All Stories

  1. The location of stem cells in the human breast

    Article • The Journal of Pathology, November 2017, Wiley

    Dr Stuart A McDonald, Anieta M Sieuwerts, Biancastella Cereser

  2. Quantification of Crypt and Stem Cell Evolution in the Normal and Neoplastic Human Colon

    Article • Cell Reports, August 2014, Elsevier

    Dr Stuart A McDonald, Dr Trevor A Graham, Biancastella Cereser

  3. Barrett's origins from gastric mucosa

    Article • Gut, February 2014, BMJ

    Dr Stuart A McDonald, Professor Janusz Antoni Jankowski

  4. Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors

    Article • eLife, October 2013, eLife

    Dr Stuart A McDonald, Dr Trevor A Graham

  5. Clonal Selection and Persistence in Dysplastic Barrettʼs Esophagus and Intramucosal Cancers After Failed Radiofrequency Ablation

    Article • The American Journal of Gastroenterology, October 2013, Wolters Kluwer Health

    Dr Stuart A McDonald, Dr Trevor A Graham

  6. Crypt dysplasia in Barrett's oesophagus shows clonal identity between crypt and surface cells

    Article • The Journal of Pathology, August 2013, Wiley

    Dr Stuart A McDonald, Dr Trevor A Graham

  7. OC-030 Barrett’S Epithelium Shows Evidence of Gastric and Intestinal Differentiation Programmes but Preserves the Proliferative and Stem Cell Architecture of Gastric Glands

    Article • Gut, June 2013, BMJ

    Dr Stuart A McDonald

  8. Identification of Lineage-Uncommitted, Long-Lived, Label-Retaining Cells in Healthy Human Esophagus and Stomach, and in Metaplastic Esophagus

    Article • Gastroenterology, April 2013, Elsevier

    Dr Stuart A McDonald, Professor Janusz Antoni Jankowski

  9. Bullying at Barts

    Article • The Lancet, April 2012, Elsevier

    Dr Stuart A McDonald

  10. Field Cancerization in the Intestinal Epithelium of Patients With Crohn's Ileocolitis

    Article • Gastroenterology, April 2012, Elsevier

    Dr Stuart A McDonald, Dr Trevor A Graham

  11. Barrett's metaplasia glands are clonal, contain multiple stem cells and share a common squamous progenitor

    Article • Gut, December 2011, BMJ

    Dr Stuart A McDonald, Dr Trevor A Graham, Professor Janusz Antoni Jankowski

  12. Clonal architecture of human prostatic epithelium in benign and malignant conditions

    Article • The Journal of Pathology, August 2011, Wiley

    Dr Stuart A McDonald, Dr Trevor A Graham

  13. Field cancerization in the GI tract

    Article • Future Oncology, August 2011, Future Medicine

    Dr Stuart A McDonald, Dr Trevor A Graham

  14. The human urothelium consists of multiple clonal units, each maintained by a stem cell

    Article • The Journal of Pathology, July 2011, Wiley

    Dr Stuart A McDonald, Dr Trevor A Graham

  15. Use of Methylation Patterns to Determine Expansion of Stem Cell Clones in Human Colon Tissue

    Article • Gastroenterology, April 2011, Elsevier

    Dr Stuart A McDonald, Dr Trevor A Graham

  16. The Clonal Origins of Dysplasia From Intestinal Metaplasia in the Human Stomach

    Article • Gastroenterology, April 2011, Elsevier

    Dr Stuart A McDonald, Dr Trevor A Graham, Professor Janusz Antoni Jankowski

  17. 902 Investigating Clonal Competition in Barrett's Associated Tumorigenesis Using Spatial Maps of Genetic Heterogeneity

    Article • Gastroenterology, May 2010, Elsevier

    Dr Stuart A McDonald

  18. 947 Analysis of the Clonality of Barrett's Esophagus Glands Reveals They are Clonal Units and Establishes a Common Stem Cell for Glandular and Squamous Epithelium

    Article • Gastroenterology, May 2010, Elsevier

    Dr Stuart A McDonald

  19. T1738 Stem Cell Location Throughout the Human Gastrointestinal Tract as Defined by LGR5 mRNA in Situ Hybridisation

    Article • Gastroenterology, May 2010, Elsevier

    Dr Stuart A McDonald

  20. Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas

    Article • Gastroenterology, April 2010, Elsevier

    Dr Stuart A McDonald, Dr Trevor A Graham, Professor Janusz Antoni Jankowski

  21. The histogenesis of regenerative nodules in human liver cirrhosis

    Article • Hepatology, March 2010, Wolters Kluwer Health

    Dr Stuart A McDonald

  22. Protection of mitochondrial genome integrity: A new stem cell property?

    Article • Hepatology, July 2009, Wolters Kluwer Health

    Dr Stuart A McDonald

  23. Stem cells and solid cancers

    Article • Virchows Archiv, June 2009, Springer Science + Business Media

    Dr Stuart A McDonald, Dr Trevor A Graham

  24. A Methodological Approach to Tracing Cell Lineage in Human Epithelial Tissues

    Article • Stem Cells, June 2009, Oxford University Press (OUP)

    Dr Stuart A McDonald

  25. 484 Methylation and Clonality of Human Colonic Crypts

    Article • Gastroenterology, May 2009, Elsevier

    Dr Stuart A McDonald

  26. 487 Mapping Stem Cell Clones in Human Intestinal Crypts

    Article • Gastroenterology, May 2009, Elsevier

    Dr Stuart A McDonald

  27. M1620 The Saint Trial (Stem Cell Analysis and Identification By Iudr Labelling of Neoplastic Tissue); Identification of Barrett's Stem Cells

    Article • Gastroenterology, May 2009, Elsevier

    Dr Stuart A McDonald

  28. 1086 The Clonal Origins of Dysplasia from Metaplasia in the Human Stomach

    Article • Gastroenterology, May 2009, Elsevier

    Dr Stuart A McDonald

  29. Clonality, Founder Mutations, and Field Cancerization in Human Ulcerative Colitis–Associated Neoplasia

    Article • Gastroenterology, February 2009, Elsevier

    Dr Stuart A McDonald, Dr Trevor A Graham, Professor Janusz Antoni Jankowski

  30. Analysis of the clonal architecture of the human small intestinal epithelium establishes a common stem cell for all lineages and reveals a mechanism for the fixation and spread of mutations

    Article • The Journal of Pathology, January 2009, Wiley

    Dr Stuart A McDonald, Professor Janusz Antoni Jankowski

  31. Stem Cells in the Gastrointestinal Tract

    Article • January 2009, Elsevier

    Dr Stuart A McDonald

  32. Locating the stem cell niche and tracing hepatocyte lineages in human liver

    Article • Hepatology, December 2008, Wolters Kluwer Health

    Dr Stuart A McDonald

  33. Ectopic Expression of P-Cadherin Correlates with Promoter Hypomethylation Early in Colorectal Carcinogenesis and Enhanced Intestinal Crypt Fission In vivo

    Article • Cancer Research, October 2008, American Association for Cancer Research (AACR)

    Dr Stuart A McDonald, Professor Janusz Antoni Jankowski

  34. Molecular Biology of Gastroesophageal Cancers: The Role of Mutational Analysis in Prognosis

    Article • April 2008, Wiley

    Dr Stuart A McDonald

  35. T1770 Mitochondrial DNA Mutations May Shed Light On Clonal Expansion in Human Liver Tissue

    Article • Gastroenterology, April 2008, Elsevier

    Dr Stuart A McDonald

  36. W1747 Human Small Intestinal Crypts Are Clonal, Contain Multiple Stem Cells and Mutated Crypts Divide By Fission

    Article • Gastroenterology, April 2008, Elsevier

    Dr Stuart A McDonald

  37. Mechanisms of Field Cancerization in the Human Stomach: The Expansion and Spread of Mutated Gastric Stem Cells

    Article • Gastroenterology, February 2008, Elsevier

    Dr Stuart A McDonald, Professor Janusz Antoni Jankowski

  38. Detection of Intestinal Metaplasia in Barrett's Esophagus

    Article • The American Journal of Gastroenterology, October 2007, Wolters Kluwer Health

    Dr Stuart A McDonald, Professor Janusz Antoni Jankowski

  39. Detection of Intestinal Metaplasia in Barrett's Esophagus: An Observational Comparator Study Suggests the Need for a Minimum of Eight Biopsies

    Article • The American Journal of Gastroenterology, June 2007, Wolters Kluwer Health

    Dr Stuart A McDonald, Professor Janusz Antoni Jankowski

  40. Mechanisms of Disease: from stem cells to colorectal cancer

    Article • Nature Clinical Practice Gastroenterology &#38 Hepatology, May 2006, Springer Science + Business Media

    Dr Stuart A McDonald, Professor Janusz Antoni Jankowski

  41. Protection against the Early Acute Phase of Cryptosporidium parvum Infection Conferred by Interleukin‐4–Induced Expression of T Helper 1 Cytokines

    Article • The Journal of Infectious Diseases, September 2004, Oxford University Press (OUP)

    Dr Stuart A McDonald

  42. The role of interleukin (IL)-4 in the early control of murine cryptosporidiosis

    Article • Gastroenterology, April 2003, Elsevier

    Dr Stuart A McDonald

  43. Tumour necrosis factor alpha mediates resistance to Cryptosporidium parvum infection in enterocyte cell lines but is not required for protection in a mouse model of infection

    Article • Gastroenterology, April 2003, Elsevier

    Dr Stuart A McDonald

  44. An OX40 fusion protein prevents colitis in mice

    Article • Gastroenterology, April 1998, Elsevier

    Dr Stuart A McDonald

  45. Characterization of the mucosal cell‐mediated immune response in IL‐2 knockout mice before and after the onset of colitis

    Article • Immunology, May 1997

    Dr Stuart A McDonald