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  1. Relationship between the radical-scavenging activity of selected flavonols and thermodynamic parameters calculated by density functional theory

    Article • Free Radical Research, July 2020, Taylor & Francis

    Dr Ikuo Nakanishi

  2. A large kinetic isotope effect in the reaction of ascorbic acid with 2-phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl 3-oxide (PTIO˙) in aqueous buffer solutions

    Article • Chemical Communications, January 2020, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  3. Synthesis and radical-scavenging activity of C-methylated fisetin analogues

    Article • Bioorganic & Medicinal Chemistry, February 2019, Elsevier

    Dr Ikuo Nakanishi

  4. Effect of plateau carbon-ion beams

    Article • Organic & Biomolecular Chemistry, January 2018, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  5. Efficient protective activity of a planar catechin analogue against radiation-induced apoptosis in rat thymocytes

    Article • RSC Advances, January 2018, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  6. Enhanced radical scavenging activity of a procyanidin B3 analogue comprised of a dimer of planar catechin

    Article • Bioorganic & Medicinal Chemistry Letters, October 2017, Elsevier

    Dr Ikuo Nakanishi

  7. Synthesis and antioxidant activity of a procyanidin B3 analogue

    Article • Bioorganic & Medicinal Chemistry Letters, February 2017, Elsevier

    Dr Ikuo Nakanishi

  8. Synthesis of methylated quercetin analogues for enhancement of radical-scavenging activity

    Article • RSC Advances, January 2017, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  9. A facile and rapid access to resveratrol derivatives and their radioprotective activity

    Article • Bioorganic & Medicinal Chemistry Letters, August 2016, Elsevier

    Dr Ikuo Nakanishi

  10. Aluminium ion-promoted radical-scavenging reaction of methylated hydroquinone derivatives

    Article • Organic & Biomolecular Chemistry, January 2016, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  11. Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media

    Article • Chemical Communications, January 2015, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  12. Synthesis and radical-scavenging activity of a dimethyl catechin analogue

    Article • Bioorganic & Medicinal Chemistry Letters, June 2014, Elsevier

    Dr Ikuo Nakanishi

  13. Disproportionation of a 2,2-diphenyl-1-picrylhydrazyl radical as a model of reactive oxygen species catalysed by Lewis and/or Brønsted acids

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  14. Scavenging of reactive oxygen species induced by hyperthermia in biological fluid

    Article • Journal of Clinical Biochemistry and Nutrition, January 2014, The Society for Free Radical Research Japan

    Dr Ikuo Nakanishi

  15. High-Throughput Screening of Radioprotectors Using Rat Thymocytes

    Article • Analytical Chemistry, August 2013, American Chemical Society (ACS)

    Dr Ikuo Nakanishi

  16. Effects of ionic radius of redox-inactive bio-related metal ions on the radical-scavenging activity of flavonoids evaluated using photometric titration

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  17. Method for assessing X-ray-induced hydroxyl radical-scavenging activity of biological compounds/materials

    Article • Journal of Clinical Biochemistry and Nutrition, January 2013, The Society for Free Radical Research Japan

    Dr Ikuo Nakanishi

  18. Comparison of in vivo and in vitro antioxidative parameters for eleven food factors

    Article • RSC Advances, January 2013, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  19. Radical-Scavenging Reactions of Ascorbic Acid and Its Analogue in the Presence of a Redox-Inactive Metal Ion

    Article • Free Radical Biology and Medicine, November 2012, Elsevier

    Dr Ikuo Nakanishi

  20. Comparison of Blood-Brain-Barrier Permeable Nitroxyl Contrast Agents for Magnetic Resonance Brain Redox Imaging

    Article • Free Radical Biology and Medicine, November 2012, Elsevier

    Dr Ikuo Nakanishi

  21. Kinetics and Mechanism for the Scavenging Reaction of the 2,2-Diphenyl-1-picrylhydrazyl Radical by Synthetic Artepillin C Analogues

    Article • Bulletin of the Chemical Society of Japan, August 2012, The Chemical Society of Japan

    Dr Ikuo Nakanishi

  22. Chlorine atom substitution influences radical scavenging activity of 6-chromanol

    Article • Bioorganic & Medicinal Chemistry, July 2012, Elsevier

    Dr Ikuo Nakanishi

  23. Roles of mitochondria-generated reactive oxygen species on X-ray-induced apoptosis in a human hepatocellular carcinoma cell line, HLE

    Article • Free Radical Research, June 2012, Taylor & Francis

    Dr Ikuo Nakanishi

  24. ChemInform Abstract: Synthesis and Enhanced Radical Scavenging Activity of a Conformationally Constrained Epigallocatechin Analogue (III).

    Article • ChemInform, April 2012, Wiley

    Dr Ikuo Nakanishi

  25. The high stability of intermediate radicals enhances the radical-scavenging activity of aminochromanols

    Article • RSC Advances, January 2012, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  26. Efficient Method for Hydroxyl Radical Scavenging Activity of Antioxidants

    Article • Free Radical Biology and Medicine, November 2011, Elsevier

    Dr Ikuo Nakanishi

  27. Radica-Scavenging Activity of 6-Chromanol Derivatives with Various Substituents

    Article • Free Radical Biology and Medicine, November 2011, Elsevier

    Dr Ikuo Nakanishi

  28. Synthesis and Enhanced Radical Scavenging Activity of a Conformationally Constrained Epigallocatechin Analogue

    Article • Chemistry Letters, January 2011, Chemical Society of Japan

    Dr Ikuo Nakanishi

  29. Temperature-dependent free radical reaction in water

    Article • Journal of Clinical Biochemistry and Nutrition, January 2011, The Society for Free Radical Research Japan

    Dr Ikuo Nakanishi

  30. Synthesis of Conformationally Constrained Epigallocatechin Analogue as a Promising Antioxidant

    Article • Free Radical Biology and Medicine, January 2010, Elsevier

    Dr Ikuo Nakanishi

  31. Electron Transfer from Stable Superoxide Complex to Electron Acceptors as Benzoquinone Derivatives

    Article • Free Radical Biology and Medicine, January 2010, Elsevier

    Dr Ikuo Nakanishi

  32. Reaction of Nitroxyl Radicals and GSH; pH Dependence

    Article • Free Radical Biology and Medicine, January 2010, Elsevier

    Dr Ikuo Nakanishi

  33. Potent 2,2-Diphenyl-1-picrylhydrazyl Radical-Scavenging Activity of Novel Antioxidants, Double-Stranded Tyrosine Residues Conjugating Pyrocatechol

    Article • Chemical and Pharmaceutical Bulletin, January 2010, Pharmaceutical Society of Japan

    Dr Ikuo Nakanishi

  34. Electron-Transfer Properties of the Phenolate Anion Derived from a Vitamin E Model in the Presence of a Strong Base in an Aprotic Medium

    Article • Free Radical Biology and Medicine, January 2010, Elsevier

    Dr Ikuo Nakanishi

  35. Novel ninhydrin adduct of catechin with potent antioxidative activity

    Article • Tetrahedron Letters, December 2009, Elsevier

    Dr Ikuo Nakanishi

  36. Intracellular and Extracellular Redox Environments Surrounding Redox-Sensitive Contrast Agents under Oxidative Atmosphere

    Article • Biological and Pharmaceutical Bulletin, January 2009, Pharmaceutical Society of Japan

    Dr Ikuo Nakanishi

  37. Intramolecular base-accelerated radical-scavenging reaction of a planar catechin derivative bearing a lysine moiety

    Article • Chemical Communications, January 2009, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  38. Effect of Methyl Substitution on the Antioxidative Property and Genotoxicity of Resveratrol

    Article • Chemical Research in Toxicology, February 2008, American Chemical Society (ACS)

    Dr Ikuo Nakanishi

  39. Enhanced radical-scavenging activity of naturally-oriented artepillin C derivatives

    Article • Chemical Communications, January 2008, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  40. Involvement of Electron Transfer in the Radical-scavenging Reaction of Resveratrol

    Article • Chemistry Letters, October 2007, The Chemical Society of Japan

    Dr Ikuo Nakanishi

  41. Effect of Solvent Polarity on the One-electron Oxidation of Cyclic Nitroxyl Radicals

    Article • Chemistry Letters, July 2007, The Chemical Society of Japan

    Dr Ikuo Nakanishi

  42. A Long-lived o-Semiquinone Radical Anion is Formed from N- -alanyl-5-S-glutathionyl-3,4-dihydroxyphenylalanine (5-S-GAD), an Insect-derived Antibacterial Substance

    Article • The Journal of Biochemistry, April 2007, Oxford University Press (OUP)

    Dr Ikuo Nakanishi

  43. Scandium Ion-accelerated Scavenging Reaction of Cumylperoxyl Radical by a Cyclic Nitroxyl Radical via Electron Transfer

    Article • Chemistry Letters, March 2007, The Chemical Society of Japan

    Dr Ikuo Nakanishi

  44. Nitroxyl radicals: electrochemical redox behaviour and structure–activity relationships

    Article • Organic & Biomolecular Chemistry, January 2007, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  45. Planar Catechin Analogues with Alkyl Side Chains:  A Potent Antioxidant and an α-Glucosidase Inhibitor

    Article • Journal of the American Chemical Society, May 2006, American Chemical Society (ACS)

    Dr Ikuo Nakanishi

  46. Comparison of stable nitroxide, 3-substituted 2,2,5,5-tetramethylpyrrolidine-N-oxyls, with respect to protection from radiation, prevention of DNA damage, and distribution in mice

    Article • Free Radical Biology and Medicine, April 2006, Elsevier

    Dr Ikuo Nakanishi

  47. Structural basis for DNA-cleaving activity of resveratrol in the presence of Cu(II)

    Article • Bioorganic & Medicinal Chemistry, March 2006, Elsevier

    Dr Ikuo Nakanishi

  48. Reaction ofpara-hydroxybenzoic acid esters with singlet oxygen in the presence of glutathione produces glutathione conjugates of hydroquinone, potent inducers of oxidative stress

    Article • Free Radical Research, January 2006, Taylor & Francis

    Dr Ikuo Nakanishi

  49. Electron-transfer mechanism in radical-scavenging reactions by a vitamin E model in a protic medium

    Article • Organic & Biomolecular Chemistry, January 2005, Royal Society of Chemistry

    Shinobu Itoh, Dr Ikuo Nakanishi

  50. Hydroxyl radical generation via photoreduction of a simple pyridine N-oxide by an NADH analogue

    Article • Organic & Biomolecular Chemistry, January 2005, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  51. EPR Study on Stable Magnesium Complexes of the Phenoxyl Radicals Derived from a Vitamin E Model and Its Deuterated Derivatives

    Article • Bulletin of the Chemical Society of Japan, January 2004, Chemical Society of Japan

    Shinobu Itoh, Dr Ikuo Nakanishi

  52. A Planar Catechin Analogue Having a More Negative Oxidation Potential than (+)-Catechin as an Electron Transfer Antioxidant against a Peroxyl Radical

    Article • Chemical Research in Toxicology, January 2004, American Chemical Society (ACS)

    Dr Ikuo Nakanishi

  53. Efficient radical scavenging ability of artepillin C, a major component of Brazilian propolis, and the mechanism

    Article • Organic & Biomolecular Chemistry, April 2003, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  54. Kinetic study of the electron-transfer oxidation of the phenolate anion of a vitamin E model by molecular oxygen generating superoxide anion in an aprotic mediumElectronic supplementary information (ESI) available: the cyclic voltammogram of 1? and the...

    Article • Organic & Biomolecular Chemistry, January 2003, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  55. A Planar Catechin Analogue as a Promising Antioxidant with Reduced Prooxidant Activity

    Article • Chemical Research in Toxicology, January 2003, American Chemical Society (ACS)

    Dr Ikuo Nakanishi

  56. Effects of Metal Ions Distinguishing between One-Step Hydrogen- and Electron-Transfer Mechanisms for the Radical-Scavenging Reaction of (+)-Catechin

    Article • The Journal of Physical Chemistry A, November 2002, American Chemical Society (ACS)

    Dr Ikuo Nakanishi

  57. Direct detection of superoxide anion generated in C60-photosensitized oxidation of NADH and an analogue by molecular oxygen

    Article • Journal of the Chemical Society Perkin Transactions 2, September 2002, Royal Society of Chemistry

    Dr Ikuo Nakanishi

  58. Effects of magnesium ion on kinetic stability and spin distribution of phenoxyl radical derived from a vitamin E analogue: mechanistic insight into antioxidative hydrogen-transfer reaction of vitamin EElectronic supplementary information available: cal...

    Article • Journal of the Chemical Society Perkin Transactions 2, July 2002, Royal Society of Chemistry

    Shinobu Itoh, Dr Ikuo Nakanishi

  59. Enhanced Radical-Scavenging Activity of a Planar Catechin Analogue

    Article • Journal of the American Chemical Society, May 2002, American Chemical Society (ACS)

    Dr Ikuo Nakanishi

  60. DNA Cleavage via Superoxide Anion Formed in Photoinduced Electron Transfer from NADH to γ-Cyclodextrin-Bicapped C 60 in an Oxygen-Saturated Aqueous Solution

    Article • The Journal of Physical Chemistry, March 2002, American Chemical Society (ACS)

    Dr Ikuo Nakanishi

  61. ChemInform Abstract: Hydroxylation of Nitrated Naphthalenes with KO2/Crown Ether.

    Article • ChemInform, March 2001, Wiley

    Dr Ikuo Nakanishi

  62. ChemInform Abstract: Reactive Species Responsible for Biological Actions of Photoexcited Fullerenes

    Article • ChemInform, February 2001, Wiley

    Dr Ikuo Nakanishi

  63. Base Control of Electron-Transfer Reactions of Manganese(III) Porphyrins

    Article • European Journal of Inorganic Chemistry, July 2000, Wiley

    Dr Ikuo Nakanishi

  64. Hydroxylation of Nitrated Naphthalenes with KO2/Crown Ether.

    Article • Chemical and Pharmaceutical Bulletin, January 2000, Pharmaceutical Society of Japan

    Dr Ikuo Nakanishi

  65. Multielectron Oxidation of Anthracenes with a One-Electron Oxidant via Water-Accelerated Electron-Transfer Disproportionation of the Radical Cations as the Rate-Determining Step

    Article • The Journal of Physical Chemistry A, December 1999, American Chemical Society (ACS)

    Dr Ikuo Nakanishi

  66. Migration Reactivities of σ-Bonded Ligands of Organoiron and Organocobalt Porphyrins Depending on Different High Oxidation States

    Article • Inorganic Chemistry, November 1999, American Chemical Society (ACS)

    Dr Ikuo Nakanishi

  67. Electron-Transfer Properties of Active Aldehydes of Thiamin Coenzyme Models, and Mechanism of Formation of the Reactive Intermediates

    Article • Chemistry - A European Journal, October 1999, Wiley

    Dr Ikuo Nakanishi

  68. Synthesis and Electrochemical Studies of a Series of Fluorinated Dodecaphenylporphyrins

    Article • Inorganic Chemistry, May 1999, American Chemical Society (ACS)

    Dr Ikuo Nakanishi

  69. Decreased Electron Transfer Rates of Manganese Porphyrins with Conformational Distortion of the Macrocycle

    Article • Angewandte Chemie International Edition, April 1999, Wiley

    Dr Ikuo Nakanishi

  70. Electron-Transfer Properties of C60 and tert-Butyl-C60 Radical

    Article • Journal of the American Chemical Society, March 1999, American Chemical Society (ACS)

    Dr Ikuo Nakanishi

  71. Electron-Transfer Kinetics for Generation of Organoiron(IV) Porphyrins and the Iron(IV) Porphyrin π Radical Cations

    Article • Journal of the American Chemical Society, February 1999, American Chemical Society (ACS)

    Dr Ikuo Nakanishi

  72. Formation of Radical Anions in the Reaction of p-Benzoquinone and C60 with Alkoxide Ions

    Article • Journal of the American Chemical Society, June 1998, American Chemical Society (ACS)

    Shinobu Itoh, Dr Ikuo Nakanishi

  73. Direct Observation of Radical Intermediates While Investigating the Redox Behavior of Thiamin Coenzyme Models

    Article • Angewandte Chemie International Edition, April 1998, Wiley

    Dr Ikuo Nakanishi

  74. Direkte Beobachtung radikalischer Zwischenstufen bei Untersuchungen zum Redoxverhalten von Modellen des Coenzyms Thiamin

    Article • Angewandte Chemie, April 1998, Wiley

    Dr Ikuo Nakanishi

  75. Redox Behavior of Active Aldehydes Derived from Thiamin Coenzyme Analogs.

    Article • Chemistry Letters, January 1997, Chemical Society of Japan

    Shinobu Itoh, Dr Ikuo Nakanishi

  76. Electron transfer properties of active aldehydes derived from thiamin coenzyme analogues

    Article • Chemical Communications, January 1997, Royal Society of Chemistry

    Shinobu Itoh, Dr Ikuo Nakanishi