All Stories

  1. Why Leave a Job Half Done? Recent Progress in Enzymatic Deracemizations

    Article • Current Green Chemistry, April 2015, Bentham Science Publishers

    Dr Ivan Lavandera

  2. (Chemo)enzymatic cascades—Nature's synthetic strategy transferred to the laboratory

    Article • Journal of Molecular Catalysis B Enzymatic, April 2015, Elsevier

    Dr Ivan Lavandera, Dr Eduardo García-Junceda

  3. Deracemisation of profenol core by combining laccase/TEMPO-mediated oxidation and alcohol dehydrogenase-catalysed dynamic kinetic resolution

    Article • Catalysis Science & Technology, January 2015, Royal Society of Chemistry

    Dr Ivan Lavandera

  4. ChemInform Abstract: Biocatalysis Applied to the Synthesis of Valuable Triazole-Containing Derivatives

    Article • ChemInform, January 2015, Wiley

    Dr Ivan Lavandera

  5. ChemInform Abstract: Laccase/2,2,6,6-Tetramethylpiperidinoxyl Radical (TEMPO): An Efficient Catalytic System for Selective Oxidations of Primary Hydroxy and Amino Groups in Aqueous and Biphasic Media.

    Article • ChemInform, December 2014, Wiley

    Dr Ivan Lavandera

  6. Inside Cover Picture: Laccase/2,2,6,6-Tetramethylpiperidinoxyl Radical (TEMPO): An Efficient Catalytic System for Selective Oxidations of Primary Hydroxy and Amino Groups in Aqueous and Biphasic Media (Adv. Synth. Catal. 10/2014)

    Article • Advanced Synthesis & Catalysis, June 2014, Wiley

    Dr Ivan Lavandera

  7. Laccase/2,2,6,6-Tetramethylpiperidinoxyl Radical (TEMPO): An Efficient Catalytic System for Selective Oxidations of Primary Hydroxy and Amino Groups in Aqueous and Biphasic Media

    Article • Advanced Synthesis & Catalysis, June 2014, Wiley

    Dr Ivan Lavandera

  8. Transaminases Applied to the Synthesis of High Added-Value Enantiopure Amines

    Article • Organic Process Research & Development, June 2014, American Chemical Society (ACS)

    Dr Ivan Lavandera

  9. ChemInform Abstract: Highly Enantioselective Synthesis of α-Azido-β-hydroxy Methyl Ketones Catalyzed by a Cooperative Proline-Guanidinium Salt System.

    Article • ChemInform, June 2014, Wiley

    Dr Ivan Lavandera

  10. ChemInform Abstract: Escherichia coli/ADH-A: An All-Inclusive Catalyst for the Selective Biooxidation and Deracemisation of Secondary Alcohols.

    Article • ChemInform, April 2014, Wiley

    Dr Ivan Lavandera

  11. Asymmetric chemoenzymatic synthesis of N-acetyl-α-amino esters based on lipase-catalyzed kinetic resolutions through interesterification reactions

    Article • Tetrahedron, April 2014, Elsevier

    Dr Ivan Lavandera

  12. ChemInform Abstract: Expanding Dynamic Kinetic Protocols: Transaminase-Catalyzed Synthesis of α-Substituted β-Amino Ester Derivatives.

    Article • ChemInform, March 2014, Wiley

    Dr Ivan Lavandera

  13. Short-chain dehydrogenase from Sphingobium yanoikuyae in complex with NADPH

    Article • March 2014, Protein Data Bank, Rutgers University

    Dr Ivan Lavandera

  14. Expanding the Scope of Alcohol Dehydrogenases towards Bulkier Substrates: Stereo- and Enantiopreference for α,α-Dihalogenated Ketones

    Article • ChemCatChem, February 2014, Wiley

    Dr Ivan Lavandera, Santiago Garcia-Granda

  15. Stereodivergent Preparation of Valuable γ- or δ-Hydroxy Esters and Lactones through One-Pot Cascade or Tandem Chemoenzymatic Protocols

    Article • ACS Catalysis, February 2014, American Chemical Society (ACS)

    Dr Ivan Lavandera

  16. Steric vs. electronic effects in the Lactobacillus brevis ADH-catalyzed bioreduction of ketones

    Article • Organic & Biomolecular Chemistry, January 2014, Royal Society of Chemistry

    Dr Ivan Lavandera

  17. Highly enantioselective synthesis of α-azido-β-hydroxy methyl ketones catalyzed by a cooperative proline–guanidinium salt system

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    Dr Ivan Lavandera

  18. Laccase/TEMPO-mediated system for the thermodynamically disfavored oxidation of 2,2-dihalo-1-phenylethanol derivatives

    Article • Green Chemistry, January 2014, Royal Society of Chemistry

    Dr Ivan Lavandera

  19. Regioselective Preparation of Thiamphenicol Esters Through Lipase-Catalyzed Processes

    Article • Journal of the Brazilian Chemical Society, January 2014, GN1 Genesis Network

    Dr Ivan Lavandera

  20. Imidazolium-Based Ionic Liquids as Non-conventional Media for Alcohol Dehydrogenase-Catalysed Reactions

    Article • Topics in Catalysis, November 2013, Springer Science + Business Media

    Dr Ivan Lavandera

  21. Structures of Alcohol Dehydrogenases from Ralstonia and Sphingobium spp. Reveal the Molecular Basis for Their Recognition of ‘Bulky–Bulky’ Ketones

    Article • Topics in Catalysis, November 2013, Springer Science + Business Media

    Dr Ivan Lavandera

  22. ChemInform Abstract: Synthesis of Enantiopure Fluorohydrins Using Alcohol Dehydrogenases at High Substrate Concentrations.

    Article • ChemInform, November 2013, Wiley

    Dr Ivan Lavandera

  23. Escherichia coli/ADH-A: An All-Inclusive Catalyst for the Selective Biooxidation and Deracemisation of Secondary Alcohols

    Article • ChemCatChem, September 2013, Wiley

    Dr Ivan Lavandera

  24. Biocatalyzed synthesis of both enantiopure fluoromisonidazole antipodes

    Article • Tetrahedron Letters, September 2013, Elsevier

    Dr Ivan Lavandera

  25. Synthetic Strategies Based on CO Bioreductions for the Preparation of Biologically Active Molecules

    Article • August 2013, Wiley

    Dr Ivan Lavandera

  26. Synthesis of Enantiopure Fluorohydrins Using Alcohol Dehydrogenases at High Substrate Concentrations

    Article • The Journal of Organic Chemistry, July 2013, American Chemical Society (ACS)

    Dr Ivan Lavandera

  27. ChemInform Abstract: Coupling Biocatalysis and Click Chemistry: One-Pot Two-Step Convergent Synthesis of Enantioenriched 1,2,3-Triazole-Derived Diols.

    Article • ChemInform, June 2013, Wiley

    Dr Ivan Lavandera

  28. ChemInform Abstract: From Diols to Lactones under Aerobic Conditions Using a Laccase/TEMPO Catalytic System in Aqueous Medium.

    Article • ChemInform, April 2013, Wiley

    Dr Ivan Lavandera

  29. Mimicking Nature: Synthetic Nicotinamide Cofactors for C═C Bioreduction Using Enoate Reductases

    Article • Organic Letters, January 2013, American Chemical Society (ACS)

    Dr Ivan Lavandera

  30. Coupling biocatalysis and click chemistry: one-pot two-step convergent synthesis of enantioenriched 1,2,3-triazole-derived diols

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Dr Ivan Lavandera

  31. Expanding dynamic kinetic protocols: transaminase-catalyzed synthesis of α-substituted β-amino ester derivatives

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Dr Ivan Lavandera

  32. From Diols to Lactones under Aerobic Conditions using a Laccase/TEMPO Catalytic System in Aqueous Medium

    Article • Advanced Synthesis & Catalysis, December 2012, Wiley

    Dr Ivan Lavandera

  33. ChemInform Abstract: Chemoenzymatic Preparation of Optically Active 3-(1H-Imidazol-1-yl)cyclohexanol-based Ionic Liquids: Application in Organocatalysis and Toxicity Studies.

    Article • ChemInform, November 2012, Wiley

    Dr Ivan Lavandera

  34. Recent Advances in Cofactor Regeneration Systems Applied to Biocatalyzed Oxidative Processes

    Article • Current Organic Chemistry, November 2012, Bentham Science Publishers

    Dr Ivan Lavandera

  35. ChemInform Abstract: Expanding the Regioselective Enzymatic Repertoire: Oxidative Monocleavage of Dialkenes Catalyzed by Trametes hirsuta.

    Article • ChemInform, July 2012, Wiley

    Dr Ivan Lavandera

  36. Access to Enantiopure α-Alkyl-β-hydroxy Esters through Dynamic Kinetic Resolutions Employing Purified/Overexpressed Alcohol Dehydrogenases

    Article • Advanced Synthesis & Catalysis, May 2012, Wiley

    Dr Ivan Lavandera

  37. ChemInform Abstract: Recent Advances in Biocatalysis Applied to Organic Synthesis

    Article • ChemInform, April 2012, Wiley

    Dr Ivan Lavandera

  38. Concepts in Biocatalysis

    Article • April 2012, Wiley

    Dr Ivan Lavandera

  39. Immobilized redox enzymatic catalysts: Baeyer–Villiger monooxygenases supported on polyphosphazenes

    Article • Journal of Molecular Catalysis B Enzymatic, February 2012, Elsevier

    Dr Ivan Lavandera

  40. Development of a routine method for the simultaneous confirmation and determination of clenbuterol in urine by minimal labeling isotope pattern deconvolution and GC-EI-MS

    Article • Analytical and Bioanalytical Chemistry, January 2012, Springer Science + Business Media

    Dr Ivan Lavandera

  41. Expanding the regioselective enzymatic repertoire: oxidative mono-cleavage of dialkenes catalyzed by Trametes hirsuta

    Article • Chemical Communications, January 2012, Royal Society of Chemistry

    Dr Ivan Lavandera

  42. Chemoenzymatic preparation of optically active 3-(1H-imidazol-1-yl)cyclohexanol-based ionic liquids: application in organocatalysis and toxicity studies

    Article • RSC Advances, January 2012, Royal Society of Chemistry

    Dr Ivan Lavandera, Santiago Garcia-Granda

  43. A straightforward route to obtain 13C1-labeled clenbuterol

    Article • Tetrahedron, August 2011, Elsevier

    Dr Ivan Lavandera

  44. Dynamic Kinetic Resolution of α-Substituted β-Ketoesters Catalyzed by Baeyer-Villiger Monooxygenases: Access to Enantiopure α-Hydroxy Esters

    Article • Angewandte Chemie International Edition, July 2011, Wiley

    Dr Ivan Lavandera

  45. Dynamic Kinetic Resolution of α-Substituted β-Ketoesters Catalyzed by Baeyer-Villiger Monooxygenases: Access to Enantiopure α-Hydroxy Esters

    Article • Angewandte Chemie, July 2011, Wiley

    Dr Ivan Lavandera

  46. Recent Advances in Biocatalysis Applied to Organic Synthesis

    Article • July 2011, Wiley

    Dr Ivan Lavandera

  47. Biocatalytic Concurrent Processes

    Article • April 2011, Wiley

    Dr Ivan Lavandera

  48. Enzymatic regioselective production of chloramphenicol esters

    Article • Tetrahedron, April 2011, Elsevier

    Dr Ivan Lavandera

  49. ChemInform Abstract: Reduction Processes Biocatalyzed by Vigna unguiculata.

    Article • ChemInform, September 2010, Wiley

    Dr Ivan Lavandera

  50. Ketone-Alcohol Hydrogen-Transfer Equilibria: Is the Biooxidation of Halohydrins Blocked?

    Article • Chemistry - A European Journal, August 2010, Wiley

    Dr Ivan Lavandera

  51. Testing of microorganisms for ω-transaminase activity

    Article • Tetrahedron Asymmetry, August 2010, Elsevier

    Dr Ivan Lavandera

  52. Chemo- and Stereodivergent Preparation of Terminal Epoxides and Bromohydrins through One-Pot Biocatalysed Reactions: Access to Enantiopure Five- and Six-Membered N-Heterocycles

    Article • Advanced Synthesis & Catalysis, June 2010, Wiley

    Dr Ivan Lavandera

  53. Oxidoreductases Working Together: Concurrent Obtaining of Valuable Derivatives by Employing the PIKAT Method

    Article • ChemCatChem, June 2010, Wiley

    Dr Ivan Lavandera

  54. Polyphosphazenes as Tunable and Recyclable Supports To Immobilize Alcohol Dehydrogenases and Lipases: Synthesis, Catalytic Activity, and Recycling Efficiency

    Article • Biomacromolecules, May 2010, American Chemical Society (ACS)

    Dr Ivan Lavandera

  55. Chemo-promiscuity of alcohol dehydrogenases: reduction of phenylacetaldoxime to the alcohol

    Article • Tetrahedron, May 2010, Elsevier

    Dr Ivan Lavandera

  56. Reduction processes biocatalyzed by Vigna unguiculata

    Article • Tetrahedron Asymmetry, March 2010, Elsevier

    Dr Ivan Lavandera

  57. Biocatalysed concurrent production of enantioenriched compounds through parallel interconnected kinetic asymmetric transformations

    Article • Organic & Biomolecular Chemistry, January 2010, Royal Society of Chemistry

    Dr Ivan Lavandera

  58. ChemInform Abstract: Simple and Quick Preparation of α-Thiocyanate Ketones in Hydroalcoholic Media. Access to 5-Aryl-2-imino-1,3-oxathiolanes.

    Article • ChemInform, August 2009, Wiley

    Dr Ivan Lavandera

  59. Biocatalytic oxidation of benzyl alcohol to benzaldehyde via hydrogen transfer

    Article • Tetrahedron, August 2009, Elsevier

    Dr Ivan Lavandera

  60. Promiscuous Substrate Binding Explains the Enzymatic Stereo- and Regiocontrolled Synthesis of Enantiopure Hydroxy Ketones and Diols

    Article • Advanced Synthesis & Catalysis, August 2009, Wiley

    Dr Ivan Lavandera

  61. Biocatalytic Cascade for the Synthesis of Enantiopure β-Azidoalcohols and β-Hydroxynitriles

    Article • European Journal of Organic Chemistry, May 2009, Wiley

    Dr Ivan Lavandera

  62. ChemInform Abstract: Asymmetric anti-Prelog Reduction of Ketones Catalyzed by Paracoccus pantotrophus and Comamonas sp. Cells via Hydrogen Transfer.

    Article • ChemInform, March 2009, Wiley

    Dr Ivan Lavandera

  63. Shifting the equilibrium of a biocatalytic cascade synthesis to enantiopure epoxides using anion exchangers

    Article • Tetrahedron Asymmetry, March 2009, Elsevier

    Dr Ivan Lavandera

  64. Tandem Concurrent Processes: One-Pot Single-Catalyst Biohydrogen Transfer for the Simultaneous Preparation of Enantiopure Secondary Alcohols

    Article • The Journal of Organic Chemistry, February 2009, American Chemical Society (ACS)

    Dr Ivan Lavandera

  65. Simple and quick preparation of α-thiocyanate ketones in hydroalcoholic media. Access to 5-aryl-2-imino-1,3-oxathiolanes

    Article • Green Chemistry, January 2009, Royal Society of Chemistry

    Dr Ivan Lavandera

  66. ChemInform Abstract: Stereoselective Bioreduction of Bulky-Bulky Ketones by a Novel ADH from Ralstonia sp.

    Article • ChemInform, December 2008, Wiley

    Dr Ivan Lavandera

  67. Asymmetric Synthesis of Optically Pure Pharmacologically Relevant Amines Employing ω-Transaminases

    Article • Advanced Synthesis & Catalysis, November 2008, Wiley

    Dr Ivan Lavandera

  68. Stereoselective anti-Prelog reduction of ketones by whole cells of Comamonas testosteroni in a ‘substrate-coupled’ approach

    Article • Journal of Molecular Catalysis B Enzymatic, November 2008, Elsevier

    Dr Ivan Lavandera

  69. Formal Asymmetric Biocatalytic Reductive Amination

    Article • Angewandte Chemie, October 2008, Wiley

    Dr Ivan Lavandera

  70. Formal Asymmetric Biocatalytic Reductive Amination

    Article • Angewandte Chemie International Edition, October 2008, Wiley

    Dr Ivan Lavandera

  71. Asymmetric anti-Prelog reduction of ketones catalysed by Paracoccus pantotrophus and Comamonas sp. cells via hydrogen transfer

    Article • Tetrahedron Asymmetry, August 2008, Elsevier

    Dr Ivan Lavandera

  72. Stereoselective Bioreduction of Bulky-Bulky Ketones by a Novel ADH from Ralstonia sp.

    Article • The Journal of Organic Chemistry, August 2008, American Chemical Society (ACS)

    Dr Ivan Lavandera

  73. One-Way Biohydrogen Transfer for Oxidation of sec -Alcohols

    Article • Organic Letters, June 2008, American Chemical Society (ACS)

    Dr Ivan Lavandera

  74. An Exceptionally DMSO-Tolerant Alcohol Dehydrogenase for the Stereoselective Reduction of Ketones

    Article • ChemSusChem, May 2008, Wiley

    Dr Ivan Lavandera

  75. Stereocomplementary Asymmetric Reduction of Bulky–Bulky Ketones by Biocatalytic Hydrogen Transfer

    Article • European Journal of Organic Chemistry, May 2008, Wiley

    Dr Ivan Lavandera

  76. Asymmetric biocatalytic reduction of ketones using hydroxy-functionalised water-miscible ionic liquids as solvents

    Article • Tetrahedron Asymmetry, October 2007, Elsevier

    Dr Ivan Lavandera

  77. Stereo-Complementary Two-Step Cascades Using a Two-Enzyme System Leading to Enantiopure Epoxides

    Article • Advanced Synthesis & Catalysis, June 2007, Wiley

    Dr Ivan Lavandera

  78. Novel and Efficient Chemoenzymatic Synthesis ofD-Glucose 6-Phosphate and Molecular Modeling Studies on the Selective Biocatalysis

    Article • European Journal of Organic Chemistry, June 2007, Wiley

    Dr Ivan Lavandera, Prof. Dr. Miguel Ferrero

  79. Enzymatic Reduction of Ketones in “Micro-aqueous” Media Catalyzed by ADH-A from Rhodococcus ruber

    Article • Organic Letters, May 2007, American Chemical Society (ACS)

    Dr Ivan Lavandera

  80. From a Racemate to a Single Enantiomer: Deracemization by Stereoinversion

    Article • ChemInform, January 2007, Wiley

    Dr Ivan Lavandera

  81. From a Racemate to a Single Enantiomer: Deracemization by Stereoinversion

    Article • Advanced Synthesis & Catalysis, September 2006, Wiley

    Dr Ivan Lavandera

  82. Biocatalytic Deuterium- and Hydrogen-Transfer using Over-Expressed ADH-‘A’

    Article • Synfacts, June 2006, Thieme Publishing Group

    Dr Ivan Lavandera

  83. Redesigning the mechanism of the lipase-catalysed aminolysis of esters

    Article • Tetrahedron Asymmetry, April 2006, Elsevier

    Dr Ivan Lavandera

  84. Biocatalytic preparation of enantioenriched 3,4-dihydroxypiperidines and theoretical study of Candida antarctica lipase B enantioselectivity

    Article • Tetrahedron, April 2006, Elsevier

    Dr Ivan Lavandera

  85. Remote Interactions Explain the Unusual Regioselectivity of Lipase from Pseudomonas cepacia toward the Secondary Hydroxyl of 2′-Deoxynucleosides

    Article • ChemBioChem, February 2006, Wiley

    Dr Ivan Lavandera, Prof. Dr. Miguel Ferrero

  86. Biocatalytic deuterium- and hydrogen-transfer using over-expressed ADH-‘A’: enhanced stereoselectivity and2H-labeled chiral alcohols

    Article • Chemical Communications, January 2006, Royal Society of Chemistry

    Dr Ivan Lavandera

  87. Novel and efficient regioselective enzymatic approach to 3′-, 5′- and 3′,5′-di-O-crotonyl 2′-deoxynucleoside derivatives

    Article • Tetrahedron Letters, August 2005, Elsevier

    Dr Ivan Lavandera, Prof. Dr. Miguel Ferrero

  88. An Inverse Substrate Orientation for the Regioselective Acylation of 3′,5′-Diaminonucleosides Catalyzed by Candida antarctica lipase B?

    Article • ChemBioChem, June 2005, Wiley

    Dr Ivan Lavandera, Prof. Dr. Miguel Ferrero

  89. Enzymatic Regioselective Levulinylation of 2′‐Deoxyribonucleosides and 2′‐ O ‐Methylribonucleosides

    Article • Current Protocols in Nucleic Acid Chemistry, June 2005, Wiley

    Dr Ivan Lavandera

  90. Enzymatic acylation reactions on ω-hydroxycyanohydrins

    Article • Tetrahedron, November 2004, Elsevier

    Dr Ivan Lavandera

  91. First Regioselective Enzymatic Alkoxycarbonylation of Primary Amines. Synthesis of Novel 5′- and 3′-Carbamates of Pyrimidine 3′,5′-Diaminonucleoside Derivatives Including BVDU Analogues.

    Article • ChemInform, July 2004, Wiley

    Dr Ivan Lavandera

  92. First Regioselective Enzymatic Alkoxycarbonylation of Primary Amines. Synthesis of Novel 5‘- and 3‘-Carbamates of Pyrimidine 3‘,5‘-Diaminonucleoside Derivatives Including BVDU Analogues

    Article • The Journal of Organic Chemistry, March 2004, American Chemical Society (ACS)

    Dr Ivan Lavandera, Prof. Dr. Miguel Ferrero

  93. Synthesis, Protonation Behavior, Conformational Analysis, and Regioselective Enzymatic Acylation of the Novel Diamino Analogue of (E)-5-(2-Bromovinyl)-2′-deoxyuridine (BVDU).

    Article • ChemInform, February 2004, Wiley

    Dr Ivan Lavandera

  94. Synthesis and Antiviral Activity Assay of Novel (E)-3′,5′-Diamino-5-(2-bromovinyl)-2′,3′,5′-trideoxyuridine

    Article • ChemInform, January 2004, Wiley

    Dr Ivan Lavandera

  95. Is the ring conformation the most critical parameter in lipase-catalysed acylation of cycloalkanols?

    Article • Organic & Biomolecular Chemistry, January 2004, Royal Society of Chemistry

    Dr Ivan Lavandera

  96. Synthesis, Protonation Behavior, Conformational Analysis, and Regioselective Enzymatic Acylation of the Novel Diamino Analogue of (E)-5-(2-Bromovinyl)-2′-deoxyuridine (BVDU)

    Article • Nucleosides Nucleotides & Nucleic Acids, October 2003, Taylor & Francis

    Dr Ivan Lavandera, Prof. Dr. Miguel Ferrero

  97. Synthesis and Antiviral Activity Assay of Novel (E)-3′,5′-Diamino-5-(2-bromovinyl)-2′,3′,5′-trideoxyuridine

    Article • Nucleosides Nucleotides & Nucleic Acids, October 2003, Taylor & Francis

    Dr Ivan Lavandera, Prof. Dr. Miguel Ferrero

  98. Novel and efficient syntheses of 3′,5′-diamino derivatives of 2′,3′,5′-trideoxycytidine and 2′,3′,5′-trideoxyadenosine. Protonation behavior of 3′,5′-diaminonucleosides

    Article • Tetrahedron, July 2003, Elsevier

    Dr Ivan Lavandera, Prof. Dr. Miguel Ferrero

  99. First Regioselective Enzymatic Acylation of Amino Groups Applied to Pyrimidine 3‘,5‘-Diaminonucleoside Derivatives. Improved Synthesis of Pyrimidine 3‘,5‘-Diamino-2‘,3‘,5‘-trideoxynucleosides

    Article • The Journal of Organic Chemistry, June 2001, American Chemical Society (ACS)

    Dr Ivan Lavandera, Prof. Dr. Miguel Ferrero