All Stories

  1. Article
    Enhanced alpha-amylase inhibition activity of amine-terminated PAMAM dendrimer stabilized pure copper-doped magnesium oxide nanoparticles
    Dr. João Rodrigues
  2. Article
    Carbon dots and dendrimers nanohybrids: from synthesis to applications
    Dr. João Rodrigues
  3. Article
    Toward public security monitoring: A perspective of optical molecular probes for phosgene and mustard gas detection
    Dr. João Rodrigues
  4. Article
    Redox‐Responsive Dendrimer Nanogels Enable Ultrasound‐Enhanced Chemoimmunotherapy of Pancreatic Cancer via Endoplasmic Reticulum Stress Amplification and Macrophage Polarization
    Dr. João Rodrigues
  5. Article
    Target-Specific Delivery and Bioavailability of Pharmaceuticals via Janus and Dendrimer Particles
    Dr. João Rodrigues
  6. Article
    Editorial: State-of-the-art rational nanodesign: from screening to theranostics and from bench to clinic
    Dr. João Rodrigues
  7. Article
    Dendrimer-mediated gene delivery to boost cancer immunotherapy
    Dr. João Rodrigues
  8. Article
    Biological Effects in Cancer Cells of Mono- and Bidentate Conjugation of Cisplatin on PAMAM Dendrimers: A Comparative Study
    Dr. João Rodrigues
  9. Article
    Dendrimers and dendrimer-based nano-objects for oncology applications
    Dr. João Rodrigues
  10. Article
    Aptamer-Mediated Antiviral Approaches for SARS-CoV-2
    Dr. João Rodrigues
  11. Article
    Modulation of Macrophages Using Nanoformulations with Curcumin to Treat Inflammatory Diseases: A Concise Review
    Dr. João Rodrigues
  12. Article
    Molecular engineered optical probes for chemical warfare agents and their mimics: Advances, challenges and perspectives
    Dr. João Rodrigues
  13. Article
    Development and challenges of cells- and materials-based tooth regeneration
    Dr. João Rodrigues
  14. Article
    Synthesis approach-dependent antiviral properties of silver nanoparticles and nanocomposites
    Dr. João Rodrigues
  15. Article
    A smartphone-adaptable fluorescent sensing tag for non-contact and visual monitoring of the freshness of fish
    Dr. João Rodrigues
  16. Article
    Green approaches for the synthesis of metal and metal oxide nanoparticles using microbial and plant extracts
    Dr. João Rodrigues
  17. Article
    Medical applications of biopolymer nanofibers
    Dr. João Rodrigues
  18. Article
    New insights into ruthenium(ii) metallodendrimers as anticancer drug nanocarriers: from synthesis to preclinic behaviour
    Dr. João Rodrigues
  19. Article
    Dendrimers and dendrimersomes as a novel tool for effective drug delivery applications
    Dr. João Rodrigues
  20. Article
    Dendrimer-Based Nanogels for Cancer Nanomedicine Applications
    Dr. João Rodrigues
  21. Article
    Carbosilane Glycodendrimers for Anticancer Drug Delivery: Synthetic Route, Characterization, and Biological Effect of Glycodendrimer–Doxorubicin Complexes
    Dr. João RodriguesMatěj Božik
  22. Article
    Polyester Dendrimers Based on Bis-MPA for Doxorubicin Delivery
    Dr. João Rodrigues
  23. Article
    Coumarin-based Fluorescent Probes for Bioimaging: Recent Applications and Developments
    Dr. João Rodrigues
  24. Article
    Polysaccharide-based nanomedicines for cancer immunotherapy: A review
    Dr. João Rodrigues
  25. Article
    First-in-class and best-in-class dendrimer nanoplatforms from concept to clinic: Lessons learned moving forward
    Dr. João Rodrigues
  26. Article
    Chemically heterogeneous carbon dots enhanced cholesterol detection by MALDI TOF mass spectrometry
    Dr. João Rodrigues
  27. Article
    Cytocompatible cellulose nanofibers from invasive plant species Agave americana L. and Ricinus communis L.: a renewable green source of highly crystalline nanocellulose
    Dr Radenka Krsmanovic WhiffenDr. João Rodrigues
  28. Article
    Engineered Fluorescent Carbon Dots and G4-G6 PAMAM Dendrimer Nanohybrids for Bioimaging and Gene Delivery
    Dr. João Rodrigues
  29. Article
    Use of Half-Generation PAMAM Dendrimers (G0.5–G3.5) with Carboxylate End-Groups to Improve the DACHPtCl2 and 5-FU Efficacy as Anticancer Drugs
    Dr. João Rodrigues
  30. Article
    Gas foaming of electrospun poly(L-lactide-co-caprolactone)/silk fibroin nanofiber scaffolds to promote cellular infiltration and tissue regeneration
    Dr. João Rodrigues
  31. Article
    Short X···N Halogen Bonds With Hexamethylenetetraamine as the Acceptor
    Dr. João Rodrigues
  32. Article
    Engineered non-invasive functionalized dendrimer/dendron-entrapped/complexed gold nanoparticles as a novel class of theranostic (radio)pharmaceuticals in cancer therapy
    Dr. João Rodrigues
  33. Article
    A dual-analytes responsive fluorescent probe for discriminative detection of ClO− and N2H4 in living cells
    Dr. João Rodrigues
  34. Article
    Detection of Ru potential metallodrug in human urine by MALDI-TOF mass spectrometry: Validation and options to enhance the sensitivity
    Dr. João RodriguesManuel Algarra
  35. Article
    Superstructured poly(amidoamine) dendrimer-based nanoconstructs as platforms for cancer nanomedicine: A concise review
    Dr. João Rodrigues
  36. Article
    Dendrimers toward Translational Nanotherapeutics: Concise Key Step Analysis
    Dr. João Rodrigues
  37. Article
    A Review on Thermoplastic or Thermosetting Polymeric Matrices Used in Polymeric Composites Manufactured with Banana Fibers from the Pseudostem
    Dr. João Rodrigues
  38. Article
    Polyethylenimine Nanogels Incorporated with Ultrasmall Iron Oxide Nanoparticles and Doxorubicin for MR Imaging-Guided Chemotherapy of Tumors
    Dr. João Rodrigues
  39. Article
    A glance over doxorubicin based-nanotherapeutics: From proof-of-concept studies to solutions in the market
    Dr. João Rodrigues
  40. Article
    Chemical Sensors towards Environmental Toxic Molecule Monitoring: Fluores-cent Probes for Detection of Thiophenol
    Dr. João Rodrigues
  41. Article
    Front cover
    Dr. João Rodrigues
  42. Article
    New insights into the blue intrinsic fluorescence of oxidized PAMAM dendrimers considering their use as bionanomaterials
    Dr. João Rodrigues
  43. Article
    Zwitterion-functionalized dendrimer-entrapped gold nanoparticles for serum-enhanced gene delivery to inhibit cancer cell metastasis
    Dr. João Rodrigues
  44. Article
    A fast responsive chromogenic and near-infrared fluorescence lighting-up probe for visual detection of toxic thiophenol in environmental water and living cells
    Dr. João Rodrigues
  45. Article
    In silico search, chemical characterization and immunogenic evaluation of amino-terminated G4-PAMAM-HIV peptide complexes using three-dimensional models of the HIV-1 gp120 protein
    Dr. João Rodrigues
  46. Article
    Exploration of biomedical dendrimer space based on in-vitro physicochemical parameters: key factor analysis (Part 1)
    Dr. João Rodrigues
  47. Article
    Exploration of biomedical dendrimer space based on in-vivo physicochemical parameters: Key factor analysis (Part 2)
    Dr. João Rodrigues
  48. Article
    A selective cascade reaction-based probe for colorimetric and ratiometric fluorescence detection of benzoyl peroxide in food and living cells
    Dr. João Rodrigues
  49. Article
    New anionic poly(alkylideneamine) dendrimers as microbicide agents against HIV-1 infection
    Dr. João Rodrigues
  50. Article
    PAMAM dendrimers: blood-brain barrier transport and neuronal uptake after focal brain ischemia
    Dr. João Rodrigues
  51. Article
    Multifunctional Dendrimer-Entrapped Gold Nanoparticles Conjugated with Doxorubicin for pH-Responsive Drug Delivery and Targeted Computed Tomography Imaging
    Dr. João Rodrigues
  52. Article
    Poly(alkylidenimine) Dendrimers Functionalized with the Organometallic Moiety [Ru(η5-C5H5)(PPh3)2]+ as Promising Drugs Against Cisplatin-Resistant Cancer Cells and Human Mesenchymal Stem Cells
    Dr. João Rodrigues
  53. Article
    Role of Dendrimers in the Development of New Dendritic Cells Immunotherapies Against HIV-1 Infection
    Dr. João Rodrigues
  54. Article
    Recent therapeutic applications of the theranostic principle with dendrimers in oncology
    Dr. João Rodrigues
  55. Article
    Present drug-likeness filters in medicinal chemistry during the hit and lead optimization process: how far can they be simplified?
    Dr. João Rodrigues
  56. Article
    Mechanical Properties of Alumina Nanofilled Polymeric Composites Cured with DDSA and MNA
    Dr. João Rodrigues
  57. Article
    Dendrimers in combination with natural products and analogues as anti-cancer agents
    Dr. João Rodrigues
  58. Article
    Bench-to-bedside translation of dendrimers: Reality or utopia? A concise analysis
    Dr. João Rodrigues
  59. Article
    Binding free energy calculations using MMPB/GBSA approaches for PAMAM-G4-drug complexes at neutral, basic and acid pH conditions
    Dr. João Rodrigues
  60. Article
    Principal Physicochemical Methods Used to Characterize Dendrimer Molecule Complexes Used as Genetic Therapy Agents, Nanovaccines or Drug Carriers
    Dr. João Rodrigues
  61. Article
    The influence of curing agents in the impact properties of epoxy resin nanocomposites
    Dr. João Rodrigues
  62. Article
    Laponite-based nanohybrids for enhanced solubility of dexamethasone and osteogenic differentiation of human mesenchymal stem cells
    Dr. João Rodrigues
  63. Article
    Laponite®: A key nanoplatform for biomedical applications?
    Dr. João RodriguesHelena Tomás
  64. Article
    Electrodeposition of polyaniline on self-assembled monolayers on graphite for the voltammetric detection of iron(II)
    Dr. João Rodrigues
  65. Article
    Design, synthesis and biological evaluation of Arylpiperazine-based novel Phthalimides: Active inducers of testicular germ cell apoptosis
    Dr. João RodriguesDr Jitender Kumar Bhardwaj
  66. Article
    Compound high-quality criteria: a new vision to guide the development of drugs, current situation
    Dr. João Rodrigues
  67. Article
    Fine tuning of the pH-sensitivity of laponite–doxorubicin nanohybrids by polyelectrolyte multilayer coating
    Dr. João Rodrigues
  68. Article
    Why and how have drug discovery strategies in pharma changed? What are the new mindsets?
    Dr. João Rodrigues
  69. Article
    Thermo/Redox/pH-stimulative nanogel delivery systems
    Dr. João Rodrigues
  70. Article
    Effect of irregular shaped nanoalumina on the enhancement of mechanical properties of epoxy resin nanocomposites using DDM as hardener
    Dr. João Rodrigues
  71. Article
    Gene delivery using dendrimer/pDNA complexes immobilized in electrospun fibers using the Layer-by-Layer technique
    Dr. João Rodrigues
  72. Article
    Biodegradable Polymer Nanogels for Drug/Nucleic Acid Delivery
    Dr. João Rodrigues
  73. Article
    PAMAM Dendrimer/pDNA Functionalized-Magnetic Iron Oxide
    Dr. João Rodrigues
  74. Article
    Octadecyl functionalized core–shell magnetic silica nanoparticle as a powerful nanocomposite sorbent to extract urinary volatile organic metabolites
    Dr. João Rodrigues
  75. Article
    Assembly of Peptides
    Dr. João RodriguesDr Nikolay Yu Gorobets
  76. Article
    Editorial (Thematic Issue: Self-Assembled Organic Nanostructures in Medicinal Chemistry: Advances and Applications)
    Dr. João Rodrigues
  77. Article
    Molecular wires - solid-state photoluminescence studies
    Kari RissanenDr. João Rodrigues
  78. Article
    Thermo/redox/pH-triple sensitive poly(N-isopropylacrylamide-co-acrylic acid) nanogels for anticancer drug delivery
    Dr. João Rodrigues
  79. Article
    RGD peptide-modified multifunctional dendrimer platform for drug encapsulation and targeted inhibition of cancer cells
    Dr. João Rodrigues
  80. Article
    Amphiphilic Polymer-Mediated Formation of Laponite-Based Nanohybrids with Robust Stability and pH Sensitivity for Anticancer Drug Delivery
    Dr. João Rodrigues
  81. Article
    An exploratory study to evaluate the potential of nanohydroxyapatite as a powerful sorbent for efficient extraction of volatile organic metabolites, potential biomarkers of cancer
    Professor José S. CâmaraDr. João Rodrigues
  82. Article
    Dendrimer-Assisted Formation of Fluorescent Nanogels for Drug Delivery and Intracellular Imaging
    Xiangyang ShiDr. João Rodrigues
  83. Article
    pH-sensitive Laponite®/doxorubicin/alginate nanohybrids with improved anticancer efficacy
    Dr. João Rodrigues
  84. Article
    Redox-Responsive Alginate Nanogels with Enhanced Anticancer Cytotoxicity
    Xiangyang ShiDr. João Rodrigues
  85. Article
    Antitumor Efficacy of Doxorubicin-Loaded Laponite/Alginate Hybrid Hydrogels
    Xiangyang ShiDr. João Rodrigues
  86. Article
    cis,cis,cis-(Acetato-κ2O,O′)bis[1,2-bis(diphenylphosphanyl)ethane-κ2P,P′]ruthenium(II) 0.75-trifluoromethanesulfonate 0.25-chloride
    Dr. João Rodrigues
  87. Article
    A convenient route for the preparation of the monohydride catalyst trans-[RuCl(H)(dppe)2] (dppe=Ph2PCH2CH2PPh2): Improved synthesis and crystal structure
    Dr. João Rodrigues
  88. Article
    Metallodendrimers for Nonlinear Optics
    Dr. João Rodrigues
  89. Article
    The Effect of PAMAM Dendrimers on Mesenchymal Stem Cell Viability and Differentiation
    Dr. João Rodrigues
  90. Article
    Insight into the role of N,N-dimethylaminoethyl methacrylate (DMAEMA) conjugation onto poly(ethylenimine): cell viability and gene transfection studies
    Dr. João RodriguesVisvaldas Kairys
  91. Article
    Calcium phosphate-mediated gene delivery using simulated body fluid (SBF)
    Dr. João Rodrigues
  92. Article
    Gene delivery using biodegradable polyelectrolyte microcapsules prepared through the layer-by-layer technique
    Dr. João Rodrigues
  93. Article
    ChemInform Abstract: Injectable and Biodegradable Hydrogels: Gelation, Biodegradation and Biomedical Applications
    Dr. João Rodrigues
  94. Article
    Injectable and biodegradable hydrogels: gelation, biodegradation and biomedical applications
    Dr. João Rodrigues
  95. Article
    ChemInform Abstract: Poly(alkylidenamines) Dendrimers as Scaffolds for the Preparation of Low‐Generation Ruthenium Based Metallodendrimers
    Dr. João Rodrigues
  96. Article
    Injectable hybrid laponite/alginate hydrogels for sustained release of methylene blue
    Dr. João Rodrigues
  97. Article
    Gene Delivery into Mesenchymal Stem Cells: A Biomimetic Approach Using RGD Nanoclusters Based on Poly(amidoamine) Dendrimers
    Dr. João Rodrigues
  98. Article
    Non-Viral Gene Delivery to Mesenchymal Stem Cells: Methods, Strategies and Application in Bone Tissue Engineering and Regeneration
    Dr. João Rodrigues
  99. Article
    How Do Nitriles Compare with Isoelectronic Alkynyl Groups in the Electronic Communication between Iron Centers Bridged by Phenylenebis- and -tris(nitrile) Ligands? An Electronic and Crystal-Structure Study
    Dr. João Rodrigues
  100. Article
    pH sensitive Laponite/alginate hybrid hydrogels: swelling behaviour and release mechanism
    Xiangyang ShiDr. João Rodrigues
  101. Article
    Metallodendrimers for medical applications
    Dr. João Rodrigues
  102. Article
    Receptor-Mediated Gene Delivery Using PAMAM Dendrimers Conjugated with Peptides Recognized by Mesenchymal Stem Cells
    Dr. João Rodrigues
  103. Article
    Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells
    Dr. João Rodrigues
  104. Article
    Nitrile Ruthenium Metallodendrimers
    Dr. João Rodrigues
  105. Article
    Visible-Light Photolytic Synthesis of Multinuclear and Dendritic Iron-Nitrile Cationic Complexes
    Dr. João Rodrigues
  106. Article
    4,4′-[Thiophene-2,5-diylbis(ethyne-2,1-diyl)]dibenzonitrile
    Dr. João Rodrigues
  107. Article
    Three 2,5-dialkoxy-1,4-diethynylbenzene derivatives
    Dr. João Rodrigues
  108. Article
    Syntheses and characterization of novel ruthenium complexes based on 1,3-dicyanobenzene
    Dr. João Rodrigues
  109. Article
    Trinuclear Aqua Cyano-Bridged Ruthenium Complex
    Dr. João Rodrigues
  110. Article
    trans-Bis[bis(diphenylphosphino)methane-κ2P,P′]dichlororuthenium(II) dichloromethane disolvate acetone hemisolvate hemihydrate
    Dr. João Rodrigues
  111. Article
    cis-Diazido[bis(diphenylphosphino)methane-κ2P,P′]ruthenium(II) dichloromethane 0.42-solvate
    Dr. João Rodrigues
  112. Article
    cis-[Bis(diphenylphosphino)ethane-κ2 P,P′]dichlororuthenium(II) dichloromethane disolvate
    Dr. João Rodrigues
  113. Article
    cis-Aquabis[bis(diphenylphosphino)ethane-κ2 P,P′]chlororuthenium(II) hexafluorophosphate dichloromethane sesquisolvate hemihydrate
    Dr. João Rodrigues
  114. Article
    From Simple Monopyridine Clusters [Mo 6 Br 13 (Py-R)][ n -Bu 4 N] and Hexapyridine Clusters [Mo 6 X 8 (Py-R) 6 ][OSO 2 CF 3 ] 4 (X = Br or I) to Cluster-Cored Organometallic Stars, Dendrons, and Dendrimers
    Dr. João Rodrigues
  115. Article
    Ruthenium Metallodendrimers Based on Nitrile-Functionalized Poly(alkylidene imine)s
    Dr. João Rodrigues
  116. Article
    Mo6Br8-Cluster-cored organometallic stars and dendrimers
    Dr. João Rodrigues
  117. Article
    Synthesis, characterization and crystal structure of the bimetallic cyano-bridged [(η5-C5H5)(PPh3)2Ru(μ-CN)Ru(PPh3)2(η5-C5H5)][PF6]
  118. Article
    Molecular structure and crystal packing of CpMRisonitriles (M= Ru, Fe;R= phosphines and TMEDA). How to obtain new solids for NLO
    Dr. João Rodrigues
  119. Article
    Organometallic Syntheses of Hexa- and Nonanitrile Ligands and Their Ruthenium Complexes
    Dr. João Rodrigues
  120. Article
    Second harmonic generation of η5-monocyclopentadienyl ruthenium p-benzonitrile derivatives by Kurtz powder technique. Crystal and molecular structure determinations of [Ru(η5-C5H5)((+)-DIOP)(p-NCC6H4NO2)][X], X=PF6−, CF3SO3− and [Ru(η5-C5H5)((+)-DIOP)(...
  121. Article
    Hyper-Rayleigh scattering study of η5-monocyclopentadienyl–metal complexes for second order non-linear optical materials
  122. Article
    Third-harmonic generation in organometallic ruthenium(II) derivatives containing coordinated p-substituted benzonitriles
    Dr. João Rodrigues
  123. Article
    Synthesis and characterization of η5-monocyclopentadienyl (p-nitrobenzonitrile)ruthenium(II) salts: Second harmonic generation powder efficiencies
    Dr. João Rodrigues