All Stories

  1. Characterization of equine cytochrome P450: role of CYP3A in the metabolism of diazepam

    Article • Journal of Veterinary Pharmacology and Therapeutics, March 2016, Wiley

    Dr Wageh S Darwish, Dr Wageh Sobhy Darwish

  2. Distribution and health risk assessment of organochlorine pesticides (OCPs) residue in edible cattle tissues from northeastern part of Egypt: High accumulation level of OCPs in tongue

    Article • Chemosphere, February 2016, Elsevier

    Dr Wageh S Darwish, Dr Wageh Sobhy Darwish

  3. β-carotene and retinol contents in the meat of herbivorous ungulates with a special reference to their public health importance

    Article • Journal of Veterinary Medical Science, January 2016, Japanese Society of Veterinary Science

    Dr Wageh S Darwish, Dr Wageh Sobhy Darwish

  4. Reliability of stable Pb isotopes to identify Pb sources and verifying biological fractionation of Pb isotopes in goats and chickens

    Article • Environmental Pollution, January 2016, Elsevier

    Dr Wageh S Darwish, Dr Wageh Sobhy Darwish

  5. Constitutive Effects of Lead on Aryl Hydrocarbon Receptor Gene Battery and Protection by β-carotene and Ascorbic Acid in Human HepG2 Cells

    Article • Journal of Food Science, December 2015, Wiley

    Dr Wageh S Darwish, Dr Wageh Sobhy Darwish

  6. Metal extent in blood of livestock from Dandora dumping site, Kenya: Source identification of Pb exposure by stable isotope analysis

    Article • Environmental Pollution, October 2015, Elsevier

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  7. Cytochrome P450-mediated warfarin metabolic ability is not a critical determinant of warfarin sensitivity in avian species: In vitro assays in several birds and in vivo assays in chicken

    Article • Environmental Toxicology and Chemistry, August 2015, Wiley

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  8. Metabolic Activation of Heterocyclic Amines and Expression of Xenobiotic-Metabolizing Enzymes in the Gastrointestinal Tract of Rats

    Article • Journal of Food Science, June 2015, Wiley

    Dr Wageh S Darwish, Dr Wageh Sobhy Darwish

  9. Are red gourami (Colisa labiosa) low xenobiotic metabolizers? Elucidation of in vivo pharmacokinetics of pyrene as a model substrate

    Article • Environmental Toxicology and Pharmacology, May 2015, Elsevier

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  10. Prevalence, Molecular Characterization and Antibiotic Susceptibility ofEscherichia ColiIsolated from Duck Meat and Giblets

    Article • Journal of Food Safety, April 2015, Wiley

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  11. Characterization and tissue distribution of conjugated metabolites of pyrene in the rat

    Article • Journal of Veterinary Medical Science, January 2015, Japanese Society of Veterinary Science

    Dr Wageh S Darwish, Dr Wageh Sobhy Darwish

  12. Identification of interspecific differences in phase II reactions: Determination of metabolites in the urine of 16 mammalian species exposed to environmental pyrene

    Article • Environmental Toxicology and Chemistry, July 2014, Wiley

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  13. The Effect of Copper on the mRNA Expression Profile of Xenobiotic-Metabolizing Enzymes in Cultured Rat H4-II-E Cells

    Article • Biological Trace Element Research, March 2014, Springer Science + Business Media

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  14. An Overview on Mycotoxin Contamination of Foods in Africa

    Article • Journal of Veterinary Medical Science, January 2014, Japanese Society of Veterinary Science

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  15. Molecular evaluation of a new highly sensitive aryl hydrocarbon receptor in ostriches

    Article • Poultry Science, June 2013, Oxford University Press (OUP)

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  16. Effects of environmental lead contamination on cattle in a lead/zinc mining area: Changes in cattle immune systems on exposure to lead in vivo and in vitro

    Article • Environmental Toxicology and Chemistry, August 2012, Wiley

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  17. Astaxanthin rich crude extract of Haematococcus pluvialis induces cytochrome P450 1A1 mRNA by activating aryl hydrocarbon receptor in rat hepatoma H4IIE cells

    Article • Food Chemistry, January 2012, Elsevier

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  18. Astaxanthin can alter CYP1A-dependent activities via two different mechanisms: Induction of protein expression and inhibition of NADPH P450 reductase dependent electron transfer

    Article • Food and Chemical Toxicology, June 2011, Elsevier

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  19. Carotenoids as regulators for inter-species difference in cytochrome P450 1A expression and activity in ungulates and rats

    Article • Food and Chemical Toxicology, November 2010, Elsevier

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  20. Mutagenic activation and detoxification of benzo[a]pyrene in vitro by hepatic cytochrome P450 1A1 and phase II enzymes in three meat-producing animals

    Article • Food and Chemical Toxicology, August 2010, Elsevier

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  21. High expression of the mRNA of cytochrome P450 and phase II enzymes in the lung and kidney tissues of cattle

    Article • animal, June 2010, Cambridge University Press

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  22. Metabolic Activation of Heterocyclic Amines and Expression of CYP1A1 in the Tongue

    Article • Toxicological Sciences, March 2010, Oxford University Press (OUP)

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  23. Expression and Sequence of CYP1A1 in the Camel

    Article • Journal of Veterinary Medical Science, January 2010, Japanese Society of Veterinary Science

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  24. Identification and Phylogenetic Analysis of Novel Cytochrome P450 1A Genes from Ungulate Species

    Article • Journal of Veterinary Medical Science, January 2010, Japanese Society of Veterinary Science

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish

  25. Cytochrome P450 1A-Dependent Activities in Deer, Cattle and Horses

    Article • Journal of Veterinary Medical Science, January 2010, Japanese Society of Veterinary Science

    Dr Wageh Sobhy Darwish, Dr Wageh S Darwish