly sensitive liquid chromatography–tandem mass spectrometry assay for the determination of azathioprine in presence of mercaptopurine and its application to a human pharmacokinetic study
  76. Studies on Hollow Glass Microsphere Reinforced Silicone Matrix Composite for Use in Fast Curing Low Density Thermal Insulation Coating Applications
  77. Reverse-phase LC method development and validation for the quantification of acetazolamide and its specified and unspecified degradation products in hard gelatin capsule formulations
  78. Development and validation of a stability‐indicating UPLC method for the determination of olmesartan medoxomil, amlodipine and hydrochlorothiazide degradation impurities in their triple‐combination dosage form using factorial design of experiments
  79. A New Method for Preparation of Rilpivirine Intermediate
  80. An overview of vaccine development for COVID-19
  81. Fabrication and deployment of nanodisc ZnO@ZIF-8, ZnO@NA and ZnO@INA core–shell MOFs: enhanced NH3 and HCHO gas sensing
  82. Low‐level determination of 4‐chlorobutyl‐(S)‐[4‐chloro‐2‐(4‐cyclopropyl‐1,1,1‐trifluoro‐2‐hydroxy‐but‐3yn‐2‐yl)phenyl] carbamate (4‐CTHC) in efavirenz drug substance by LC–MS
  83. Development and Validation of RP-UPLC Method for 2,6-Dimethylaniline, Its Isomers, and Related Compounds Using Design of Experiments
  84. Recent Trends in the Synthesis and Mechanistic Implications of Phenanthridines
  85. A novel LC‐MS/MS method for simultaneous estimation of obeticholic acid, glyco‐obeticholic acid, tauro‐obeticholic acid in human plasma and its application to a pharmacokinetic study
  86. Influence of Titanium Content on Thermal, Mechanical and Corrosion Behaviour Anomalies of Nickel-Molybdenum-Silicate Bulk Metallic Glasses
  87. In vitro Dissolution Profile at Different Biological pH Conditions of Hydroxychloroquine Sulfate Tablets Is Available for the Treatment of COVID-19
  88. Novel reversed‐phase HPLC method for simultaneous determination of ethynodiol diacetate (EDA)/ethinyl estradiol (EE) in pharmaceutical dosage form
  89. Influence of Filler Content on Thermo-Physical Properties of Hollow Glass Microsphere- Silicone Matrix Composite
  90. Quantitative estimation of Fulvestrant injection 505(j) composition and impurities profile by capillary gas chromatography and HPLC-PDA techniques
  91. Development and validation of a RP-UPLC method for the determination of betamethasone dipropionate impurities in topical formulations using a multivariate central composite design
  92. Mixed Polyanion Na‐Mn‐V‐P Glass–Ceramic Cathode Network: Improved Electrochemical Performance and Stability
  93. A simple high‐performance liquid chromatography method development for Carbidopa and Levodopa impurities: Evaluation of risk assessment before method validation by Quality by Design approach
  94. An Improved Preparation of Azilsartan
  95. Investigation of High-Temperature Stability and Thermal Endurance of Silicone Potting Compound by Thermo-Gravimetric Analysis
  96. Stability Indicating LC Method Development for Hydroxychloroquine Sulfate Impurities as Available for Treatment of COVID-19 and Evaluation of Risk Assessment Prior to Method Validation by Quality by Design Approach
  97. Studies on thermal stability and life estimation of epoxy adhesive by thermogravimetric analysis for high-temperature applications
  98. Improvement in fast Na-ion conduction in Na3+xCrxTi2−x(PO4)3 glass–ceramic electrolyte material for Na-ion batteries
  99. Determination of lacosamide in human plasma by LC–MS/MS and its application to a human pharmacokinetic study
  100. Lemon Juice as a Biocatalyst Under Ultrasound Irradiation: Synthesis and Pharmacological Evaluation of 2-amino 1,3,4-thiadiazoles
  101. Human serum albumin interaction, in silico and anticancer evaluation of Pine-Gold nanoparticles
  102. TPGS-mediated one-pot synthesis, XRD structural analysis, antimicrobial evaluation and molecular docking of novel heterocycles as potential inhibitors of p53-MDM2 protein
  103. ZIF-8, Zn(NA) and Zn(INA) MOFs as chemical selective sensors of ammonia, formaldehyde and ethanol gases
  104. Lemon Juice Mediated Synthesis of 3-Substituted Quinazolin-4(3H)-Ones and their Pharmacological Evaluation
  105. Efficacy of biochar in removal of organic pesticide, Bentazone from watershed systems
  106. Synthesis of 2-Substituted 4-Arylidene-5(4H)-oxazolones as Potential Cytotoxic Agents in the Presence of Lemon Juice as a Biocatalyst
  107. 2,4‐Diphenyl‐1,2‐dihydroquinazoline Derivatives: Synthesis, Anticancer Activity and Docking Studies
  108. Stability‐indicating RP‐HPLC method development and validation for determination of nine impurities in apixaban tablet dosage forms. Robustness study by quality by design approach
  109. Simultaneous quantification of lidocaine and prilocaine in human plasma by LC-MS/MS and its application in a human pharmacokinetic study
  110. Development and validation of a generic RP‐HPLC PDA method for the simultaneous separation and quantification of active ingredients in cold and cough medicines
  111. Stability‐indicating HPLC method for simultaneous quantification of 14 impurities in excedrin tablet formulations and identification of new impurity by LC–MS in accelerated stability studies
  112. Na3+x[CrxTi2-x(PO4)3] glass-ceramic electrolyte: ionic conductivity and structural correlations for different heat treating temperatures and time schedules
  113. A novel UPLC-PDA isocratic method for the quantification fulvestrant in oil-based pre-filled syringe injection matrix formulations
  114. Investigation on the applicability of high Na-ion conducting Na3+x[ZrxSc2-x(PO4)3] glass-ceramic electrolyte for use in safer Na-ion batteries
  115. Unique Lewis and Bronsted acidic sites texture in the selective production of tetrahydropyran and oxepanefrom1,5-pentanediol and 1,6-hexanediol over sustainable red brick clay catalyst
  116. Simple one-pot green method for large-scale production of mesalamine, an anti-inflammatory agent
  117. Electrical properties and scaling studies of Na3+x ZrxSc2−x(PO4)3 glass ceramic electrolyte for use in Na-ion batteries
  118. Bioanalytical technique for determination of tasimelteon in human plasma by LC–MS/MS and its application to pharmacokinetic study in humans
  119. Determination of ospemifene in human plasma by LC‐MS/MS and its application to a human pharmacokinetic study
  120. Design and synthesis of novel 6-substituted quinazoline-2-thiols
  121. Facile redbrick clay as splendid catalyst for selective dehydration of alcohols
  122. Oxone Mediated Oxidation of 2-(aryl/alkyl thio) Quinazolines: A Green Approach
  123. Synthesis and Antibacterial/Antitubercular/Antioxidant Activities of Compounds Containing Fluoroquinolone Ring Linked to a 4-thiazolidinone Moiety
  124. Electrochemical performance of SnO–V2O5–SiO2 glass anode for Na-ion batteries
  125. Simultaneous estimation of silodosin and silodosin β-D-glucuronide in human plasma using LC-MS/MS for a pharmacokinetic study
  126. Electrical conductivity of lithium phosphate glass-ceramics precipitated with nanocrystalline BaTiO3
  127. arb catalyst
  128. Fluoroquinolone
  129. Microwave-promoted Synthesis of S-substituted Quinazoline Derivatives using 1,4-dihydroquinazoline-2-thiol
  130. Entacapone
  131. chan-lam
  132. Tandem
  133. li-ge-p
  134. linear frac
  135. Aminobenzazoles
  136. cross-coupling of quinazoline thiols
  137. Dithiocarbamate promoted synthesis of aminobenzazoles
  138. L-arginine catalysed knoevenagel condensation
  139. ChemInform Abstract: Dithiocarbamate‐ and DBU‐Promoted Amide Bond Formation under Microwave Condition.
  140. Dithiocarbamate and DBU-promoted amide bond formation under microwave condition
  141. ChemInform Abstract: Dithiocarbamate‐ and CuO‐Promoted One‐Pot Synthesis of 2‐(N‐Substituted)‐aminobenzimidazoles and Related Heterocycles.
  142. Dithiocarbamate and CuO promoted one-pot synthesis of 2-(N-substituted)-aminobenzimidazoles and related heterocycles