Professor Wim M De Borggraeve
Associatie KU Leuven
Professor, Chemistry
Belgium
My co-authors include
Dr Jesus Alcazar
Prof Yves Briers
Professor Carmen Burtea
My Publications
Rationalising Supramolecular Hydrogelation of Bis‐Urea‐Based Gelators through a Multisc...
ChemPlusChem
November 2019
Introduction of Aryl Fluorosulfates into the Realm of Catellani Reaction Substrates
The Journal of Organic Chemistry
November 2019
Modeling of Nanomolecular and Reticular Architectures with 6-fold Grooved, Programmable...
Journal of Chemical Education
October 2019
An Effective and Reusable Hyperbranched Polymer Immobilized Rhodium Catalyst for the Hy...
ACS Applied Polymer Materials
June 2019
Electrochemistry and Photoredox Catalysis: A Comparative Evaluation in Organic Synthesis
Molecules
June 2019
Ketone Synthesis by a Nickel-Catalyzed Dehydrogenative Cross-Coupling of Primary Alcohols
Journal of the American Chemical Society
April 2019
Synthesis of N-Acyl Sulfamates from Fluorosulfates and Amides
The Journal of Organic Chemistry
January 2019
Ball milling: a green technology for the preparation and functionalisation of nanocellu...
Nanoscale Advances
January 2019
Robust scalable synthesis of a bis-urea derivative forming thixotropic and cytocompatib...
Chemical Communications
January 2019
Chemical structure and biological properties of sulfated fucan from the sequential extr...
Carbohydrate Polymers
November 2018
Identification of fukinolic acid from Cimicifuga heracleifolia and its derivatives as...
International Journal of Antimicrobial Agents
July 2018
Direct Access to Aryl Bis(trifluoromethyl)carbinols from Aryl Bromides or Fluorosulfate...
Angewandte Chemie International Edition
May 2018
Direct Access to Aryl Bis(trifluoromethyl)carbinols from Aryl Bromides or Fluorosulfate...
Angewandte Chemie International Edition
May 2018
Methylated flavonoids as anti-seizure agents: Naringenin 4′,7-dimethyl ether attenuates...
Neurochemistry International
January 2018
Synthesis and peptide functionalization of hyperbranched poly(arylene oxindole) towards...
Polymer Chemistry
January 2018
Water Tolerant and Reusable Sulfonated Hyperbranched Poly(aryleneoxindole) Acid Catalys...
ChemistrySelect
October 2017
Ex Situ Generation of Sulfuryl Fluoride for the Synthesis of Aryl Fluorosulfates
Organic Letters
September 2017
A Convenient Multigram Synthesis of DABSO Using Sodium Sulfite as SO2 Source
Organic Process Research & Development
April 2017
Towards New Tricyclic Motifs: Intramolecular C-H Arylation as the Key Step in a Formal ...
European Journal of Organic Chemistry
March 2017
Discovery of a potent protein kinase D inhibitor: insights in the binding mode of pyraz...
MedChemComm
January 2017
Carbonylation as a novel method for the assembly of pyrazine based oligoamide alpha-hel...
Organic & Biomolecular Chemistry
January 2017
Nanocellulosic materials as bioinks for 3D bioprinting
Biomaterials Science
January 2017
The orthorhombic pseudopolymorph of tacrine hydrochloride
Acta Crystallographica Section B Structural Science Crystal Engineering and Materials
September 2016
Low-cost instant CO generation at room temperature using formic acid, mesyl chloride an...
Reaction Chemistry & Engineering
January 2016
Luminescence and Relaxometric Properties of Heteropolymetallic Metallostar Complexes wi...
European Journal of Inorganic Chemistry
August 2015
Improved detection of β-N-methylamino-l-alanine using N-hydroxysuccinimide ester of N-b...
Analytical and Bioanalytical Chemistry
March 2015
Synthesis of N -Hydroxypyrazin-2(1 H )-ones via Selective O -Debenzylation of 1-...
Journal of Flow Chemistry
March 2015
First Example of Alkyl–Aryl Negishi Cross-Coupling in Flow: Mild, Efficient and Clean I...
Journal of Flow Chemistry
March 2015
Facile azide formation via diazotransfer reaction in a copper tube flow reactor
Tetrahedron Letters
March 2015
The Zeamine Antibiotics Affect the Integrity of Bacterial Membranes
Applied and Environmental Microbiology
December 2014
First Example of a Continuous-Flow Carbonylation Reaction Using Aryl Formates as CO Pre...
Journal of Flow Chemistry
September 2014
Synthesis of 1-benzyloxypyrazin-2(1H)-one derivatives
Tetrahedron Letters
August 2014
Synthesis of 11-aza-artemisinin derivatives using the Ugi reaction and an evaluation of...
Tetrahedron Letters
August 2014
Synthesis of triterpenoid triazine derivatives from allobetulone and betulonic acid wit...
Bioorganic & Medicinal Chemistry
July 2014
Synthetic Protocol toward Fused Pyrazolone Derivatives via a Michael Addition and Reduc...
The Journal of Organic Chemistry
June 2014
8-HaloBODIPYs and Their 8-(C, N, O, S) Substituted Analogues: Solvent Dependent UV–Vis ...
The Journal of Physical Chemistry A
March 2014
Formation of amides when other approaches have failed
Chemical Communications
January 2014
Tanshinone IIA Exhibits Anticonvulsant Activity in Zebrafish and Mouse Seizure Models
ACS Chemical Neuroscience
November 2013
Diterpene glycosides from Stevia phlebophylla A. Gray
Carbohydrate Research
September 2013
Alpha-Helical Destabilization of the Bcl-2-BH4-Domain Peptide Abolishes Its Ability to ...
PLoS ONE
August 2013
Synthesis and in vitro evaluation of a PDT active BODIPY–NLS conjugate
Bioorganic & Medicinal Chemistry Letters
June 2013
Asymmetric Synthesis of 1-Aza-4-deoxypicropodophyllotoxin
Synlett
April 2013
Scaffold Hopping via a Transannular Rearrangement–Encompassing Cascade
Organic Letters
March 2013
Absolute configuration of 3-acetylbetulinic acid
Journal of Structural Chemistry
February 2013
Preparation and characterization of hydrogels based on homopolymeric fractions of sodiu...
Carbohydrate Polymers
January 2013
Total Synthesis of Septocylindrin B and C-Terminus Modified Analogues
PLoS ONE
December 2012
Fused derivatives of (iso)steviol via pericyclic reactions
Tetrahedron Letters
December 2012
Stevioside and Steviol as Starting Materials in Organic Synthesis
Current Organic Chemistry
September 2012
A Tripodal Ruthenium–Gadolinium Metallostar as a Potential αvβ3Integrin Specific Bimoda...
Inorganic Chemistry
June 2012
Anticonvulsant activity of bisabolene sesquiterpenoids of Curcuma longa in zebrafish an...
Epilepsy & Behavior
May 2012
Selective LC-MS/MS method for the identification of BMAA from its isomers in biological...
Analytical and Bioanalytical Chemistry
April 2012
Identification of a Small Molecule That Modulates Platelet Glycoprotein Ib-von Willebra...
Journal of Biological Chemistry
January 2012
An integrated fragment based screening approach for the discovery of small molecule mod...
Chemical Communications
January 2012
The C Terminus of Bax Inhibitor-1 Forms a Ca2+-permeable Channel Pore
Journal of Biological Chemistry
November 2011
A Heterobimetallic Ruthenium–Gadolinium Complex as a Potential Agent for Bimodal Imaging
Inorganic Chemistry
October 2011
Rational Design, Synthesis, and Spectroscopic and Photophysical Properties of a Visible...
Chemistry - A European Journal
August 2011
Isosteviol as a Starting Material in Organic Synthesis
Current Organic Chemistry
August 2011
A Modular Approach towards the Synthesis of Target-Specific MRI Contrast Agents
European Journal of Inorganic Chemistry
July 2011
Synthesis of the orthogonally protected amino alcohol Phaol and analogs
Journal of Peptide Science
April 2011
2-(4-Methoxybenzyl)-4,6-diphenyl-2,5-diazabicyclo[2.2.2]oct-5-en-3-one
Acta Crystallographica Section E Structure Reports Online
April 2011
Measuring cooperative Rev protein-protein interactions on Rev responsive RNA by fluores...
RNA Biology
March 2011
ChemInform Abstract: Synthesis of Pyridodiazepinediones by Using the Ugi Multicomponent...
ChemInform
January 2011
Triple Hyp→Pro replacement in integramide A, a peptaib inhibitor of HIV-1 integrase: Ef...
Biopolymers
January 2011
Influence of Reducing Carbohydrates on (6S)-5-Methyltetrahydrofolic Acid Degradation du...
Journal of Agricultural and Food Chemistry
May 2010
Direct functionalization of BODIPY dyes by oxidative nucleophilic hydrogen substitution...
Chemical Communications
January 2010
Generalized solvent scales as a tool for investigating solvent dependence of spectrosco...
Photochemical & Photobiological Sciences
January 2010
Synthesis and Substitution of 8-(4,6-Dichloropyrimidin-5-yl)-BODIPY
European Journal of Organic Chemistry
December 2009
Synthesis and Biological Evaluation of Bridged Analogues of the Platelet Aggregation In...
Letters in Drug Design & Discovery
October 2009
Flavonoids from Senecio viscosus
Chemistry of Natural Compounds
September 2009
Mechanism and Related Kinetics of 5-Methyltetrahydrofolic Acid Degradation during Combi...
Journal of Agricultural and Food Chemistry
August 2009
Synthesis and modifications of a small library of 1,4-benzodiazepin-3-ones toward poten...
Tetrahedron
June 2009
Synthesis of 5,5′-Dialkyl-6,6′-dichloro-2, 2′-bipyridines
Synthetic Communications
February 2009
Photophysics and stability of cyano-substituted boradiazaindacene dyes
Photochemical & Photobiological Sciences
January 2009
ChemInform Abstract: Synthesis of Pyrazino[1,2-a]benzimidazol-1(2H)ones via a Microwave...
ChemInform
December 2008
Structural property investigations of 1-[2-(2-methoxyphenyl)ethyl]piperidinium chloride...
Journal of Molecular Structure
November 2008
Synthesis of Highly Functionalized 2(1H)-Pyrazinone 3-Carboxamide Scaffolds
Organic Letters
October 2008
Synthesis of pyrazino[1,2-a]benzimidazol-1(2H)ones via a microwave assisted Buchwald–Ha...
Tetrahedron
August 2008
Ratiometric, Fluorescent BODIPY Dye with Aza Crown Ether Functionality: Synthesis, Solv...
The Journal of Physical Chemistry A
July 2008
Matrix-isolation FT-IR and theoretical investigation of the competitive intramolecular ...
Journal of Molecular Structure
May 2008
Spirocyclic Pyridoazepine Analogues of Galanthamine: Synthesis, Modelling Studies and E...
European Journal of Organic Chemistry
May 2008
ATR-IR spectroscopic study of the structural changes in the hydrophobic region of ICPAN...
Journal of Molecular Structure
April 2008
Synthesis and Biological Evaluation of Methylene-Bridged Analogs of the Potent Cannabin...
European Journal of Organic Chemistry
March 2008
trans-Chlorido[6-chloro-4-(4-methoxybenzyl)-3-oxo-3,4-dihydropyrazin-2-yl]bis(triphenyl...
Acta Crystallographica Section E Structure Reports Online
December 2007
Matrix-isolation FT-IR and theoretical investigation of the vibrational properties of t...
Journal of Molecular Structure
November 2007
Synthesis of Methylene-Bridged Analogues of Biologically Active Pteridine Derivatives.
ChemInform
October 2007
Synthesis of Spirocyclic Pyridoazepines as Analogues of Galanthamine by Nucleophilic Ar...
European Journal of Organic Chemistry
October 2007
Synthesis of 2(1H)-Pyrazinone Phosphonates via an Arbuzov-Type Reaction.
ChemInform
June 2007
Synthesis of Methylene-Bridged Analogues of Biologically Active Pteridine Derivatives
European Journal of Organic Chemistry
June 2007
Conformational Analysis of TOAC-Labelled Alamethicin F50/5 Analogues
Chemistry & Biodiversity
June 2007
Design, Synthesis and Evaluation of Serine Protease Inhibitor Analogues
European Journal of Organic Chemistry
June 2007
Diastereoselective Diels—Alder Additions of Ethene to Substituted Homochiral 2(1H)-Pyra...
ChemInform
May 2007
Synthesis of 2(1 H )-Pyrazinone Phosphonates via an Arbuzov-type Reaction
The Journal of Organic Chemistry
February 2007
Diastereoselective Diels–Alder Additions of Ethene to Substituted Homochiral 2(1H)-Pyra...
European Journal of Organic Chemistry
February 2007
Photophysics of 3,5-diphenoxy substituted BODIPY dyes in solution
Photochemical & Photobiological Sciences
January 2007
3,5-Dihalo-2(1H)-pyrazinones: Versatile Scaffolds in Organic Synthesis
ChemInform
November 2006
3,5-Dihalo-2(1 H )-pyrazinones: Versatile Scaffolds in Organic Synthesis
Synthesis
September 2006
Photophysical properties of an on/off fluorescent pH indicator excitable with visible l...
Journal of Photochemistry and Photobiology A Chemistry
September 2006
Synthesis of 1,5-disubstituted 4-haloimidazoles from α-aminonitriles
Tetrahedron Letters
July 2006
Solvent and pH Dependent Fluorescent Properties of a Dimethylaminostyryl Borondipyrrome...
The Journal of Physical Chemistry A
May 2006
Design, Synthesis, and Preferred Conformation of Peptides Based on a Highly Constrained...
January 2006
Preferred 3D-Structure of Peptides Rich in a Severely Conformationally Restricted Cyclo...
Chemistry - A European Journal
January 2006
Structure based design of simplified analogues of insect kinins
Tetrahedron
October 2005
Development of New Amino(oxo)piperidinecarboxylate Scaffolds and Their Evaluation as -T...
European Journal of Organic Chemistry
July 2005
BODIPY-Based Hydroxyaryl Derivatives as Fluorescent pH Probes
The Journal of Organic Chemistry
May 2005
Expanding the substitution pattern of 2(1H)-pyrazinones via Suzuki and Heck reactions
Tetrahedron
April 2005
Synthesis of sidechain adapted β-turn mimics for modifying the C-terminus of substance P
Tetrahedron Letters
March 2005
Turn and Helical Peptide Handedness Governed Exclusively by Side-Chain Chiral Centers
Journal of the American Chemical Society
February 2005
Synthesis of Novel Functionalised Symmetric Bi-2(1 H )-pyrazinones
Synlett
January 2005
Design and synthesis of novel type VI-like β-turn mimetics. Diversity at the i+1 and th...
Tetrahedron
December 2004
New Routes for the Synthesis of 3- and 5-Substituted 2(1H)-Pyrazinones.
ChemInform
June 2004
Acid catalysed methanolysis of 2,5-diazabicyclo[2.2.2]octane-3,6-diones: scope and limi...
Tetrahedron Letters
May 2004
New routes for the synthesis of 3- and 5-substituted 2(1H)-pyrazinones
Tetrahedron Letters
February 2004
Stereoselective transformation of pyrazinones into substituted analogues of cis-5-amino...
Tetrahedron
June 2003
Development of a Functionalizable External β-Turn Mimic Based on a cis-Fused 1,7-Naphth...
European Journal of Organic Chemistry
May 2003
High-Speed Microwave-Promoted Hetero-Diels−Alder Reactions of 2(1H)-Pyrazinones in Ioni...
The Journal of Organic Chemistry
November 2002
Stereoselective intramolecular Diels–Alder reactions of 3-alkenyl(oxy)-2(1H)-pyrazinones
Tetrahedron Letters
January 2002
Intramolecular Diels–Alder reactions of N-alkenyl-2(1H)-pyrazinones: generation of a no...
Tetrahedron Letters
October 2001
Synthesis of a conformationally restricted dipeptide analogue and its evaluation as a β...
Tetrahedron Letters
August 2001
Divergent pathways in the intramolecular diels-alder reaction of 2(1H)-pyrazinones subs...
Tetrahedron
December 1999
