All Stories

  1. Cell binding tropism is a pivotal determinant of HEV's zoonotic transmission to humans

    Article • Proceedings of the National Academy of Sciences, October 2024, Proceedings of the National Academy of Sciences

    Wenshi Wang

  2. The distinct spatiotemporal evolutionary landscape of HBV and HDV largely determines the unique epidemic features of HDV globally

    Article • Molecular Phylogenetics and Evolution, August 2024, Elsevier

    Wenshi Wang

  3. Drug repurposing screen identifies vidofludimus calcium and pyrazofurin as novel chemical entities for the development of hepatitis E interventions

    Article • Virologica Sinica, February 2024, Elsevier

    Wenshi Wang

  4. miR-26a exerts broad-spectrum antiviral effects via the enhancement of RIG-I-mediated type I interferon response by targeting USP15

    Article • Microbiology Spectrum, January 2024, ASM Journals

    Wenshi Wang

  5. Molecular determinants within the C-termini of L-HDAg that regulate hepatitis D virus replication and assembly

    Article • JHEP Reports, January 2024, Elsevier

    Wenshi Wang

  6. Combating pan-coronavirus infection by indomethacin through simultaneously inhibiting viral replication and inflammatory response

    Article • iScience, September 2023, Elsevier

    Wenshi Wang

  7. In vitro cell culture models to study hepatitis B and D virus infection

    Article • Frontiers in Microbiology, April 2023, Frontiers

    Wenshi Wang

  8. Assembly and infection efficacy of hepatitis B virus surface protein exchanges in 8 hepatitis D virus genotype isolates

    Article • Journal of Hepatology, August 2021, Elsevier

    Wenshi Wang

  9. LGR5 marks targetable tumor-initiating cells in mouse liver cancer

    Article • Nature Communications, April 2020, Springer Science + Business Media

    Wenshi Wang

  10. MDA5 against enteric viruses through induction of interferon-like response partially via the JAK-STAT cascade

    Article • Antiviral Research, April 2020, Elsevier

    Wenshi Wang

  11. Estimating the Global Prevalence, Disease Progression, and Clinical Outcome of Hepatitis Delta Virus Infection

    Article • The Journal of Infectious Diseases, November 2019, Oxford University Press (OUP)

    Wenshi Wang

  12. Pregnane X receptor activation constrains mucosal NF-κB activity in active inflammatory bowel disease

    Article • PLOS One, October 2019, PLOS

    Wenshi Wang

  13. A functional variant in the miR‐142 promoter modulating its expression and conferring risk of Alzheimer disease

    Article • Human Mutation, August 2019, Wiley

    Dr ir Wilfred van IJcken, Wenshi Wang

  14. Suppression of pyrimidine biosynthesis by targeting DHODH enzyme robustly inhibits rotavirus replication

    Article • Antiviral Research, July 2019, Elsevier

    Wenshi Wang

  15. The Interplay between Host Innate Immunity and Hepatitis E Virus

    Article • Viruses, June 2019, MDPI AG

    Wenshi Wang

  16. The Eukaryotic Translation Initiation Factor 4F Complex Restricts Rotavirus Infection via Regulating the Expression of IRF1 and IRF7

    Article • International Journal of Molecular Sciences, March 2019, MDPI AG

    Wenshi Wang

  17. Dichotomal functions of phosphorylated and unphosphorylated STAT1 in hepatocellular carcinoma

    Article • Journal of Molecular Medicine, November 2018, Springer Science + Business Media

    Wenshi Wang

  18. Recombinant identification, molecular classification and proposed reference genomes for hepatitis delta virus

    Article • Journal of Viral Hepatitis, October 2018, Wiley

    Wenshi Wang

  19. Conservation and variation of the hepatitis E virus ORF2 capsid protein

    Article • Gene, October 2018, Elsevier

    Wenshi Wang

  20. Mitochondrial electron transport chain complex III sustains hepatitis E virus replication and represents an antiviral target

    Article • The FASEB Journal, August 2018, Wiley

    Qiuwei Pan, Wenshi Wang

  21. 6-Thioguanine inhibits rotavirus replication through suppression of Rac1 GDP/GTP cycling

    Article • Antiviral Research, August 2018, Elsevier

    Wenshi Wang

  22. TNF-α exerts potent anti-rotavirus effects via the activation of classical NF-κB pathway

    Article • Virus Research, July 2018, Elsevier

    Wenshi Wang

  23. IRF-1, RIG-I and MDA5 display potent antiviral activities against norovirus coordinately induced by different types of interferons

    Article • Antiviral Research, July 2018, Elsevier

    Wenshi Wang

  24. Basal interferon signaling and therapeutic use of interferons in controlling rotavirus infection in human intestinal cells and organoids

    Article • Scientific Reports, May 2018, Springer Science + Business Media

    Wenshi Wang

  25. The RNA genome of hepatitis E virus robustly triggers an antiviral interferon response

    Article • Hepatology, April 2018, Wolters Kluwer Health

    Wenshi Wang

  26. Immunity against hepatitis E virus infection: Implications for therapy and vaccine development

    Article • Reviews in Medical Virology, December 2017, Wiley

    Wenshi Wang

  27. Dynamics of Proliferative and Quiescent Stem Cells in Liver Homeostasis and Injury

    Article • Gastroenterology, October 2017, Elsevier

    Wenshi Wang

  28. Epigenome-Wide Association Study Identifies Methylation Sites Associated With Liver Enzymes and Hepatic Steatosis

    Article • Gastroenterology, October 2017, Elsevier

    Wenshi Wang

  29. Inhibition of Calcineurin or IMP Dehydrogenase Exerts Moderate to Potent Antiviral Activity against Norovirus Replication

    Article • Antimicrobial Agents and Chemotherapy, August 2017, ASM Journals

    Qiuwei Pan, Wenshi Wang

  30. Genotype-specific acquisition, evolution and adaptation of characteristic mutations in hepatitis E virus

    Article • Virulence, July 2017, Taylor & Francis

    Wenshi Wang

  31. Transcriptional Regulation of Antiviral Interferon-Stimulated Genes

    Article • Trends in Microbiology, July 2017, Elsevier

    Wenshi Wang

  32. Nucleoside analogue 2’-C-methylcytidine inhibits hepatitis E virus replication but antagonizes ribavirin

    Article • Archives of Virology, June 2017, Springer Science + Business Media

    Wenshi Wang

  33. PI3K-Akt-mTOR axis sustains rotavirus infection via the 4E-BP1 mediated autophagy pathway and represents an antiviral target

    Article • Virulence, May 2017, Taylor & Francis

    Qiuwei Pan, Wenshi Wang

  34. RIG-I is a key antiviral interferon-stimulated gene against hepatitis E virus regardless of interferon production

    Article • Hepatology, May 2017, Wiley

    Wenshi Wang

  35. Unphosphorylated ISGF3 drives constitutive expression of interferon-stimulated genes to protect against viral infections

    Article • Science Signaling, April 2017, American Association for the Advancement of Science

    Wenshi Wang

  36. Biological or pharmacological activation of protein kinase C alpha constrains hepatitis E virus replication

    Article • Antiviral Research, April 2017, Elsevier

    Johan Neyts, Wenshi Wang

  37. Direct-acting antiviral therapy for hepatitis E virus?

    Article • The Lancet Gastroenterology & Hepatology, March 2017, Elsevier

    Wenshi Wang

  38. Hepatitis E Virus Infects Neurons and Brains

    Article • The Journal of Infectious Diseases, February 2017, Oxford University Press (OUP)

    Wenshi Wang

  39. Noncanonical Antiviral Mechanisms of ISGs: Dispensability of Inducible Interferons

    Article • Trends in Immunology, January 2017, Elsevier

    Wenshi Wang

  40. Distinct Antiviral Potency of Sofosbuvir Against Hepatitis C and E Viruses

    Article • Gastroenterology, December 2016, Elsevier

    Wenshi Wang

  41. The global burden of hepatitis E outbreaks: a systematic review

    Article • Liver International, September 2016, Wiley

    Wenshi Wang

  42. Mycophenolic acid potently inhibits rotavirus infection with a high barrier to resistance development

    Article • Antiviral Research, September 2016, Elsevier

    Wenshi Wang

  43. IFN regulatory factor 1 restricts hepatitis E virus replication by activating STAT1 to induce antiviral IFN‐stimulated genes

    Article • The FASEB Journal, June 2016, Wiley

    Wenshi Wang

  44. Targeting Viral Polymerase for Treating Hepatitis E Infection: How Far Are We?

    Article • Gastroenterology, June 2016, Elsevier

    Wenshi Wang

  45. Convergent Transcription of Interferon-stimulated Genes by TNF-α and IFN-α Augments Antiviral Activity against HCV and HEV

    Article • Scientific Reports, May 2016, Springer Science + Business Media

    Wenshi Wang

  46. Cross Talk between Nucleotide Synthesis Pathways with Cellular Immunity in Constraining Hepatitis E Virus Replication

    Article • Antimicrobial Agents and Chemotherapy, May 2016, ASM Journals

    Qiuwei Pan, Wenshi Wang

  47. Disparity of basal and therapeutically activated interferon signalling in constraining hepatitis E virus infection

    Article • Journal of Viral Hepatitis, December 2015, Wiley

    Wenshi Wang

  48. Requirement of the eukaryotic translation initiation factor 4F complex in hepatitis E virus replication

    Article • Antiviral Research, December 2015, Elsevier

    Wenshi Wang

  49. In silico prediction and in vitro identification of bluetongue virus 4 VP5 protein B-cell epitopes

    Article • Applied Microbiology and Biotechnology, December 2013, Springer Science + Business Media

    Wenshi Wang

  50. Antibodies generated by immunization with the NS1 protein of West Nile virus confer partial protection against lethal Japanese encephalitis virus challenge

    Article • Veterinary Microbiology, September 2013, Elsevier

    Wenshi Wang

  51. Identification of a linear B-cell epitope within the Bluetongue virus serotype 8 NS2 protein using a phage-displayed random peptide library

    Article • Veterinary Immunology and Immunopathology, August 2013, Elsevier

    Wenshi Wang

  52. Comprehensive Mapping of Common Immunodominant Epitopes in the Eastern Equine Encephalitis Virus E2 Protein Recognized by Avian Antibody Responses

    Article • PLOS One, July 2013, PLOS

    Wenshi Wang

  53. Analysis of murine B-cell epitopes on Eastern equine encephalitis virus glycoprotein E2

    Article • Applied Microbiology and Biotechnology, March 2013, Springer Science + Business Media

    Wenshi Wang

  54. Identification of two novel BTV16-specific B cell epitopes using monoclonal antibodies against the VP2 protein

    Article • Applied Microbiology and Biotechnology, March 2013, Springer Science + Business Media

    Wenshi Wang

  55. Identification of three novel linear B-cell epitopes on the VP5 protein of BTV16

    Article • Veterinary Microbiology, March 2013, Elsevier

    Wenshi Wang

  56. Identification of a novel bluetongue virus 1-specific B-cell epitope using a monoclonal antibody against the VP2 protein

    Article • Archives of Virology, January 2013, Springer Science + Business Media

    Wenshi Wang

  57. Monoclonal Antibodies Against VP7 of Bluetongue Virus

    Article • Hybridoma, December 2012, Mary Ann Liebert Inc

    Wenshi Wang